CovidV1, Istex, Corpus, bibRecord, 000179

Profiling and Searching for RNA Pseudoknot Structures in Genomes

Identifieur interne : 000179 ( Istex/Corpus ); précédent : 000178; suivant : 000180

Profiling and Searching for RNA Pseudoknot Structures in Genomes

Auteurs : Chunmei Liu ; Yinglei Song ; Russell L. Malmberg ; Liming Cai

Source :

Lecture Notes in Computer Science [ 0302-9743 ]

RBID : ISTEX:98B9F45764CD3700D5901EB6860AAAEE7C7BBD7D

Abstract

Abstract: We developed a new method that can profile and efficiently search for pseudoknot structures in noncoding RNA genes. It profiles interleaving stems in pseudoknot structures with independent Covariance Model (CM) components. The statistical alignment score for searching is obtained by combining the alignment scores from all CM components. Our experiments show that the model can achieve excellent accuracy on both random and biological data. The efficiency achieved by the method makes it possible to search for structures that contain pseudoknot in genomes of a variety of organisms.

Url:

https://api.istex.fr/ark:/67375/HCB-QWH5JJCH-Z/fulltext.pdf

DOI: 10.1007/11567752_2

Links to Exploration step

ISTEX:98B9F45764CD3700D5901EB6860AAAEE7C7BBD7D

Le document en format XML

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<Para>We developed a new method that can profile and efficiently search for pseudoknot structures in noncoding RNA genes. It profiles interleaving stems in pseudoknot structures with independent Covariance Model (CM) components. The statistical alignment score for searching is obtained by combining the alignment scores from all CM components. Our experiments show that the model can achieve excellent accuracy on both random and biological data. The efficiency achieved by the method makes it possible to search for structures that contain pseudoknot in genomes of a variety of organisms.</Para>
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Profiling and Searching for RNA Pseudoknot Structures in Genomes

Profiling and Searching for RNA Pseudoknot Structures in Genomes

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