Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.
Identifieur interne : 000163 ( PubMed/Curation ); précédent : 000162; suivant : 000164Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.
Auteurs : Huijun Chen [République populaire de Chine] ; Juanjuan Guo [République populaire de Chine] ; Chen Wang [République populaire de Chine] ; Fan Luo [République populaire de Chine] ; Xuechen Yu [République populaire de Chine] ; Wei Zhang [États-Unis] ; Jiafu Li [République populaire de Chine] ; Dongchi Zhao [République populaire de Chine] ; Dan Xu [République populaire de Chine] ; Qing Gong [République populaire de Chine] ; Jing Liao [République populaire de Chine] ; Huixia Yang [République populaire de Chine] ; Wei Hou [République populaire de Chine] ; Yuanzhen Zhang [République populaire de Chine]Source :
- Lancet (London, England) [ 1474-547X ] ; 2020.
Abstract
Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. Limited data are available for pregnant women with COVID-19 pneumonia. This study aimed to evaluate the clinical characteristics of COVID-19 in pregnancy and the intrauterine vertical transmission potential of COVID-19 infection.
DOI: 10.1016/S0140-6736(20)30360-3
PubMed: 32151335
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.</title><author><name sortKey="Chen, Huijun" sort="Chen, Huijun" uniqKey="Chen H" first="Huijun" last="Chen">Huijun Chen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Guo, Juanjuan" sort="Guo, Juanjuan" uniqKey="Guo J" first="Juanjuan" last="Guo">Juanjuan Guo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Chen" sort="Wang, Chen" uniqKey="Wang C" first="Chen" last="Wang">Chen Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Luo, Fan" sort="Luo, Fan" uniqKey="Luo F" first="Fan" last="Luo">Fan Luo</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Xuechen" sort="Yu, Xuechen" uniqKey="Yu X" first="Xuechen" last="Yu">Xuechen Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jiafu" sort="Li, Jiafu" uniqKey="Li J" first="Jiafu" last="Li">Jiafu Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Dongchi" sort="Zhao, Dongchi" uniqKey="Zhao D" first="Dongchi" last="Zhao">Dongchi Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Paediatrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Xu, Dan" sort="Xu, Dan" uniqKey="Xu D" first="Dan" last="Xu">Dan Xu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Gong, Qing" sort="Gong, Qing" uniqKey="Gong Q" first="Qing" last="Gong">Qing Gong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Liao, Jing" sort="Liao, Jing" uniqKey="Liao J" first="Jing" last="Liao">Jing Liao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Huixia" sort="Yang, Huixia" uniqKey="Yang H" first="Huixia" last="Yang">Huixia Yang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China. Electronic address: yanghuixia@bjmu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Hou, Wei" sort="Hou, Wei" uniqKey="Hou W" first="Wei" last="Hou">Wei Hou</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China. Electronic address: houwei@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Yuanzhen" sort="Zhang, Yuanzhen" uniqKey="Zhang Y" first="Yuanzhen" last="Zhang">Yuanzhen Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China. Electronic address: zhangyuanzhen@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32151335</idno><idno type="pmid">32151335</idno><idno type="doi">10.1016/S0140-6736(20)30360-3</idno><idno type="wicri:Area/PubMed/Corpus">000163</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000163</idno><idno type="wicri:Area/PubMed/Curation">000163</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000163</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.</title><author><name sortKey="Chen, Huijun" sort="Chen, Huijun" uniqKey="Chen H" first="Huijun" last="Chen">Huijun Chen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Guo, Juanjuan" sort="Guo, Juanjuan" uniqKey="Guo J" first="Juanjuan" last="Guo">Juanjuan Guo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Chen" sort="Wang, Chen" uniqKey="Wang C" first="Chen" last="Wang">Chen Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Luo, Fan" sort="Luo, Fan" uniqKey="Luo F" first="Fan" last="Luo">Fan Luo</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Xuechen" sort="Yu, Xuechen" uniqKey="Yu X" first="Xuechen" last="Yu">Xuechen Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jiafu" sort="Li, Jiafu" uniqKey="Li J" first="Jiafu" last="Li">Jiafu Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Dongchi" sort="Zhao, Dongchi" uniqKey="Zhao D" first="Dongchi" last="Zhao">Dongchi Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Paediatrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Xu, Dan" sort="Xu, Dan" uniqKey="Xu D" first="Dan" last="Xu">Dan Xu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Gong, Qing" sort="Gong, Qing" uniqKey="Gong Q" first="Qing" last="Gong">Qing Gong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Liao, Jing" sort="Liao, Jing" uniqKey="Liao J" first="Jing" last="Liao">Jing Liao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Huixia" sort="Yang, Huixia" uniqKey="Yang H" first="Huixia" last="Yang">Huixia Yang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China. Electronic address: yanghuixia@bjmu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Hou, Wei" sort="Hou, Wei" uniqKey="Hou W" first="Wei" last="Hou">Wei Hou</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China. Electronic address: houwei@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Yuanzhen" sort="Zhang, Yuanzhen" uniqKey="Zhang Y" first="Yuanzhen" last="Zhang">Yuanzhen Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China. Electronic address: zhangyuanzhen@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei</wicri:regionArea></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="eISSN">1474-547X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. Limited data are available for pregnant women with COVID-19 pneumonia. This study aimed to evaluate the clinical characteristics of COVID-19 in pregnancy and the intrauterine vertical transmission potential of COVID-19 infection.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">32151335</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1474-547X</ISSN><JournalIssue CitedMedium="Internet"><Volume>395</Volume><Issue>10226</Issue><PubDate><Year>2020</Year><Month>Mar</Month><Day>07</Day></PubDate></JournalIssue><Title>Lancet (London, England)</Title><ISOAbbreviation>Lancet</ISOAbbreviation></Journal><ArticleTitle>Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.</ArticleTitle><Pagination><MedlinePgn>809-815</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0140-6736(20)30360-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S0140-6736(20)30360-3</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. Limited data are available for pregnant women with COVID-19 pneumonia. This study aimed to evaluate the clinical characteristics of COVID-19 in pregnancy and the intrauterine vertical transmission potential of COVID-19 infection.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Clinical records, laboratory results, and chest CT scans were retrospectively reviewed for nine pregnant women with laboratory-confirmed COVID-19 pneumonia (ie, with maternal throat swab samples that were positive for severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) who were admitted to Zhongnan Hospital of Wuhan University, Wuhan, China, from Jan 20 to Jan 31, 2020. Evidence of intrauterine vertical transmission was assessed by testing for the presence of SARS-CoV-2 in amniotic fluid, cord blood, and neonatal throat swab samples. Breastmilk samples were also collected and tested from patients after the first lactation.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">All nine patients had a caesarean section in their third trimester. Seven patients presented with a fever. Other symptoms, including cough (in four of nine patients), myalgia (in three), sore throat (in two), and malaise (in two), were also observed. Fetal distress was monitored in two cases. Five of nine patients had lymphopenia (<1·0 × 10⁹ cells per L). Three patients had increased aminotransferase concentrations. None of the patients developed severe COVID-19 pneumonia or died, as of Feb 4, 2020. Nine livebirths were recorded. No neonatal asphyxia was observed in newborn babies. All nine livebirths had a 1-min Apgar score of 8-9 and a 5-min Apgar score of 9-10. Amniotic fluid, cord blood, neonatal throat swab, and breastmilk samples from six patients were tested for SARS-CoV-2, and all samples tested negative for the virus.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">The clinical characteristics of COVID-19 pneumonia in pregnant women were similar to those reported for non-pregnant adult patients who developed COVID-19 pneumonia. Findings from this small group of cases suggest that there is currently no evidence for intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia in late pregnancy.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Hubei Science and Technology Plan, Wuhan University Medical Development Plan.</AbstractText><CopyrightInformation>Copyright © 2020 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Huijun</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guo</LastName><ForeName>Juanjuan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Chen</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luo</LastName><ForeName>Fan</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Xuechen</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Wei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Jiafu</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Dongchi</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Paediatrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Dan</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gong</LastName><ForeName>Qing</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liao</LastName><ForeName>Jing</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Huixia</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China. Electronic address: yanghuixia@bjmu.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hou</LastName><ForeName>Wei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Virology/Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, China. Electronic address: houwei@whu.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yuanzhen</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Clinical Medicine Research Centre of Prenatal Diagnosis and Birth Health in Hubei Province, Wuhan, Hubei, China. Electronic address: zhangyuanzhen@whu.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>02</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Lancet</MedlineTA><NlmUniqueID>2985213R</NlmUniqueID><ISSNLinking>0140-6736</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Lancet. 2020 Mar 7;395(10226):760-762</RefSource><PMID Version="1">32151334</PMID></CommentsCorrections></CommentsCorrectionsList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>02</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>02</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>02</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32151335</ArticleId><ArticleId IdType="pii">S0140-6736(20)30360-3</ArticleId><ArticleId IdType="doi">10.1016/S0140-6736(20)30360-3</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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