Middle East respiratory syndrome coronavirus: review of the current situation in the world
Identifieur interne : 000174 ( Pmc/Curation ); précédent : 000173; suivant : 000175Middle East respiratory syndrome coronavirus: review of the current situation in the world
Auteurs : Michael Shapiro [Israël] ; Beny London [Israël] ; Daniel Nigri [Israël] ; Alon Shoss [Israël] ; Eyal Zilber [Israël] ; Itay Fogel [Israël]Source :
- Disaster and Military Medicine [ 2054-314X ] ; 2016.
Abstract
This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countries, mostly in Saudi Arabia and the Middle East. The epidemiology of the infection is compatible with multiple introductions of the virus into humans from an animal reservoir, probably dromedary camels. The clinical presentation ranges from no symptoms to severe pneumonitis and respiratory failure. Most confirmed cases so far were part of MERS-CoV clusters in hospital settings, affecting mainly middle-aged men and patients with a chronic disease or immuno-suppressed status. There is no vaccine or anti-viral medication available. Viral epidemics can occur anywhere in today’s “global village”. MERS-CoV is a relatively new virus, and this work is intended to add to the still-sparse data on its epidemiology, modes of transmission, natural history, and clinical features as well as to describe the preparedness plan for MERS-CoV infection in several countries. Effective national and international preparedness plans are essential to predict and control outbreaks, improve patient management, and ensure global health security.
Url:
DOI: 10.1186/s40696-016-0019-2
PubMed: 28265443
PubMed Central: 5329956
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<front><div type="abstract" xml:lang="en"><p>This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countries, mostly in Saudi Arabia and the Middle East. The epidemiology of the infection is compatible with multiple introductions of the virus into humans from an animal reservoir, probably dromedary camels. The clinical presentation ranges from no symptoms to severe pneumonitis and respiratory failure. Most confirmed cases so far were part of MERS-CoV clusters in hospital settings, affecting mainly middle-aged men and patients with a chronic disease or immuno-suppressed status. There is no vaccine or anti-viral medication available. Viral epidemics can occur anywhere in today’s “global village”. MERS-CoV is a relatively new virus, and this work is intended to add to the still-sparse data on its epidemiology, modes of transmission, natural history, and clinical features as well as to describe the preparedness plan for MERS-CoV infection in several countries. Effective national and international preparedness plans are essential to predict and control outbreaks, improve patient management, and ensure global health security.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Disaster Mil Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Disaster Mil Med</journal-id>
<journal-title-group><journal-title>Disaster and Military Medicine</journal-title>
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<issn pub-type="epub">2054-314X</issn>
<publisher><publisher-name>BioMed Central</publisher-name>
<publisher-loc>London</publisher-loc>
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<article-id pub-id-type="publisher-id">19</article-id>
<article-id pub-id-type="doi">10.1186/s40696-016-0019-2</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review</subject>
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<title-group><article-title>Middle East respiratory syndrome coronavirus: review of the current situation in the world</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Shapiro</surname>
<given-names>Michael</given-names>
</name>
<address><email>mikehpg@gmail.com</email>
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<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>London</surname>
<given-names>Beny</given-names>
</name>
<address><email>benylondon@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nigri</surname>
<given-names>Daniel</given-names>
</name>
<address><email>nigri.daniel@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shoss</surname>
<given-names>Alon</given-names>
</name>
<address><email>alon.shoss@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zilber</surname>
<given-names>Eyal</given-names>
</name>
<address><email>zilbereyal@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Fogel</surname>
<given-names>Itay</given-names>
</name>
<address><phone>+972-52-945-35-87</phone>
<email>fogelitay@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff2">2</xref>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<aff id="Aff1"><label>1</label>
IDF Medical Corps Training School, City of Training Bases, Israel</aff>
<aff id="Aff2"><label>2</label>
IDF Medical Corps, Surgeon General Headquarters, Tel Hashomer, Israel</aff>
<aff id="Aff3"><label>3</label>
Department of Pediatrics C, Schneider Children’s Medical Center of Israel, Petach Tikva, 49202 Israel</aff>
</contrib-group>
<pub-date pub-type="epub"><day>4</day>
<month>5</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>4</day>
<month>5</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="collection"><year>2016</year>
</pub-date>
<volume>2</volume>
<elocation-id>9</elocation-id>
<history><date date-type="received"><day>12</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>26</day>
<month>4</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>© Shapiro et al. 2016</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
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<abstract id="Abs1"><p>This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countries, mostly in Saudi Arabia and the Middle East. The epidemiology of the infection is compatible with multiple introductions of the virus into humans from an animal reservoir, probably dromedary camels. The clinical presentation ranges from no symptoms to severe pneumonitis and respiratory failure. Most confirmed cases so far were part of MERS-CoV clusters in hospital settings, affecting mainly middle-aged men and patients with a chronic disease or immuno-suppressed status. There is no vaccine or anti-viral medication available. Viral epidemics can occur anywhere in today’s “global village”. MERS-CoV is a relatively new virus, and this work is intended to add to the still-sparse data on its epidemiology, modes of transmission, natural history, and clinical features as well as to describe the preparedness plan for MERS-CoV infection in several countries. Effective national and international preparedness plans are essential to predict and control outbreaks, improve patient management, and ensure global health security.</p>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>MERS-CoV</kwd>
<kwd>Coronavirus</kwd>
<kwd>Unusual biological event</kwd>
<kwd>Outbreaks</kwd>
<kwd>Emerging diseases</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© The Author(s) 2016</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
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