Microfluidics‐Based Pathogen Detection: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus (Adv. Healthcare Mater. 17/2016)
Identifieur interne : 000136 ( Istex/Corpus ); précédent : 000135; suivant : 000137Microfluidics‐Based Pathogen Detection: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus (Adv. Healthcare Mater. 17/2016)
Auteurs : Il Young Jung ; Jae Bem You ; Bo Ram Choi ; Ji Su Kim ; Hyun Kyung Lee ; Bora Jang ; Han Saem Jeong ; Kyuri Lee ; Sung Gap Im ; Hyukjin LeeSource :
- Advanced Healthcare Materials [ 2192-2640 ] ; 2016-09.
Abstract
H. Lee and co‐workers demonstrate a definitive molecular diagnosis platform (DhITACT‐TR) for rapid and accurate detection of MERS coronavirus on page 2168. DhITACT‐TR offers a robust diagnosis of target RNA pathogens in pseudo‐serum specimens with minimum liquid handling as compared to conventional PCR analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.
Url:
DOI: 10.1002/adhm.201670091
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ISTEX:9397461F2B37604CA8166B61DD92E2B7F8D268CDLe document en format XML
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KGaA, Weinheim</copyright><eventGroup><event type="xmlCreated" agent="Aptara" date="2016-09-05"></event><event type="firstOnline" date="2016-09-07"></event><event type="publishedOnlineFinalForm" date="2016-09-07"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:5.0.6 mode:FullText" date="2017-02-09"></event></eventGroup><numberingGroup><numbering type="pageFirst">2146</numbering><numbering type="pageLast">2146</numbering></numberingGroup><linkGroup><link type="toTypesetVersion" href="file:ADHM.ADHM201670091.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="0"></count><count type="wordTotal" number="210"></count></countGroup><titleGroup><title type="main">Microfluidics‐Based Pathogen Detection: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus (Adv. Healthcare Mater. 17/2016)</title></titleGroup><creators><creator xml:id="adhm201670091-cr-0001" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Il Young</givenNames><familyName>Jung</familyName></personName></creator><creator xml:id="adhm201670091-cr-0002" creatorRole="author" affiliationRef="#adhm201670091-aff-0002"><personName><givenNames>Jae Bem</givenNames><familyName>You</familyName></personName></creator><creator xml:id="adhm201670091-cr-0003" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Bo Ram</givenNames><familyName>Choi</familyName></personName></creator><creator xml:id="adhm201670091-cr-0004" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Ji Su</givenNames><familyName>Kim</familyName></personName></creator><creator xml:id="adhm201670091-cr-0005" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Hyun Kyung</givenNames><familyName>Lee</familyName></personName></creator><creator xml:id="adhm201670091-cr-0006" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Bora</givenNames><familyName>Jang</familyName></personName></creator><creator xml:id="adhm201670091-cr-0007" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Han Saem</givenNames><familyName>Jeong</familyName></personName></creator><creator xml:id="adhm201670091-cr-0008" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Kyuri</givenNames><familyName>Lee</familyName></personName></creator><creator xml:id="adhm201670091-cr-0009" creatorRole="author" affiliationRef="#adhm201670091-aff-0002 #adhm201670091-aff-0003"><personName><givenNames>Sung Gap</givenNames><familyName>Im</familyName></personName></creator><creator xml:id="adhm201670091-cr-0010" creatorRole="author" affiliationRef="#adhm201670091-aff-0001"><personName><givenNames>Hyukjin</givenNames><familyName>Lee</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="adhm201670091-aff-0001" countryCode="KR"><orgDiv>College of Pharmacy</orgDiv><orgDiv>Graduate School of Pharmaceutical Sciences</orgDiv><orgName>Ewha Womans University</orgName><address><city>Seoul</city><postCode>120‐750</postCode><country>Republic of Korea</country></address></affiliation><affiliation xml:id="adhm201670091-aff-0002" countryCode="KR"><orgDiv>Department of Chemical and Biomolecular Engineering</orgDiv><orgName>Korea Advanced Institute of Science and Technology (KAIST)</orgName><address><city>Daejeon</city><postCode>34141</postCode><country>Republic of Korea</country></address></affiliation><affiliation xml:id="adhm201670091-aff-0003" countryCode="KR"><orgDiv>KAIST Institute for Nano Century</orgDiv><orgName>Korea Advanced Institute of Science and Technology (KAIST)</orgName><address><city>Daejeon</city><postCode>34141</postCode><country>Republic of Korea</country></address></affiliation></affiliationGroup><abstractGroup><abstract xml:id="adhm201670091-abs-0001" type="graphical" xml:lang="en"><p>H. Lee and co‐workers demonstrate a definitive molecular diagnosis platform (DhITACT‐TR) for rapid and accurate detection of MERS coronavirus on page 2168. DhITACT‐TR offers a robust diagnosis of target RNA pathogens in pseudo‐serum specimens with minimum liquid handling as compared to conventional PCR analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.
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Healthcare Mater. 17/2016)</title></titleInfo><name type="personal"><namePart type="given">Il Young</namePart><namePart type="family">Jung</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jae Bem</namePart><namePart type="family">You</namePart><affiliation>Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 34141, Daejeon, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bo Ram</namePart><namePart type="family">Choi</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ji Su</namePart><namePart type="family">Kim</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hyun Kyung</namePart><namePart type="family">Lee</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bora</namePart><namePart type="family">Jang</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Han Saem</namePart><namePart type="family">Jeong</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kyuri</namePart><namePart type="family">Lee</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sung Gap</namePart><namePart type="family">Im</namePart><affiliation>Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 34141, Daejeon, Republic of Korea</affiliation><affiliation>KAIST Institute for Nano Century, Korea Advanced Institute of Science and Technology (KAIST), 34141, Daejeon, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hyukjin</namePart><namePart type="family">Lee</namePart><affiliation>College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, 120‐750, Seoul, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="other" displayLabel="cover" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-7474895G-0">other</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2016-09</dateIssued><dateCreated encoding="w3cdtf">2016-09-05</dateCreated><copyrightDate encoding="w3cdtf">2016</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">1</extent><extent unit="tables">0</extent><extent unit="words">210</extent></physicalDescription><abstract type="graphical" lang="en">H. Lee and co‐workers demonstrate a definitive molecular diagnosis platform (DhITACT‐TR) for rapid and accurate detection of MERS coronavirus on page 2168. DhITACT‐TR offers a robust diagnosis of target RNA pathogens in pseudo‐serum specimens with minimum liquid handling as compared to conventional PCR analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.</abstract><relatedItem type="host"><titleInfo><title>Advanced Healthcare Materials</title></titleInfo><titleInfo type="abbreviated"><title>Adv. 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