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[Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease].

Identifieur interne : 000424 ( PubMed/Curation ); précédent : 000423; suivant : 000425

[Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease].

Auteurs : S M Gou [République populaire de Chine] ; T. Yin ; J X Xiong ; T. Peng ; Y. Li ; H S Wu

Source :

RBID : pubmed:32107909

Abstract

Objective: To explorethe proper protective measures for pancreaticdiseases treatment during theoutbreak of 2019 coronavirus disease(COVID-19). Method: Clinical data of four cases of patients that suffered COVID-19from February 2(nd), 2020 to February 9(th), 2020 in pancreatic surgery were reviewed.After the first patientscuffednosocomial infection of COVID-19, the general protective measures in our department wereupdated.Only one patient was admitted to each room alone, with no more than one caregiver.The body temperature of care givers was measuredtwice a day.Primary protections were applied to all staff.The floor was sterilized using disinfectant with an effective chlorine concentration of 1000 mg/L.The protective measures for interventional procedures were as follow.Primary protection was applied to the operators ofcentral venipuncture catheter, percutaneous abdominal/pleural drainage, percutaneous retroperitoneal drainage, percutaneous transhepatic cholangial drainage and other surgical procedures with local anesthesiaand epidural anesthesia.Secondary protection was applied to the operators of endoscopic retrograde cholangiopancreatography and surgical procedures with general anesthesia. Results: During Feb 2(nd), 2020 to Feb 9(th), 2020, four patients in our department were diagnosed with COVID-19, of which one was died of COVID-19, two were cured, and one is still in hospital for COVID-19.After the update ofprotective measures in our department, no more nosocomial infection of COVID-19occurred.Two central venipuncture catheter, three percutaneous abdominal/pleural drainage, one percutaneous retroperitoneal drainage, one percuteneous transhepatic cholecyst drainage and one open surgery with general anesthesia were performed with no infection of operators. Conclusions: The caregivers of patients are potential infection source of COVID-19.Enhanced protective measures including the management measures of caregivers can decrease the risk of nosocomial infection of COVID-19.

DOI: 10.3760/cma.j.cn112139-20200224-00123
PubMed: 32107909

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<title xml:lang="en">[Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease].</title>
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<name sortKey="Gou, S M" sort="Gou, S M" uniqKey="Gou S" first="S M" last="Gou">S M Gou</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022</wicri:regionArea>
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<name sortKey="Yin, T" sort="Yin, T" uniqKey="Yin T" first="T" last="Yin">T. Yin</name>
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<name sortKey="Xiong, J X" sort="Xiong, J X" uniqKey="Xiong J" first="J X" last="Xiong">J X Xiong</name>
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<name sortKey="Peng, T" sort="Peng, T" uniqKey="Peng T" first="T" last="Peng">T. Peng</name>
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<name sortKey="Li, Y" sort="Li, Y" uniqKey="Li Y" first="Y" last="Li">Y. Li</name>
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<name sortKey="Wu, H S" sort="Wu, H S" uniqKey="Wu H" first="H S" last="Wu">H S Wu</name>
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<nlm:affiliation>Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022</wicri:regionArea>
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<name sortKey="Yin, T" sort="Yin, T" uniqKey="Yin T" first="T" last="Yin">T. Yin</name>
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<name sortKey="Xiong, J X" sort="Xiong, J X" uniqKey="Xiong J" first="J X" last="Xiong">J X Xiong</name>
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<name sortKey="Peng, T" sort="Peng, T" uniqKey="Peng T" first="T" last="Peng">T. Peng</name>
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<author>
<name sortKey="Li, Y" sort="Li, Y" uniqKey="Li Y" first="Y" last="Li">Y. Li</name>
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<name sortKey="Wu, H S" sort="Wu, H S" uniqKey="Wu H" first="H S" last="Wu">H S Wu</name>
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<series>
<title level="j">Zhonghua wai ke za zhi [Chinese journal of surgery]</title>
<idno type="ISSN">0529-5815</idno>
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<date when="2020" type="published">2020</date>
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<div type="abstract" xml:lang="en">
<b>Objective:</b>
To explorethe proper protective measures for pancreaticdiseases treatment during theoutbreak of 2019 coronavirus disease(COVID-19).
<b>Method:</b>
Clinical data of four cases of patients that suffered COVID-19from February 2(nd), 2020 to February 9(th), 2020 in pancreatic surgery were reviewed.After the first patientscuffednosocomial infection of COVID-19, the general protective measures in our department wereupdated.Only one patient was admitted to each room alone, with no more than one caregiver.The body temperature of care givers was measuredtwice a day.Primary protections were applied to all staff.The floor was sterilized using disinfectant with an effective chlorine concentration of 1000 mg/L.The protective measures for interventional procedures were as follow.Primary protection was applied to the operators ofcentral venipuncture catheter, percutaneous abdominal/pleural drainage, percutaneous retroperitoneal drainage, percutaneous transhepatic cholangial drainage and other surgical procedures with local anesthesiaand epidural anesthesia.Secondary protection was applied to the operators of endoscopic retrograde cholangiopancreatography and surgical procedures with general anesthesia.
<b>Results:</b>
During Feb 2(nd), 2020 to Feb 9(th), 2020, four patients in our department were diagnosed with COVID-19, of which one was died of COVID-19, two were cured, and one is still in hospital for COVID-19.After the update ofprotective measures in our department, no more nosocomial infection of COVID-19occurred.Two central venipuncture catheter, three percutaneous abdominal/pleural drainage, one percutaneous retroperitoneal drainage, one percuteneous transhepatic cholecyst drainage and one open surgery with general anesthesia were performed with no infection of operators.
<b>Conclusions:</b>
The caregivers of patients are potential infection source of COVID-19.Enhanced protective measures including the management measures of caregivers can decrease the risk of nosocomial infection of COVID-19.</div>
</front>
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<pubmed>
<MedlineCitation Status="Publisher" Owner="NLM">
<PMID Version="1">32107909</PMID>
<DateRevised>
<Year>2020</Year>
<Month>02</Month>
<Day>28</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Print">0529-5815</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>58</Volume>
<Issue>0</Issue>
<PubDate>
<Year>2020</Year>
<Month>Feb</Month>
<Day>28</Day>
</PubDate>
</JournalIssue>
<Title>Zhonghua wai ke za zhi [Chinese journal of surgery]</Title>
<ISOAbbreviation>Zhonghua Wai Ke Za Zhi</ISOAbbreviation>
</Journal>
<ArticleTitle>[Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease].</ArticleTitle>
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<MedlinePgn>E006</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.3760/cma.j.cn112139-20200224-00123</ELocationID>
<Abstract>
<AbstractText>
<b>Objective:</b>
To explorethe proper protective measures for pancreaticdiseases treatment during theoutbreak of 2019 coronavirus disease(COVID-19).
<b>Method:</b>
Clinical data of four cases of patients that suffered COVID-19from February 2(nd), 2020 to February 9(th), 2020 in pancreatic surgery were reviewed.After the first patientscuffednosocomial infection of COVID-19, the general protective measures in our department wereupdated.Only one patient was admitted to each room alone, with no more than one caregiver.The body temperature of care givers was measuredtwice a day.Primary protections were applied to all staff.The floor was sterilized using disinfectant with an effective chlorine concentration of 1000 mg/L.The protective measures for interventional procedures were as follow.Primary protection was applied to the operators ofcentral venipuncture catheter, percutaneous abdominal/pleural drainage, percutaneous retroperitoneal drainage, percutaneous transhepatic cholangial drainage and other surgical procedures with local anesthesiaand epidural anesthesia.Secondary protection was applied to the operators of endoscopic retrograde cholangiopancreatography and surgical procedures with general anesthesia.
<b>Results:</b>
During Feb 2(nd), 2020 to Feb 9(th), 2020, four patients in our department were diagnosed with COVID-19, of which one was died of COVID-19, two were cured, and one is still in hospital for COVID-19.After the update ofprotective measures in our department, no more nosocomial infection of COVID-19occurred.Two central venipuncture catheter, three percutaneous abdominal/pleural drainage, one percutaneous retroperitoneal drainage, one percuteneous transhepatic cholecyst drainage and one open surgery with general anesthesia were performed with no infection of operators.
<b>Conclusions:</b>
The caregivers of patients are potential infection source of COVID-19.Enhanced protective measures including the management measures of caregivers can decrease the risk of nosocomial infection of COVID-19.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Gou</LastName>
<ForeName>S M</ForeName>
<Initials>SM</Initials>
<AffiliationInfo>
<Affiliation>Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Yin</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Xiong</LastName>
<ForeName>J X</ForeName>
<Initials>JX</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Peng</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Li</LastName>
<ForeName>Y</ForeName>
<Initials>Y</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Wu</LastName>
<ForeName>H S</ForeName>
<Initials>HS</Initials>
</Author>
</AuthorList>
<Language>chi</Language>
<PublicationTypeList>
<PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2020</Year>
<Month>02</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo>
<Country>China</Country>
<MedlineTA>Zhonghua Wai Ke Za Zhi</MedlineTA>
<NlmUniqueID>0153611</NlmUniqueID>
<ISSNLinking>0529-5815</ISSNLinking>
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<CitationSubset>IM</CitationSubset>
<OtherAbstract Type="Publisher" Language="chi">
<AbstractText>
<b>目的:</b>
探讨新型冠状病毒肺炎疫情下胰腺外科诊疗活动的开展方式及感染防控方法。
<b>方法:</b>
收集2020年2月2日至2月9日华中科技大学同济医学院附属协和医院胰腺外科收治的4例院内感染新型冠状病毒肺炎的住院患者的临床资料。发生院内感染后,病区一般防护策略升级。患者单间收治,每天监测陪护人员体温。医务人员严格按一级防护要求实施防护,病区地面用有效含氯浓度1 000 mg/L的消毒液喷洒消毒。有创操作操作流程自疫情发生以来均按以下防护要求防护:中心静脉穿刺置管、经皮胸腔或腹腔穿刺引流、经皮腹膜后穿刺引流在病区内完成,操作人员按一级防护要求防护;经皮肝穿胆道或胆囊置管引流在介入手术室完成,操作人员按一级防护要求防护。尽量避免经内镜逆行胰胆管造影(ERCP)操作,对不可替代的ERCP操作,操作人员按二级防护要求防护。手术麻醉方式选择的顺序分别为局部麻醉、硬膜外麻醉与全身麻醉。局部麻醉或硬膜外麻醉手术的操作人员按一级防护要求防护,全身麻醉手术的操作人员按二级防护要求防护,发生院内感染前后有创操作流程未升级。
<b>结果:</b>
4例院内感染患者中,1例死亡,2例转入感染隔离病房治疗后治愈出院,1例仍在感染隔离病房治疗。自升级防护措施后,我科共有22例患者住院治疗。其中行中心静脉穿刺置管术2例、经皮胸腔或腹腔穿刺引流3例,经皮腹膜后穿刺引流1例,经皮胆囊穿刺引流1例,开放手术治疗1例,截至2020年2月26日我科未再发生患者感染事件。整个疫情期间未发生有创操作人员感染事件。
<b>结论:</b>
在新型冠状病毒肺炎疫情下陪护人员的输入感染可能是院内感染的重大风险。完善病区一般防护策略与有创操作防护策略,并加强对陪护人员的教育与管理,是有序开展胰腺外科常规诊疗活动的前提。.</AbstractText>
</OtherAbstract>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">2019 coronavirus disease</Keyword>
<Keyword MajorTopicYN="N">Coronavirus infections</Keyword>
<Keyword MajorTopicYN="N">Nosocomial infection</Keyword>
<Keyword MajorTopicYN="N">Novel coronavirus pneumonia</Keyword>
<Keyword MajorTopicYN="N">Pancreatic disease</Keyword>
<Keyword MajorTopicYN="N">Prevention of infection</Keyword>
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<Year>2020</Year>
<Month>2</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed">
<Year>2020</Year>
<Month>2</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2020</Year>
<Month>2</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList>
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