Legume Lectins: Proteins with Diverse Applications
Identifieur interne : 000780 ( Main/Exploration ); précédent : 000779; suivant : 000781Legume Lectins: Proteins with Diverse Applications
Auteurs : Irlanda Lagarda-Diaz ; Ana Maria Guzman-Partida ; Luz Vazquez-MorenoSource :
- International Journal of Molecular Sciences [ 1422-0067 ] ; 2017.
Abstract
Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets.
Url:
DOI: 10.3390/ijms18061242
PubMed: 28604616
PubMed Central: 5486065
Affiliations:
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Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Sharon, N" uniqKey="Sharon N">N. Sharon</name></author><author><name sortKey="Lis, H" uniqKey="Lis H">H. 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Lei</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Guzman Partida, Ana Maria" sort="Guzman Partida, Ana Maria" uniqKey="Guzman Partida A" first="Ana Maria" last="Guzman-Partida">Ana Maria Guzman-Partida</name><name sortKey="Lagarda Diaz, Irlanda" sort="Lagarda Diaz, Irlanda" uniqKey="Lagarda Diaz I" first="Irlanda" last="Lagarda-Diaz">Irlanda Lagarda-Diaz</name><name sortKey="Vazquez Moreno, Luz" sort="Vazquez Moreno, Luz" uniqKey="Vazquez Moreno L" first="Luz" last="Vazquez-Moreno">Luz Vazquez-Moreno</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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