[Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies].
Identifieur interne : 000090 ( PubMed/Checkpoint ); précédent : 000089; suivant : 000091[Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies].
Auteurs : C. Chen [République populaire de Chine] ; X R Zhang [République populaire de Chine] ; Z Y Ju [République populaire de Chine] ; W F He [République populaire de Chine]Source :
- Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns [ 1009-2587 ] ; 2020.
Abstract
Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of patients and social stability. In the later stage of disease, some COVID-19 patients may develop into acute respiratory distress syndrome or even multiple organ failure. However, one of the most important mechanism underlying the deterioration of disease is cytokine storm. At present, some therapies such as interleukin-6 antibody blocker, stem cell therapy, and transfusion of convalescent plasma have been applied to counteract the cytokine storm and have made some progress. This article reviews the influences of cytokine storm syndrome on the COVID-19 and the corresponding immunotherapies to resist cytokine storm.
DOI: 10.3760/cma.j.cn501120-20200224-00088
PubMed: 32114747
Affiliations:
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Chen</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, X R" sort="Zhang, X R" uniqKey="Zhang X" first="X R" last="Zhang">X R Zhang</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author><author><name sortKey="Ju, Z Y" sort="Ju, Z Y" uniqKey="Ju Z" first="Z Y" last="Ju">Z Y Ju</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="He, W F" sort="He, W F" uniqKey="He W" first="W F" last="He">W F He</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32114747</idno><idno type="pmid">32114747</idno><idno type="doi">10.3760/cma.j.cn501120-20200224-00088</idno><idno type="wicri:Area/PubMed/Corpus">000370</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000370</idno><idno type="wicri:Area/PubMed/Curation">000370</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000370</idno><idno type="wicri:Area/PubMed/Checkpoint">000090</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000090</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies].</title><author><name sortKey="Chen, C" sort="Chen, C" uniqKey="Chen C" first="C" last="Chen">C. Chen</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, X R" sort="Zhang, X R" uniqKey="Zhang X" first="X R" last="Zhang">X R Zhang</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author><author><name sortKey="Ju, Z Y" sort="Ju, Z Y" uniqKey="Ju Z" first="Z Y" last="Ju">Z Y Ju</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="He, W F" sort="He, W F" uniqKey="He W" first="W F" last="He">W F He</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038</wicri:regionArea><wicri:noRegion>Chongqing 400038</wicri:noRegion></affiliation></author></analytic><series><title level="j">Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns</title><idno type="ISSN">1009-2587</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of patients and social stability. In the later stage of disease, some COVID-19 patients may develop into acute respiratory distress syndrome or even multiple organ failure. However, one of the most important mechanism underlying the deterioration of disease is cytokine storm. At present, some therapies such as interleukin-6 antibody blocker, stem cell therapy, and transfusion of convalescent plasma have been applied to counteract the cytokine storm and have made some progress. This article reviews the influences of cytokine storm syndrome on the COVID-19 and the corresponding immunotherapies to resist cytokine storm.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32114747</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1009-2587</ISSN><JournalIssue CitedMedium="Print"><Volume>36</Volume><Issue>0</Issue><PubDate><Year>2020</Year><Month>Mar</Month><Day>01</Day></PubDate></JournalIssue><Title>Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns</Title><ISOAbbreviation>Zhonghua Shao Shang Za Zhi</ISOAbbreviation></Journal><ArticleTitle>[Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies].</ArticleTitle><Pagination><MedlinePgn>E005</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3760/cma.j.cn501120-20200224-00088</ELocationID><Abstract><AbstractText>Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of patients and social stability. In the later stage of disease, some COVID-19 patients may develop into acute respiratory distress syndrome or even multiple organ failure. However, one of the most important mechanism underlying the deterioration of disease is cytokine storm. At present, some therapies such as interleukin-6 antibody blocker, stem cell therapy, and transfusion of convalescent plasma have been applied to counteract the cytokine storm and have made some progress. This article reviews the influences of cytokine storm syndrome on the COVID-19 and the corresponding immunotherapies to resist cytokine storm.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>X R</ForeName><Initials>XR</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ju</LastName><ForeName>Z Y</ForeName><Initials>ZY</Initials><AffiliationInfo><Affiliation>Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>He</LastName><ForeName>W F</ForeName><Initials>WF</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>chi</Language><GrantList CompleteYN="Y"><Grant><GrantID>31872742</GrantID><Agency>General Program of National Natural Science Foundation of China</Agency><Country></Country></Grant><Grant><GrantID>20QNPY024</GrantID><Agency>Military Medical Science and Technology Youth Cultivation Plan</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Zhonghua Shao Shang Za Zhi</MedlineTA><NlmUniqueID>100959418</NlmUniqueID><ISSNLinking>1009-2587</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><OtherAbstract Type="Publisher" Language="chi"><AbstractText>新型冠状病毒肺炎（COVID-19）已严重影响了患者的生命安全和社会稳定。部分COVID-19患者在疾病后期可发展为急性呼吸窘迫综合征、甚至多器官功能衰竭，而导致这一病情转变潜在的重要机制就是细胞因子风暴的产生。目前，白细胞介素6抗体阻断剂、干细胞疗法和回输康复患者血清等方法缓解细胞因子风暴已取得一定进展。本文就细胞因子风暴对COVID-19的影响及抵抗细胞因子风暴的免疫治疗方法进行综述。.</AbstractText></OtherAbstract><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Corona Virus Disease 2019</Keyword><Keyword MajorTopicYN="N">Cytokine storm</Keyword><Keyword MajorTopicYN="N">Cytokines</Keyword><Keyword MajorTopicYN="N">Immune system</Keyword><Keyword MajorTopicYN="N">Immunotherapy</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32114747</ArticleId><ArticleId IdType="doi">10.3760/cma.j.cn501120-20200224-00088</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Guangdong</li></region><settlement><li>Jiangmen</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, C" sort="Chen, C" uniqKey="Chen C" first="C" last="Chen">C. Chen</name></noRegion><name sortKey="He, W F" sort="He, W F" uniqKey="He W" first="W F" last="He">W F He</name><name sortKey="Ju, Z Y" sort="Ju, Z Y" uniqKey="Ju Z" first="Z Y" last="Ju">Z Y Ju</name><name sortKey="Zhang, X R" sort="Zhang, X R" uniqKey="Zhang X" first="X R" last="Zhang">X R Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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