Burden of respiratory viruses in patients with acute respiratory failure
Identifieur interne : 000409 ( Istex/Corpus ); précédent : 000408; suivant : 000410Burden of respiratory viruses in patients with acute respiratory failure
Auteurs : David Schnell ; Maud Gits-Muselli ; Emmanuel Canet ; Virginie Lemiale ; Benoît Schlemmer ; François Simon ; Elie Azoulay ; Jérôme LegoffSource :
- Journal of Medical Virology [ 0146-6615 ] ; 2014-07.
Abstract
Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/jmv.23760
Links to Exploration step
ISTEX:D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Burden of respiratory viruses in patients with acute respiratory failure</title><author><name sortKey="Schnell, David" sort="Schnell, David" uniqKey="Schnell D" first="David" last="Schnell">David Schnell</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence to: David Schnell, AP‐HP, Hôpital Saint‐Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France; Paris‐Diderot University, UFR de Médecine, 75010 Paris, France.E‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: david.schnell@sls.aphp.fr</mods:affiliation></affiliation></author><author><name sortKey="Gits Uselli, Maud" sort="Gits Uselli, Maud" uniqKey="Gits Uselli M" first="Maud" last="Gits-Muselli">Maud Gits-Muselli</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Canet, Emmanuel" sort="Canet, Emmanuel" uniqKey="Canet E" first="Emmanuel" last="Canet">Emmanuel Canet</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Lemiale, Virginie" sort="Lemiale, Virginie" uniqKey="Lemiale V" first="Virginie" last="Lemiale">Virginie Lemiale</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Schlemmer, Benoit" sort="Schlemmer, Benoit" uniqKey="Schlemmer B" first="Benoît" last="Schlemmer">Benoît Schlemmer</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Simon, Francois" sort="Simon, Francois" uniqKey="Simon F" first="François" last="Simon">François Simon</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Azoulay, Elie" sort="Azoulay, Elie" uniqKey="Azoulay E" first="Elie" last="Azoulay">Elie Azoulay</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Legoff, Jerome" sort="Legoff, Jerome" uniqKey="Legoff J" first="Jérôme" last="Legoff">Jérôme Legoff</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4</idno><date when="2014" year="2014">2014</date><idno type="doi">10.1002/jmv.23760</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000409</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000409</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Burden of respiratory viruses in patients with acute respiratory failure</title><author><name sortKey="Schnell, David" sort="Schnell, David" uniqKey="Schnell D" first="David" last="Schnell">David Schnell</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence to: David Schnell, AP‐HP, Hôpital Saint‐Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France; Paris‐Diderot University, UFR de Médecine, 75010 Paris, France.E‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: david.schnell@sls.aphp.fr</mods:affiliation></affiliation></author><author><name sortKey="Gits Uselli, Maud" sort="Gits Uselli, Maud" uniqKey="Gits Uselli M" first="Maud" last="Gits-Muselli">Maud Gits-Muselli</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Canet, Emmanuel" sort="Canet, Emmanuel" uniqKey="Canet E" first="Emmanuel" last="Canet">Emmanuel Canet</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Lemiale, Virginie" sort="Lemiale, Virginie" uniqKey="Lemiale V" first="Virginie" last="Lemiale">Virginie Lemiale</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Schlemmer, Benoit" sort="Schlemmer, Benoit" uniqKey="Schlemmer B" first="Benoît" last="Schlemmer">Benoît Schlemmer</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Simon, Francois" sort="Simon, Francois" uniqKey="Simon F" first="François" last="Simon">François Simon</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Azoulay, Elie" sort="Azoulay, Elie" uniqKey="Azoulay E" first="Elie" last="Azoulay">Elie Azoulay</name><affiliation><mods:affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Legoff, Jerome" sort="Legoff, Jerome" uniqKey="Legoff J" first="Jérôme" last="Legoff">Jérôme Legoff</name><affiliation><mods:affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="ISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><imprint><biblScope unit="vol">86</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1198">1198</biblScope><biblScope unit="page" to="1202">1202</biblScope><biblScope unit="page-count">5</biblScope><date type="published" when="2014-07">2014-07</date></imprint><idno type="ISSN">0146-6615</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0146-6615</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>multiplex</json:string><json:string>viral</json:string><json:string>assay</json:string><json:string>acute respiratory failure</json:string><json:string>multiplex molecular assay</json:string><json:string>obstructive</json:string><json:string>respiratory virus</json:string><json:string>rhinovirus</json:string><json:string>chronic obstructive pulmonary disease</json:string><json:string>acute exacerbation</json:string><json:string>hmpv</json:string><json:string>clin</json:string><json:string>intensive care unit</json:string><json:string>viral infection</json:string><json:string>asthma</json:string><json:string>parainfluenza virus</json:string><json:string>respiratory syncytial virus</json:string><json:string>human metapneumovirus</json:string><json:string>study patient</json:string><json:string>antibiotic</json:string><json:string>influenza</json:string><json:string>respiratory specimen</json:string><json:string>influenza virus</json:string><json:string>immunocompromised patient</json:string><json:string>more prone</json:string><json:string>exacerbation</json:string><json:string>atypical bacteria</json:string><json:string>odds ratio</json:string><json:string>bronchoalveolar lavage fluid</json:string><json:string>confidence interval</json:string><json:string>obstructive respiratory disease</json:string><json:string>interquartile range</json:string><json:string>intensive care unit admission</json:string><json:string>wiley periodical</json:string><json:string>positive molecular assay</json:string><json:string>virological screening</json:string><json:string>positive multiplex molecular assay</json:string><json:string>univariate analysis</json:string><json:string>present result</json:string><json:string>molecular assay</json:string><json:string>asymptomatic viral</json:string><json:string>other etiology</json:string><json:string>rapid detection</json:string><json:string>further investigation</json:string><json:string>rapid diagnosis</json:string><json:string>acute respiratory failure event</json:string><json:string>respiratory viral infection</json:string></teeft></keywords><author><json:item><name>David Schnell</name><affiliations><json:string>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</json:string><json:string>Paris‐Diderot University, UFR de Médecine, Paris, France</json:string><json:string>Correspondence to: David Schnell, AP‐HP, Hôpital Saint‐Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France; Paris‐Diderot University, UFR de Médecine, 75010 Paris, France.E‐mail:</json:string><json:string>E-mail: david.schnell@sls.aphp.fr</json:string></affiliations></json:item><json:item><name>Maud Gits‐Muselli</name><affiliations><json:string>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</json:string></affiliations></json:item><json:item><name>Emmanuel Canet</name><affiliations><json:string>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</json:string><json:string>Paris‐Diderot University, UFR de Médecine, Paris, France</json:string></affiliations></json:item><json:item><name>Virginie Lemiale</name><affiliations><json:string>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</json:string><json:string>Paris‐Diderot University, UFR de Médecine, Paris, France</json:string></affiliations></json:item><json:item><name>Benoît Schlemmer</name><affiliations><json:string>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</json:string><json:string>Paris‐Diderot University, UFR de Médecine, Paris, France</json:string></affiliations></json:item><json:item><name>François Simon</name><affiliations><json:string>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</json:string></affiliations></json:item><json:item><name>Elie Azoulay</name><affiliations><json:string>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</json:string><json:string>Paris‐Diderot University, UFR de Médecine, Paris, France</json:string></affiliations></json:item><json:item><name>Jérôme Legoff</name><affiliations><json:string>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>acute respiratory failure</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>pneumonia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>polymerase chain reaction assay</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>respiratory viruses</value></json:item></subject><articleId><json:string>JMV23760</json:string></articleId><arkIstex>ark:/67375/WNG-RR6CQZ98-J</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.</abstract><qualityIndicators><refBibsNative>true</refBibsNative><abstractWordCount>170</abstractWordCount><abstractCharCount>1235</abstractCharCount><keywordCount>4</keywordCount><score>6.639</score><pdfWordCount>2599</pdfWordCount><pdfCharCount>17616</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>5</pdfPageCount><pdfPageSize>593.972 x 792 pts</pdfPageSize><pdfWordsPerPage>520</pdfWordsPerPage><pdfText>true</pdfText></qualityIndicators><title>Burden of respiratory viruses in patients with acute respiratory failure</title><genre><json:string>article</json:string></genre><host><title>Journal of Medical Virology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1096-9071</json:string></doi><issn><json:string>0146-6615</json:string></issn><eissn><json:string>1096-9071</json:string></eissn><publisherId><json:string>JMV</json:string></publisherId><volume>86</volume><issue>7</issue><pages><first>1198</first><last>1202</last><total>5</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Research Article</value></json:item><json:item><value>Research Articles</value></json:item></subject></host><ark><json:string>ark:/67375/WNG-RR6CQZ98-J</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - virology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - biomedical research</json:string><json:string>3 - virology</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Infectious Diseases</json:string><json:string>1 - Life Sciences</json:string><json:string>2 - Immunology and Microbiology</json:string><json:string>3 - Virology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>2014</publicationDate><copyrightDate>2014</copyrightDate><doi><json:string>10.1002/jmv.23760</json:string></doi><id>D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Burden of respiratory viruses in patients with acute respiratory failure</title><title level="a" type="short">Respiratory Viruses Burden in ICU Patients</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher ref="https://scientific-publisher.data.istex.fr/ark:/67375/H02-QW5Q88H5-V">Wiley Publishing Ltd</publisher><availability><licence>© 2013 Wiley Periodicals, Inc.</licence></availability><date type="published" when="2014-07"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Burden of respiratory viruses in patients with acute respiratory failure</title><title level="a" type="short">Respiratory Viruses Burden in ICU Patients</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">David</forename><surname>Schnell</surname></persName><affiliation><orgName type="division">Medical ICU</orgName><orgName type="institution">AP‐HP, Hôpital Saint‐Louis</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Maud</forename><surname>Gits‐Muselli</surname></persName><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Emmanuel</forename><surname>Canet</surname></persName><affiliation><orgName type="division">Medical ICU</orgName><orgName type="institution">AP‐HP, Hôpital Saint‐Louis</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Virginie</forename><surname>Lemiale</surname></persName><affiliation><orgName type="division">Medical ICU</orgName><orgName type="institution">AP‐HP, Hôpital Saint‐Louis</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Benoît</forename><surname>Schlemmer</surname></persName><affiliation><orgName type="division">Medical ICU</orgName><orgName type="institution">AP‐HP, Hôpital Saint‐Louis</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">François</forename><surname>Simon</surname></persName><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">Elie</forename><surname>Azoulay</surname></persName><affiliation><orgName type="division">Medical ICU</orgName><orgName type="institution">AP‐HP, Hôpital Saint‐Louis</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><author xml:id="author-0007"><persName><forename type="first">Jérôme</forename><surname>Legoff</surname></persName><affiliation><orgName type="institution">Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP</orgName><address><settlement>Paris</settlement><country key="FR" xml:lang="en">FRANCE</country></address></affiliation></author><idno type="istex">D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4</idno><idno type="ark">ark:/67375/WNG-RR6CQZ98-J</idno><idno type="DOI">10.1002/jmv.23760</idno><idno type="unit">JMV23760</idno><idno type="toTypesetVersion">file:JMV.JMV23760.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="pISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><idno type="book-DOI">10.1002/(ISSN)1096-9071</idno><idno type="book-part-DOI">10.1002/jmv.v86.7</idno><idno type="product">JMV</idno><imprint><biblScope unit="vol">86</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1198">1198</biblScope><biblScope unit="page" to="1202">1202</biblScope><biblScope unit="page-count">5</biblScope><date type="published" when="2014-07"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><encodingDesc><schemaRef type="ODD" url="https://xml-schema.delivery.istex.fr/tei-istex.odd"></schemaRef><appInfo><application ident="pub2tei" version="1.0.10" when="2019-12-20"><label>pub2TEI-ISTEX</label><desc>A set of style sheets for converting XML documents encoded in various scientific publisher formats into a common TEI format.
<ref target="http://www.tei-c.org/">We use TEI</ref></desc></application></appInfo></encodingDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p>Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; <hi rend="italic">P</hi> = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. <hi rend="bold"><hi rend="italic">J. Med. Virol. 86:1198–1202, 2014</hi>.</hi> © 2013 Wiley Periodicals, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="jmv23760-kwd-0001">acute respiratory failure</term><term xml:id="jmv23760-kwd-0002">pneumonia</term><term xml:id="jmv23760-kwd-0003">polymerase chain reaction assay</term><term xml:id="jmv23760-kwd-0004">respiratory viruses</term></keywords><keywords rend="articleCategory"><term>Research Article</term></keywords><keywords rend="tocHeading1"><term>Research Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" xml:lang="en" type="serialArticle" xml:id="jmv23760"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1002/(ISSN)1096-9071</doi><issn type="print">0146-6615</issn><issn type="electronic">1096-9071</issn><idGroup><id type="product" value="JMV"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF MEDICAL VIROLOGY">Journal of Medical Virology</title><title type="short">J. Med. Virol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="70"><doi registered="yes">10.1002/jmv.v86.7</doi><copyright ownership="publisher">© 2013 Wiley Periodicals, Inc.</copyright><numberingGroup><numbering type="journalVolume" number="86">86</numbering><numbering type="journalIssue">7</numbering></numberingGroup><coverDate startDate="2014-07">July 2014</coverDate></publicationMeta><publicationMeta level="unit" position="160" type="article" status="forIssue"><doi>10.1002/jmv.23760</doi><idGroup><id type="unit" value="JMV23760"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="publisher">© 2013 Wiley Periodicals, Inc.</copyright><eventGroup><event type="manuscriptAccepted" date="2013-07-31"></event><event type="xmlCreated" agent="Thomson Digital" date="2013-09-13"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.3.1 mode:FullText" date="2014-05-02"></event><event type="publishedOnlineEarlyUnpaginated" date="2013-09-23"></event><event type="firstOnline" date="2013-09-23"></event><event type="publishedOnlineFinalForm" date="2014-05-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-07"></event></eventGroup><numberingGroup><numbering type="pageFirst">1198</numbering><numbering type="pageLast">1202</numbering></numberingGroup><correspondenceTo><lineatedText><line>Correspondence to: David Schnell, AP‐HP, Hôpital Saint‐Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France; Paris‐Diderot University, UFR de Médecine, 75010 Paris, France.</line><line>E‐mail: <email>david.schnell@sls.aphp.fr</email></line></lineatedText></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JMV.JMV23760.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Burden of respiratory viruses in patients with acute respiratory failure</title><title type="short">Respiratory Viruses Burden in ICU Patients</title><title type="shortAuthors">Schnell et al.</title></titleGroup><creators><creator xml:id="jmv23760-cr-0001" creatorRole="author" affiliationRef="#jmv23760-aff-0001 #jmv23760-aff-0002" corresponding="yes"><personName><givenNames>David</givenNames> <familyName>Schnell</familyName></personName></creator><creator xml:id="jmv23760-cr-0002" creatorRole="author" affiliationRef="#jmv23760-aff-0003"><personName><givenNames>Maud</givenNames> <familyName>Gits‐Muselli</familyName></personName></creator><creator xml:id="jmv23760-cr-0003" creatorRole="author" affiliationRef="#jmv23760-aff-0001 #jmv23760-aff-0002"><personName><givenNames>Emmanuel</givenNames> <familyName>Canet</familyName></personName></creator><creator xml:id="jmv23760-cr-0004" creatorRole="author" affiliationRef="#jmv23760-aff-0001 #jmv23760-aff-0002"><personName><givenNames>Virginie</givenNames> <familyName>Lemiale</familyName></personName></creator><creator xml:id="jmv23760-cr-0005" creatorRole="author" affiliationRef="#jmv23760-aff-0001 #jmv23760-aff-0002"><personName><givenNames>Benoît</givenNames> <familyName>Schlemmer</familyName></personName></creator><creator xml:id="jmv23760-cr-0006" creatorRole="author" affiliationRef="#jmv23760-aff-0003"><personName><givenNames>François</givenNames> <familyName>Simon</familyName></personName></creator><creator xml:id="jmv23760-cr-0007" creatorRole="author" affiliationRef="#jmv23760-aff-0001 #jmv23760-aff-0002"><personName><givenNames>Elie</givenNames> <familyName>Azoulay</familyName></personName></creator><creator xml:id="jmv23760-cr-0008" creatorRole="author" affiliationRef="#jmv23760-aff-0003"><personName><givenNames>Jérôme</givenNames> <familyName>Legoff</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="jmv23760-aff-0001" countryCode="FR"><orgDiv>Medical ICU</orgDiv><orgName>AP‐HP, Hôpital Saint‐Louis</orgName><address><city>Paris</city><country>France</country></address></affiliation><affiliation xml:id="jmv23760-aff-0002" countryCode="FR"><orgName>Paris‐Diderot University, UFR de Médecine</orgName><address><city>Paris</city><country>France</country></address></affiliation><affiliation xml:id="jmv23760-aff-0003" countryCode="FR"><orgName>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP</orgName><address><city>Paris</city><country>France</country></address></affiliation></affiliationGroup><keywordGroup type="author" xml:lang="en"><keyword xml:id="jmv23760-kwd-0001">acute respiratory failure</keyword><keyword xml:id="jmv23760-kwd-0002">pneumonia</keyword><keyword xml:id="jmv23760-kwd-0003">polymerase chain reaction assay</keyword><keyword xml:id="jmv23760-kwd-0004">respiratory viruses</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><section xml:id="jmv23760-sec-0001"><p>Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; <i>P</i> = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. <b><i>J. Med. Virol. 86:1198–1202, 2014</i>.</b> © 2013 Wiley Periodicals, Inc.</p></section></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="jmv23760-note-0005" numbered="no">All authors contributed to the study design, data collection, data analysis, and to the preparation of the manuscript.</note><note xml:id="jmv23760-note-0006" numbered="no">Conflict of interest: All authors report no conflict relevant to this study.</note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Burden of respiratory viruses in patients with acute respiratory failure</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Respiratory Viruses Burden in ICU Patients</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Burden of respiratory viruses in patients with acute respiratory failure</title></titleInfo><name type="personal"><namePart type="given">David</namePart><namePart type="family">Schnell</namePart><affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</affiliation><affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</affiliation><affiliation>Correspondence to: David Schnell, AP‐HP, Hôpital Saint‐Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France; Paris‐Diderot University, UFR de Médecine, 75010 Paris, France.E‐mail:</affiliation><affiliation>E-mail: david.schnell@sls.aphp.fr</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Maud</namePart><namePart type="family">Gits‐Muselli</namePart><affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Emmanuel</namePart><namePart type="family">Canet</namePart><affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</affiliation><affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Virginie</namePart><namePart type="family">Lemiale</namePart><affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</affiliation><affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Benoît</namePart><namePart type="family">Schlemmer</namePart><affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</affiliation><affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">François</namePart><namePart type="family">Simon</namePart><affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Elie</namePart><namePart type="family">Azoulay</namePart><affiliation>Medical ICU, AP‐HP, Hôpital Saint‐Louis, Paris, France</affiliation><affiliation>Paris‐Diderot University, UFR de Médecine, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jérôme</namePart><namePart type="family">Legoff</namePart><affiliation>Paris‐Diderot University, UFR de Médecine, Sorbone Paris Cité, Microbiology laboratory, Hôpital Saint‐Louis, APHP, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2014-07</dateIssued><dateCreated encoding="w3cdtf">2013-09-13</dateCreated><dateValid encoding="w3cdtf">2013-07-31</dateValid><copyrightDate encoding="w3cdtf">2014</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community‐acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>acute respiratory failure</topic><topic>pneumonia</topic><topic>polymerase chain reaction assay</topic><topic>respiratory viruses</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Medical Virology</title></titleInfo><titleInfo type="abbreviated"><title>J. Med. Virol.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic><topic>Research Articles</topic></subject><identifier type="ISSN">0146-6615</identifier><identifier type="eISSN">1096-9071</identifier><identifier type="DOI">10.1002/(ISSN)1096-9071</identifier><identifier type="PublisherID">JMV</identifier><part><date>2014</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><detail type="issue"><caption>no.</caption><number>7</number></detail><extent unit="pages"><start>1198</start><end>1202</end><total>5</total></extent></part></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0001"><titleInfo><title>Diagnostic strategy for acute respiratory failure in patients with haematological malignancy</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">Azoulay</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">de Miranda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Bele</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Schlemmer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Azoulay E, de Miranda S, Bele N, Schlemmer B. 2008. Diagnostic strategy for acute respiratory failure in patients with haematological malignancy. Rev Mal Respir 25:433–449.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>25</number></detail><extent unit="pages"><start>433</start><end>449</end></extent></part><relatedItem type="host"><titleInfo><title>Rev Mal Respir</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>25</number></detail><extent unit="pages"><start>433</start><end>449</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0002"><titleInfo><title>Clinical and financial benefits of rapid detection of respiratory viruses: An outcomes study</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Barenfanger</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Drake</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Leon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Mueller</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Troutt</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Barenfanger J, Drake C, Leon N, Mueller T, Troutt T. 2000. Clinical and financial benefits of rapid detection of respiratory viruses: An outcomes study. J Clin Microbiol 38:2824–2828.</note><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>38</number></detail><extent unit="pages"><start>2824</start><end>2828</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>38</number></detail><extent unit="pages"><start>2824</start><end>2828</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0003"><titleInfo><title>A virologic survey of patients admitted to a critical care unit for acute cardiorespiratory failure</title></titleInfo><name type="personal"><namePart type="given">F</namePart><namePart type="family">Carrat</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Leruez‐Ville</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tonnellier</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JL</namePart><namePart type="family">Baudel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Deshayes</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Meyer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Maury</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Galimand</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Rouzioux</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Offenstadt</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Carrat F, Leruez‐Ville M, Tonnellier M, Baudel JL, Deshayes J, Meyer P, Maury E, Galimand J, Rouzioux C, Offenstadt G. 2006. A virologic survey of patients admitted to a critical care unit for acute cardiorespiratory failure. Intensive Care Med 32:156–159.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>156</start><end>159</end></extent></part><relatedItem type="host"><titleInfo><title>Intensive Care Med</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>156</start><end>159</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0004"><titleInfo><title>Respiratory viral infections in immunocompetent and immunocompromised persons</title></titleInfo><name type="personal"><namePart type="given">RB</namePart><namePart type="family">Couch</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Englund</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Whimbey</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Couch RB, Englund JA, Whimbey E. 1997. Respiratory viral infections in immunocompetent and immunocompromised persons. Am J Med 102:2–9; discussion 25‐26.</note><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>102</number></detail><extent unit="pages"><start>2</start><end>9;</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Med</title></titleInfo><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>102</number></detail><extent unit="pages"><start>2</start><end>9;</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0005"><titleInfo><title>Epidemiology and clinical outcome of virus‐positive respiratory samples in ventilated patients: A prospective cohort study</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Daubin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Parienti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Vincent</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Vabret</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">du Cheyron</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Ramakers</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Freymuth</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Charbonneau</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Daubin C, Parienti JJ, Vincent S, Vabret A, du Cheyron D, Ramakers M, Freymuth F, Charbonneau P. 2006. Epidemiology and clinical outcome of virus‐positive respiratory samples in ventilated patients: A prospective cohort study. Crit Care 10:R142.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>R142</start></extent></part><relatedItem type="host"><titleInfo><title>Crit Care</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>R142</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0006"><titleInfo><title>Viral community‐acquired pneumonia in nonimmunocompromised adults</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">de Roux</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Marcos</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Garcia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Mensa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Ewig</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Lode</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Torres</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">de Roux A, Marcos MA, Garcia E, Mensa J, Ewig S, Lode H, Torres A. 2004. Viral community‐acquired pneumonia in nonimmunocompromised adults. Chest 125:1343–1351.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>125</number></detail><extent unit="pages"><start>1343</start><end>1351</end></extent></part><relatedItem type="host"><titleInfo><title>Chest</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>125</number></detail><extent unit="pages"><start>1343</start><end>1351</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0007"><titleInfo><title>Community‐acquired pneumonia</title></titleInfo><name type="personal"><namePart type="given">TM</namePart><namePart type="family">File</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">File TM. 2003. Community‐acquired pneumonia. Lancet 362:1991–2001.</note><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>362</number></detail><extent unit="pages"><start>1991</start><end>2001</end></extent></part><relatedItem type="host"><titleInfo><title>Lancet</title></titleInfo><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>362</number></detail><extent unit="pages"><start>1991</start><end>2001</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0008"><titleInfo><title>Frequent detection of respiratory viruses without symptoms: Toward defining clinically relevant cutoff values</title></titleInfo><name type="personal"><namePart type="given">RR</namePart><namePart type="family">Jansen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wieringa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SM</namePart><namePart type="family">Koekkoek</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CE</namePart><namePart type="family">Visser</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Pajkrt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Molenkamp</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MD</namePart><namePart type="family">de Jong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Schinkel</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jansen RR, Wieringa J, Koekkoek SM, Visser CE, Pajkrt D, Molenkamp R, de Jong MD, Schinkel J. 2011. Frequent detection of respiratory viruses without symptoms: Toward defining clinically relevant cutoff values. J Clin Microbiol 49:2631–2636.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>49</number></detail><extent unit="pages"><start>2631</start><end>2636</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>49</number></detail><extent unit="pages"><start>2631</start><end>2636</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0009"><titleInfo><title>High prevalence of respiratory viral infections in patients hospitalized in an intensive care unit for acute respiratory infections as detected by nucleic acid‐based assays</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Legoff</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Guerot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Ndjoyi‐Mbiguino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Matta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Si‐Mohamed</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Gutmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JY</namePart><namePart type="family">Fagon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Belec</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Legoff J, Guerot E, Ndjoyi‐Mbiguino A, Matta M, Si‐Mohamed A, Gutmann L, Fagon JY, Belec L. 2005. High prevalence of respiratory viral infections in patients hospitalized in an intensive care unit for acute respiratory infections as detected by nucleic acid‐based assays. J Clin Microbiol 43:455–457.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>43</number></detail><extent unit="pages"><start>455</start><end>457</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>43</number></detail><extent unit="pages"><start>455</start><end>457</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0010"><titleInfo><title>Pneumonic vs nonpneumonic acute exacerbations of COPD</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Lieberman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Gelfer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Varshavsky</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Dvoskin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Leinonen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MG</namePart><namePart type="family">Friedman</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lieberman D, Gelfer Y, Varshavsky R, Dvoskin B, Leinonen M, Friedman MG. 2002. Pneumonic vs nonpneumonic acute exacerbations of COPD. Chest 122:1264–1270.</note><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>1264</start><end>1270</end></extent></part><relatedItem type="host"><titleInfo><title>Chest</title></titleInfo><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>1264</start><end>1270</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0011"><titleInfo><title>Comparison of a multiplex reverse transcription‐PCR‐enzyme hybridization assay with conventional viral culture and immunofluorescence techniques for the detection of seven viral respiratory pathogens</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Liolios</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Jenney</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Spelman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kotsimbos</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Catton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wesselingh</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Liolios L, Jenney A, Spelman D, Kotsimbos T, Catton M, Wesselingh S. 2001. Comparison of a multiplex reverse transcription‐PCR‐enzyme hybridization assay with conventional viral culture and immunofluorescence techniques for the detection of seven viral respiratory pathogens. J Clin Microbiol 39:2779–2783.</note><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>39</number></detail><extent unit="pages"><start>2779</start><end>2783</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>39</number></detail><extent unit="pages"><start>2779</start><end>2783</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0012"><titleInfo><title>RespiFinder: A new multiparameter test to differentially identify fifteen respiratory viruses</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Reijans</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Dingemans</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CH</namePart><namePart type="family">Klaassen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JF</namePart><namePart type="family">Meis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Keijdener</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Mulders</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Eadie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">van Leeuwen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">van Belkum</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AM</namePart><namePart type="family">Horrevorts</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Simons</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Reijans M, Dingemans G, Klaassen CH, Meis JF, Keijdener J, Mulders B, Eadie K, van Leeuwen W, van Belkum A, Horrevorts AM, Simons G. 2008. RespiFinder: A new multiparameter test to differentially identify fifteen respiratory viruses. J Clin Microbiol 46:1232–1240.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>46</number></detail><extent unit="pages"><start>1232</start><end>1240</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>46</number></detail><extent unit="pages"><start>1232</start><end>1240</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0013"><titleInfo><title>Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Sethi</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sethi S. 2011. Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease. Clin Infect Dis 52:S290–S295.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>52</number></detail><extent unit="pages"><start>S290</start><end>S295</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Infect Dis</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>52</number></detail><extent unit="pages"><start>S290</start><end>S295</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0014"><titleInfo><title>Polymerase chain reaction is more sensitive than viral culture and antigen testing for the detection of respiratory viruses in adults with hematological cancer and pneumonia</title></titleInfo><name type="personal"><namePart type="given">LJ</namePart><namePart type="family">van Elden</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MG</namePart><namePart type="family">van Kraaij</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Nijhuis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KA</namePart><namePart type="family">Hendriksen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AW</namePart><namePart type="family">Dekker</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Rozenberg‐Arska</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AM</namePart><namePart type="family">van Loon</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">van Elden LJ, van Kraaij MG, Nijhuis M, Hendriksen KA, Dekker AW, Rozenberg‐Arska M, van Loon AM. 2002. Polymerase chain reaction is more sensitive than viral culture and antigen testing for the detection of respiratory viruses in adults with hematological cancer and pneumonia. Clin Infect Dis 34:177–183.</note><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>34</number></detail><extent unit="pages"><start>177</start><end>183</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Infect Dis</title></titleInfo><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>34</number></detail><extent unit="pages"><start>177</start><end>183</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="jmv23760-cit-0015"><titleInfo><title>Cost‐effectiveness of rapid diagnosis of viral respiratory tract infections in pediatric patients</title></titleInfo><name type="personal"><namePart type="given">PC</namePart><namePart type="family">Woo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SS</namePart><namePart type="family">Chiu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WH</namePart><namePart type="family">Seto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Peiris</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Woo PC, Chiu SS, Seto WH, Peiris M. 1997. Cost‐effectiveness of rapid diagnosis of viral respiratory tract infections in pediatric patients. J Clin Microbiol 35:1579–1581.</note><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>35</number></detail><extent unit="pages"><start>1579</start><end>1581</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Microbiol</title></titleInfo><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>35</number></detail><extent unit="pages"><start>1579</start><end>1581</end></extent></part></relatedItem></relatedItem><identifier type="istex">D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4</identifier><identifier type="ark">ark:/67375/WNG-RR6CQZ98-J</identifier><identifier type="DOI">10.1002/jmv.23760</identifier><identifier type="ArticleID">JMV23760</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2013 Wiley Periodicals, Inc.© 2013 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Converted from (version ) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2019-11-15</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-RR6CQZ98-J/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000409 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000409 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:D2A35B0ECD5A5DAEDE61F5A2828627489C933CD4
|texte= Burden of respiratory viruses in patients with acute respiratory failure
}}
| This area was generated with Dilib version V0.6.33. |  |