Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature
Identifieur interne : 000068 ( Pmc/Checkpoint ); précédent : 000067; suivant : 000069Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature
Auteurs : Keisuke Matsuo [Japon] ; Takashi Ishiguro [Japon] ; Takatomo Najama [Japon] ; Yoshihiko Shimizu [Japon] ; Yasuhito Kobayashi [Japon] ; Makoto Mutou [Japon]Source :
- Internal Medicine [ 0918-2918 ] ; 2019.
Abstract
A 62-year-old man presented to our hospital for the further evaluation and treatment of his back pain, general fatigue, and dyspnea, which had developed 4 days after the 29th administration of nivolumab to treat his lung cancer. Based on his clinical history, elevated serum cardiac enzyme values, and cardiac magnetic resonance (CMR) imaging and myocardial biopsy findings, he was diagnosed with myocarditis induced by nivolumab. Corticosteroid therapy improved his condition, and CMR performed on hospital day 11 also showed remarkable improvement. Although nivolumab-induced myocarditis is rare, cardiologists should consider it when encountering patients treated with such a drug for malignant disease.
Url:
DOI: 10.2169/internalmedicine.2596-18
PubMed: 31118387
PubMed Central: 6746646
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:6746646Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature</title>
<author><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Department of Cardiology, Saitama Medical University International Medical Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Medical University International Medical Center</wicri:regionArea>
<wicri:noRegion>Saitama Medical University International Medical Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ishiguro, Takashi" sort="Ishiguro, Takashi" uniqKey="Ishiguro T" first="Takashi" last="Ishiguro">Takashi Ishiguro</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Najama, Takatomo" sort="Najama, Takatomo" uniqKey="Najama T" first="Takatomo" last="Najama">Takatomo Najama</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shimizu, Yoshihiko" sort="Shimizu, Yoshihiko" uniqKey="Shimizu Y" first="Yoshihiko" last="Shimizu">Yoshihiko Shimizu</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Department of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pathology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kobayashi, Yasuhito" sort="Kobayashi, Yasuhito" uniqKey="Kobayashi Y" first="Yasuhito" last="Kobayashi">Yasuhito Kobayashi</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Department of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pathology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mutou, Makoto" sort="Mutou, Makoto" uniqKey="Mutou M" first="Makoto" last="Mutou">Makoto Mutou</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">31118387</idno>
<idno type="pmc">6746646</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746646</idno>
<idno type="RBID">PMC:6746646</idno>
<idno type="doi">10.2169/internalmedicine.2596-18</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">000313</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000313</idno>
<idno type="wicri:Area/Pmc/Curation">000313</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000313</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000068</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000068</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature</title>
<author><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Department of Cardiology, Saitama Medical University International Medical Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Medical University International Medical Center</wicri:regionArea>
<wicri:noRegion>Saitama Medical University International Medical Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ishiguro, Takashi" sort="Ishiguro, Takashi" uniqKey="Ishiguro T" first="Takashi" last="Ishiguro">Takashi Ishiguro</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Najama, Takatomo" sort="Najama, Takatomo" uniqKey="Najama T" first="Takatomo" last="Najama">Takatomo Najama</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shimizu, Yoshihiko" sort="Shimizu, Yoshihiko" uniqKey="Shimizu Y" first="Yoshihiko" last="Shimizu">Yoshihiko Shimizu</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Department of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pathology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kobayashi, Yasuhito" sort="Kobayashi, Yasuhito" uniqKey="Kobayashi Y" first="Yasuhito" last="Kobayashi">Yasuhito Kobayashi</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Department of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pathology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mutou, Makoto" sort="Mutou, Makoto" uniqKey="Mutou M" first="Makoto" last="Mutou">Makoto Mutou</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea>
<wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Internal Medicine</title>
<idno type="ISSN">0918-2918</idno>
<idno type="eISSN">1349-7235</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>A 62-year-old man presented to our hospital for the further evaluation and treatment of his back pain, general fatigue, and dyspnea, which had developed 4 days after the 29th administration of nivolumab to treat his lung cancer. Based on his clinical history, elevated serum cardiac enzyme values, and cardiac magnetic resonance (CMR) imaging and myocardial biopsy findings, he was diagnosed with myocarditis induced by nivolumab. Corticosteroid therapy improved his condition, and CMR performed on hospital day 11 also showed remarkable improvement. Although nivolumab-induced myocarditis is rare, cardiologists should consider it when encountering patients treated with such a drug for malignant disease. </p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Semper, H" uniqKey="Semper H">H Semper</name>
</author>
<author><name sortKey="Muehlberg, F" uniqKey="Muehlberg F">F Muehlberg</name>
</author>
<author><name sortKey="Schulz Menger, J" uniqKey="Schulz Menger J">J Schulz-Menger</name>
</author>
<author><name sortKey="Allewelt, M" uniqKey="Allewelt M">M Allewelt</name>
</author>
<author><name sortKey="Grohe, C" uniqKey="Grohe C">C Grohe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tay, Ry" uniqKey="Tay R">RY Tay</name>
</author>
<author><name sortKey="Blackley, E" uniqKey="Blackley E">E Blackley</name>
</author>
<author><name sortKey="Mclean, C" uniqKey="Mclean C">C McLean</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gibson, R" uniqKey="Gibson R">R Gibson</name>
</author>
<author><name sortKey="Delaune, J" uniqKey="Delaune J">J Delaune</name>
</author>
<author><name sortKey="Szady, A" uniqKey="Szady A">A Szady</name>
</author>
<author><name sortKey="Markham, M" uniqKey="Markham M">M Markham</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tadokoro, T" uniqKey="Tadokoro T">T Tadokoro</name>
</author>
<author><name sortKey="Keshino, E" uniqKey="Keshino E">E Keshino</name>
</author>
<author><name sortKey="Makiyama, A" uniqKey="Makiyama A">A Makiyama</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tajmir Riahi, A" uniqKey="Tajmir Riahi A">A Tajmir-Riahi</name>
</author>
<author><name sortKey="Bergmann, T" uniqKey="Bergmann T">T Bergmann</name>
</author>
<author><name sortKey="Schmid, M" uniqKey="Schmid M">M Schmid</name>
</author>
<author><name sortKey="Agaimy, A" uniqKey="Agaimy A">A Agaimy</name>
</author>
<author><name sortKey="Schuler, G" uniqKey="Schuler G">G Schuler</name>
</author>
<author><name sortKey="Heinzerling, L" uniqKey="Heinzerling L">L Heinzerling</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Norwood, Tg" uniqKey="Norwood T">TG Norwood</name>
</author>
<author><name sortKey="Westbrook, Bc" uniqKey="Westbrook B">BC Westbrook</name>
</author>
<author><name sortKey="Johnson, Db" uniqKey="Johnson D">DB Johnson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tawbi, Ha" uniqKey="Tawbi H">HA Tawbi</name>
</author>
<author><name sortKey="Forsyth, Pa" uniqKey="Forsyth P">PA Forsyth</name>
</author>
<author><name sortKey="Algazi, A" uniqKey="Algazi A">A Algazi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Johnson, Db" uniqKey="Johnson D">DB Johnson</name>
</author>
<author><name sortKey="Balko, Jm" uniqKey="Balko J">JM Balko</name>
</author>
<author><name sortKey="Compton, Ml" uniqKey="Compton M">ML Compton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kimura, T" uniqKey="Kimura T">T Kimura</name>
</author>
<author><name sortKey="Fukushima, S" uniqKey="Fukushima S">S Fukushima</name>
</author>
<author><name sortKey="Miyashita, A" uniqKey="Miyashita A">A Miyashita</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Heinzerling, L" uniqKey="Heinzerling L">L Heinzerling</name>
</author>
<author><name sortKey="Ott, Pa" uniqKey="Ott P">PA Ott</name>
</author>
<author><name sortKey="Hodi, Fs" uniqKey="Hodi F">FS Hodi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Matson, Dr" uniqKey="Matson D">DR Matson</name>
</author>
<author><name sortKey="Accola, Ma" uniqKey="Accola M">MA Accola</name>
</author>
<author><name sortKey="Rehrauer, Wm" uniqKey="Rehrauer W">WM Rehrauer</name>
</author>
<author><name sortKey="Corliss, Rf" uniqKey="Corliss R">RF Corliss</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fukasawa, Y" uniqKey="Fukasawa Y">Y Fukasawa</name>
</author>
<author><name sortKey="Sasaki, K" uniqKey="Sasaki K">K Sasaki</name>
</author>
<author><name sortKey="Natsume, M" uniqKey="Natsume M">M Natsume</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Detterbeck, Fc" uniqKey="Detterbeck F">FC Detterbeck</name>
</author>
<author><name sortKey="Boffa, Dj" uniqKey="Boffa D">DJ Boffa</name>
</author>
<author><name sortKey="Kim, Aw" uniqKey="Kim A">AW Kim</name>
</author>
<author><name sortKey="Tanoue, Lt" uniqKey="Tanoue L">LT Tanoue</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wolchok, Jd" uniqKey="Wolchok J">JD Wolchok</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Varricchi, G" uniqKey="Varricchi G">G Varricchi</name>
</author>
<author><name sortKey="Galdiero, Mr" uniqKey="Galdiero M">MR Galdiero</name>
</author>
<author><name sortKey="Marone, G" uniqKey="Marone G">G Marone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mahrholdt, H" uniqKey="Mahrholdt H">H Mahrholdt</name>
</author>
<author><name sortKey="Goedecke, C" uniqKey="Goedecke C">C Goedecke</name>
</author>
<author><name sortKey="Wagner, A" uniqKey="Wagner A">A Wagner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brahmer, Jr" uniqKey="Brahmer J">JR Brahmer</name>
</author>
<author><name sortKey="Lacchetti, C" uniqKey="Lacchetti C">C Lacchetti</name>
</author>
<author><name sortKey="Schneider, Bj" uniqKey="Schneider B">BJ Schneider</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Intern Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Intern. Med</journal-id>
<journal-title-group><journal-title>Internal Medicine</journal-title>
</journal-title-group>
<issn pub-type="ppub">0918-2918</issn>
<issn pub-type="epub">1349-7235</issn>
<publisher><publisher-name>The Japanese Society of Internal Medicine</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">31118387</article-id>
<article-id pub-id-type="pmc">6746646</article-id>
<article-id pub-id-type="doi">10.2169/internalmedicine.2596-18</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Matsuo</surname>
<given-names>Keisuke</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ishiguro</surname>
<given-names>Takashi</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Najama</surname>
<given-names>Takatomo</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shimizu</surname>
<given-names>Yoshihiko</given-names>
</name>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kobayashi</surname>
<given-names>Yasuhito</given-names>
</name>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mutou</surname>
<given-names>Makoto</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<aff id="aff1"><label>1</label>
Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</aff>
<aff id="aff2"><label>2</label>
Department of Cardiology, Saitama Medical University International Medical Center, Japan</aff>
<aff id="aff3"><label>3</label>
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan</aff>
<aff id="aff4"><label>4</label>
Department of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</aff>
</contrib-group>
<author-notes><fn><p>Correspondence to Dr. Keisuke Matsuo, <email>keisuke07171315@gmail.com</email>
</p>
</fn>
</author-notes>
<pub-date pub-type="epub"><day>22</day>
<month>5</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="ppub"><day>15</day>
<month>8</month>
<year>2019</year>
</pub-date>
<volume>58</volume>
<issue>16</issue>
<fpage>2367</fpage>
<lpage>2372</lpage>
<history><date date-type="received"><day>28</day>
<month>12</month>
<year>2018</year>
</date>
<date date-type="accepted"><day>14</day>
<month>2</month>
<year>2019</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2019 by The Japanese Society of Internal Medicine</copyright-statement>
<license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/"><license-p><pmc-comment>CREATIVE COMMONS</pmc-comment>
The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ext-link>
).</license-p>
</license>
</permissions>
<abstract><p>A 62-year-old man presented to our hospital for the further evaluation and treatment of his back pain, general fatigue, and dyspnea, which had developed 4 days after the 29th administration of nivolumab to treat his lung cancer. Based on his clinical history, elevated serum cardiac enzyme values, and cardiac magnetic resonance (CMR) imaging and myocardial biopsy findings, he was diagnosed with myocarditis induced by nivolumab. Corticosteroid therapy improved his condition, and CMR performed on hospital day 11 also showed remarkable improvement. Although nivolumab-induced myocarditis is rare, cardiologists should consider it when encountering patients treated with such a drug for malignant disease. </p>
</abstract>
<kwd-group kwd-group-type="author"><kwd>cardiac magnetic resonance imaging</kwd>
<kwd>corticosteroid</kwd>
<kwd>lung cancer</kwd>
<kwd>myocarditis</kwd>
<kwd>nivolumab</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><country name="Japon"><noRegion><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name>
</noRegion>
<name sortKey="Ishiguro, Takashi" sort="Ishiguro, Takashi" uniqKey="Ishiguro T" first="Takashi" last="Ishiguro">Takashi Ishiguro</name>
<name sortKey="Kobayashi, Yasuhito" sort="Kobayashi, Yasuhito" uniqKey="Kobayashi Y" first="Yasuhito" last="Kobayashi">Yasuhito Kobayashi</name>
<name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name>
<name sortKey="Mutou, Makoto" sort="Mutou, Makoto" uniqKey="Mutou M" first="Makoto" last="Mutou">Makoto Mutou</name>
<name sortKey="Najama, Takatomo" sort="Najama, Takatomo" uniqKey="Najama T" first="Takatomo" last="Najama">Takatomo Najama</name>
<name sortKey="Shimizu, Yoshihiko" sort="Shimizu, Yoshihiko" uniqKey="Shimizu Y" first="Yoshihiko" last="Shimizu">Yoshihiko Shimizu</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000068 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000068 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV1 |flux= Pmc |étape= Checkpoint |type= RBID |clé= PMC:6746646 |texte= Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:31118387" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a CovidV1
This area was generated with Dilib version V0.6.33. |