[Schonlein-Henoch purpura associated with hepatitis B in a patient with HIV infection].
Identifieur interne : 000713 ( PubMed/Checkpoint ); précédent : 000712; suivant : 000714[Schonlein-Henoch purpura associated with hepatitis B in a patient with HIV infection].
Auteurs : S. Braun [Allemagne] ; J. Ramaker ; E. Dippel ; C C ZouboulisSource :
- Deutsche medizinische Wochenschrift (1946) [ 0012-0472 ] ; 2001.
Descripteurs français
- KwdFr :
- Adulte, Antiviraux (usage thérapeutique), Association de médicaments, Humains, Hépatite B (), Hépatite B (traitement médicamenteux), Infections bactériennes (), Infections à VIH (), Infections à VIH (sang), Interféron de type I (usage thérapeutique), Mâle, Protéines recombinantes, Purpura de Schönlein-Henoch (), Purpura de Schönlein-Henoch (diagnostic), Zidovudine (usage thérapeutique), Études de suivi.
- MESH :
- diagnostic : Purpura de Schönlein-Henoch.
- sang : Infections à VIH.
- traitement médicamenteux : Hépatite B.
- usage thérapeutique : Antiviraux, Interféron de type I, Zidovudine.
- Adulte, Association de médicaments, Humains, Hépatite B, Infections bactériennes, Infections à VIH, Mâle, Protéines recombinantes, Purpura de Schönlein-Henoch, Études de suivi.
English descriptors
- KwdEn :
- Adult, Antiviral Agents (therapeutic use), Bacterial Infections (complications), Drug Therapy, Combination, Follow-Up Studies, HIV Infections (blood), HIV Infections (complications), Hepatitis B (complications), Hepatitis B (drug therapy), Humans, Interferon Type I (therapeutic use), Male, Purpura, Schoenlein-Henoch (complications), Purpura, Schoenlein-Henoch (diagnosis), Recombinant Proteins, Zidovudine (therapeutic use).
- MESH :
- chemical , therapeutic use : Antiviral Agents, Interferon Type I, Zidovudine.
- blood : HIV Infections.
- complications : Bacterial Infections, HIV Infections, Hepatitis B, Purpura, Schoenlein-Henoch.
- diagnosis : Purpura, Schoenlein-Henoch.
- drug therapy : Hepatitis B.
- Adult, Drug Therapy, Combination, Follow-Up Studies, Humans, Male, Recombinant Proteins.
Abstract
A 23-year-old man with HIV-infection and recently diagnosed hepatitis B infection developed painful swelling and palpable purpura in the limbs. In addition, relapsing diarrhoea, arthralgia and pain at the level of the right kidney were noted. The liver, the palpable lymph nodes and the tonsils were enlarged.
DOI: 10.1055/s-2001-10866
PubMed: 11225384
Affiliations:
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pubmed:11225384Le document en format XML
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Dippel</name></author><author><name sortKey="Zouboulis, C C" sort="Zouboulis, C C" uniqKey="Zouboulis C" first="C C" last="Zouboulis">C C Zouboulis</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2001">2001</date><idno type="RBID">pubmed:11225384</idno><idno type="pmid">11225384</idno><idno type="doi">10.1055/s-2001-10866</idno><idno type="wicri:Area/PubMed/Corpus">000725</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000725</idno><idno type="wicri:Area/PubMed/Curation">000725</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000725</idno><idno type="wicri:Area/PubMed/Checkpoint">000713</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000713</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Schonlein-Henoch purpura associated with hepatitis B in a patient with HIV infection].</title><author><name sortKey="Braun, S" sort="Braun, S" uniqKey="Braun S" first="S" last="Braun">S. Braun</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin.</nlm:affiliation><country>Allemagne</country><placeName><settlement type="city">Berlin</settlement><region type="land" nuts="2">Berlin</region></placeName><wicri:orgArea>Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin</wicri:orgArea></affiliation></author><author><name sortKey="Ramaker, J" sort="Ramaker, J" uniqKey="Ramaker J" first="J" last="Ramaker">J. Ramaker</name></author><author><name sortKey="Dippel, E" sort="Dippel, E" uniqKey="Dippel E" first="E" last="Dippel">E. Dippel</name></author><author><name sortKey="Zouboulis, C C" sort="Zouboulis, C C" uniqKey="Zouboulis C" first="C C" last="Zouboulis">C C Zouboulis</name></author></analytic><series><title level="j">Deutsche medizinische Wochenschrift (1946)</title><idno type="ISSN">0012-0472</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antiviral Agents (therapeutic use)</term><term>Bacterial Infections (complications)</term><term>Drug Therapy, Combination</term><term>Follow-Up Studies</term><term>HIV Infections (blood)</term><term>HIV Infections (complications)</term><term>Hepatitis B (complications)</term><term>Hepatitis B (drug therapy)</term><term>Humans</term><term>Interferon Type I (therapeutic use)</term><term>Male</term><term>Purpura, Schoenlein-Henoch (complications)</term><term>Purpura, Schoenlein-Henoch (diagnosis)</term><term>Recombinant Proteins</term><term>Zidovudine (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Antiviraux (usage thérapeutique)</term><term>Association de médicaments</term><term>Humains</term><term>Hépatite B ()</term><term>Hépatite B (traitement médicamenteux)</term><term>Infections bactériennes ()</term><term>Infections à VIH ()</term><term>Infections à VIH (sang)</term><term>Interféron de type I (usage thérapeutique)</term><term>Mâle</term><term>Protéines recombinantes</term><term>Purpura de Schönlein-Henoch ()</term><term>Purpura de Schönlein-Henoch (diagnostic)</term><term>Zidovudine (usage thérapeutique)</term><term>Études de suivi</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Interferon Type I</term><term>Zidovudine</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Bacterial Infections</term><term>HIV Infections</term><term>Hepatitis B</term><term>Purpura, Schoenlein-Henoch</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Purpura, Schoenlein-Henoch</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Purpura de Schönlein-Henoch</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hepatitis B</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Hépatite B</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Interféron de type I</term><term>Zidovudine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Drug Therapy, Combination</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Recombinant Proteins</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Association de médicaments</term><term>Humains</term><term>Hépatite B</term><term>Infections bactériennes</term><term>Infections à VIH</term><term>Mâle</term><term>Protéines recombinantes</term><term>Purpura de Schönlein-Henoch</term><term>Études de suivi</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 23-year-old man with HIV-infection and recently diagnosed hepatitis B infection developed painful swelling and palpable purpura in the limbs. In addition, relapsing diarrhoea, arthralgia and pain at the level of the right kidney were noted. The liver, the palpable lymph nodes and the tonsils were enlarged.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11225384</PMID><DateCompleted><Year>2001</Year><Month>03</Month><Day>08</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0012-0472</ISSN><JournalIssue CitedMedium="Print"><Volume>126</Volume><Issue>5</Issue><PubDate><Year>2001</Year><Month>Feb</Month><Day>02</Day></PubDate></JournalIssue><Title>Deutsche medizinische Wochenschrift (1946)</Title><ISOAbbreviation>Dtsch. Med. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Schonlein-Henoch purpura associated with hepatitis B in a patient with HIV infection].</ArticleTitle><Pagination><MedlinePgn>103-7</MedlinePgn></Pagination><Abstract><AbstractText Label="HISTORY AND CLINICAL FINDINGS" NlmCategory="METHODS">A 23-year-old man with HIV-infection and recently diagnosed hepatitis B infection developed painful swelling and palpable purpura in the limbs. In addition, relapsing diarrhoea, arthralgia and pain at the level of the right kidney were noted. The liver, the palpable lymph nodes and the tonsils were enlarged.</AbstractText><AbstractText Label="INVESTIGATIONS" NlmCategory="METHODS">The following laboratory parameters were abnormal: sedimentation rate 64/70 mmHg, CD4+ cells 462/ml, CD4/CD8 ratio 0.3, serum CRP 16 mg/l, antistreptolysin titre 542 kU/l, complement C3 < 0.1 g/l, GPT 37 U/l, albumin 49.5% and gamma-globulin 28.5%, in urine, leukocytes 25/microliter and protein 0.25 g/l. Hepatitis serology: anti-HBc, HBs-Ag and HBe-Ag positive, anti-HBs and anti-HBe negative, hepatitis A-Ab (IgG) positive, hepatitis A-Ab (IgM) negative, hepatitis C-Ab negative. Pharyngial swab: beta-haemolytic streptococci of group A. Stool examination: amoeba cysts, corona virus and fungi 10(4)-10(5)/ml (control specimen negative). Abdominal sonography showed minor hepatomegaly, splenomegaly and two 0.8 cm-large lymph nodes near the liver entrance. The histology of a skin lesion revealed a florid leukocytoclastic vasculitis at the upper and middle dermal vessels. The immunohistological examination detected IgA, IgM and C3 deposits.</AbstractText><AbstractText Label="TREATMENT AND COURSE" NlmCategory="METHODS">The multiple bacterial infections had initially been considered as triggering the Schönlein-Henoch purpura. However despite successful treatment of these infections severe relapses of both the skin lesions and the systemic manifestations occurred. A drug reaction, autoimmune diseases and tumours were excluded. Only after treatment of hepatitis B infection with recombinant interferon alpha together with administration of zidovudine (treatment of choice at that time) the lesions quickly disappeared without further relapses. During the 5-year-follow-up, recurrent bacterial infections did not induce relapses of the disease, whereas the hepatitis B infection was seroconverted.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">It is likely that the hepatitis B may have been the trigger for the Schönlein-Hennoch-purpura.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Braun</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ramaker</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Dippel</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Zouboulis</LastName><ForeName>C C</ForeName><Initials>CC</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Purpura Schönlein-Henoch assoziiert mit Hepatitis-B-Infektion bei einem HIV-Patienten.</VernacularTitle></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Dtsch Med Wochenschr</MedlineTA><NlmUniqueID>0006723</NlmUniqueID><ISSNLinking>0012-0472</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007370">Interferon Type I</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011994">Recombinant Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>4B9XT59T7S</RegistryNumber><NameOfSubstance UI="D015215">Zidovudine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001424" MajorTopicYN="N">Bacterial Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004359" MajorTopicYN="N">Drug Therapy, Combination</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006509" MajorTopicYN="N">Hepatitis B</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007370" MajorTopicYN="N">Interferon Type I</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011695" MajorTopicYN="N">Purpura, Schoenlein-Henoch</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011994" MajorTopicYN="N">Recombinant Proteins</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015215" MajorTopicYN="N">Zidovudine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading></MeshHeadingList><NumberOfReferences>37</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>2</Month><Day>28</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>3</Month><Day>10</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>2</Month><Day>28</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11225384</ArticleId><ArticleId IdType="doi">10.1055/s-2001-10866</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>Berlin</li></region><settlement><li>Berlin</li></settlement></list><tree><noCountry><name sortKey="Dippel, E" sort="Dippel, E" uniqKey="Dippel E" first="E" last="Dippel">E. Dippel</name><name sortKey="Ramaker, J" sort="Ramaker, J" uniqKey="Ramaker J" first="J" last="Ramaker">J. Ramaker</name><name sortKey="Zouboulis, C C" sort="Zouboulis, C C" uniqKey="Zouboulis C" first="C C" last="Zouboulis">C C Zouboulis</name></noCountry><country name="Allemagne"><region name="Berlin"><name sortKey="Braun, S" sort="Braun, S" uniqKey="Braun S" first="S" last="Braun">S. Braun</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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