Case report: Detection of the Middle East respiratory syndrome corona virus (MERS-CoV) in nasal secretions of a dead human
Identifieur interne : 000225 ( Pmc/Checkpoint ); précédent : 000224; suivant : 000226Case report: Detection of the Middle East respiratory syndrome corona virus (MERS-CoV) in nasal secretions of a dead human
Auteurs : Waleed H. MahallawiSource :
- Journal of Taibah University Medical Sciences [ 1658-3612 ] ; 2017.
Abstract
The Middle East respiratory syndrome coronavirus (MERS-CoV) has been recognized as a highly pathogenic virus that infects the human respiratory tract and has high morbidity and mortality. The MERS-CoV is a huge burden on Saudi Arabian health-care facilities, causing approximately 40% mortality. The transmission mechanism of the virus is still not well understood. Therefore, the prevention of any route of transmission is the best measure to arrest the spread of this disease. Using the real time polymerase chain reaction (RT-PCR), MERS-CoV was detected in the nasal secretions of a human cadaver. Full precautions should be applied and carefully followed to prevent the transmission of the virus, especially among health care workers.
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DOI: 10.1016/j.jtumed.2017.07.004
PubMed: 31435338
PubMed Central: 6695009
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Mahallawi</name></author></analytic><series><title level="j">Journal of Taibah University Medical Sciences</title><idno type="eISSN">1658-3612</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The Middle East respiratory syndrome coronavirus (MERS-CoV) has been recognized as a highly pathogenic virus that infects the human respiratory tract and has high morbidity and mortality. The MERS-CoV is a huge burden on Saudi Arabian health-care facilities, causing approximately 40% mortality. The transmission mechanism of the virus is still not well understood. Therefore, the prevention of any route of transmission is the best measure to arrest the spread of this disease. Using the real time polymerase chain reaction (RT-PCR), MERS-CoV was detected in the nasal secretions of a human cadaver. Full precautions should be applied and carefully followed to prevent the transmission of the virus, especially among health care workers.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Thomas, C" uniqKey="Thomas C">C. Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almaghrabi, R S" uniqKey="Almaghrabi R">R.S. Almaghrabi</name></author><author><name sortKey="Omrani, A S" uniqKey="Omrani A">A.S. Omrani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, W J" uniqKey="Liu W">W.J. Liu</name></author><author><name sortKey="Zhao, M" uniqKey="Zhao M">M. Zhao</name></author><author><name sortKey="Liu, K" uniqKey="Liu K">K. Liu</name></author><author><name sortKey="Xu, K" uniqKey="Xu K">K. Xu</name></author><author><name sortKey="Wong, G" uniqKey="Wong G">G. Wong</name></author><author><name sortKey="Tan, W" uniqKey="Tan W">W. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Taibah Univ Med Sci</journal-id><journal-id journal-id-type="iso-abbrev">J Taibah Univ Med Sci</journal-id><journal-title-group><journal-title>Journal of Taibah University Medical Sciences</journal-title></journal-title-group><issn pub-type="epub">1658-3612</issn><publisher><publisher-name>Taibah University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31435338</article-id><article-id pub-id-type="pmc">6695009</article-id><article-id pub-id-type="publisher-id">S1658-3612(17)30121-X</article-id><article-id pub-id-type="doi">10.1016/j.jtumed.2017.07.004</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Case report: Detection of the Middle East respiratory syndrome corona virus (MERS-CoV) in nasal secretions of a dead human</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Mahallawi</surname><given-names>Waleed H.</given-names></name><degrees>PhD</degrees><email>wmahallawi@taibahu.edu.sa</email><xref rid="cor1" ref-type="corresp">∗</xref></contrib></contrib-group><aff id="aff1">Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Almadinah Almunawwarah, KSA</aff><author-notes><corresp id="cor1"><label>∗</label>Corresponding address: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Almadinah Almunawwarah, Prince Naif bin Abdulaziz Rd, 300, KSA. <email>wmahallawi@taibahu.edu.sa</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>16</day><month>8</month><year>2017</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="collection"><month>6</month><year>2018</year></pub-date><pub-date pub-type="epub"><day>16</day><month>8</month><year>2017</year></pub-date><volume>13</volume><issue>3</issue><fpage>302</fpage><lpage>304</lpage><history><date date-type="received"><day>23</day><month>5</month><year>2017</year></date><date date-type="rev-recd"><day>17</day><month>7</month><year>2017</year></date><date date-type="accepted"><day>23</day><month>7</month><year>2017</year></date></history><permissions><copyright-statement>© 2017 The Author</copyright-statement><copyright-year>2017</copyright-year><license license-type="CC BY-NC-ND" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/"><license-p>This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).</license-p></license></permissions><abstract id="abs0015"><p>The Middle East respiratory syndrome coronavirus (MERS-CoV) has been recognized as a highly pathogenic virus that infects the human respiratory tract and has high morbidity and mortality. The MERS-CoV is a huge burden on Saudi Arabian health-care facilities, causing approximately 40% mortality. The transmission mechanism of the virus is still not well understood. Therefore, the prevention of any route of transmission is the best measure to arrest the spread of this disease. Using the real time polymerase chain reaction (RT-PCR), MERS-CoV was detected in the nasal secretions of a human cadaver. Full precautions should be applied and carefully followed to prevent the transmission of the virus, especially among health care workers.</p></abstract><trans-abstract xml:lang="ar"><title>الملخص</title><p>يُعرف فيروس ”كورونا“ المسبب لمتلازمة الشرق الأوسط التنفسية على أنه فيروس شديد العدوى يصيب الجهاز التنفسي مع معدلات مرتفعة في المضاعفات والوفيات. يُحمِّل فيروس كورونا المسبب لمتلازمة الشرق الأوسط التنفسية عبئا كبيرا على مرافق الرعاية الصحية في المملكة العربية السعودية بنسبة وفيات تقارب الـ ٤٠٪. ولا يزال انتقال الفيروس غير مفهوم بشكل جيد. ولذلك، فإن منع أي طريق للانتقال هو أفضل وسيلة لمنع انتشار هذا المرض. تم باستخدام تفاعل البوليميرايز المتسلسل الآني، الكشف عن فيروس كورونا المسبب لمتلازمة الشرق الأوسط التنفسية في الافرازات الأنفية لجثة. لذا ينبغي تطبيق الاحتياطات الكاملة ومتابعتها لمنع انتقال الفيروس، خاصة بين العاملين في مجال الرعاية الصحية.</p></trans-abstract><kwd-group xml:lang="ar" id="kwrds0010"><title>الكلمات المفتاحية</title><kwd>العاملين في مجال الرعاية الصحية</kwd><kwd>فيروس كورونا المسبب لمتلازمة الشرق الأوسط التنفسية</kwd><kwd>الوقاية</kwd><kwd>انتقال المرض</kwd></kwd-group><kwd-group id="kwrds0015"><title>Keywords</title><kwd>Health care workers</kwd><kwd>Infection control</kwd><kwd>MERS-CoV</kwd><kwd>Postmortem</kwd><kwd>Prevention</kwd><kwd>Transmission</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Mahallawi, Waleed H" sort="Mahallawi, Waleed H" uniqKey="Mahallawi W" first="Waleed H." last="Mahallawi">Waleed H. Mahallawi</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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