Antigenic relationships amongst coronaviruses
Identifieur interne : 000732 ( Istex/Corpus ); précédent : 000731; suivant : 000733Antigenic relationships amongst coronaviruses
Auteurs : A. F. BradburneSource :
- Archiv für die gesamte Virusforschung [ 0003-9012 ] ; 1970-09-01.
English descriptors
- Teeft :
- Antibody titres, Antigen, Antigenic, Antigenic relationships, Antiserum, Ascitic, Ascitic fluid, Ascitic fluids, Avian, Bradburne, Bradburne antigenic relationships, Bronchitis, Bronchitis virus, Chicken erythrocytes, Complement fixation, Complement fixation tests, Convalescent sera, Coombe road, Coronavirus, Coronavirus antigens, Coronavirus group, Coronaviruses, Cytopathic effects, Embryo lung, Fixation, Harvard hospital, Heterologous reactions, Human sera, Hyperimmune, Hyperimmune animal sera, Hyperimmune antisera, Hyperimmune ascitic fluids, Hyperimmune sera, Hyperimmune serum, Infectious bronchitis virus, Intramuscular injection, Mhva, Mouse, Mouse brain, Mouse hepatitis, Mouse hepatitis virus, Mouse hepatitis viruses, Mouse neutralization tests, Neutralization, Neutralization constants, Neutralization tests, Neutralizing antibody, Neutralizing antibody titres, Organ cultures, Overnight fixation, Plaque, Plaque reduction tests, Precipitin lines, Roller tube cultures, Room temperature, Serum, Serum pairs, Such sera, Suckling, Suckling mice, Suckling mouse brain, Tissue culture neutralization tests, Tissue culture pools, Titre, Tracheal organ cultures, Tube neutralization tests, Virus, Virus infection, Volunteer sera.
Abstract
Summary: Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV3) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations.
Url:
DOI: 10.1007/BF01253769
Links to Exploration step
ISTEX:16130AA0F0EF7310B7E8F7EE8203651021AC388DLe document en format XML
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Bradburne</name><affiliation><mods:affiliation>Common Cold Unit, Harvard Hospital, Coombe Road, Salisbury, Wiltshire, England</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Archiv für die gesamte Virusforschung</title><title level="j" type="abbrev">Archiv f Virusforschung</title><idno type="ISSN">0003-9012</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1970-09-01">1970-09-01</date><biblScope unit="volume">31</biblScope><biblScope unit="issue">3-4</biblScope><biblScope unit="page" from="352">352</biblScope><biblScope unit="page" to="364">364</biblScope></imprint><idno type="ISSN">0003-9012</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0003-9012</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antibody titres</term><term>Antigen</term><term>Antigenic</term><term>Antigenic relationships</term><term>Antiserum</term><term>Ascitic</term><term>Ascitic fluid</term><term>Ascitic fluids</term><term>Avian</term><term>Bradburne</term><term>Bradburne antigenic relationships</term><term>Bronchitis</term><term>Bronchitis virus</term><term>Chicken erythrocytes</term><term>Complement fixation</term><term>Complement fixation tests</term><term>Convalescent sera</term><term>Coombe road</term><term>Coronavirus</term><term>Coronavirus antigens</term><term>Coronavirus group</term><term>Coronaviruses</term><term>Cytopathic effects</term><term>Embryo lung</term><term>Fixation</term><term>Harvard hospital</term><term>Heterologous reactions</term><term>Human sera</term><term>Hyperimmune</term><term>Hyperimmune animal sera</term><term>Hyperimmune antisera</term><term>Hyperimmune ascitic fluids</term><term>Hyperimmune sera</term><term>Hyperimmune serum</term><term>Infectious bronchitis virus</term><term>Intramuscular injection</term><term>Mhva</term><term>Mouse</term><term>Mouse brain</term><term>Mouse hepatitis</term><term>Mouse hepatitis virus</term><term>Mouse hepatitis viruses</term><term>Mouse neutralization tests</term><term>Neutralization</term><term>Neutralization constants</term><term>Neutralization tests</term><term>Neutralizing antibody</term><term>Neutralizing antibody titres</term><term>Organ cultures</term><term>Overnight fixation</term><term>Plaque</term><term>Plaque reduction tests</term><term>Precipitin lines</term><term>Roller tube cultures</term><term>Room temperature</term><term>Serum</term><term>Serum pairs</term><term>Such sera</term><term>Suckling</term><term>Suckling mice</term><term>Suckling mouse brain</term><term>Tissue culture neutralization tests</term><term>Tissue culture pools</term><term>Titre</term><term>Tracheal organ cultures</term><term>Tube neutralization tests</term><term>Virus</term><term>Virus infection</term><term>Volunteer sera</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV3) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. 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Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV3) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. 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Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV<Subscript>3</Subscript>) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations.</Para></Abstract></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Antigenic relationships amongst coronaviruses</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Antigenic relationships amongst coronaviruses</title></titleInfo><name type="personal"><namePart type="given">A.</namePart><namePart type="given">F.</namePart><namePart type="family">Bradburne</namePart><affiliation>Common Cold Unit, Harvard Hospital, Coombe Road, Salisbury, Wiltshire, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">Vienna</placeTerm></place><dateCreated encoding="w3cdtf">1970-02-06</dateCreated><dateIssued encoding="w3cdtf">1970-09-01</dateIssued><copyrightDate encoding="w3cdtf">1970</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Summary: Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV3) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. 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