Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats
Identifieur interne : 000244 ( Pmc/Checkpoint ); précédent : 000243; suivant : 000245Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats
Auteurs : F. C. Fragkou ; K. K. Adamama-Moraitou ; T. Poutahidis ; N. N. Prassinos ; M. Kritsepi-Konstantinou ; P. G. Xenoulis ; J. M. Steiner ; J. A. Lidbury ; J. S. Suchodolski ; T. S. RallisSource :
- Journal of Veterinary Internal Medicine [ 0891-6640 ] ; 2016.
Abstract
The term triaditis designates the concurrent presence of idiopathic inflammatory bowel disease (
The histopathology of concurrent, but often subclinical, inflammatory processes in the small intestine, liver, and pancreas of cats is poorly described. We aimed to investigate the frequency of enteritis, cholangitis, pancreatitis, or some combination of these in symptomatic and asymptomatic cats, compare clinicopathological features, and correlate histopathological with laboratory findings.
Domestic cats (27 symptomatic, 20 asymptomatic, and 8 normal).
Prospective study. Physical examination, laboratory variables (
Inflammatory lesions were detected in 47 cats (27 symptomatic, 20 asymptomatic). In total, 20 cats had histopathologic lesions of
Histopathological evidence of
Url:
DOI: 10.1111/jvim.14356
PubMed: 27296565
PubMed Central: 5089651
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:5089651Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats</title><author><name sortKey="Fragkou, F C" sort="Fragkou, F C" uniqKey="Fragkou F" first="F. C." last="Fragkou">F. C. Fragkou</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Adamama Oraitou, K K" sort="Adamama Oraitou, K K" uniqKey="Adamama Oraitou K" first="K. K." last="Adamama-Moraitou">K. K. Adamama-Moraitou</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Poutahidis, T" sort="Poutahidis, T" uniqKey="Poutahidis T" first="T." last="Poutahidis">T. Poutahidis</name><affiliation><nlm:aff id="jvim14356-aff-0002"></nlm:aff></affiliation></author><author><name sortKey="Prassinos, N N" sort="Prassinos, N N" uniqKey="Prassinos N" first="N. N." last="Prassinos">N. N. Prassinos</name><affiliation><nlm:aff id="jvim14356-aff-0003"></nlm:aff></affiliation></author><author><name sortKey="Kritsepi Onstantinou, M" sort="Kritsepi Onstantinou, M" uniqKey="Kritsepi Onstantinou M" first="M." last="Kritsepi-Konstantinou">M. Kritsepi-Konstantinou</name><affiliation><nlm:aff id="jvim14356-aff-0004"></nlm:aff></affiliation></author><author><name sortKey="Xenoulis, P G" sort="Xenoulis, P G" uniqKey="Xenoulis P" first="P. G." last="Xenoulis">P. G. Xenoulis</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation><affiliation><nlm:aff id="jvim14356-curr-0001"></nlm:aff></affiliation><affiliation><nlm:aff id="jvim14356-curr-0002"></nlm:aff></affiliation></author><author><name sortKey="Steiner, J M" sort="Steiner, J M" uniqKey="Steiner J" first="J. M." last="Steiner">J. M. Steiner</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Lidbury, J A" sort="Lidbury, J A" uniqKey="Lidbury J" first="J. A." last="Lidbury">J. A. Lidbury</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Suchodolski, J S" sort="Suchodolski, J S" uniqKey="Suchodolski J" first="J. S." last="Suchodolski">J. S. Suchodolski</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Rallis, T S" sort="Rallis, T S" uniqKey="Rallis T" first="T. S." last="Rallis">T. S. Rallis</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27296565</idno><idno type="pmc">5089651</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089651</idno><idno type="RBID">PMC:5089651</idno><idno type="doi">10.1111/jvim.14356</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000639</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000639</idno><idno type="wicri:Area/Pmc/Curation">000639</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000639</idno><idno type="wicri:Area/Pmc/Checkpoint">000244</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000244</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats</title><author><name sortKey="Fragkou, F C" sort="Fragkou, F C" uniqKey="Fragkou F" first="F. C." last="Fragkou">F. C. Fragkou</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Adamama Oraitou, K K" sort="Adamama Oraitou, K K" uniqKey="Adamama Oraitou K" first="K. K." last="Adamama-Moraitou">K. K. Adamama-Moraitou</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Poutahidis, T" sort="Poutahidis, T" uniqKey="Poutahidis T" first="T." last="Poutahidis">T. Poutahidis</name><affiliation><nlm:aff id="jvim14356-aff-0002"></nlm:aff></affiliation></author><author><name sortKey="Prassinos, N N" sort="Prassinos, N N" uniqKey="Prassinos N" first="N. N." last="Prassinos">N. N. Prassinos</name><affiliation><nlm:aff id="jvim14356-aff-0003"></nlm:aff></affiliation></author><author><name sortKey="Kritsepi Onstantinou, M" sort="Kritsepi Onstantinou, M" uniqKey="Kritsepi Onstantinou M" first="M." last="Kritsepi-Konstantinou">M. Kritsepi-Konstantinou</name><affiliation><nlm:aff id="jvim14356-aff-0004"></nlm:aff></affiliation></author><author><name sortKey="Xenoulis, P G" sort="Xenoulis, P G" uniqKey="Xenoulis P" first="P. G." last="Xenoulis">P. G. Xenoulis</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation><affiliation><nlm:aff id="jvim14356-curr-0001"></nlm:aff></affiliation><affiliation><nlm:aff id="jvim14356-curr-0002"></nlm:aff></affiliation></author><author><name sortKey="Steiner, J M" sort="Steiner, J M" uniqKey="Steiner J" first="J. M." last="Steiner">J. M. Steiner</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Lidbury, J A" sort="Lidbury, J A" uniqKey="Lidbury J" first="J. A." last="Lidbury">J. A. Lidbury</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Suchodolski, J S" sort="Suchodolski, J S" uniqKey="Suchodolski J" first="J. S." last="Suchodolski">J. S. Suchodolski</name><affiliation><nlm:aff id="jvim14356-aff-0005"></nlm:aff></affiliation></author><author><name sortKey="Rallis, T S" sort="Rallis, T S" uniqKey="Rallis T" first="T. S." last="Rallis">T. S. Rallis</name><affiliation><nlm:aff id="jvim14356-aff-0001"></nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Veterinary Internal Medicine</title><idno type="ISSN">0891-6640</idno><idno type="eISSN">1939-1676</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="jvim14356-sec-0001"><title>Background</title><p>The term triaditis designates the concurrent presence of idiopathic inflammatory bowel disease (<styled-content style="fixed-case">IBD</styled-content>), cholangitis, and pancreatitis in cats.</p></sec><sec id="jvim14356-sec-0002"><title>Hypothesis/Objectives</title><p>The histopathology of concurrent, but often subclinical, inflammatory processes in the small intestine, liver, and pancreas of cats is poorly described. We aimed to investigate the frequency of enteritis, cholangitis, pancreatitis, or some combination of these in symptomatic and asymptomatic cats, compare clinicopathological features, and correlate histopathological with laboratory findings.</p></sec><sec id="jvim14356-sec-0003"><title>Animals</title><p>Domestic cats (27 symptomatic, 20 asymptomatic, and 8 normal).</p></sec><sec id="jvim14356-sec-0004"><title>Methods</title><p>Prospective study. Physical examination, laboratory variables (<styled-content style="fixed-case">CBC</styled-content>, serum biochemistry profile, serum thyroxine concentration, serum feline trypsin‐like immunoreactivity [<styled-content style="fixed-case">fTLI</styled-content>], feline lipase immunoreactivity [<styled-content style="fixed-case">fPLI</styled-content>, as measured by Spec <styled-content style="fixed-case">fPL</styled-content><sup>®</sup>], urinalysis, and fecal analysis), imaging, and histopathological examinations were conducted. Feline liver, pancreas, and small intestine were biopsied during laparotomy.</p></sec><sec id="jvim14356-sec-0005"><title>Results</title><p>Inflammatory lesions were detected in 47 cats (27 symptomatic, 20 asymptomatic). In total, 20 cats had histopathologic lesions of <styled-content style="fixed-case">IBD</styled-content> (13/47, 27.7%), cholangitis (6/47, 12.8%), or pancreatitis (1/47, 2.1%) alone, or inflammation involving >1 organ (27/47, 57.4%). More specifically, 16/47 cats (34.0%) had concurrent lesions of <styled-content style="fixed-case">IBD</styled-content> and cholangitis, 3/47 (6.4%) of <styled-content style="fixed-case">IBD</styled-content> and pancreatitis, and 8/47 cats (17%) of triaditis. Triaditis was identified only in symptomatic cats (8/27, 29.6%). A mild, positive correlation was detected between the severity (score) of <styled-content style="fixed-case">IBD</styled-content> lesions and the number of comorbidities (rho = +0.367, <italic>P</italic> = .022).</p></sec><sec id="jvim14356-sec-0006"><title>Conclusions and Clinical Importance</title><p>Histopathological evidence of <styled-content style="fixed-case">IBD</styled-content> or <styled-content style="fixed-case">IBD</styled-content> with comorbidities was detected in both symptomatic and asymptomatic cats. The possibility of triaditis should be considered in symptomatic cats with severe <styled-content style="fixed-case">IBD</styled-content>.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rothuizen, J" uniqKey="Rothuizen J">J Rothuizen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rothuizen, J" uniqKey="Rothuizen J">J Rothuizen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ettinger, Sj" uniqKey="Ettinger S">SJ Ettinger</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ettinger, Sj" uniqKey="Ettinger S">SJ Ettinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="August, Jr" uniqKey="August J">JR August</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ettinger, Sj" uniqKey="Ettinger S">SJ Ettinger</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Bonagura, Jd" uniqKey="Bonagura J">JD Bonagura</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Vet Intern Med</journal-id><journal-id journal-id-type="iso-abbrev">J. Vet. Intern. Med</journal-id><journal-id journal-id-type="doi">10.1111/(ISSN)1939-1676</journal-id><journal-id journal-id-type="publisher-id">JVIM</journal-id><journal-title-group><journal-title>Journal of Veterinary Internal Medicine</journal-title></journal-title-group><issn pub-type="ppub">0891-6640</issn><issn pub-type="epub">1939-1676</issn><publisher><publisher-name>John Wiley and Sons Inc.</publisher-name><publisher-loc>Hoboken</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27296565</article-id><article-id pub-id-type="pmc">5089651</article-id><article-id pub-id-type="doi">10.1111/jvim.14356</article-id><article-id pub-id-type="publisher-id">JVIM14356</article-id><article-categories><subj-group subj-group-type="overline"><subject>Standard Article</subject></subj-group><subj-group subj-group-type="heading"><subject>SMALL ANIMAL</subject><subj-group subj-group-type="heading"><subject>Standard Articles</subject><subj-group subj-group-type="heading"><subject>Hepatology</subject></subj-group></subj-group></subj-group></article-categories><title-group><article-title>Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats</article-title><alt-title alt-title-type="left-running-head">Fragkou et al</alt-title></title-group><contrib-group><contrib id="jvim14356-cr-0001" contrib-type="author" corresp="yes"><name><surname>Fragkou</surname><given-names>F.C.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0001"><sup>1</sup></xref></contrib><contrib id="jvim14356-cr-0002" contrib-type="author"><name><surname>Adamama‐Moraitou</surname><given-names>K.K.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0001"><sup>1</sup></xref></contrib><contrib id="jvim14356-cr-0003" contrib-type="author"><name><surname>Poutahidis</surname><given-names>T.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0002"><sup>2</sup></xref></contrib><contrib id="jvim14356-cr-0004" contrib-type="author"><name><surname>Prassinos</surname><given-names>N.N.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0003"><sup>3</sup></xref></contrib><contrib id="jvim14356-cr-0005" contrib-type="author"><name><surname>Kritsepi‐Konstantinou</surname><given-names>M.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0004"><sup>4</sup></xref></contrib><contrib id="jvim14356-cr-0006" contrib-type="author"><name><surname>Xenoulis</surname><given-names>P.G.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0005"><sup>5</sup></xref><xref ref-type="aff" rid="jvim14356-curr-0001"><sup>6</sup></xref><xref ref-type="aff" rid="jvim14356-curr-0002"><sup>7</sup></xref></contrib><contrib id="jvim14356-cr-0007" contrib-type="author"><name><surname>Steiner</surname><given-names>J.M.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0005"><sup>5</sup></xref></contrib><contrib id="jvim14356-cr-0008" contrib-type="author"><name><surname>Lidbury</surname><given-names>J.A.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0005"><sup>5</sup></xref></contrib><contrib id="jvim14356-cr-0009" contrib-type="author"><name><surname>Suchodolski</surname><given-names>J.S.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0005"><sup>5</sup></xref></contrib><contrib id="jvim14356-cr-0010" contrib-type="author"><name><surname>Rallis</surname><given-names>T.S.</given-names></name><xref ref-type="aff" rid="jvim14356-aff-0001"><sup>1</sup></xref></contrib></contrib-group><aff id="jvim14356-aff-0001"><label><sup>1</sup></label><named-content content-type="organisation-division">Medicine Unit</named-content><named-content content-type="organisation-division">Companion Animal Clinic</named-content><named-content content-type="organisation-division">School of Veterinary Medicine</named-content><named-content content-type="organisation-division">Faculty of Health Sciences</named-content><institution>Aristotle University of Thessaloniki</institution><named-content content-type="city">Thessaloniki</named-content><country country="GR">Greece</country></aff><aff id="jvim14356-aff-0002"><label><sup>2</sup></label><named-content content-type="organisation-division">Laboratory of Pathology</named-content><named-content content-type="organisation-division">School of Veterinary Medicine</named-content><named-content content-type="organisation-division">Faculty of Health Sciences</named-content><institution>Aristotle University of Thessaloniki</institution><named-content content-type="city">Thessaloniki</named-content><country country="GR">Greece</country></aff><aff id="jvim14356-aff-0003"><label><sup>3</sup></label><named-content content-type="organisation-division">Surgery and Obstetrics Unit</named-content><named-content content-type="organisation-division">Companion Animal Clinic</named-content><named-content content-type="organisation-division">School of Veterinary Medicine</named-content><named-content content-type="organisation-division">Faculty of Health Sciences</named-content><institution>Aristotle University of Thessaloniki</institution><named-content content-type="city">Thessaloniki</named-content><country country="GR">Greece</country></aff><aff id="jvim14356-aff-0004"><label><sup>4</sup></label><named-content content-type="organisation-division">Diagnostic Laboratory</named-content><named-content content-type="organisation-division">School of Veterinary Medicine</named-content><named-content content-type="organisation-division">Faculty of Health Sciences</named-content><institution>Aristotle University of Thessaloniki</institution><named-content content-type="city">Thessaloniki</named-content><country country="GR">Greece</country></aff><aff id="jvim14356-aff-0005"><label><sup>5</sup></label><named-content content-type="organisation-division">Gastrointestinal Laboratory</named-content><institution>Texas A&M University</institution><named-content content-type="city">College Station</named-content><named-content content-type="country-part">TX</named-content><country country="US">USA</country></aff><aff id="jvim14356-curr-0001"><label><sup>6</sup></label>Present address:<named-content content-type="organisation-division">Clinic of Medicine</named-content><institution>Faculty of Veterinary Medicine</institution><institution>University of Thessaly</institution><named-content content-type="city">Karditsa</named-content><country country="GR">Greece</country></aff><aff id="jvim14356-curr-0002"><label><sup>7</sup></label>Present address:<institution>Animal Medical Center of Athens</institution><named-content content-type="city">Athens</named-content><country country="GR">Greece</country></aff><author-notes><corresp id="correspondenceTo"><label>*</label>Corresponding author: F. Fragkou, Stavrou Voutira 11str., Medicine Unit, Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54627, Greece; e‐mail: <email>foteinif@hotmail.com</email>.</corresp></author-notes><pub-date pub-type="epub"><day>14</day><month>6</month><year>2016</year></pub-date><pub-date pub-type="ppub"><season>Jul-Aug</season><year>2016</year></pub-date><volume>30</volume><issue>4</issue><issue-id pub-id-type="doi">10.1111/jvim.2016.30.issue-4</issue-id><fpage>1031</fpage><lpage>1045</lpage><history><date date-type="received"><day>06</day><month>10</month><year>2015</year></date><date date-type="rev-recd"><day>26</day><month>4</month><year>2016</year></date><date date-type="accepted"><day>16</day><month>5</month><year>2016</year></date></history><permissions><pmc-comment> © 2016 American College of Veterinary Internal Medicine </pmc-comment>
<copyright-statement content-type="article-copyright">Copyright © 2016 The Authors. <italic>Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine</italic>.</copyright-statement><license license-type="creativeCommonsBy-nc"><license-p>This is an open access article under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution‐NonCommercial</ext-link> License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.</license-p></license></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="file:JVIM-30-1031.pdf"></self-uri><abstract id="jvim14356-abs-0001"><sec id="jvim14356-sec-0001"><title>Background</title><p>The term triaditis designates the concurrent presence of idiopathic inflammatory bowel disease (<styled-content style="fixed-case">IBD</styled-content>), cholangitis, and pancreatitis in cats.</p></sec><sec id="jvim14356-sec-0002"><title>Hypothesis/Objectives</title><p>The histopathology of concurrent, but often subclinical, inflammatory processes in the small intestine, liver, and pancreas of cats is poorly described. We aimed to investigate the frequency of enteritis, cholangitis, pancreatitis, or some combination of these in symptomatic and asymptomatic cats, compare clinicopathological features, and correlate histopathological with laboratory findings.</p></sec><sec id="jvim14356-sec-0003"><title>Animals</title><p>Domestic cats (27 symptomatic, 20 asymptomatic, and 8 normal).</p></sec><sec id="jvim14356-sec-0004"><title>Methods</title><p>Prospective study. Physical examination, laboratory variables (<styled-content style="fixed-case">CBC</styled-content>, serum biochemistry profile, serum thyroxine concentration, serum feline trypsin‐like immunoreactivity [<styled-content style="fixed-case">fTLI</styled-content>], feline lipase immunoreactivity [<styled-content style="fixed-case">fPLI</styled-content>, as measured by Spec <styled-content style="fixed-case">fPL</styled-content><sup>®</sup>], urinalysis, and fecal analysis), imaging, and histopathological examinations were conducted. Feline liver, pancreas, and small intestine were biopsied during laparotomy.</p></sec><sec id="jvim14356-sec-0005"><title>Results</title><p>Inflammatory lesions were detected in 47 cats (27 symptomatic, 20 asymptomatic). In total, 20 cats had histopathologic lesions of <styled-content style="fixed-case">IBD</styled-content> (13/47, 27.7%), cholangitis (6/47, 12.8%), or pancreatitis (1/47, 2.1%) alone, or inflammation involving >1 organ (27/47, 57.4%). More specifically, 16/47 cats (34.0%) had concurrent lesions of <styled-content style="fixed-case">IBD</styled-content> and cholangitis, 3/47 (6.4%) of <styled-content style="fixed-case">IBD</styled-content> and pancreatitis, and 8/47 cats (17%) of triaditis. Triaditis was identified only in symptomatic cats (8/27, 29.6%). A mild, positive correlation was detected between the severity (score) of <styled-content style="fixed-case">IBD</styled-content> lesions and the number of comorbidities (rho = +0.367, <italic>P</italic> = .022).</p></sec><sec id="jvim14356-sec-0006"><title>Conclusions and Clinical Importance</title><p>Histopathological evidence of <styled-content style="fixed-case">IBD</styled-content> or <styled-content style="fixed-case">IBD</styled-content> with comorbidities was detected in both symptomatic and asymptomatic cats. The possibility of triaditis should be considered in symptomatic cats with severe <styled-content style="fixed-case">IBD</styled-content>.</p></sec></abstract><kwd-group kwd-group-type="author-generated"><kwd id="jvim14356-kwd-0001">Cat</kwd><kwd id="jvim14356-kwd-0002">Cholangitis</kwd><kwd id="jvim14356-kwd-0003">Inflammatory Bowel Disease</kwd><kwd id="jvim14356-kwd-0004">Pancreatitis</kwd></kwd-group><funding-group><award-group><funding-source>NSF‐national scholarships foundation</funding-source><award-id>5321</award-id></award-group></funding-group><counts><page-count count="15"></page-count></counts><custom-meta-group><custom-meta><meta-name>source-schema-version-number</meta-name><meta-value>2.0</meta-value></custom-meta><custom-meta><meta-name>component-id</meta-name><meta-value>jvim14356</meta-value></custom-meta><custom-meta><meta-name>cover-date</meta-name><meta-value>July/August 2016</meta-value></custom-meta><custom-meta><meta-name>details-of-publishers-convertor</meta-name><meta-value>Converter:WILEY_ML3GV2_TO_NLMPMC version:4.9.2 mode:remove_FC converted:27.07.2016</meta-value></custom-meta></custom-meta-group></article-meta><notes><fn-group id="jvim14356-ntgp-0111"><fn id="jvim14356-note-0231"><p>The study was conducted at the Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.</p></fn><fn id="jvim14356-note-0251"><p>The data were presented in part at the 22nd Annual Congress of the European College of Veterinary Internal Medicine‐Companion Animals, 6–8 September 2012, Maastricht, The Netherlands</p></fn></fn-group></notes></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Adamama Oraitou, K K" sort="Adamama Oraitou, K K" uniqKey="Adamama Oraitou K" first="K. K." last="Adamama-Moraitou">K. K. Adamama-Moraitou</name><name sortKey="Fragkou, F C" sort="Fragkou, F C" uniqKey="Fragkou F" first="F. C." last="Fragkou">F. C. Fragkou</name><name sortKey="Kritsepi Onstantinou, M" sort="Kritsepi Onstantinou, M" uniqKey="Kritsepi Onstantinou M" first="M." last="Kritsepi-Konstantinou">M. Kritsepi-Konstantinou</name><name sortKey="Lidbury, J A" sort="Lidbury, J A" uniqKey="Lidbury J" first="J. A." last="Lidbury">J. A. Lidbury</name><name sortKey="Poutahidis, T" sort="Poutahidis, T" uniqKey="Poutahidis T" first="T." last="Poutahidis">T. Poutahidis</name><name sortKey="Prassinos, N N" sort="Prassinos, N N" uniqKey="Prassinos N" first="N. N." last="Prassinos">N. N. Prassinos</name><name sortKey="Rallis, T S" sort="Rallis, T S" uniqKey="Rallis T" first="T. S." last="Rallis">T. S. Rallis</name><name sortKey="Steiner, J M" sort="Steiner, J M" uniqKey="Steiner J" first="J. M." last="Steiner">J. M. Steiner</name><name sortKey="Suchodolski, J S" sort="Suchodolski, J S" uniqKey="Suchodolski J" first="J. S." last="Suchodolski">J. S. Suchodolski</name><name sortKey="Xenoulis, P G" sort="Xenoulis, P G" uniqKey="Xenoulis P" first="P. G." last="Xenoulis">P. G. Xenoulis</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000244 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000244 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:5089651
|texte= Prevalence and Clinicopathological Features of Triaditis in a Prospective Case Series of Symptomatic and Asymptomatic Cats
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:27296565" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a CovidV1
| This area was generated with Dilib version V0.6.33. |  |