Is the ferret a suitable species for studying perinatal brain injury?
Identifieur interne : 000950 ( Main/Exploration ); précédent : 000949; suivant : 000951Is the ferret a suitable species for studying perinatal brain injury?
Auteurs : Kristen Empie ; Vijayeta Rangarajan ; Sandra E. JuulSource :
- International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience [ 0736-5748 ] ; 2015.
Abstract
Complications of prematurity often disrupt normal brain development
and/or cause direct damage to the developing brain, resulting in poor
neurodevelopmental outcomes. Physiologically relevant animal models of perinatal
brain injury can advance our understanding of these influences and thereby
provide opportunities to develop therapies and improve long-term outcomes. While
there are advantages to currently available small animal models, there are also
significant drawbacks that have limited translation of research findings to
humans. Large animal models such as newborn pig, sheep and nonhuman primates
have complex brain development more similar to humans, but these animals are
expensive, and developmental testing of sheep and piglets is limited. Ferrets
(
Url:
DOI: 10.1016/j.ijdevneu.2015.06.005
PubMed: 26102988
PubMed Central: 4793918
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000521
- to stream Pmc, to step Curation: 000521
- to stream Pmc, to step Checkpoint: 000342
- to stream Ncbi, to step Merge: 000468
- to stream Ncbi, to step Curation: 000468
- to stream Ncbi, to step Checkpoint: 000468
- to stream Main, to step Merge: 000952
- to stream Main, to step Curation: 000950
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is the ferret a suitable species for studying perinatal brain
injury?</title><author><name sortKey="Empie, Kristen" sort="Empie, Kristen" uniqKey="Empie K" first="Kristen" last="Empie">Kristen Empie</name></author><author><name sortKey="Rangarajan, Vijayeta" sort="Rangarajan, Vijayeta" uniqKey="Rangarajan V" first="Vijayeta" last="Rangarajan">Vijayeta Rangarajan</name></author><author><name sortKey="Juul, Sandra E" sort="Juul, Sandra E" uniqKey="Juul S" first="Sandra E." last="Juul">Sandra E. Juul</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26102988</idno><idno type="pmc">4793918</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793918</idno><idno type="RBID">PMC:4793918</idno><idno type="doi">10.1016/j.ijdevneu.2015.06.005</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000521</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000521</idno><idno type="wicri:Area/Pmc/Curation">000521</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000521</idno><idno type="wicri:Area/Pmc/Checkpoint">000342</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000342</idno><idno type="wicri:Area/Ncbi/Merge">000468</idno><idno type="wicri:Area/Ncbi/Curation">000468</idno><idno type="wicri:Area/Ncbi/Checkpoint">000468</idno><idno type="wicri:doubleKey">0736-5748:2015:Empie K:is:the:ferret</idno><idno type="wicri:Area/Main/Merge">000952</idno><idno type="wicri:Area/Main/Curation">000950</idno><idno type="wicri:Area/Main/Exploration">000950</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Is the ferret a suitable species for studying perinatal brain
injury?</title><author><name sortKey="Empie, Kristen" sort="Empie, Kristen" uniqKey="Empie K" first="Kristen" last="Empie">Kristen Empie</name></author><author><name sortKey="Rangarajan, Vijayeta" sort="Rangarajan, Vijayeta" uniqKey="Rangarajan V" first="Vijayeta" last="Rangarajan">Vijayeta Rangarajan</name></author><author><name sortKey="Juul, Sandra E" sort="Juul, Sandra E" uniqKey="Juul S" first="Sandra E." last="Juul">Sandra E. Juul</name></author></analytic><series><title level="j">International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience</title><idno type="ISSN">0736-5748</idno><idno type="eISSN">1873-474X</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Complications of prematurity often disrupt normal brain development
and/or cause direct damage to the developing brain, resulting in poor
neurodevelopmental outcomes. Physiologically relevant animal models of perinatal
brain injury can advance our understanding of these influences and thereby
provide opportunities to develop therapies and improve long-term outcomes. While
there are advantages to currently available small animal models, there are also
significant drawbacks that have limited translation of research findings to
humans. Large animal models such as newborn pig, sheep and nonhuman primates
have complex brain development more similar to humans, but these animals are
expensive, and developmental testing of sheep and piglets is limited. Ferrets
(<italic>Mustela putorius furo)</italic> are born lissencephalic and undergo
postnatal cortical folding to form complex gyrencephalic brains. This review
examines whether ferrets might provide a novel intermediate animal model of
neonatal brain disease that has the benefit of a gyrified, altricial brain in a
small animal. It summarizes attributes of ferret brain growth and development
that make it an appealing animal in which to model perinatal brain injury. We
postulate that because of their innate characteristics, ferrets have great
potential in neonatal neurodevelopmental studies.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Empie, Kristen" sort="Empie, Kristen" uniqKey="Empie K" first="Kristen" last="Empie">Kristen Empie</name><name sortKey="Juul, Sandra E" sort="Juul, Sandra E" uniqKey="Juul S" first="Sandra E." last="Juul">Sandra E. Juul</name><name sortKey="Rangarajan, Vijayeta" sort="Rangarajan, Vijayeta" uniqKey="Rangarajan V" first="Vijayeta" last="Rangarajan">Vijayeta Rangarajan</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000950 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000950 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4793918
|texte= Is the ferret a suitable species for studying perinatal brain
injury?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26102988" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV1
| This area was generated with Dilib version V0.6.33. |  |