Initial clinical features of suspected Coronavirus Disease 2019 in two emergency departments outside of Hubei, China.
Identifieur interne : 000046 ( PubMed/Corpus ); précédent : 000045; suivant : 000047Initial clinical features of suspected Coronavirus Disease 2019 in two emergency departments outside of Hubei, China.
Auteurs : Wanbo Zhu ; Kai Xie ; Hui Lu ; Lei Xu ; Shusheng Zhou ; Shiyuan FangSource :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Abstract
With an increasing number of Coronavirus Disease 2019 (COVID-19) cases outside of Hubei, emergency departments (EDs) and fever clinics are facing challenges posed by the large number of admissions of patients suspected to have COVID-19. Therefore, it is of crucial importance to study the initial clinical features of patients, to better differentiate between infected and uninfected patients outside Hubei.
DOI: 10.1002/jmv.25763
PubMed: 32167181
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Initial clinical features of suspected Coronavirus Disease 2019 in two emergency departments outside of Hubei, China.</title><author><name sortKey="Zhu, Wanbo" sort="Zhu, Wanbo" uniqKey="Zhu W" first="Wanbo" last="Zhu">Wanbo Zhu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Xie, Kai" sort="Xie, Kai" uniqKey="Xie K" first="Kai" last="Xie">Kai Xie</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Lu, Hui" sort="Lu, Hui" uniqKey="Lu H" first="Hui" last="Lu">Hui Lu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Xu, Lei" sort="Xu, Lei" uniqKey="Xu L" first="Lei" last="Xu">Lei Xu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhou, Shusheng" sort="Zhou, Shusheng" uniqKey="Zhou S" first="Shusheng" last="Zhou">Shusheng Zhou</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Fang, Shiyuan" sort="Fang, Shiyuan" uniqKey="Fang S" first="Shiyuan" last="Fang">Shiyuan Fang</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32167181</idno><idno type="pmid">32167181</idno><idno type="doi">10.1002/jmv.25763</idno><idno type="wicri:Area/PubMed/Corpus">000046</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000046</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Initial clinical features of suspected Coronavirus Disease 2019 in two emergency departments outside of Hubei, China.</title><author><name sortKey="Zhu, Wanbo" sort="Zhu, Wanbo" uniqKey="Zhu W" first="Wanbo" last="Zhu">Wanbo Zhu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Xie, Kai" sort="Xie, Kai" uniqKey="Xie K" first="Kai" last="Xie">Kai Xie</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Lu, Hui" sort="Lu, Hui" uniqKey="Lu H" first="Hui" last="Lu">Hui Lu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Xu, Lei" sort="Xu, Lei" uniqKey="Xu L" first="Lei" last="Xu">Lei Xu</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhou, Shusheng" sort="Zhou, Shusheng" uniqKey="Zhou S" first="Shusheng" last="Zhou">Shusheng Zhou</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author><author><name sortKey="Fang, Shiyuan" sort="Fang, Shiyuan" uniqKey="Fang S" first="Shiyuan" last="Fang">Shiyuan Fang</name><affiliation><nlm:affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of medical virology</title><idno type="eISSN">1096-9071</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">With an increasing number of Coronavirus Disease 2019 (COVID-19) cases outside of Hubei, emergency departments (EDs) and fever clinics are facing challenges posed by the large number of admissions of patients suspected to have COVID-19. Therefore, it is of crucial importance to study the initial clinical features of patients, to better differentiate between infected and uninfected patients outside Hubei.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32167181</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1096-9071</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>13</Day></PubDate></JournalIssue><Title>Journal of medical virology</Title><ISOAbbreviation>J. Med. Virol.</ISOAbbreviation></Journal><ArticleTitle>Initial clinical features of suspected Coronavirus Disease 2019 in two emergency departments outside of Hubei, China.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1002/jmv.25763</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">With an increasing number of Coronavirus Disease 2019 (COVID-19) cases outside of Hubei, emergency departments (EDs) and fever clinics are facing challenges posed by the large number of admissions of patients suspected to have COVID-19. Therefore, it is of crucial importance to study the initial clinical features of patients, to better differentiate between infected and uninfected patients outside Hubei.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A total of 116 patients suspected of having COVID-19 who presented to two emergency departments in Anhui for the first time between 24 January 2020 and 20 February 2020 were enrolled in the study. The initial clinical data of these patients, such as epidemiological features, symptoms, laboratory results, and chest computed tomography findings were collected using a standard case report form on admission.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Thirty-two patients were diagnosed with COVID-19; the remaining 84 patients were referred to as negative cases. The median age of the diagnosed patients was 46 years, but only 35 years for negative cases. History of exposure to Wuhan or COVID-19 patients in the previous 2 weeks was observed in 63% of the diagnosed and 44% of negative cases. Median time from illness onset to ED admission was 5 days for all patients, diagnosed patients, and negative cases, respectively. Fever was observed in 27 (84%) and 57 (68%) diagnosed and negative cases, respectively. Nineteen (59%) diagnosed and 24 (29%) negative cases had lymphopenia on admission in ED. A chest CT scan on admission revealed the presence of pneumonia in the majority of the diagnosed patients (30 out of 32, 94%) and in 56 (67%) negative cases. Bilateral involvement and ground-glass opacity (GGO) were present in 91% and 47% of the diagnosed patients.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The initial clinical features of patients suspected of having COVID-19 in EDs outside Hubei were relatively mild. Meanwhile, diagnosed patients without definite exposure history tend to show more atypical initial clinical features in ED. No initial clinical feature was found to be specific to diagnosed patients, which could allow for early clinical diagnosis of COVID-19 in EDs. We recommend strict medical observation and quarantine of all patients suspected of having COVID-19, either in the ED itself or in a dedicated quarantine facility, irrespective of initial clinical features, especially in under-resourced regions without access to rapid nucleic acid amplification tests. This article is protected by copyright. All rights reserved.</AbstractText><CopyrightInformation>This article is protected by copyright. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Wanbo</ForeName><Initials>W</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-3457-3432</Identifier><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of emergency, Affiliated Anhui Provincial Hospital of Anhui Medical University, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xie</LastName><ForeName>Kai</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Hui</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of nursing, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Shusheng</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of ICU, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fang</LastName><ForeName>Shiyuan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of emergency, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of emergency, Affiliated Anhui Provincial Hospital of Anhui Medical University, Hefei, 230001, People's Republic of China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Med Virol</MedlineTA><NlmUniqueID>7705876</NlmUniqueID><ISSNLinking>0146-6615</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">Epidemiology</Keyword><Keyword MajorTopicYN="N">Infection</Keyword><Keyword MajorTopicYN="N">Virus classification</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32167181</ArticleId><ArticleId IdType="doi">10.1002/jmv.25763</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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