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Component-Based Modelling of RNA Structure Folding

Identifieur interne : 000561 ( Istex/Corpus ); précédent : 000560; suivant : 000562

Component-Based Modelling of RNA Structure Folding

Source :

Lecture Notes in Computer Science [ 0302-9743 ]

RBID : ISTEX:0AB3B3FF8AFE94A5D68EF120BA1B7F1618715371

Abstract

Abstract: RNA structure is fundamentally important for many biological processes. In the past decades, diverse structure prediction algorithms and tools were developed but due to missing descriptions in clearly defined modelling formalisms it’s difficult or even impossible to integrate them into larger system models. We present an RNA secondary structure folding model described in ml-Devs, a variant of the Devs formalism, which enables the hierarchical combination with other model components like RNA binding proteins. An example of transcriptional attenuation will be given where model components of RNA polymerase, the folding RNA molecule, and the translating ribosome play together in a composed dynamic model.

Url:

https://api.istex.fr/ark:/67375/HCB-498QDL34-4/fulltext.pdf

DOI: 10.1007/978-3-540-88562-7_8

Links to Exploration step

ISTEX:0AB3B3FF8AFE94A5D68EF120BA1B7F1618715371

Le document en format XML

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<p>RNA structure is fundamentally important for many biological processes. In the past decades, diverse structure prediction algorithms and tools were developed but due to missing descriptions in clearly defined modelling formalisms it’s difficult or even impossible to integrate them into larger system models. We present an RNA secondary structure folding model described in <hi rend="smallCaps">ml-Devs</hi>
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<ChapterTitle Language="En">Component-Based Modelling of RNA Structure Folding</ChapterTitle>
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<City>Rostock</City>
<Country>Germany</Country>
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<Para>RNA structure is fundamentally important for many biological processes. In the past decades, diverse structure prediction algorithms and tools were developed but due to missing descriptions in clearly defined modelling formalisms it’s difficult or even impossible to integrate them into larger system models. We present an RNA secondary structure folding model described in <Emphasis Type="SmallCaps">ml-Devs</Emphasis>
, a variant of the <Emphasis Type="SmallCaps">Devs</Emphasis>
 formalism, which enables the hierarchical combination with other model components like RNA binding proteins. An example of transcriptional attenuation will be given where model components of RNA polymerase, the folding RNA molecule, and the translating ribosome play together in a composed dynamic model.</Para>
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<Keyword>RNA folding</Keyword>
<Keyword>secondary structure</Keyword>
<Keyword>DEVS</Keyword>
<Keyword>model components</Keyword>
<Keyword>multi-level</Keyword>
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<abstract lang="en">Abstract: RNA structure is fundamentally important for many biological processes. In the past decades, diverse structure prediction algorithms and tools were developed but due to missing descriptions in clearly defined modelling formalisms it’s difficult or even impossible to integrate them into larger system models. We present an RNA secondary structure folding model described in ml-Devs, a variant of the Devs formalism, which enables the hierarchical combination with other model components like RNA binding proteins. An example of transcriptional attenuation will be given where model components of RNA polymerase, the folding RNA molecule, and the translating ribosome play together in a composed dynamic model.</abstract>
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Component-Based Modelling of RNA Structure Folding

Component-Based Modelling of RNA Structure Folding

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