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Impact of Ischemic Heart Disease on Early Access Failure in Nondiabetic Hemodialysis Patients

Identifieur interne : 000990 ( Istex/Corpus ); précédent : 000989; suivant : 000991

Impact of Ischemic Heart Disease on Early Access Failure in Nondiabetic Hemodialysis Patients

Auteurs : Y. O. Kim ; S. J. Shin ; Y. S. Shin ; S. H. Lee ; S. A. Yoon ; Y. S. Kim ; Y. S. Chang ; B. K. Bang

Source :

RBID : ISTEX:A3C6AC19F31ADD35F197F0C6B689CC133F3BD679

Abstract

Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428). Objective:  This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients. Methods:  This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF. Results:  The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p < 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF. Conclusion:  This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.

Url:
DOI: 10.1111/j.1492-7535.2004.0085d.x

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ISTEX:A3C6AC19F31ADD35F197F0C6B689CC133F3BD679

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<div type="abstract" xml:lang="en">Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428). Objective:  This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients. Methods:  This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF. Results:  The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p < 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF. Conclusion:  This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.</div>
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<author>
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<name>Y.o. Kim</name>
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<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
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<json:item>
<name>S.j. Shin</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>Y.s. Shin</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>S.h. Lee</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>S.a. Yoon</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>Y.s. Kim</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>Y.s. Chang</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
<json:item>
<name>B.k. Bang</name>
<affiliations>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string>
</affiliations>
</json:item>
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<json:string>HDI085D</json:string>
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<json:string>abstract</json:string>
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<abstract>Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428). Objective:  This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients. Methods:  This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF. Results:  The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p > 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF. Conclusion:  This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.</abstract>
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<title>Impact of Ischemic Heart Disease on Early Access Failure in Nondiabetic Hemodialysis Patients</title>
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<title>Hemodialysis International</title>
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<doi>
<json:string>10.1111/(ISSN)1542-4758</json:string>
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<json:string>1492-7535</json:string>
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<json:string>1542-4758</json:string>
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<json:string>HDI</json:string>
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<volume>8</volume>
<issue>1</issue>
<pages>
<first>79</first>
<last>79</last>
<total>100</total>
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<json:string>and US HD</json:string>
<json:string>Childrens Hospital, University of Texas Medical Branch, Galveston, TX</json:string>
<json:string>Abstracts Hemodialysis International</json:string>
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<json:string>Department of Nephrology H</json:string>
<json:string>Division of Pediatric Nephrology</json:string>
<json:string>Baskent University</json:string>
<json:string>General Hospital, Athens, Greece</json:string>
<json:string>Consiglio</json:string>
<json:string>The Jos University</json:string>
<json:string>University of Texas Health Science Center, San Antonio</json:string>
<json:string>Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden</json:string>
<json:string>University Faculty of Medicine</json:string>
<json:string>Virginia Commonwealth University</json:string>
<json:string>Medical University</json:string>
<json:string>Society for Hemodialysis</json:string>
<json:string>Shonan Institute of Technology, Fujisawa</json:string>
<json:string>Department of Chemical Pathology</json:string>
<json:string>Louisiana State University</json:string>
<json:string>Department of Pediatric Nephrology, University Children</json:string>
<json:string>Department of Nephrology, Hospital Universitario</json:string>
<json:string>University Hospitals of Cleveland</json:string>
<json:string>Division of Molecular Medicine</json:string>
<json:string>Department of Internal Medicine, University of Turin, Turin, Italy</json:string>
<json:string>Luke’s Hospital, Chester</json:string>
<json:string>Hospital for Sick Children, Toronto, Ontario, Canada</json:string>
<json:string>Department of Internal Medicine, NHIC Ilsan Hospital, Goyang, Gyeonggi, Korea</json:string>
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<json:string>Kingston General Hospital, Kingston, Ontario, Canada</json:string>
<json:string>Department of Biochemistry</json:string>
<json:string>Turkey Vascular</json:string>
<json:string>Mercy Hospital, Kansas City, MO</json:string>
<json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea</json:string>
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<json:string>Lamentin Hospital, Martinique</json:string>
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<json:string>Department of Internal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt</json:string>
<json:string>Michael’s Hospital Infection Control Department and Health, Canada</json:string>
<json:string>Central Laboratory of Immunology and Microbiology</json:string>
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<json:string>G. Sakellariou</json:string>
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<p>Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428).</p>
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<hi rend="bold">Objective: </hi>
This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients.</p>
<p>
<hi rend="bold">Methods: </hi>
This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF.</p>
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<hi rend="bold">Results: </hi>
The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p < 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF.</p>
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This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.</p>
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<title type="main">Impact of Ischemic Heart Disease on Early Access Failure in Nondiabetic Hemodialysis Patients</title>
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<p>Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428).</p>
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<b>Objective: </b>
This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients.</p>
<p>
<b>Methods: </b>
This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF.</p>
<p>
<b>Results: </b>
The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p < 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF.</p>
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<b>Conclusion: </b>
This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.</p>
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<abstract lang="en">Atherosclerotic lesion of coronary artery frequently accompanies intimal hyperplasia of radial artery. We have reported that the lesion of radial artery (intimal hyperplasia) in hemodialysis (HD) patients is associated with early access failure (EAF) as well as ischemic heart disease (IHD) (Am J Kidney Dis. 2003; 41: 422–428). Objective:  This study was designed to determine the impact of IHD on the EAF in nondiabetic HD patients. Methods:  This study enrolled 125 nondiabetic HD patients who received radiocephalic arteriovenous fistula operation for the first time. We evaluated IHD before the operation through clinical symptoms and electrocardiography and then investigated EAF within 1 year after the operation. We analyzed the access patency rates between the patients with and without IHD, using Kaplan–Meier method and log‐rank test. Multiple regression analysis was performed to identify independent risk factors of the EAF. Results:  The mean age of the patients was 48 ± 14 years, and the number of females was 54 (43.2%). Of the total 125 patients, 19 patients (15.4%) had IHD before the operation. The EAF developed in 23 patients (18.4%) within 1 years after the operation. The access patency rate in the patients with IHD was lower than that in the patients without IHD (39.7 vs. 88.3%, p < 0.001). IHD and old age were independent risk factors of the EAF in nondiabetic HD patients. But sex, smoking history, hypertension, and the levels of hemoglobin, serum creatinine, albumin, and total cholesterol checked before the operation were not associated with the EAF. Conclusion:  This study suggests that IHD is closely associated with EAF in nondiabetic HD patients.</abstract>
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