Three‐dimensional Sequential Study of the Intestinal Surface in Experimental Porcine CV 777 Coronavirus Enteritis
Identifieur interne : 001705 ( Main/Exploration ); précédent : 001704; suivant : 001706Three‐dimensional Sequential Study of the Intestinal Surface in Experimental Porcine CV 777 Coronavirus Enteritis
Auteurs : R. Ducatelle [Belgique] ; W. Coussement ; G. Charlier ; P. Debouck ; J. HoorensSource :
- Zentralblatt für Veterinärmedizin Reihe B [ 0931-2021 ] ; 1981-08.
Abstract
The intestinal surface of piglets, experimentally infected with the CV777 coronavirus, was studied at different time intervals using stereo‐microscopy, histology and scanning electron microscopy. Desquamation of epithelial cells was most severe on jejunal villi at the time of onset of clinical signs. It was also seen at 6h after the onset of clinical signs in the ileum. Duodenum and colon remained normal. From 24h after the first clinical signs onwards, villous fusion was seen. The alterations of the mucosal surface are compared to those seen in other enteropathogenic conditions of pigs.
Rasterelektronen‐ und stereomikroskopische Untersuchung der Darmoberfläche nach experimenteller Infektion mit dem porcinen Coronavirus CV777 Die Darmoberfläche von experimentell mit CV 777 infizierten Ferkeln wurde nach bestimmten Zeitintervallen mit Hilfe der Stereo‐ und einfachen Lichtmikroskopie sowie mit dem Raster‐Elektronenmikroskop untersucht. Bei Auftreten der ersten klinischen Symptome sowie sechs Stunden danach war die Desquamation der Epithelzellen des Jejunums am ausgeprägtesten. Ab 24 Stunden nach der Infektion wurde eine Verschmelzung der Zotten untereinander beobachtet. Die Veränderungen der Schleimhautoberfläche werden mit denen bei anderen enteropathogenen Prozessen verglichen.
Estudios con el microscopio electrónico de trazados y con el estereo de la superficie intestinal tras la infección experimental con el virus corona porcino CV 777 Se examinó la superficie intestinal de lechones infectados experimental‐mente con CV 777 tras ciertos intervalos de tiempo con ayuda de la estereo‐microscopía y del microscopio óptico simple, así como con el microscopio electrónico de trazados. Al aparecer los síntomas clínicos primeros y seis horas después era muy manifiesta la descamación de las células epiteliales en el yeyuno. A partir de las 24 horas tras la infección se observó una coalescencia de las vellosidades entre sí. Las modificaciones en la superficie mucosa se comparan con las de los otros procesos enteropatógenos.
Url:
DOI: 10.1111/j.1439-0450.1981.tb01765.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000417
- to stream Istex, to step Curation: 000397
- to stream Istex, to step Checkpoint: 000816
- to stream Main, to step Merge: 001734
- to stream Main, to step Curation: 001705
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Three‐dimensional Sequential Study of the Intestinal Surface in Experimental Porcine CV 777 Coronavirus Enteritis</title><author><name sortKey="Ducatelle, R" sort="Ducatelle, R" uniqKey="Ducatelle R" first="R." last="Ducatelle">R. Ducatelle</name></author><author><name sortKey="Coussement, W" sort="Coussement, W" uniqKey="Coussement W" first="W." last="Coussement">W. Coussement</name></author><author><name sortKey="Charlier, G" sort="Charlier, G" uniqKey="Charlier G" first="G." last="Charlier">G. Charlier</name></author><author><name sortKey="Debouck, P" sort="Debouck, P" uniqKey="Debouck P" first="P." last="Debouck">P. Debouck</name></author><author><name sortKey="Hoorens, J" sort="Hoorens, J" uniqKey="Hoorens J" first="J." last="Hoorens">J. Hoorens</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9CD1563BF8F099029A72390EF3F632FBEE6A3267</idno><date when="1981" year="1981">1981</date><idno type="doi">10.1111/j.1439-0450.1981.tb01765.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-WRWJ5HB1-9/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000417</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000417</idno><idno type="wicri:Area/Istex/Curation">000397</idno><idno type="wicri:Area/Istex/Checkpoint">000816</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000816</idno><idno type="wicri:doubleKey">0931-2021:1981:Ducatelle R:three:dimensional:sequential</idno><idno type="wicri:Area/Main/Merge">001734</idno><idno type="wicri:Area/Main/Curation">001705</idno><idno type="wicri:Area/Main/Exploration">001705</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Three‐dimensional Sequential Study of the Intestinal Surface in Experimental Porcine CV 777 Coronavirus Enteritis</title><author><name sortKey="Ducatelle, R" sort="Ducatelle, R" uniqKey="Ducatelle R" first="R." last="Ducatelle">R. Ducatelle</name><affiliation></affiliation><affiliation></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Correspondence address: Department of Veterinary Pathology, Faculty of Veterinary Medicine, State University of Gent, Casinoplein 24, B‐9000 Gent</wicri:regionArea><wicri:noRegion>B‐9000 Gent</wicri:noRegion></affiliation></author><author><name sortKey="Coussement, W" sort="Coussement, W" uniqKey="Coussement W" first="W." last="Coussement">W. Coussement</name><affiliation></affiliation><affiliation></affiliation><affiliation><wicri:noCountry code="subField">Pensaert</wicri:noCountry></affiliation></author><author><name sortKey="Charlier, G" sort="Charlier, G" uniqKey="Charlier G" first="G." last="Charlier">G. Charlier</name><affiliation></affiliation><affiliation></affiliation><affiliation><wicri:noCountry code="subField">Pensaert</wicri:noCountry></affiliation></author><author><name sortKey="Debouck, P" sort="Debouck, P" uniqKey="Debouck P" first="P." last="Debouck">P. Debouck</name><affiliation></affiliation><affiliation></affiliation><affiliation><wicri:noCountry code="subField">Pensaert</wicri:noCountry></affiliation></author><author><name sortKey="Hoorens, J" sort="Hoorens, J" uniqKey="Hoorens J" first="J." last="Hoorens">J. Hoorens</name><affiliation></affiliation><affiliation></affiliation><affiliation><wicri:noCountry code="subField">Pensaert</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Zentralblatt für Veterinärmedizin Reihe B</title><title level="j" type="alt">ZENTRALBLATT FUR VETERINARMEDIZIN REIHE B</title><idno type="ISSN">0931-2021</idno><idno type="eISSN">1439-0450</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="483">483</biblScope><biblScope unit="page" to="493">493</biblScope><biblScope unit="page-count">11</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1981-08">1981-08</date></imprint><idno type="ISSN">0931-2021</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0931-2021</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The intestinal surface of piglets, experimentally infected with the CV777 coronavirus, was studied at different time intervals using stereo‐microscopy, histology and scanning electron microscopy. Desquamation of epithelial cells was most severe on jejunal villi at the time of onset of clinical signs. It was also seen at 6h after the onset of clinical signs in the ileum. Duodenum and colon remained normal. From 24h after the first clinical signs onwards, villous fusion was seen. The alterations of the mucosal surface are compared to those seen in other enteropathogenic conditions of pigs.</div><div type="abstract" xml:lang="de">Rasterelektronen‐ und stereomikroskopische Untersuchung der Darmoberfläche nach experimenteller Infektion mit dem porcinen Coronavirus CV777 Die Darmoberfläche von experimentell mit CV 777 infizierten Ferkeln wurde nach bestimmten Zeitintervallen mit Hilfe der Stereo‐ und einfachen Lichtmikroskopie sowie mit dem Raster‐Elektronenmikroskop untersucht. Bei Auftreten der ersten klinischen Symptome sowie sechs Stunden danach war die Desquamation der Epithelzellen des Jejunums am ausgeprägtesten. Ab 24 Stunden nach der Infektion wurde eine Verschmelzung der Zotten untereinander beobachtet. Die Veränderungen der Schleimhautoberfläche werden mit denen bei anderen enteropathogenen Prozessen verglichen.</div><div type="abstract" xml:lang="es">Estudios con el microscopio electrónico de trazados y con el estereo de la superficie intestinal tras la infección experimental con el virus corona porcino CV 777 Se examinó la superficie intestinal de lechones infectados experimental‐mente con CV 777 tras ciertos intervalos de tiempo con ayuda de la estereo‐microscopía y del microscopio óptico simple, así como con el microscopio electrónico de trazados. Al aparecer los síntomas clínicos primeros y seis horas después era muy manifiesta la descamación de las células epiteliales en el yeyuno. A partir de las 24 horas tras la infección se observó una coalescencia de las vellosidades entre sí. Las modificaciones en la superficie mucosa se comparan con las de los otros procesos enteropatógenos.</div></front></TEI><affiliations><list><country><li>Belgique</li></country></list><tree><noCountry><name sortKey="Charlier, G" sort="Charlier, G" uniqKey="Charlier G" first="G." last="Charlier">G. Charlier</name><name sortKey="Coussement, W" sort="Coussement, W" uniqKey="Coussement W" first="W." last="Coussement">W. Coussement</name><name sortKey="Debouck, P" sort="Debouck, P" uniqKey="Debouck P" first="P." last="Debouck">P. Debouck</name><name sortKey="Hoorens, J" sort="Hoorens, J" uniqKey="Hoorens J" first="J." last="Hoorens">J. Hoorens</name></noCountry><country name="Belgique"><noRegion><name sortKey="Ducatelle, R" sort="Ducatelle, R" uniqKey="Ducatelle R" first="R." last="Ducatelle">R. Ducatelle</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001705 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001705 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:9CD1563BF8F099029A72390EF3F632FBEE6A3267
|texte= Three‐dimensional Sequential Study of the Intestinal Surface in Experimental Porcine CV 777 Coronavirus Enteritis
}}
| This area was generated with Dilib version V0.6.33. |  |