Antiviral Substances
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Auteurs : Kenneth L. Rinehart [États-Unis] ; Lois S. Shield [États-Unis] ; Martha Cohen-Parsons [États-Unis]Source :
Abstract
Abstract: Even today, antiviral drugs are a rarity (Becker, 1976, 1983; Rothschild et al., 1978; R. T. Walker et al., 1979; Collier and Oxford, 1980; De Clercq and Walker, 1984; Mandell et al., 1985; Rinehart, 1992): acyclovir is a notable success in reducing the severity of genital herpes infections, and newer analogues are under development; azidothymidine (AZT) is widely employed to extend the lifetime of AIDS sufferers, while other compounds with anti-AIDS potential are under investigation; vidarabine is approved for the treatment of idoxuridine-and acyclovir-resistant infections; ribavirin is an intranasal inhalant effective against respiratory syncitial virus (Stephen et al., 1980); amantidine has been used for many years in treating some forms of influenza (Davies et al., 1964). Even fewer antiviral agents were available in the 1970s when we began our systematic surveys designed to assess the bioactivity of marine organisms.
Url:
DOI: 10.1007/978-1-4899-2391-2_8
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