Miniaturization for Point-of-Care Analysis: Platform Technology for Almost Every Biomedical Assay
Identifieur interne : 000B65 ( Main/Exploration ); précédent : 000B64; suivant : 000B66Miniaturization for Point-of-Care Analysis: Platform Technology for Almost Every Biomedical Assay
Auteurs : Soeren Schumacher ; Dorian Sartorius ; Eva Ehrentreich-Förster ; Frank F. BierSource :
- EJIFCC [ 1650-3414 ] ; 2012.
Abstract
Platform technologies for the changing need of diagnostics are one of the main challenges in medical device technology. From one point-of-view the demand for new and more versatile diagnostic is increasing due to a deeper knowledge of biomarkers and their combination with diseases. From another point-of-view a decentralization of diagnostics will occur since decisions can be made faster resulting in higher success of therapy. Hence, new types of technologies have to be established which enables a multiparameter analysis at the point-of-care. Within this review-like article a system called Fraunhofer ivD-platform is introduced. It consists of a credit-card sized cartridge with integrated reagents, sensors and pumps and a read-out/processing unit. Within the cartridge the assay runs fully automated within 15-20 minutes. Due to the open design of the platform different analyses such as antibody, serological or DNA-assays can be performed. Specific examples of these three different assay types are given to show the broad applicability of the system.
Url:
PubMed: 27683418
PubMed Central: 4975254
Affiliations:
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Bier</name><name sortKey="Ehrentreich Forster, Eva" sort="Ehrentreich Forster, Eva" uniqKey="Ehrentreich Forster E" first="Eva" last="Ehrentreich-Förster">Eva Ehrentreich-Förster</name><name sortKey="Sartorius, Dorian" sort="Sartorius, Dorian" uniqKey="Sartorius D" first="Dorian" last="Sartorius">Dorian Sartorius</name><name sortKey="Schumacher, Soeren" sort="Schumacher, Soeren" uniqKey="Schumacher S" first="Soeren" last="Schumacher">Soeren Schumacher</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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