The genetic code as expressed through relationships between mRNA structure and protein function
Identifieur interne : 000A77 ( Main/Exploration ); précédent : 000A76; suivant : 000A78The genetic code as expressed through relationships between mRNA structure and protein function
Auteurs : David M. Mauger ; Nathan A. Siegfried ; Kevin M. WeeksSource :
- FEBS letters [ 0014-5793 ] ; 2013.
Abstract
Structured RNA elements within messenger RNA often direct or modulate the cellular production of active proteins. As reviewed here, RNA structures have been discovered that govern nearly every step in protein production: mRNA production and stability; translation initiation, elongation, and termination; protein folding; and cellular localization. Regulatory RNA elements are common within RNAs from every domain of life. This growing body of RNA-mediated mechanisms continues to reveal new ways in which mRNA
Url:
DOI: 10.1016/j.febslet.2013.03.002
PubMed: 23499436
PubMed Central: 4269304
Affiliations:
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