Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.
Identifieur interne : 000585 ( PubMed/Corpus ); précédent : 000584; suivant : 000586Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.
Auteurs : Nanshan Chen ; Min Zhou ; Xuan Dong ; Jieming Qu ; Fengyun Gong ; Yang Han ; Yang Qiu ; Jingli Wang ; Ying Liu ; Yuan Wei ; Jia'An Xia ; Ting Yu ; Xinxin Zhang ; Li ZhangSource :
- Lancet (London, England) [ 1474-547X ] ; 2020.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, China (epidemiology), Comorbidity, Coronavirus Infections (complications), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (therapy), Cough (epidemiology), Cough (virology), Disease Outbreaks, Dyspnea (epidemiology), Dyspnea (virology), Female, Fever (epidemiology), Fever (virology), Humans, Male, Middle Aged, Pneumonia, Viral (complications), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Pneumonia, Viral (therapy), Prognosis, Radiography, Thoracic, Retrospective Studies, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology), Tomography, X-Ray Computed, Young Adult.
- MESH :
- geographic , epidemiology : China.
- complications : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Cough, Dyspnea, Fever, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- virology : Cough, Dyspnea, Fever, Severe Acute Respiratory Syndrome.
- Adult, Aged, Aged, 80 and over, Comorbidity, Disease Outbreaks, Female, Humans, Male, Middle Aged, Prognosis, Radiography, Thoracic, Retrospective Studies, Tomography, X-Ray Computed, Young Adult.
Abstract
In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia.
DOI: 10.1016/S0140-6736(20)30211-7
PubMed: 32007143
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.</title><author><name sortKey="Chen, Nanshan" sort="Chen, Nanshan" uniqKey="Chen N" first="Nanshan" last="Chen">Nanshan Chen</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhou, Min" sort="Zhou, Min" uniqKey="Zhou M" first="Min" last="Zhou">Min Zhou</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Xuan" sort="Dong, Xuan" uniqKey="Dong X" first="Xuan" last="Dong">Xuan Dong</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qu, Jieming" sort="Qu, Jieming" uniqKey="Qu J" first="Jieming" last="Qu">Jieming Qu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</nlm:affiliation></affiliation></author><author><name sortKey="Gong, Fengyun" sort="Gong, Fengyun" uniqKey="Gong F" first="Fengyun" last="Gong">Fengyun Gong</name><affiliation><nlm:affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Han, Yang" sort="Han, Yang" uniqKey="Han Y" first="Yang" last="Han">Yang Han</name><affiliation><nlm:affiliation>Science and Education Department, Wuhan Jinyintan Hospital, Wuhan, China; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qiu, Yang" sort="Qiu, Yang" uniqKey="Qiu Y" first="Yang" last="Qiu">Yang Qiu</name><affiliation><nlm:affiliation>State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Jingli" sort="Wang, Jingli" uniqKey="Wang J" first="Jingli" last="Wang">Jingli Wang</name><affiliation><nlm:affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Ying" sort="Liu, Ying" uniqKey="Liu Y" first="Ying" last="Liu">Ying Liu</name><affiliation><nlm:affiliation>The Office of Drug Clinical Trial Institution, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Yuan" sort="Wei, Yuan" uniqKey="Wei Y" first="Yuan" last="Wei">Yuan Wei</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Xia, Jia An" sort="Xia, Jia An" uniqKey="Xia J" first="Jia'An" last="Xia">Jia'An Xia</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Yu, Ting" sort="Yu, Ting" uniqKey="Yu T" first="Ting" last="Yu">Ting Yu</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Xinxin" sort="Zhang, Xinxin" uniqKey="Zhang X" first="Xinxin" last="Zhang">Xinxin Zhang</name><affiliation><nlm:affiliation>Research Laboratory of Clinical Virology, Ruijin Hospital and Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China; Clinical Research Center, Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address: zhangx@shsmu.edu.cn.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Li" sort="Zhang, Li" uniqKey="Zhang L" first="Li" last="Zhang">Li Zhang</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China. Electronic address: zhangli080806@163.com.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32007143</idno><idno type="pmid">32007143</idno><idno type="doi">10.1016/S0140-6736(20)30211-7</idno><idno type="wicri:Area/PubMed/Corpus">000585</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000585</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.</title><author><name sortKey="Chen, Nanshan" sort="Chen, Nanshan" uniqKey="Chen N" first="Nanshan" last="Chen">Nanshan Chen</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhou, Min" sort="Zhou, Min" uniqKey="Zhou M" first="Min" last="Zhou">Min Zhou</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Xuan" sort="Dong, Xuan" uniqKey="Dong X" first="Xuan" last="Dong">Xuan Dong</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qu, Jieming" sort="Qu, Jieming" uniqKey="Qu J" first="Jieming" last="Qu">Jieming Qu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</nlm:affiliation></affiliation></author><author><name sortKey="Gong, Fengyun" sort="Gong, Fengyun" uniqKey="Gong F" first="Fengyun" last="Gong">Fengyun Gong</name><affiliation><nlm:affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Han, Yang" sort="Han, Yang" uniqKey="Han Y" first="Yang" last="Han">Yang Han</name><affiliation><nlm:affiliation>Science and Education Department, Wuhan Jinyintan Hospital, Wuhan, China; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qiu, Yang" sort="Qiu, Yang" uniqKey="Qiu Y" first="Yang" last="Qiu">Yang Qiu</name><affiliation><nlm:affiliation>State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Jingli" sort="Wang, Jingli" uniqKey="Wang J" first="Jingli" last="Wang">Jingli Wang</name><affiliation><nlm:affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Ying" sort="Liu, Ying" uniqKey="Liu Y" first="Ying" last="Liu">Ying Liu</name><affiliation><nlm:affiliation>The Office of Drug Clinical Trial Institution, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Yuan" sort="Wei, Yuan" uniqKey="Wei Y" first="Yuan" last="Wei">Yuan Wei</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Xia, Jia An" sort="Xia, Jia An" uniqKey="Xia J" first="Jia'An" last="Xia">Jia'An Xia</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Yu, Ting" sort="Yu, Ting" uniqKey="Yu T" first="Ting" last="Yu">Ting Yu</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Xinxin" sort="Zhang, Xinxin" uniqKey="Zhang X" first="Xinxin" last="Zhang">Xinxin Zhang</name><affiliation><nlm:affiliation>Research Laboratory of Clinical Virology, Ruijin Hospital and Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China; Clinical Research Center, Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address: zhangx@shsmu.edu.cn.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Li" sort="Zhang, Li" uniqKey="Zhang L" first="Li" last="Zhang">Li Zhang</name><affiliation><nlm:affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China. Electronic address: zhangli080806@163.com.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="eISSN">1474-547X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>China (epidemiology)</term><term>Comorbidity</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (therapy)</term><term>Cough (epidemiology)</term><term>Cough (virology)</term><term>Disease Outbreaks</term><term>Dyspnea (epidemiology)</term><term>Dyspnea (virology)</term><term>Female</term><term>Fever (epidemiology)</term><term>Fever (virology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (therapy)</term><term>Prognosis</term><term>Radiography, Thoracic</term><term>Retrospective Studies</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Tomography, X-Ray Computed</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Cough</term><term>Dyspnea</term><term>Fever</term><term>Pneumonia, Viral</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Cough</term><term>Dyspnea</term><term>Fever</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Comorbidity</term><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prognosis</term><term>Radiography, Thoracic</term><term>Retrospective Studies</term><term>Tomography, X-Ray Computed</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32007143</PMID><DateCompleted><Year>2020</Year><Month>03</Month><Day>13</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1474-547X</ISSN><JournalIssue CitedMedium="Internet"><Volume>395</Volume><Issue>10223</Issue><PubDate><Year>2020</Year><Month>02</Month><Day>15</Day></PubDate></JournalIssue><Title>Lancet (London, England)</Title><ISOAbbreviation>Lancet</ISOAbbreviation></Journal><ArticleTitle>Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.</ArticleTitle><Pagination><MedlinePgn>507-513</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0140-6736(20)30211-7</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S0140-6736(20)30211-7</ELocationID><Abstract><AbstractText Label="BACKGROUND">In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia.</AbstractText><AbstractText Label="METHODS">In this retrospective, single-centre study, we included all confirmed cases of 2019-nCoV in Wuhan Jinyintan Hospital from Jan 1 to Jan 20, 2020. Cases were confirmed by real-time RT-PCR and were analysed for epidemiological, demographic, clinical, and radiological features and laboratory data. Outcomes were followed up until Jan 25, 2020.</AbstractText><AbstractText Label="FINDINGS">Of the 99 patients with 2019-nCoV pneumonia, 49 (49%) had a history of exposure to the Huanan seafood market. The average age of the patients was 55·5 years (SD 13·1), including 67 men and 32 women. 2019-nCoV was detected in all patients by real-time RT-PCR. 50 (51%) patients had chronic diseases. Patients had clinical manifestations of fever (82 [83%] patients), cough (81 [82%] patients), shortness of breath (31 [31%] patients), muscle ache (11 [11%] patients), confusion (nine [9%] patients), headache (eight [8%] patients), sore throat (five [5%] patients), rhinorrhoea (four [4%] patients), chest pain (two [2%] patients), diarrhoea (two [2%] patients), and nausea and vomiting (one [1%] patient). According to imaging examination, 74 (75%) patients showed bilateral pneumonia, 14 (14%) patients showed multiple mottling and ground-glass opacity, and one (1%) patient had pneumothorax. 17 (17%) patients developed acute respiratory distress syndrome and, among them, 11 (11%) patients worsened in a short period of time and died of multiple organ failure.</AbstractText><AbstractText Label="INTERPRETATION">The 2019-nCoV infection was of clustering onset, is more likely to affect older males with comorbidities, and can result in severe and even fatal respiratory diseases such as acute respiratory distress syndrome. In general, characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia. Further investigation is needed to explore the applicability of the MuLBSTA score in predicting the risk of mortality in 2019-nCoV infection.</AbstractText><AbstractText Label="FUNDING">National Key R&D Program of China.</AbstractText><CopyrightInformation>Copyright © 2020 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Nanshan</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Min</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Xuan</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qu</LastName><ForeName>Jieming</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gong</LastName><ForeName>Fengyun</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Han</LastName><ForeName>Yang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Science and Education Department, Wuhan Jinyintan Hospital, Wuhan, China; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qiu</LastName><ForeName>Yang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Jingli</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Infection Disease Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Ying</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>The Office of Drug Clinical Trial Institution, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wei</LastName><ForeName>Yuan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xia</LastName><ForeName>Jia'an</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Ting</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xinxin</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Research Laboratory of Clinical Virology, Ruijin Hospital and Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China; Clinical Research Center, Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address: zhangx@shsmu.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Li</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Tuberculosis and Respiratory Department, Wuhan Jinyintan Hospital, Wuhan, China. Electronic address: zhangli080806@163.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>01</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Lancet</MedlineTA><NlmUniqueID>2985213R</NlmUniqueID><ISSNLinking>0140-6736</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C000657245">COVID-19</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003371" MajorTopicYN="N">Cough</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004417" MajorTopicYN="N">Dyspnea</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005334" MajorTopicYN="N">Fever</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013902" MajorTopicYN="N">Radiography, Thoracic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>01</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>01</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>01</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>2</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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|texte= Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.
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