Serological Studies on the Potential Synergism of Porcine Reproductive and Respiratory Syndrome Virus and Influenza‐, Corona‐ and Paramyxoviruses in the Induction of Respiratory Symptoms in Swine
Identifieur interne : 000084 ( Istex/Corpus ); précédent : 000083; suivant : 000085Serological Studies on the Potential Synergism of Porcine Reproductive and Respiratory Syndrome Virus and Influenza‐, Corona‐ and Paramyxoviruses in the Induction of Respiratory Symptoms in Swine
Auteurs : M. H. Groschup ; A. Brun ; B. HaasSource :
- Journal of Veterinary Medicine, Series B [ 0931-1793 ] ; 1993-01-12.
Abstract
Sera from 265 finishing pigs belonging to 70 herds, in which severe respiratory disorders were observed, were examined for antibody prevalence to porcine reproductive and respiratory syndrome virus (PRRSV), influenza virus subtypes H3N2 and H1N1, porcine respiratory corona virus (PRCV) and a recently described porcine paramyxovirus (PPMV). By immuneperoxidase‐monolayer assay 69.1 % of these sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 55.1 % of the sera for influenza virus subtype H1N1 (strain A/swine/Arnsberg/1/81). in 51.3 % for influenza virus subtype H3N2 (strain A/Hong Kong/1/68) and in 14.3 % for PPMV. PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera. In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. Depletion of lung macrophages after PRRSV infection is discussed as a possible mechanism for the promotion of secondary infections.
Url:
DOI: 10.1111/j.1439-0450.1993.tb00192.x
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Box 1149, 72001 Tübingen, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Veterinary Medicine, Series B</title><title level="j" type="alt">JOURNAL OF VETERINARY MEDICINE SERIES B</title><idno type="ISSN">0931-1793</idno><idno type="eISSN">1439-0450</idno><imprint><biblScope unit="vol">40</biblScope><biblScope unit="issue">1‐10</biblScope><biblScope unit="page" from="681">681</biblScope><biblScope unit="page" to="689">689</biblScope><biblScope unit="page-count">9</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1993-01-12">1993-01-12</date></imprint><idno type="ISSN">0931-1793</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0931-1793</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sera from 265 finishing pigs belonging to 70 herds, in which severe respiratory disorders were observed, were examined for antibody prevalence to porcine reproductive and respiratory syndrome virus (PRRSV), influenza virus subtypes H3N2 and H1N1, porcine respiratory corona virus (PRCV) and a recently described porcine paramyxovirus (PPMV). By immuneperoxidase‐monolayer assay 69.1 % of these sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 55.1 % of the sera for influenza virus subtype H1N1 (strain A/swine/Arnsberg/1/81). in 51.3 % for influenza virus subtype H3N2 (strain A/Hong Kong/1/68) and in 14.3 % for PPMV. PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera. In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. 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By immuneperoxidase‐monolayer assay 69.1 % of these sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 55.1 % of the sera for influenza virus subtype H1N1 (strain A/swine/Arnsberg/1/81). in 51.3 % for influenza virus subtype H3N2 (strain A/Hong Kong/1/68) and in 14.3 % for PPMV. PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera. In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. 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PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera.</p><p>In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. Depletion of lung macrophages after PRRSV infection is discussed as a possible mechanism for the promotion of secondary infections.</p></abstract><textClass><keywords rend="tocHeading1"><term>Original Papers/Originalarbeiten</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-PDNMBGS6-T/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1439-0450</doi><issn type="print">0931-1793</issn><issn type="electronic">1439-0450</issn><idGroup><id type="product" value="ZPH"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF VETERINARY MEDICINE SERIES B">Journal of Veterinary Medicine, Series B</title></titleGroup></publicationMeta><publicationMeta level="part" position="01001"><doi origin="wiley">10.1111/zph.1993.40.issue-1-10</doi><numberingGroup><numbering type="journalVolume" number="40">40</numbering><numbering type="journalIssue">1‐10</numbering></numberingGroup><coverDate startDate="1993-01-12">January‐December 1993</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="91" status="forIssue"><doi origin="wiley">10.1111/j.1439-0450.1993.tb00192.x</doi><idGroup><id type="unit" value="ZPH192"></id></idGroup><countGroup><count type="pageTotal" number="9"></count></countGroup><titleGroup><title type="tocHeading1">Original Papers/Originalarbeiten</title></titleGroup><copyright>© 1993 Blackwell Verlag GmbH</copyright><eventGroup><event type="firstOnline" date="2010-05-13"></event><event type="publishedOnlineFinalForm" date="2010-05-13"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.6 mode:FullText source:HeaderRef result:HeaderRef" date="2010-05-17"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-11"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="681">681</numbering><numbering type="pageLast" number="689">689</numbering></numberingGroup><correspondenceTo><lineatedText><line>Federal Research Centre for Virus Diseases of Animals, Tübingen</line><line>Laboratoire IFFA, Rhone Merieux, Lyon</line><line>Federal Research Centre for Virus Diseases of Animals, P.O. Box 1149, 72001 Tübingen, Germany</line></lineatedText></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ZPH.ZPH192.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received for publication October 28, 1993</unparsedEditorialHistory><countGroup><count type="referenceTotal" number="21"></count><count type="linksCrossRef" number="7"></count></countGroup><titleGroup><title type="main">Serological Studies on the Potential Synergism of Porcine Reproductive and Respiratory Syndrome Virus and Influenza‐, Corona‐ and Paramyxoviruses in the Induction of Respiratory Symptoms in Swine</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1" corresponding="yes"><personName><givenNames>M. H.</givenNames><familyName>Groschup</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1" corresponding="yes"><personName><givenNames>A.</givenNames><familyName>Brun</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1" corresponding="yes"><personName><givenNames>B.</givenNames><familyName>Haas</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Federal Research Centre for Virus Diseases of Animals, Tübingen Laboratoire IFFA, Rhone Merieux, Lyon</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Summary</title><p>Sera from 265 finishing pigs belonging to 70 herds, in which severe respiratory disorders were observed, were examined for antibody prevalence to porcine reproductive and respiratory syndrome virus (PRRSV), influenza virus subtypes H3N2 and H1N1, porcine respiratory corona virus (PRCV) and a recently described porcine paramyxovirus (PPMV). By immuneperoxidase‐monolayer assay 69.1 % of these sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 55.1 % of the sera for influenza virus subtype H1N1 (strain A/swine/Arnsberg/1/81). in 51.3 % for influenza virus subtype H3N2 (strain A/Hong Kong/1/68) and in 14.3 % for PPMV. PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera.</p><p>In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. Depletion of lung macrophages after PRRSV infection is discussed as a possible mechanism for the promotion of secondary infections.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Serological Studies on the Potential Synergism of Porcine Reproductive and Respiratory Syndrome Virus and Influenza‐, Corona‐ and Paramyxoviruses in the Induction of Respiratory Symptoms in Swine</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Serological Studies on the Potential Synergism of Porcine Reproductive and Respiratory Syndrome Virus and Influenza‐, Corona‐ and Paramyxoviruses in the Induction of Respiratory Symptoms in Swine</title></titleInfo><name type="personal"><namePart type="given">M. H.</namePart><namePart type="family">Groschup</namePart><affiliation>Federal Research Centre for Virus Diseases of Animals, Tübingen Laboratoire IFFA, Rhone Merieux, Lyon</affiliation><affiliation>Federal Research Centre for Virus Diseases of Animals, TübingenLaboratoire IFFA, Rhone Merieux, LyonFederal Research Centre for Virus Diseases of Animals, P.O. Box 1149, 72001 Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Brun</namePart><affiliation>Federal Research Centre for Virus Diseases of Animals, Tübingen Laboratoire IFFA, Rhone Merieux, Lyon</affiliation><affiliation>Federal Research Centre for Virus Diseases of Animals, TübingenLaboratoire IFFA, Rhone Merieux, LyonFederal Research Centre for Virus Diseases of Animals, P.O. Box 1149, 72001 Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.</namePart><namePart type="family">Haas</namePart><affiliation>Federal Research Centre for Virus Diseases of Animals, Tübingen Laboratoire IFFA, Rhone Merieux, Lyon</affiliation><affiliation>Federal Research Centre for Virus Diseases of Animals, TübingenLaboratoire IFFA, Rhone Merieux, LyonFederal Research Centre for Virus Diseases of Animals, P.O. Box 1149, 72001 Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1993-01-12</dateIssued><edition>Received for publication October 28, 1993</edition><copyrightDate encoding="w3cdtf">1993</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="references">21</extent><extent unit="linksCrossRef">7</extent></physicalDescription><abstract lang="en">Sera from 265 finishing pigs belonging to 70 herds, in which severe respiratory disorders were observed, were examined for antibody prevalence to porcine reproductive and respiratory syndrome virus (PRRSV), influenza virus subtypes H3N2 and H1N1, porcine respiratory corona virus (PRCV) and a recently described porcine paramyxovirus (PPMV). By immuneperoxidase‐monolayer assay 69.1 % of these sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 55.1 % of the sera for influenza virus subtype H1N1 (strain A/swine/Arnsberg/1/81). in 51.3 % for influenza virus subtype H3N2 (strain A/Hong Kong/1/68) and in 14.3 % for PPMV. PRCV specific antibodies, as determined by differential competitive blocking enzyme‐linked immunosorbant assay were demonstrated in 192 of 236 (81.3 %) sera. In order to reveal associations interspecific coefficients were calculated for antibody prevalence between PRRSV and the other viruses. Positive associations to PRRSV titres were found to PRCV, PPMV and influenza virus subtype H1N1 titres. χ‐square analysis showed the statistical significance of associations regarding PRCV and influenza virus subtype H1N1. 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