Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection
Identifieur interne : 000860 ( Main/Exploration ); précédent : 000859; suivant : 000861Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection
Auteurs : Madhavan Nair [États-Unis] ; Vidya Sagar [États-Unis] ; Sudheesh Pilakka-Kanthikeel [États-Unis]Source :
- Scientific Reports [ 2045-2322 ] ; 2016.
Abstract
Interplay between lncRNAs and mRNAs is rapidly emerging as a key epigenetic mechanism in controlling various cell functions. HIV can actively infect and/or can persist latently for years by manipulating host epigenetics; however, its molecular essence remains undiscovered in entirety. Here for the first time, we delineate the influence of HIV on global lncRNAs expression in monocytic cells lines. Our analysis revealed the expression modulation of nearly 1060 such lncRNAs which are associated with differentially expressed mRNAs in active and latent infection. This suggests a greater role of lncRNAs in regulating transcriptional and post-transcriptional gene expression during HIV infection. The differentially expressed mRNAs were involved in several different biological pathways where immunological networks were most enriched. Importantly, we discovered that HIV induces expression reversal of more than 150 lncRNAs between its active and latent infection. Also, hundreds of unique lncRNAs were identified in both infection conditions. The pathology specific “gene-expression reversal” and “on-and-off” switching of lncRNAs and associated mRNAs may lead to establish the relationship between active and HIV infection.
Url:
DOI: 10.1038/srep34862
PubMed: 27756902
PubMed Central: 5069461
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000066
- to stream Pmc, to step Curation: 000066
- to stream Pmc, to step Checkpoint: 000271
- to stream Ncbi, to step Merge: 000580
- to stream Ncbi, to step Curation: 000580
- to stream Ncbi, to step Checkpoint: 000580
- to stream Main, to step Merge: 000862
- to stream Main, to step Curation: 000860
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection</title>
<author><name sortKey="Nair, Madhavan" sort="Nair, Madhavan" uniqKey="Nair M" first="Madhavan" last="Nair">Madhavan Nair</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sagar, Vidya" sort="Sagar, Vidya" uniqKey="Sagar V" first="Vidya" last="Sagar">Vidya Sagar</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pilakka Kanthikeel, Sudheesh" sort="Pilakka Kanthikeel, Sudheesh" uniqKey="Pilakka Kanthikeel S" first="Sudheesh" last="Pilakka-Kanthikeel">Sudheesh Pilakka-Kanthikeel</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27756902</idno>
<idno type="pmc">5069461</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069461</idno>
<idno type="RBID">PMC:5069461</idno>
<idno type="doi">10.1038/srep34862</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000066</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000066</idno>
<idno type="wicri:Area/Pmc/Curation">000066</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000066</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000271</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000271</idno>
<idno type="wicri:Area/Ncbi/Merge">000580</idno>
<idno type="wicri:Area/Ncbi/Curation">000580</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000580</idno>
<idno type="wicri:Area/Main/Merge">000862</idno>
<idno type="wicri:Area/Main/Curation">000860</idno>
<idno type="wicri:Area/Main/Exploration">000860</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection</title>
<author><name sortKey="Nair, Madhavan" sort="Nair, Madhavan" uniqKey="Nair M" first="Madhavan" last="Nair">Madhavan Nair</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sagar, Vidya" sort="Sagar, Vidya" uniqKey="Sagar V" first="Vidya" last="Sagar">Vidya Sagar</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pilakka Kanthikeel, Sudheesh" sort="Pilakka Kanthikeel, Sudheesh" uniqKey="Pilakka Kanthikeel S" first="Sudheesh" last="Pilakka-Kanthikeel">Sudheesh Pilakka-Kanthikeel</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Immunology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Institute of Neuro-Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University</institution>
, Miami, FL-33199,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Scientific Reports</title>
<idno type="eISSN">2045-2322</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Interplay between lncRNAs and mRNAs is rapidly emerging as a key epigenetic mechanism in controlling various cell functions. HIV can actively infect and/or can persist latently for years by manipulating host epigenetics; however, its molecular essence remains undiscovered in entirety. Here for the first time, we delineate the influence of HIV on global lncRNAs expression in monocytic cells lines. Our analysis revealed the expression modulation of nearly 1060 such lncRNAs which are associated with differentially expressed mRNAs in active and latent infection. This suggests a greater role of lncRNAs in regulating transcriptional and post-transcriptional gene expression during HIV infection. The differentially expressed mRNAs were involved in several different biological pathways where immunological networks were most enriched. Importantly, we discovered that HIV induces expression reversal of more than 150 lncRNAs between its active and latent infection. Also, hundreds of unique lncRNAs were identified in both infection conditions. The pathology specific “gene-expression reversal” and “on-and-off” switching of lncRNAs and associated mRNAs may lead to establish the relationship between active and HIV infection.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chun, T W" uniqKey="Chun T">T. W. Chun</name>
</author>
<author><name sortKey="Fauci, A S" uniqKey="Fauci A">A. S. Fauci</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hellmuth, J" uniqKey="Hellmuth J">J. Hellmuth</name>
</author>
<author><name sortKey="Valcour, V" uniqKey="Valcour V">V. Valcour</name>
</author>
<author><name sortKey="Spudich, S" uniqKey="Spudich S">S. Spudich</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sacha, J B" uniqKey="Sacha J">J. B. Sacha</name>
</author>
<author><name sortKey="Ndhlovu, L C" uniqKey="Ndhlovu L">L. C. Ndhlovu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stevenson, M C R O I" uniqKey="Stevenson M">M. C. R. O. I. Stevenson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wong, J K" uniqKey="Wong J">J. K. Wong</name>
</author>
<author><name sortKey="Yukl, S A" uniqKey="Yukl S">S. A. Yukl</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eisele, E" uniqKey="Eisele E">E. Eisele</name>
</author>
<author><name sortKey="Siliciano, R F" uniqKey="Siliciano R">R. F. Siliciano</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Burdo, T H" uniqKey="Burdo T">T. H. Burdo</name>
</author>
<author><name sortKey="Lackner, A" uniqKey="Lackner A">A. Lackner</name>
</author>
<author><name sortKey="Williams, K C" uniqKey="Williams K">K. C. Williams</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mbonye, U" uniqKey="Mbonye U">U. Mbonye</name>
</author>
<author><name sortKey="Karn, J" uniqKey="Karn J">J. Karn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mbonye, U" uniqKey="Mbonye U">U. Mbonye</name>
</author>
<author><name sortKey="Karn, J" uniqKey="Karn J">J. Karn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Lint, C" uniqKey="Van Lint C">C. Van Lint</name>
</author>
<author><name sortKey="Bouchat, S" uniqKey="Bouchat S">S. Bouchat</name>
</author>
<author><name sortKey="Marcello, A" uniqKey="Marcello A">A. Marcello</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Blazkova, J" uniqKey="Blazkova J">J. Blazkova</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kumar, A" uniqKey="Kumar A">A. Kumar</name>
</author>
<author><name sortKey="Darcis, G" uniqKey="Darcis G">G. Darcis</name>
</author>
<author><name sortKey="Van Lint, C" uniqKey="Van Lint C">C. Van Lint</name>
</author>
<author><name sortKey="Herbein, G" uniqKey="Herbein G">G. Herbein</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Park, J" uniqKey="Park J">J. Park</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Qu, X" uniqKey="Qu X">X. Qu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barichievy, S" uniqKey="Barichievy S">S. Barichievy</name>
</author>
<author><name sortKey="Naidoo, J" uniqKey="Naidoo J">J. Naidoo</name>
</author>
<author><name sortKey="Mhlanga, M M" uniqKey="Mhlanga M">M. M. Mhlanga</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Groen, J N" uniqKey="Groen J">J. N. Groen</name>
</author>
<author><name sortKey="Morris, K V" uniqKey="Morris K">K. V. Morris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q. Zhang</name>
</author>
<author><name sortKey="Jeang, K T" uniqKey="Jeang K">K. T. Jeang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bohmdorfer, G" uniqKey="Bohmdorfer G">G. Bohmdorfer</name>
</author>
<author><name sortKey="Wierzbicki, A T" uniqKey="Wierzbicki A">A. T. Wierzbicki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kornienko, A E" uniqKey="Kornienko A">A. E. Kornienko</name>
</author>
<author><name sortKey="Guenzl, P M" uniqKey="Guenzl P">P. M. Guenzl</name>
</author>
<author><name sortKey="Barlow, D P" uniqKey="Barlow D">D. P. Barlow</name>
</author>
<author><name sortKey="Pauler, F M" uniqKey="Pauler F">F. M. Pauler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barriocanal, M" uniqKey="Barriocanal M">M. Barriocanal</name>
</author>
<author><name sortKey="Carnero, E" uniqKey="Carnero E">E. Carnero</name>
</author>
<author><name sortKey="Segura, V" uniqKey="Segura V">V. Segura</name>
</author>
<author><name sortKey="Fortes, P" uniqKey="Fortes P">P. Fortes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Imam, H" uniqKey="Imam H">H. Imam</name>
</author>
<author><name sortKey="Bano, A S" uniqKey="Bano A">A. S. Bano</name>
</author>
<author><name sortKey="Patel, P" uniqKey="Patel P">P. Patel</name>
</author>
<author><name sortKey="Holla, P" uniqKey="Holla P">P. Holla</name>
</author>
<author><name sortKey="Jameel, S" uniqKey="Jameel S">S. Jameel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q. Zhang</name>
</author>
<author><name sortKey="Chen, C Y" uniqKey="Chen C">C. Y. Chen</name>
</author>
<author><name sortKey="Yedavalli, V S" uniqKey="Yedavalli V">V. S. Yedavalli</name>
</author>
<author><name sortKey="Jeang, K T" uniqKey="Jeang K">K. T. Jeang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kumar, A" uniqKey="Kumar A">A. Kumar</name>
</author>
<author><name sortKey="Abbas, W" uniqKey="Abbas W">W. Abbas</name>
</author>
<author><name sortKey="Herbein, G" uniqKey="Herbein G">G. Herbein</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saayman, S" uniqKey="Saayman S">S. Saayman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barton, K M" uniqKey="Barton K">K. M. Barton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Archin, N M" uniqKey="Archin N">N. M. Archin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saiyed, Z M" uniqKey="Saiyed Z">Z. M. Saiyed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Klase, Z" uniqKey="Klase Z">Z. Klase</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bachis, A" uniqKey="Bachis A">A. Bachis</name>
</author>
<author><name sortKey="Avdoshina, V" uniqKey="Avdoshina V">V. Avdoshina</name>
</author>
<author><name sortKey="Zecca, L" uniqKey="Zecca L">L. Zecca</name>
</author>
<author><name sortKey="Parsadanian, M" uniqKey="Parsadanian M">M. Parsadanian</name>
</author>
<author><name sortKey="Mocchetti, I" uniqKey="Mocchetti I">I. Mocchetti</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guendel, I" uniqKey="Guendel I">I. Guendel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhu, X" uniqKey="Zhu X">X. Zhu</name>
</author>
<author><name sortKey="Need, A C" uniqKey="Need A">A. C. Need</name>
</author>
<author><name sortKey="Petrovski, S" uniqKey="Petrovski S">S. Petrovski</name>
</author>
<author><name sortKey="Goldstein, D B" uniqKey="Goldstein D">D. B. Goldstein</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mitsui, J" uniqKey="Mitsui J">J. Mitsui</name>
</author>
<author><name sortKey="Tsuji, S" uniqKey="Tsuji S">S. Tsuji</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kitchen, R R" uniqKey="Kitchen R">R. R. Kitchen</name>
</author>
<author><name sortKey="Rozowsky, J S" uniqKey="Rozowsky J">J. S. Rozowsky</name>
</author>
<author><name sortKey="Gerstein, M B" uniqKey="Gerstein M">M. B. Gerstein</name>
</author>
<author><name sortKey="Nairn, A C" uniqKey="Nairn A">A. C. Nairn</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><country name="États-Unis"><noRegion><name sortKey="Nair, Madhavan" sort="Nair, Madhavan" uniqKey="Nair M" first="Madhavan" last="Nair">Madhavan Nair</name>
</noRegion>
<name sortKey="Nair, Madhavan" sort="Nair, Madhavan" uniqKey="Nair M" first="Madhavan" last="Nair">Madhavan Nair</name>
<name sortKey="Nair, Madhavan" sort="Nair, Madhavan" uniqKey="Nair M" first="Madhavan" last="Nair">Madhavan Nair</name>
<name sortKey="Pilakka Kanthikeel, Sudheesh" sort="Pilakka Kanthikeel, Sudheesh" uniqKey="Pilakka Kanthikeel S" first="Sudheesh" last="Pilakka-Kanthikeel">Sudheesh Pilakka-Kanthikeel</name>
<name sortKey="Pilakka Kanthikeel, Sudheesh" sort="Pilakka Kanthikeel, Sudheesh" uniqKey="Pilakka Kanthikeel S" first="Sudheesh" last="Pilakka-Kanthikeel">Sudheesh Pilakka-Kanthikeel</name>
<name sortKey="Pilakka Kanthikeel, Sudheesh" sort="Pilakka Kanthikeel, Sudheesh" uniqKey="Pilakka Kanthikeel S" first="Sudheesh" last="Pilakka-Kanthikeel">Sudheesh Pilakka-Kanthikeel</name>
<name sortKey="Sagar, Vidya" sort="Sagar, Vidya" uniqKey="Sagar V" first="Vidya" last="Sagar">Vidya Sagar</name>
<name sortKey="Sagar, Vidya" sort="Sagar, Vidya" uniqKey="Sagar V" first="Vidya" last="Sagar">Vidya Sagar</name>
<name sortKey="Sagar, Vidya" sort="Sagar, Vidya" uniqKey="Sagar V" first="Vidya" last="Sagar">Vidya Sagar</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000860 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000860 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:5069461 |texte= Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27756902" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a CovidV1
This area was generated with Dilib version V0.6.33. |