Discovering drugs to treat coronavirus disease 2019 (COVID-19).
Identifieur interne : 000184 ( PubMed/Corpus ); précédent : 000183; suivant : 000185Discovering drugs to treat coronavirus disease 2019 (COVID-19).
Auteurs : Liying Dong ; Shasha Hu ; Jianjun GaoSource :
- Drug discoveries & therapeutics [ 1881-784X ] ; 2020.
English descriptors
- KwdEn :
- Alanine (analogs & derivatives), Alanine (pharmacology), Amides (pharmacology), Antiviral Agents (chemistry), Antiviral Agents (pharmacology), Betacoronavirus (drug effects), Betacoronavirus (physiology), Chloroquine (pharmacology), Clinical Studies as Topic, Coronavirus Infections (drug therapy), Coronavirus Infections (virology), Drug Discovery, Humans, Indoles (pharmacology), Pyrazines (pharmacology), Ribonucleotides (pharmacology), Virus Replication (drug effects).
- MESH :
- chemical , analogs & derivatives : Alanine.
- chemical , chemistry : Antiviral Agents.
- chemical , pharmacology : Alanine, Amides, Antiviral Agents, Chloroquine, Indoles, Pyrazines, Ribonucleotides.
- drug effects : Betacoronavirus, Virus Replication.
- drug therapy : Coronavirus Infections.
- physiology : Betacoronavirus.
- virology : Coronavirus Infections.
- Clinical Studies as Topic, Drug Discovery, Humans.
Abstract
The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2.
DOI: 10.5582/ddt.2020.01012
PubMed: 32147628
Links to Exploration step
pubmed:32147628Le document en format XML
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Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32147628</PMID><DateCompleted><Year>2020</Year><Month>03</Month><Day>16</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>16</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1881-784X</ISSN><JournalIssue CitedMedium="Internet"><Volume>14</Volume><Issue>1</Issue><PubDate><Year>2020</Year></PubDate></JournalIssue><Title>Drug discoveries & therapeutics</Title><ISOAbbreviation>Drug Discov Ther</ISOAbbreviation></Journal><ArticleTitle>Discovering drugs to treat coronavirus disease 2019 (COVID-19).</ArticleTitle><Pagination><MedlinePgn>58-60</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.5582/ddt.2020.01012</ELocationID><Abstract><AbstractText>The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Liying</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, Shandong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hu</LastName><ForeName>Shasha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Jianjun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, Shandong, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal 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