CovidV1, PubMed, Checkpoint, bibRecord, 000146

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application.

Identifieur interne : 000146 ( PubMed/Checkpoint ); précédent : 000145; suivant : 000147

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application.

Auteurs : Stephen A. Lauer ; Kyra H. Grantz ; Qifang Bi ; Forrest K. Jones ; Qulu Zheng ; Hannah R. Meredith ; Andrew S. Azman ; Nicholas G. Reich [États-Unis] ; Justin Lessler

Source :

Annals of internal medicine [ 1539-3704 ] ; 2020.

RBID : pubmed:32150748

Abstract

A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities.

DOI: 10.7326/M20-0504
PubMed: 32150748

Affiliations:

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<front><div type="abstract" xml:lang="en">A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities.</div>
</front>
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<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32150748</PMID>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>09</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1539-3704</ISSN>
<JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year>
<Month>Mar</Month>
<Day>10</Day>
</PubDate>
</JournalIssue>
<Title>Annals of internal medicine</Title>
<ISOAbbreviation>Ann. Intern. Med.</ISOAbbreviation>
</Journal>
<ArticleTitle>The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application.</ArticleTitle>
<ELocationID EIdType="doi" ValidYN="Y">10.7326/M20-0504</ELocationID>
<Abstract><AbstractText Label="Background" NlmCategory="UNASSIGNED">A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities.</AbstractText>
<AbstractText Label="Objective" NlmCategory="UNASSIGNED">To estimate the length of the incubation period of COVID-19 and describe its public health implications.</AbstractText>
<AbstractText Label="Design" NlmCategory="UNASSIGNED">Pooled analysis of confirmed COVID-19 cases reported between 4 January 2020 and 24 February 2020.</AbstractText>
<AbstractText Label="Setting" NlmCategory="UNASSIGNED">News reports and press releases from 50 provinces, regions, and countries outside Wuhan, Hubei province, China.</AbstractText>
<AbstractText Label="Participants" NlmCategory="UNASSIGNED">Persons with confirmed SARS-CoV-2 infection outside Hubei province, China.</AbstractText>
<AbstractText Label="Measurements" NlmCategory="UNASSIGNED">Patient demographic characteristics and dates and times of possible exposure, symptom onset, fever onset, and hospitalization.</AbstractText>
<AbstractText Label="Results" NlmCategory="UNASSIGNED">There were 181 confirmed cases with identifiable exposure and symptom onset windows to estimate the incubation period of COVID-19. The median incubation period was estimated to be 5.1 days (95% CI, 4.5 to 5.8 days), and 97.5% of those who develop symptoms will do so within 11.5 days (CI, 8.2 to 15.6 days) of infection. These estimates imply that, under conservative assumptions, 101 out of every 10 000 cases (99th percentile, 482) will develop symptoms after 14 days of active monitoring or quarantine.</AbstractText>
<AbstractText Label="Limitation" NlmCategory="UNASSIGNED">Publicly reported cases may overrepresent severe cases, the incubation period for which may differ from that of mild cases.</AbstractText>
<AbstractText Label="Conclusion" NlmCategory="UNASSIGNED">This work provides additional evidence for a median incubation period for COVID-19 of approximately 5 days, similar to SARS. Our results support current proposals for the length of quarantine or active monitoring of persons potentially exposed to SARS-CoV-2, although longer monitoring periods might be justified in extreme cases.</AbstractText>
<AbstractText Label="Primary Funding Source" NlmCategory="UNASSIGNED">U.S. Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, and Alexander von Humboldt Foundation.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lauer</LastName>
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<Initials>SA</Initials>
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<Author ValidYN="Y"><LastName>Grantz</LastName>
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<Author ValidYN="Y"><LastName>Meredith</LastName>
<ForeName>Hannah R</ForeName>
<Initials>HR</Initials>
<AffiliationInfo><Affiliation>Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (S.A.L., K.H.G., Q.B., F.K.J., Q.Z., H.R.M., A.S.A., J.L.).</Affiliation>
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<Initials>AS</Initials>
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<AffiliationInfo><Affiliation>School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, and Ludwig-Maximilians-Universität, Munich, Germany (N.G.R.).</Affiliation>
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<Initials>J</Initials>
<AffiliationInfo><Affiliation>Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (S.A.L., K.H.G., Q.B., F.K.J., Q.Z., H.R.M., A.S.A., J.L.).</Affiliation>
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The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application.

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application.

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