Antibacterial activity and mechanism of action of Monarda punctata essential oil and its main components against common bacterial pathogens in respiratory tract
Identifieur interne : 000A48 ( Main/Exploration ); précédent : 000A47; suivant : 000A49Antibacterial activity and mechanism of action of Monarda punctata essential oil and its main components against common bacterial pathogens in respiratory tract
Auteurs : Hong Li ; Tian Yang ; Fei-Yan Li ; Yan Yao ; Zhong-Min SunSource :
- International Journal of Clinical and Experimental Pathology [ 1936-2625 ] ; 2014.
Abstract
The aim of the current research work was to study the chemical composition of the essential oil of
Url:
PubMed: 25550774
PubMed Central: 4270556
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000436
- to stream Pmc, to step Curation: 000436
- to stream Pmc, to step Checkpoint: 000426
- to stream Ncbi, to step Merge: 000429
- to stream Ncbi, to step Curation: 000429
- to stream Ncbi, to step Checkpoint: 000429
- to stream Main, to step Merge: 000A50
- to stream Main, to step Curation: 000A48
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antibacterial activity and mechanism of action of <italic>Monarda punctata</italic> essential oil and its main components against common bacterial pathogens in respiratory tract</title><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name></author><author><name sortKey="Yang, Tian" sort="Yang, Tian" uniqKey="Yang T" first="Tian" last="Yang">Tian Yang</name></author><author><name sortKey="Li, Fei Yan" sort="Li, Fei Yan" uniqKey="Li F" first="Fei-Yan" last="Li">Fei-Yan Li</name></author><author><name sortKey="Yao, Yan" sort="Yao, Yan" uniqKey="Yao Y" first="Yan" last="Yao">Yan Yao</name></author><author><name sortKey="Sun, Zhong Min" sort="Sun, Zhong Min" uniqKey="Sun Z" first="Zhong-Min" last="Sun">Zhong-Min Sun</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25550774</idno><idno type="pmc">4270556</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270556</idno><idno type="RBID">PMC:4270556</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000436</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000436</idno><idno type="wicri:Area/Pmc/Curation">000436</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000436</idno><idno type="wicri:Area/Pmc/Checkpoint">000426</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000426</idno><idno type="wicri:Area/Ncbi/Merge">000429</idno><idno type="wicri:Area/Ncbi/Curation">000429</idno><idno type="wicri:Area/Ncbi/Checkpoint">000429</idno><idno type="wicri:Area/Main/Merge">000A50</idno><idno type="wicri:Area/Main/Curation">000A48</idno><idno type="wicri:Area/Main/Exploration">000A48</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antibacterial activity and mechanism of action of <italic>Monarda punctata</italic> essential oil and its main components against common bacterial pathogens in respiratory tract</title><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name></author><author><name sortKey="Yang, Tian" sort="Yang, Tian" uniqKey="Yang T" first="Tian" last="Yang">Tian Yang</name></author><author><name sortKey="Li, Fei Yan" sort="Li, Fei Yan" uniqKey="Li F" first="Fei-Yan" last="Li">Fei-Yan Li</name></author><author><name sortKey="Yao, Yan" sort="Yao, Yan" uniqKey="Yao Y" first="Yan" last="Yao">Yan Yao</name></author><author><name sortKey="Sun, Zhong Min" sort="Sun, Zhong Min" uniqKey="Sun Z" first="Zhong-Min" last="Sun">Zhong-Min Sun</name></author></analytic><series><title level="j">International Journal of Clinical and Experimental Pathology</title><idno type="eISSN">1936-2625</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The aim of the current research work was to study the chemical composition of the essential oil of <italic>Monarda punctata</italic> along with evaluating the essential oil and its major components for their antibacterial effects against some frequently encountered respiratory infection causing pathogens. Gas chromatographic mass spectrometric analysis revealed the presence of 13 chemical constituents with thymol (75.2%), p-cymene (6.7%), limonene (5.4), and carvacrol (3.5%) as the major constituents. The oil composition was dominated by the oxygenated monoterpenes. Antibacterial activity of the essential oil and its major constituents (thymol, p-cymene, limonene) was evaluated against <italic>Streptococcus pyogenes, methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pneumoniae, Haemophilus influenzae and Escherichia coli</italic>. The study revealed that the essential oil and its constituents exhibited a broad spectrum and variable degree of antibacterial activity against different strains. Among the tested strains, <italic>Streptococcus pyogenes</italic>, <italic>Escherichia coli</italic> and <italic>Streptococcus pneumoniae</italic> were the most susceptible bacterial strain showing lowest MIC and MBC values. <italic>Methicillin-resistant Staphylococcus aureus</italic> was the most resistant bacterial strain to the essential oil treatment showing relatively higher MIC and MBC values. Scanning electron microscopy revealed that the essential oil induced potent and dose-dependent membrane damage in S. pyogenes and MRSA bacterial strains. The reactive oxygen species generated by the <italic>Monarda punctata</italic> essential oil were identified using 2’, 7’-dichlorofluorescein diacetate (DCFDA).This study indicated that the <italic>Monarda punctata</italic> essential oil to a great extent and thymol to a lower extent triggered a substantial increase in the ROS levels in <italic>S. pyogenes</italic> bacterial cultures which ultimately cause membrane damage as revealed by SEM results.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Li, Fei Yan" sort="Li, Fei Yan" uniqKey="Li F" first="Fei-Yan" last="Li">Fei-Yan Li</name><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name><name sortKey="Sun, Zhong Min" sort="Sun, Zhong Min" uniqKey="Sun Z" first="Zhong-Min" last="Sun">Zhong-Min Sun</name><name sortKey="Yang, Tian" sort="Yang, Tian" uniqKey="Yang T" first="Tian" last="Yang">Tian Yang</name><name sortKey="Yao, Yan" sort="Yao, Yan" uniqKey="Yao Y" first="Yan" last="Yao">Yan Yao</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A48 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A48 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4270556
|texte= Antibacterial activity and mechanism of action of Monarda punctata essential oil and its main components against common bacterial pathogens in respiratory tract
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25550774" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV1
| This area was generated with Dilib version V0.6.33. |  |