Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation
Identifieur interne : 000115 ( Istex/Corpus ); précédent : 000114; suivant : 000116Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation
Auteurs : P. D. Griffiths ; D. Girdhar ; S. Fisher-Hoch ; M. W. Race ; R. B. HeathSource :
- Journal of Hygiene [ 0022-1724 ] ; 1984-06.
Abstract
Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (P < 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (P < 0·001) for each of the three viruses.
Url:
DOI: 10.1017/S0022172400064536
Links to Exploration step
ISTEX:6CE344E8CE5C819825AAC65744E6B55632F47E27Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title><author><name sortKey="Griffiths, P D" sort="Griffiths, P D" uniqKey="Griffiths P" first="P. D." last="Griffiths">P. D. Griffiths</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</mods:affiliation></affiliation></author><author><name sortKey="Girdhar, D" sort="Girdhar, D" uniqKey="Girdhar D" first="D." last="Girdhar">D. Girdhar</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation></author><author><name sortKey="Fisher Hoch, S" sort="Fisher Hoch, S" uniqKey="Fisher Hoch S" first="S." last="Fisher-Hoch">S. Fisher-Hoch</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</mods:affiliation></affiliation></author><author><name sortKey="Race, M W" sort="Race, M W" uniqKey="Race M" first="M. W." last="Race">M. W. Race</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</mods:affiliation></affiliation></author><author><name sortKey="Heath, R B" sort="Heath, R B" uniqKey="Heath R" first="R. B." last="Heath">R. B. Heath</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6CE344E8CE5C819825AAC65744E6B55632F47E27</idno><date when="1984" year="1984">1984</date><idno type="doi">10.1017/S0022172400064536</idno><idno type="url">https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000115</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000115</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title><author><name sortKey="Griffiths, P D" sort="Griffiths, P D" uniqKey="Griffiths P" first="P. D." last="Griffiths">P. D. Griffiths</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</mods:affiliation></affiliation></author><author><name sortKey="Girdhar, D" sort="Girdhar, D" uniqKey="Girdhar D" first="D." last="Girdhar">D. Girdhar</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation></author><author><name sortKey="Fisher Hoch, S" sort="Fisher Hoch, S" uniqKey="Fisher Hoch S" first="S." last="Fisher-Hoch">S. Fisher-Hoch</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</mods:affiliation></affiliation></author><author><name sortKey="Race, M W" sort="Race, M W" uniqKey="Race M" first="M. W." last="Race">M. W. Race</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation><affiliation><mods:affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</mods:affiliation></affiliation></author><author><name sortKey="Heath, R B" sort="Heath, R B" uniqKey="Heath R" first="R. B." last="Heath">R. B. Heath</name><affiliation><mods:affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Hygiene</title><title level="j" type="abbrev">J. Hyg.</title><idno type="ISSN">0022-1724</idno><imprint><publisher>Cambridge University Press</publisher><pubPlace>Cambridge, UK</pubPlace><date type="published" when="1984-06">1984-06</date><biblScope unit="volume">92</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="297">297</biblScope><biblScope unit="page" to="301">301</biblScope></imprint><idno type="ISSN">0022-1724</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-1724</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (P < 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (P < 0·001) for each of the three viruses.</div></front></TEI><istex><corpusName>cambridge</corpusName><author><json:item><name>P. D. Griffiths</name><affiliations><json:string>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</json:string><json:string>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</json:string></affiliations></json:item><json:item><name>D. Girdhar</name><affiliations><json:string>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</json:string></affiliations></json:item><json:item><name>S. Fisher-Hoch</name><affiliations><json:string>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</json:string><json:string>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</json:string></affiliations></json:item><json:item><name>M. W. Race</name><affiliations><json:string>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</json:string><json:string>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</json:string></affiliations></json:item><json:item><name>R. B. Heath</name><affiliations><json:string>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</json:string></affiliations></json:item></author><articleId><json:string>06453</json:string></articleId><arkIstex>ark:/67375/6GQ-6W6SFQ47-9</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>research-article</json:string></originalGenre><abstract>Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (P > 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (P > 0·001) for each of the three viruses.</abstract><qualityIndicators><score>5.521</score><pdfWordCount>2021</pdfWordCount><pdfCharCount>12201</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>5</pdfPageCount><pdfPageSize>514.8 x 752.4 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>125</abstractWordCount><abstractCharCount>835</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title><pii><json:string>S0022172400064536</json:string></pii><genre><json:string>research-article</json:string></genre><host><title>Journal of Hygiene</title><language><json:string>unknown</json:string></language><issn><json:string>0022-1724</json:string></issn><publisherId><json:string>HYG</json:string></publisherId><volume>92</volume><issue>3</issue><pages><first>297</first><last>301</last><total>5</total></pages><genre><json:string>journal</json:string></genre></host><ark><json:string>ark:/67375/6GQ-6W6SFQ47-9</json:string></ark><categories><wos></wos><scienceMetrix></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Public Health, Environmental and Occupational Health</json:string><json:string>1 - Life Sciences</json:string><json:string>2 - Immunology and Microbiology</json:string><json:string>3 - Immunology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>1984</publicationDate><copyrightDate>1984</copyrightDate><doi><json:string>10.1017/S0022172400064536</json:string></doi><id>6CE344E8CE5C819825AAC65744E6B55632F47E27</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a">Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">Cambridge University Press</publisher><pubPlace>Cambridge, UK</pubPlace><availability><licence><p>Copyright © Cambridge University Press 1984</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-G3RCRD03-V">cambridge</p></availability><date>1984</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note><note>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title><author xml:id="author-0000"><persName><forename type="first">P. D.</forename><surname>Griffiths</surname></persName><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</affiliation></author><author xml:id="author-0001"><persName><forename type="first">D.</forename><surname>Girdhar</surname></persName><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation></author><author xml:id="author-0002"><persName><forename type="first">S.</forename><surname>Fisher-Hoch</surname></persName><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</affiliation></author><author xml:id="author-0003"><persName><forename type="first">M. W.</forename><surname>Race</surname></persName><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</affiliation></author><author xml:id="author-0004"><persName><forename type="first">R. B.</forename><surname>Heath</surname></persName><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation></author><idno type="istex">6CE344E8CE5C819825AAC65744E6B55632F47E27</idno><idno type="ark">ark:/67375/6GQ-6W6SFQ47-9</idno><idno type="DOI">10.1017/S0022172400064536</idno><idno type="PII">S0022172400064536</idno><idno type="article-id">06453</idno></analytic><monogr><title level="j">Journal of Hygiene</title><title level="j" type="abbrev">J. Hyg.</title><idno type="pISSN">0022-1724</idno><idno type="publisher-id">HYG</idno><imprint><publisher>Cambridge University Press</publisher><pubPlace>Cambridge, UK</pubPlace><date type="published" when="1984-06"></date><biblScope unit="volume">92</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="297">297</biblScope><biblScope unit="page" to="301">301</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1984</date></creation><langUsage><language ident="en">en</language></langUsage><abstract style="normal"><p>Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (P < 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (P < 0·001) for each of the three viruses.</p></abstract></profileDesc><revisionDesc><change when="1984-06">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus cambridge not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="US-ASCII"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Publishing DTD v2.2 20060430//EN" URI="journalpublishing.dtd" name="istex:docType"></istex:docType><istex:document><article dtd-version="2.2" article-type="research-article"><front><journal-meta><journal-id journal-id-type="publisher-id">HYG</journal-id><journal-title>Journal of Hygiene</journal-title><abbrev-journal-title>J. Hyg.</abbrev-journal-title><issn pub-type="ppub">0022-1724</issn><publisher><publisher-name>Cambridge University Press</publisher-name><publisher-loc>Cambridge, UK</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1017/S0022172400064536</article-id><article-id pub-id-type="pii">S0022172400064536</article-id><article-id pub-id-type="publisher-id">06453</article-id><title-group><article-title>Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</article-title><alt-title alt-title-type="left-running">P. D. Griffiths and others</alt-title><alt-title alt-title-type="right-running">Inhibitors of haemagglutination</alt-title></title-group><contrib-group><contrib><name><surname>Griffiths</surname><given-names>P. D.</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="fn" rid="fn01">*</xref></contrib><contrib><name><surname>Girdhar</surname><given-names>D.</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib><name><surname>Fisher-Hoch</surname><given-names>S.</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib><name><surname>Race</surname><given-names>M. W.</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib><name><surname>Heath</surname><given-names>R. B.</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib></contrib-group><aff id="aff1"><addr-line>Virology Department</addr-line>, <addr-line>St Bartholomew's Hospital</addr-line>, <addr-line>West Smithfield</addr-line>, <addr-line>London EC1A 7BE</addr-line></aff><aff id="aff2"><label>†</label><addr-line>Special Pathogens Reference Laboratory</addr-line>, <addr-line>PHLS Centre for Applied Microbiology and Research</addr-line>, <addr-line>Porton Down</addr-line>, <addr-line>Salisbury</addr-line>, <addr-line>Wiltshire</addr-line>, <addr-line>SP4 0JG</addr-line></aff><author-notes><fn id="fn01" symbol="*" fn-type="present-address"><label>*</label><p>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</p></fn></author-notes><pub-date pub-type="ppub"><month>06</month><year>1984</year></pub-date><volume>92</volume><issue>3</issue><fpage seq="7">297</fpage><lpage>301</lpage><history><date date-type="received"><day>23</day><month>12</month><year>1983</year></date><date date-type="accepted"><day>27</day><month>01</month><year>1984</year></date></history><permissions><copyright-statement>Copyright © Cambridge University Press 1984</copyright-statement><copyright-year>1984</copyright-year><copyright-holder>Cambridge University Press</copyright-holder></permissions><abstract abstract-type="normal"><title>Summary</title><p>Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (<italic>P</italic> < 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (<italic>P</italic> < 0·001) for each of the three viruses.</p></abstract><counts><page-count count="5"></page-count></counts><custom-meta-wrap><custom-meta><meta-name>pdf</meta-name><meta-value>S0022172400064536a.pdf</meta-value></custom-meta></custom-meta-wrap></article-meta></front><back><ref-list><title>References</title><ref><citation id="ref001" citation-type="book"><name><surname>Armitage</surname><given-names>P.</given-names></name> (<year>1971</year>). <source>Statistical Methods in Medical Research</source>. <publisher-loc>Oxford</publisher-loc>: <publisher-name>Blackwell</publisher-name>.</citation></ref><ref><citation id="ref002" citation-type="journal"><name><surname>Brouwer</surname><given-names>R.</given-names></name>, <name><surname>De Groot</surname><given-names>I. G. M.</given-names></name> & <name><surname>Verheij</surname><given-names>F. B. M.</given-names></name> (<year>1974</year>). <article-title>Comparison of maternal and cord serum titres for measles and for rubella antibodies</article-title>. <source>Archiv für die gesamte Virusforschung</source> <volume>44</volume>, <fpage>237</fpage>.</citation></ref><ref><citation id="ref003" citation-type="journal"><name><surname>Clarke</surname><given-names>D. H.</given-names></name> & <name><surname>Casals</surname><given-names>J.</given-names></name> (<year>1958</year>). <article-title>Techniques for haemagglutination-inhibition with arthropodborne viruses</article-title>. <source>American Journal of Tropical Medicine and Hygiene</source> <volume>7</volume>, <fpage>561</fpage>.</citation></ref><ref><citation id="ref004" citation-type="journal"><name><surname>Doherty</surname><given-names>N.</given-names></name>, <name><surname>Ronalds</surname><given-names>C. J.</given-names></name>, <name><surname>Pattison</surname><given-names>J. R.</given-names></name> & <name><surname>Heath</surname><given-names>R. B.</given-names></name> (<year>1975</year>). <article-title>A comparative study of methods used for removing non-specific inhibitors of rubella haemagglutination from human sera</article-title>. <source>Medical Laboratory Technology</source> <volume>32</volume>, <fpage>317</fpage>.</citation></ref><ref><citation id="ref005" citation-type="journal"><name><surname>Griffiths</surname><given-names>P. D.</given-names></name>, <name><surname>Ronalds</surname><given-names>C. J.</given-names></name> & <name><surname>Heath</surname><given-names>R. B.</given-names></name> (<year>1980</year>). <article-title>A prospective study of influenza infections during pregnancy</article-title>. <source>Journal of Epidemiology and Community Health</source> <volume>34</volume>, <fpage>124</fpage>.</citation></ref><ref><citation id="ref006" citation-type="journal"><name><surname>Griffiths</surname><given-names>P. D.</given-names></name>, <name><surname>Berney</surname><given-names>S. I.</given-names></name>, <name><surname>Argent</surname><given-names>S.</given-names></name> & <name><surname>Heath</surname><given-names>R. B.</given-names></name> (<year>1982</year>). <article-title>Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation</article-title>. <source>Journal of Hygiene</source> <volume>89</volume>, <fpage>303</fpage>.</citation></ref><ref><citation id="ref007" citation-type="journal"><name><surname>Griffiths</surname><given-names>P. D.</given-names></name> & <name><surname>Baboonian</surname><given-names>C.</given-names></name> (<year>1984</year>). <article-title>A prospective study of primary cytomegalovirus infection during pregnancy (final report)</article-title>. <source>British Journal of Obstetrics and Gynaecology</source> (in press).</citation></ref><ref><citation id="ref008" citation-type="journal"><name><surname>Grint</surname><given-names>P. C. A.</given-names></name>, <name><surname>Argent</surname><given-names>S.</given-names></name> & <name><surname>Heath</surname><given-names>R. B.</given-names></name> (<year>1982</year>). <article-title>The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test</article-title>. <source>Journal of Hygiene</source> <volume>89</volume>, <fpage>329</fpage>.</citation></ref><ref><citation id="ref009" citation-type="journal"><name><surname>Kohler</surname><given-names>P. F.</given-names></name> & <name><surname>Farr</surname><given-names>R. S.</given-names></name> (<year>1966</year>). <article-title>Elevation of cord over maternal IgG immunoglobulin: evidence for an active placental IgG transport</article-title>. <source>Nature</source> <volume>210</volume>, <fpage>1070</fpage>.</citation></ref><ref><citation id="ref010" citation-type="journal"><name><surname>Longsworth</surname><given-names>L. G.</given-names></name>, <name><surname>Curtis</surname><given-names>R. M.</given-names></name> & <name><surname>Pembroke</surname><given-names>R. H.</given-names></name> (<year>1945</year>). <article-title>The electrophoretic analysis of maternal and fetal plasmas and sera</article-title>. <source>Journal of Clinical Investigation</source> <volume>24</volume>, <fpage>46</fpage>.</citation></ref><ref><citation id="ref011" citation-type="journal"><name><surname>Masurel</surname><given-names>N.</given-names></name>, <name><surname>De Bruijne</surname><given-names>J. I.</given-names></name>, <name><surname>Beuningh</surname><given-names>H. A.</given-names></name> & <name><surname>Schouten</surname><given-names>H. J. A.</given-names></name> (<year>1978</year>). <article-title>Haemagglutination-inhibition antibodies against influenza A and influenza B in maternal and neonatal sera</article-title>. <source>Journal of Hygiene</source> <volume>80</volume>, <fpage>13</fpage>.</citation></ref><ref><citation id="ref012" citation-type="journal"><name><surname>Morgan-Capner</surname><given-names>P.</given-names></name>, <name><surname>Pullen</surname><given-names>H. J. M.</given-names></name>, <name><surname>Pattison</surname><given-names>J. R.</given-names></name>, <name><surname>Bidwell</surname><given-names>D. E.</given-names></name>, <name><surname>Bartlett</surname><given-names>A.</given-names></name> & <name><surname>Voller</surname><given-names>A.</given-names></name> (<year>1979</year>). <article-title>A comparison of three tests for rubella antibody screening</article-title>. <source>Journal of Clinical Pathology</source> <volume>32</volume>, <fpage>542</fpage>.</citation></ref><ref><citation id="ref013" citation-type="journal"><name><surname>Sarateanu</surname><given-names>D. E.</given-names></name>, <name><surname>Ehrengut</surname><given-names>W.</given-names></name> & <name><surname>Fofana</surname><given-names>Y.</given-names></name> (<year>1980</year>). <article-title>Influenza and corona-virus antibodies in the newborns and their mothers in Mali</article-title>. <source>Tropenmedizin und Parasitologie</source> <volume>31</volume>, <fpage>399</fpage>.</citation></ref><ref><citation id="ref014" citation-type="journal"><name><surname>Ventura</surname><given-names>A. K.</given-names></name>, <name><surname>Ehrenkranz</surname><given-names>N. J.</given-names></name> & <name><surname>Rosenthal</surname><given-names>D.</given-names></name> (<year>1975</year>). <article-title>Placental passage of antibodies to dengue virus in persons living in a region of hyperendemic dengue virus infection</article-title>. <source>Journal of Infectious Diseases</source> <volume>131</volume>, S <fpage>62</fpage>.</citation></ref></ref-list></back></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation</title></titleInfo><name type="personal"><namePart type="given">P. D.</namePart><namePart type="family">Griffiths</namePart><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Girdhar</namePart><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Fisher-Hoch</namePart><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M. W.</namePart><namePart type="family">Race</namePart><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><affiliation>Special Pathogens Reference Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, SP4 0JG</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R. B.</namePart><namePart type="family">Heath</namePart><affiliation>Virology Department, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Cambridge University Press</publisher><place><placeTerm type="text">Cambridge, UK</placeTerm></place><dateIssued encoding="w3cdtf">1984-06</dateIssued><copyrightDate encoding="w3cdtf">1984</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract type="normal">Pregnancies were identified in which maternal IgG antibodies against rubella virus were not detectable by single radial haemolysis. Twenty paired maternal/cord sera were then tested for haemagglutination-inhibiting (HI) activity against rubella virus without kaolin pretreatment of the sera. In the absence of specific antibody, the HI activity observed could thus be ascribed to the effect of non-specific inhibitors. The HI activity in maternal sera was significantly (P < 0·001) higher than that in cord sera. The 20 pairs of sera were similarly tested against a bunyavirus, an alphavirus and a flavivirus, both with and without kaolin pretreatment. The results showed non-specific inhibitors were found to higher titre in maternal sera, with the difference being statistically significant (P < 0·001) for each of the three viruses.</abstract><note type="footnotes">Present address: Virus Laboratory, Royal Free Hospital Medical School, London, NW3.</note><relatedItem type="host"><titleInfo><title>Journal of Hygiene</title></titleInfo><titleInfo type="abbreviated"><title>J. Hyg.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0022-1724</identifier><identifier type="PublisherID">HYG</identifier><part><date>1984</date><detail type="volume"><caption>vol.</caption><number>92</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>297</start><end>301</end><total>5</total></extent></part></relatedItem><identifier type="istex">6CE344E8CE5C819825AAC65744E6B55632F47E27</identifier><identifier type="ark">ark:/67375/6GQ-6W6SFQ47-9</identifier><identifier type="DOI">10.1017/S0022172400064536</identifier><identifier type="PII">S0022172400064536</identifier><identifier type="ArticleID">06453</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © Cambridge University Press 1984</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-G3RCRD03-V">cambridge</recordContentSource><recordOrigin>Copyright © Cambridge University Press 1984</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6GQ-6W6SFQ47-9/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000115 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000115 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:6CE344E8CE5C819825AAC65744E6B55632F47E27
|texte= Antibody against viruses in maternal and cord sera: non-specific inhibitors are found to higher titre on the maternal side of the circulation
}}
| This area was generated with Dilib version V0.6.33. |  |