Essential oil of Artemisia vestita exhibits potent in vitro and in vivo antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement
Identifieur interne : 000959 ( Main/Exploration ); précédent : 000958; suivant : 000960Essential oil of Artemisia vestita exhibits potent in vitro and in vivo antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement
Auteurs : Chang Yang [République populaire de Chine] ; Dong-Hui Hu [République populaire de Chine] ; Yan Feng [République populaire de Chine]Source :
- Molecular Medicine Reports [ 1791-2997 ] ; 2015.
Abstract
The aim of the present study was to investigate the chemical composition of the essential oil of
Url:
DOI: 10.3892/mmr.2015.4210
PubMed: 26259564
PubMed Central: 4581751
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000025
- to stream Pmc, to step Curation: 000025
- to stream Pmc, to step Checkpoint: 000351
- to stream Ncbi, to step Merge: 000483
- to stream Ncbi, to step Curation: 000483
- to stream Ncbi, to step Checkpoint: 000483
- to stream Main, to step Merge: 000961
- to stream Main, to step Curation: 000959
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Essential oil of <italic>Artemisia vestita</italic> exhibits potent <italic>in vitro</italic> and <italic>in vivo</italic> antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement</title><author><name sortKey="Yang, Chang" sort="Yang, Chang" uniqKey="Yang C" first="Chang" last="Yang">Chang Yang</name><affiliation wicri:level="1"><nlm:aff id="af1-mmr-12-04-5762">Department of Respiratory Medicine, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Medicine, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author><author><name sortKey="Hu, Dong Hui" sort="Hu, Dong Hui" uniqKey="Hu D" first="Dong-Hui" last="Hu">Dong-Hui Hu</name><affiliation wicri:level="1"><nlm:aff id="af2-mmr-12-04-5762">Department of Liver Disease, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Liver Disease, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yan" sort="Feng, Yan" uniqKey="Feng Y" first="Yan" last="Feng">Yan Feng</name><affiliation wicri:level="1"><nlm:aff id="af3-mmr-12-04-5762">Department of Pathology, The First Hospital of Wuhan, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Pathology, The First Hospital of Wuhan, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26259564</idno><idno type="pmc">4581751</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581751</idno><idno type="RBID">PMC:4581751</idno><idno type="doi">10.3892/mmr.2015.4210</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000025</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000025</idno><idno type="wicri:Area/Pmc/Curation">000025</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000025</idno><idno type="wicri:Area/Pmc/Checkpoint">000351</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000351</idno><idno type="wicri:Area/Ncbi/Merge">000483</idno><idno type="wicri:Area/Ncbi/Curation">000483</idno><idno type="wicri:Area/Ncbi/Checkpoint">000483</idno><idno type="wicri:doubleKey">1791-2997:2015:Yang C:essential:oil:of</idno><idno type="wicri:Area/Main/Merge">000961</idno><idno type="wicri:Area/Main/Curation">000959</idno><idno type="wicri:Area/Main/Exploration">000959</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Essential oil of <italic>Artemisia vestita</italic> exhibits potent <italic>in vitro</italic> and <italic>in vivo</italic> antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement</title><author><name sortKey="Yang, Chang" sort="Yang, Chang" uniqKey="Yang C" first="Chang" last="Yang">Chang Yang</name><affiliation wicri:level="1"><nlm:aff id="af1-mmr-12-04-5762">Department of Respiratory Medicine, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Medicine, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author><author><name sortKey="Hu, Dong Hui" sort="Hu, Dong Hui" uniqKey="Hu D" first="Dong-Hui" last="Hu">Dong-Hui Hu</name><affiliation wicri:level="1"><nlm:aff id="af2-mmr-12-04-5762">Department of Liver Disease, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Liver Disease, Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yan" sort="Feng, Yan" uniqKey="Feng Y" first="Yan" last="Feng">Yan Feng</name><affiliation wicri:level="1"><nlm:aff id="af3-mmr-12-04-5762">Department of Pathology, The First Hospital of Wuhan, Wuhan, Hubei 430033, P.R. China</nlm:aff><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Pathology, The First Hospital of Wuhan, Wuhan, Hubei 430033</wicri:regionArea><wicri:noRegion>Hubei 430033</wicri:noRegion></affiliation></author></analytic><series><title level="j">Molecular Medicine Reports</title><idno type="ISSN">1791-2997</idno><idno type="eISSN">1791-3004</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The aim of the present study was to investigate the chemical composition of the essential oil of <italic>Artemisia vestita</italic> and to determine the antibacterial activity of the essential oil and its two major components, grandisol and 1,8-cineole, against certain respiratory infection-causing bacterial strains, <italic>in vitro</italic> and <italic>in vivo</italic>. The chemical composition of the essential oil was analyzed using gas chromatography-mass spectrometry. A micro-well dilution method was used to determine the minimum inhibition concentration (MIC) values of the essential oil and its major constituents. A model of <italic>Streptococcus pyogenes</italic> infection in mice was used to determine its <italic>in vivo</italic> activities. Lung and blood samples were obtained to assess bacterial cell counts. Toxicity evaluation of the essential oil and its components was completed by performing biochemical analysis of the serum, particularly monitoring aspartate transaminase, alanine transaminase, urea and creatinine. The essential oil exhibited potent antibacterial activity, whereas the two major constituents were less potent. The essential oil exhibited MIC values between 20 and 80 <italic>μ</italic>g/ml, while the values of the two constituents were between 130 and 200 <italic>μ</italic>g/ml. Scanning electron microscopy results demonstrated that the essential oil inhibited biofilm formation and altered its architecture. Survival curves indicated that the essential oil led to a reduction in the viability of different bacteria. The essential oil also induced significant leakage of potassium ions from <italic>S. pyogenes</italic>. The essential oil (100 <italic>μ</italic>g/mouse) and grandisol (135 <italic>μ</italic>g/mouse) significantly reduced the number of viable bacterial cells in the lungs (P<0.01). However, intake of 100 <italic>μ</italic>g/mouse of essential oil or grandisol 135 <italic>μ</italic>g/mouse once or twice each day for 9 days did not produce any toxic effects in the mice. In conclusion, the <italic>in vitro</italic> and <italic>in vivo</italic> results suggested that the essential oil of <italic>A. vestita</italic> and one of its major constituents, grandisol, can significantly inhibit the growth of different bacterial strains.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Eccles, Mp" uniqKey="Eccles M">MP Eccles</name></author><author><name sortKey="Grimshaw, Jm" uniqKey="Grimshaw J">JM Grimshaw</name></author><author><name sortKey="Johnston, M" uniqKey="Johnston M">M Johnston</name></author><author><name sortKey="Steen, N" uniqKey="Steen N">N Steen</name></author><author><name sortKey="Pitts, Nb" uniqKey="Pitts N">NB Pitts</name></author><author><name sortKey="Thomas, R" uniqKey="Thomas R">R Thomas</name></author><author><name sortKey="Glidewell, E" uniqKey="Glidewell E">E Glidewell</name></author><author><name sortKey="Maclennan, G" uniqKey="Maclennan G">G Maclennan</name></author><author><name sortKey="Bonetti, D" uniqKey="Bonetti D">D Bonetti</name></author><author><name sortKey="Walker, A" uniqKey="Walker A">A Walker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="M Kel, Mj" uniqKey="M Kel M">MJ Mäkelä</name></author><author><name sortKey="Puhakka, T" uniqKey="Puhakka T">T Puhakka</name></author><author><name sortKey="Ruuskanen, O" uniqKey="Ruuskanen O">O Ruuskanen</name></author><author><name sortKey="Leinonen, M" uniqKey="Leinonen M">M Leinonen</name></author><author><name sortKey="Saikku, P" uniqKey="Saikku P">P Saikku</name></author><author><name sortKey="Kimpim Ki, M" uniqKey="Kimpim Ki M">M Kimpimäki</name></author><author><name sortKey="Blomqvist, S" uniqKey="Blomqvist S">S Blomqvist</name></author><author><name sortKey="Hyypi, T" uniqKey="Hyypi T">T Hyypiä</name></author><author><name sortKey="Arstila, P" uniqKey="Arstila P">P Arstila</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Yang, T" uniqKey="Yang T">T Yang</name></author><author><name sortKey="Li, Fy" uniqKey="Li F">FY Li</name></author><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y Yao</name></author><author><name sortKey="Sun, Zm" uniqKey="Sun Z">ZM Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albert, Rh" uniqKey="Albert R">RH Albert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cohen, J" uniqKey="Cohen J">J Cohen</name></author><author><name sortKey="Powderly, W" uniqKey="Powderly W">W Powderly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cunningham, Mw" uniqKey="Cunningham M">MW Cunningham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aziz, Rk" uniqKey="Aziz R">RK Aziz</name></author><author><name sortKey="Kansal, R" uniqKey="Kansal R">R Kansal</name></author><author><name sortKey="Aronow, Bj" uniqKey="Aronow B">BJ Aronow</name></author><author><name sortKey="Taylor, Wl" uniqKey="Taylor W">WL Taylor</name></author><author><name sortKey="Rowe, Sl" uniqKey="Rowe S">SL Rowe</name></author><author><name sortKey="Kubal, M" uniqKey="Kubal M">M Kubal</name></author><author><name sortKey="Chhatwal, Gs" uniqKey="Chhatwal G">GS Chhatwal</name></author><author><name sortKey="Walker, Mj" uniqKey="Walker M">MJ Walker</name></author><author><name sortKey="Kotb, M" uniqKey="Kotb M">M Kotb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, Lg" uniqKey="Wilson L">LG Wilson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Carapetis, Jr" uniqKey="Carapetis J">JR Carapetis</name></author><author><name sortKey="Steer, Ac" uniqKey="Steer A">AC Steer</name></author><author><name sortKey="Mulholland, Ek" uniqKey="Mulholland E">EK Mulholland</name></author><author><name sortKey="Weber, M" uniqKey="Weber M">M Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang" uniqKey="Yang">Yang</name></author><author><name sortKey="Hu, Dh" uniqKey="Hu D">DH Hu</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y Feng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davies, J" uniqKey="Davies J">J Davies</name></author><author><name sortKey="Davies, D" uniqKey="Davies D">D Davies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rather, Ma" uniqKey="Rather M">MA Rather</name></author><author><name sortKey="Dar, Ba" uniqKey="Dar B">BA Dar</name></author><author><name sortKey="Dar, My" uniqKey="Dar M">MY Dar</name></author><author><name sortKey="Wani, Ba" uniqKey="Wani B">BA Wani</name></author><author><name sortKey="Shah, Wa" uniqKey="Shah W">WA Shah</name></author><author><name sortKey="Bhat, Ba" uniqKey="Bhat B">BA Bhat</name></author><author><name sortKey="Ganai, Ba" uniqKey="Ganai B">BA Ganai</name></author><author><name sortKey="Bhat, Ka" uniqKey="Bhat K">KA Bhat</name></author><author><name sortKey="Anand, R" uniqKey="Anand R">R Anand</name></author><author><name sortKey="Qurishi, Ma" uniqKey="Qurishi M">MA Qurishi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rashid, S" uniqKey="Rashid S">S Rashid</name></author><author><name sortKey="Rather, Ma" uniqKey="Rather M">MA Rather</name></author><author><name sortKey="Shah, Wa" uniqKey="Shah W">WA Shah</name></author><author><name sortKey="Bhat, Ba" uniqKey="Bhat B">BA Bhat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bakkali, F" uniqKey="Bakkali F">F Bakkali</name></author><author><name sortKey="Averbeck, S" uniqKey="Averbeck S">S Averbeck</name></author><author><name sortKey="Averbeck, D" uniqKey="Averbeck D">D Averbeck</name></author><author><name sortKey="Idaomar, M" uniqKey="Idaomar M">M Idaomar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edris, Ae" uniqKey="Edris A">AE Edris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rantzsch, U" uniqKey="Rantzsch U">U Rantzsch</name></author><author><name sortKey="Vacca, G" uniqKey="Vacca G">G Vacca</name></author><author><name sortKey="Duck, R" uniqKey="Duck R">R Dück</name></author><author><name sortKey="Gillissen, A" uniqKey="Gillissen A">A Gillissen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Federspil, P" uniqKey="Federspil P">P Federspil</name></author><author><name sortKey="Wulkow, R" uniqKey="Wulkow R">R Wulkow</name></author><author><name sortKey="Zimmermann, T" uniqKey="Zimmermann T">T Zimmermann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schindl, R" uniqKey="Schindl R">R Schindl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boyd, Em" uniqKey="Boyd E">EM Boyd</name></author><author><name sortKey="Sheppard, P" uniqKey="Sheppard P">P Sheppard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burrow, A" uniqKey="Burrow A">A Burrow</name></author><author><name sortKey="Eccles, R" uniqKey="Eccles R">R Eccles</name></author><author><name sortKey="Jones, As" uniqKey="Jones A">AS Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shubina, Lp" uniqKey="Shubina L">LP Shubina</name></author><author><name sortKey="Siurin, Sa" uniqKey="Siurin S">SA Siurin</name></author><author><name sortKey="Savchenko, Vm" uniqKey="Savchenko V">VM Savchenko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frohlich, E" uniqKey="Frohlich E">E Fröhlich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yin, Y" uniqKey="Yin Y">Y Yin</name></author><author><name sortKey="Gong, Fy" uniqKey="Gong F">FY Gong</name></author><author><name sortKey="Wu, Xx" uniqKey="Wu X">XX Wu</name></author><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author><author><name sortKey="Li, Yh" uniqKey="Li Y">YH Li</name></author><author><name sortKey="Chen, T" uniqKey="Chen T">T Chen</name></author><author><name sortKey="Xu, Q" uniqKey="Xu Q">Q Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Rx" uniqKey="Tan R">RX Tan</name></author><author><name sortKey="Lu, H" uniqKey="Lu H">H Lu</name></author><author><name sortKey="Wolfender, Jl" uniqKey="Wolfender J">JL Wolfender</name></author><author><name sortKey="Yu, Tt" uniqKey="Yu T">TT Yu</name></author><author><name sortKey="Zheng, Wf" uniqKey="Zheng W">WF Zheng</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name></author><author><name sortKey="Gafner, S" uniqKey="Gafner S">S Gafner</name></author><author><name sortKey="Hostettmann, K" uniqKey="Hostettmann K">K Hostettmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chowdhury, Ar" uniqKey="Chowdhury A">AR Chowdhury</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Adams, Rp" uniqKey="Adams R">RP Adams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ashour, Ml" uniqKey="Ashour M">ML Ashour</name></author><author><name sortKey="El Readi, M" uniqKey="El Readi M">M El-Readi</name></author><author><name sortKey="Youns, M" uniqKey="Youns M">M Youns</name></author><author><name sortKey="Mulyaningsih, S" uniqKey="Mulyaningsih S">S Mulyaningsih</name></author><author><name sortKey="Sporer, F" uniqKey="Sporer F">F Sporer</name></author><author><name sortKey="Efferth, T" uniqKey="Efferth T">T Efferth</name></author><author><name sortKey="Wink, M" uniqKey="Wink M">M Wink</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cox, Sd" uniqKey="Cox S">SD Cox</name></author><author><name sortKey="Gustafson, Je" uniqKey="Gustafson J">JE Gustafson</name></author><author><name sortKey="Mann, Cm" uniqKey="Mann C">CM Mann</name></author><author><name sortKey="Markham, Jl" uniqKey="Markham J">JL Markham</name></author><author><name sortKey="Liew, Yc" uniqKey="Liew Y">YC Liew</name></author><author><name sortKey="Hartland, Rp" uniqKey="Hartland R">RP Hartland</name></author><author><name sortKey="Bell, Hc" uniqKey="Bell H">HC Bell</name></author><author><name sortKey="Warmington, Jr" uniqKey="Warmington J">JR Warmington</name></author><author><name sortKey="Wyllie, Sg" uniqKey="Wyllie S">SG Wyllie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Villena, J" uniqKey="Villena J">J Villena</name></author><author><name sortKey="Medina, M" uniqKey="Medina M">M Medina</name></author><author><name sortKey="Racedo, S" uniqKey="Racedo S">S Racedo</name></author><author><name sortKey="Alvarez, S" uniqKey="Alvarez S">S Alvarez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Racedo, S" uniqKey="Racedo S">S Racedo</name></author><author><name sortKey="Villena, J" uniqKey="Villena J">J Villena</name></author><author><name sortKey="Medina, M" uniqKey="Medina M">M Medina</name></author><author><name sortKey="Aguero, G" uniqKey="Aguero G">G Agüero</name></author><author><name sortKey="Rodriguez, V" uniqKey="Rodriguez V">V Rodríguez</name></author><author><name sortKey="Alvarez, S" uniqKey="Alvarez S">S Alvarez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lopes Lutz, D" uniqKey="Lopes Lutz D">D Lopes-Lutz</name></author><author><name sortKey="Alviano, Ds" uniqKey="Alviano D">DS Alviano</name></author><author><name sortKey="Alviano, Cs" uniqKey="Alviano C">CS Alviano</name></author><author><name sortKey="Kolodziejczyk, Pp" uniqKey="Kolodziejczyk P">PP Kolodziejczyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masoudi, S" uniqKey="Masoudi S">S Masoudi</name></author><author><name sortKey="Rustaiyan, A" uniqKey="Rustaiyan A">A Rustaiyan</name></author><author><name sortKey="Vahedi, M" uniqKey="Vahedi M">M Vahedi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Habibi, Z" uniqKey="Habibi Z">Z Habibi</name></author><author><name sortKey="Ghanian, S" uniqKey="Ghanian S">S Ghanian</name></author><author><name sortKey="Ghasemi, S" uniqKey="Ghasemi S">S Ghasemi</name></author><author><name sortKey="Yousefi, M" uniqKey="Yousefi M">M Yousefi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shafaghat, A" uniqKey="Shafaghat A">A Shafaghat</name></author><author><name sortKey="Noormohammadi, Y" uniqKey="Noormohammadi Y">Y Noormohammadi</name></author><author><name sortKey="Zaifizadeh, M" uniqKey="Zaifizadeh M">M Zaifizadeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yap, Psx" uniqKey="Yap P">PSX Yap</name></author><author><name sortKey="Yiap, Bc" uniqKey="Yiap B">BC Yiap</name></author><author><name sortKey="Ping, Hc" uniqKey="Ping H">HC Ping</name></author><author><name sortKey="Lim, Sh" uniqKey="Lim S">SH Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kon, Kv" uniqKey="Kon K">KV Kon</name></author><author><name sortKey="Rai, Mk" uniqKey="Rai M">MK Rai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nelson, Rr" uniqKey="Nelson R">RR Nelson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doran, Al" uniqKey="Doran A">AL Doran</name></author><author><name sortKey="Morden, We" uniqKey="Morden W">WE Morden</name></author><author><name sortKey="Dunn, K" uniqKey="Dunn K">K Dunn</name></author><author><name sortKey="Edwards Jones, V" uniqKey="Edwards Jones V">V Edwards-Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Da Silva, Ac" uniqKey="Da Silva A">AC da Silva</name></author><author><name sortKey="Lopes, Pm" uniqKey="Lopes P">PM Lopes</name></author><author><name sortKey="De Azevedo, Mm" uniqKey="De Azevedo M">MM de Azevedo</name></author><author><name sortKey="Costa, Dc" uniqKey="Costa D">DC Costa</name></author><author><name sortKey="Alviano, Cs" uniqKey="Alviano C">CS Alviano</name></author><author><name sortKey="Alviano, Ds" uniqKey="Alviano D">DS Alviano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Acikgoz, Zc" uniqKey="Acikgoz Z">ZC Acikgoz</name></author><author><name sortKey="Gocer, S" uniqKey="Gocer S">S Gocer</name></author><author><name sortKey="Tuncer, S" uniqKey="Tuncer S">S Tuncer</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Yang, Chang" sort="Yang, Chang" uniqKey="Yang C" first="Chang" last="Yang">Chang Yang</name></noRegion><name sortKey="Feng, Yan" sort="Feng, Yan" uniqKey="Feng Y" first="Yan" last="Feng">Yan Feng</name><name sortKey="Hu, Dong Hui" sort="Hu, Dong Hui" uniqKey="Hu D" first="Dong-Hui" last="Hu">Dong-Hui Hu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000959 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000959 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4581751
|texte= Essential oil of Artemisia vestita exhibits potent in vitro and in vivo antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26259564" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV1
| This area was generated with Dilib version V0.6.33. |  |