CovidV1, Pmc, Corpus, bibRecord, 000361

Arenavirus Reverse Genetics: New Approaches for the Investigation of Arenavirus Biology and Development of Antiviral Strategies

Identifieur interne : 000361 ( Pmc/Corpus ); précédent : 000360; suivant : 000362

Arenavirus Reverse Genetics: New Approaches for the Investigation of Arenavirus Biology and Development of Antiviral Strategies

Auteurs : Sebastien E. Emonet ; Shuzo Urata ; Juan C. De La Torre

Source :

Virology [ 0042-6822 ] ; 2011.

RBID : PMC:3057228

Abstract

Several arenaviruses, chiefly Lassa virus, cause hemorrhagic fever disease in humans and pose a significant public health problem in their endemic regions. On the other hand the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions and associated disease. The development of novel antiviral strategies to combat pathogenic arenaviruses would be facilitated by a detailed understanding of the arenavirus molecular and cell biology. To this end, the development of reverse genetics systems for several arenaviruses has provided investigators with novel and powerful approaches to dissect the functions of arenavirus proteins and their interactions with host factors required to complete each of the steps of the virus life cycle, as well as to cause disease.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057228

DOI: 10.1016/j.virol.2011.01.013
PubMed: 21324503
PubMed Central: 3057228

Links to Exploration step

PMC:3057228

Le document en format XML

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<author><name sortKey="Emonet, Sebastien E" sort="Emonet, Sebastien E" uniqKey="Emonet S" first="Sebastien E." last="Emonet">Sebastien E. Emonet</name>
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<author><name sortKey="Urata, Shuzo" sort="Urata, Shuzo" uniqKey="Urata S" first="Shuzo" last="Urata">Shuzo Urata</name>
</author>
<author><name sortKey="De La Torre, Juan C" sort="De La Torre, Juan C" uniqKey="De La Torre J" first="Juan C." last="De La Torre">Juan C. De La Torre</name>
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<author><name sortKey="Urata, Shuzo" sort="Urata, Shuzo" uniqKey="Urata S" first="Shuzo" last="Urata">Shuzo Urata</name>
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<author><name sortKey="De La Torre, Juan C" sort="De La Torre, Juan C" uniqKey="De La Torre J" first="Juan C." last="De La Torre">Juan C. De La Torre</name>
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<series><title level="j">Virology</title>
<idno type="ISSN">0042-6822</idno>
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<front><div type="abstract" xml:lang="en"><p id="P2">Several arenaviruses, chiefly Lassa virus, cause hemorrhagic fever disease in humans and pose a significant public health problem in their endemic regions. On the other hand the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions and associated disease. The development of novel antiviral strategies to combat pathogenic arenaviruses would be facilitated by a detailed understanding of the arenavirus molecular and cell biology. To this end, the development of reverse genetics systems for several arenaviruses has provided investigators with novel and powerful approaches to dissect the functions of arenavirus proteins and their interactions with host factors required to complete each of the steps of the virus life cycle, as well as to cause disease.</p>
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<pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <pmc-dir>properties manuscript</pmc-dir>
  <front><journal-meta><journal-id journal-id-type="nlm-journal-id">0110674</journal-id>
<journal-id journal-id-type="pubmed-jr-id">8015</journal-id>
<journal-id journal-id-type="nlm-ta">Virology</journal-id>
<journal-title>Virology</journal-title>
<issn pub-type="ppub">0042-6822</issn>
<issn pub-type="epub">1096-0341</issn>
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<article-id pub-id-type="manuscript">NIHMS268470</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>Arenavirus Reverse Genetics: New Approaches for the Investigation of Arenavirus Biology and Development of Antiviral Strategies</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Emonet</surname>
<given-names>Sebastien E.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Urata</surname>
<given-names>Shuzo</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>de la Torre</surname>
<given-names>Juan C.</given-names>
</name>
</contrib>
<aff id="A1">Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 USA</aff>
</contrib-group>
<author-notes><fn id="FN1" fn-type="equal"><p id="P1">All authors equally contributed to the preparation of this minireview.</p>
</fn>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>22</day>
<month>2</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>15</day>
<month>2</month>
<year>2011</year>
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<pub-date pub-type="ppub"><day>15</day>
<month>3</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>15</day>
<month>3</month>
<year>2012</year>
</pub-date>
<volume>411</volume>
<issue>2</issue>
<fpage>416</fpage>
<lpage>425</lpage>
<permissions><copyright-statement>© 2011 Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2011</copyright-year>
</permissions>
<abstract><p id="P2">Several arenaviruses, chiefly Lassa virus, cause hemorrhagic fever disease in humans and pose a significant public health problem in their endemic regions. On the other hand the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions and associated disease. The development of novel antiviral strategies to combat pathogenic arenaviruses would be facilitated by a detailed understanding of the arenavirus molecular and cell biology. To this end, the development of reverse genetics systems for several arenaviruses has provided investigators with novel and powerful approaches to dissect the functions of arenavirus proteins and their interactions with host factors required to complete each of the steps of the virus life cycle, as well as to cause disease.</p>
</abstract>
<contract-num rid="AI1">R01 AI079665-02
				||AI</contract-num>
<contract-num rid="AI1">R01 AI077719-02
				||AI</contract-num>
<contract-num rid="AI1">R01 AI047140-07
				||AI</contract-num>
<contract-sponsor id="AI1">National Institute of Allergy and Infectious Diseases Extramural Activities  : NIAID</contract-sponsor>
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</front>
</pmc>
</record>

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Arenavirus Reverse Genetics: New Approaches for the Investigation of Arenavirus Biology and Development of Antiviral Strategies

Arenavirus Reverse Genetics: New Approaches for the Investigation of Arenavirus Biology and Development of Antiviral Strategies

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki