Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.
Identifieur interne : 000969 ( Main/Exploration ); précédent : 000968; suivant : 000970Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.
Auteurs : Gerasimos N. Konstantinou [Canada] ; Jonathan Downar [Canada] ; Zafiris J. Daskalakis [Canada] ; Daniel M. Blumberger [Canada]Source :
- The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [ 1545-7214 ] ; 2020.
Descripteurs français
- KwdFr :
- Accessibilité des services de santé (MeSH), Betacoronavirus (MeSH), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (épidémiologie), Pandémies (MeSH), Pneumopathie virale (épidémiologie), Questionnaire de santé du patient (MeSH), Résultat thérapeutique (MeSH), Stimulation magnétique transcrânienne (méthodes), Sujet âgé (MeSH), Trouble dépressif majeur (psychologie), Trouble dépressif majeur (thérapie), Trouble dépressif résistant aux traitements (psychologie), Trouble dépressif résistant aux traitements (thérapie), Électroconvulsivothérapie (MeSH).
- MESH :
- méthodes : Stimulation magnétique transcrânienne.
- psychologie : Trouble dépressif majeur, Trouble dépressif résistant aux traitements.
- thérapie : Trouble dépressif majeur, Trouble dépressif résistant aux traitements.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Accessibilité des services de santé, Betacoronavirus, Femelle, Humains, Pandémies, Questionnaire de santé du patient, Résultat thérapeutique, Sujet âgé, Électroconvulsivothérapie.
English descriptors
- KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (epidemiology), Depressive Disorder, Major (psychology), Depressive Disorder, Major (therapy), Depressive Disorder, Treatment-Resistant (psychology), Depressive Disorder, Treatment-Resistant (therapy), Electroconvulsive Therapy (MeSH), Female (MeSH), Health Services Accessibility (MeSH), Humans (MeSH), Pandemics (MeSH), Patient Health Questionnaire (MeSH), Pneumonia, Viral (epidemiology), Transcranial Magnetic Stimulation (methods), Treatment Outcome (MeSH).
- MESH :
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- methods : Transcranial Magnetic Stimulation.
- psychology : Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant.
- therapy : Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant.
- Aged, Betacoronavirus, Electroconvulsive Therapy, Female, Health Services Accessibility, Humans, Pandemics, Patient Health Questionnaire, Treatment Outcome.
Abstract
OBJECTIVE
Electroconvulsive therapy (ECT) is an essential psychiatric service with an important role in treating older adults with severe or treatment-resistant depression. During the COVID-19 pandemic, ECT services have be constrained by infection control measures. We report a case of a 66-year-old female patient with a severe major depressive episode who had previously responded to right unilateral ECT and was treated with two modified accelerated intermittent theta-burst stimulation (aiTBS) protocols.
METHODS
The two aiTBS courses consisted of eight daily sessions over five consecutive days, followed by gradual tapering, using 1,800 pulses per session pre-COVID-19 (first course), and 600 pulses per session during the pandemic (second course).
RESULTS
Moderate to severe baseline depressive symptoms reached remission levels after both courses.
CONCLUSION
The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.
DOI: 10.1016/j.jagp.2020.07.007
PubMed: 32753340
PubMed Central: PMC7362844
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<term>Depressive Disorder, Major (therapy)</term>
<term>Depressive Disorder, Treatment-Resistant (psychology)</term>
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<term>Trouble dépressif résistant aux traitements (psychologie)</term>
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<term>Trouble dépressif résistant aux traitements</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>Electroconvulsive therapy (ECT) is an essential psychiatric service with an important role in treating older adults with severe or treatment-resistant depression. During the COVID-19 pandemic, ECT services have be constrained by infection control measures. We report a case of a 66-year-old female patient with a severe major depressive episode who had previously responded to right unilateral ECT and was treated with two modified accelerated intermittent theta-burst stimulation (aiTBS) protocols.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>The two aiTBS courses consisted of eight daily sessions over five consecutive days, followed by gradual tapering, using 1,800 pulses per session pre-COVID-19 (first course), and 600 pulses per session during the pandemic (second course).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Moderate to severe baseline depressive symptoms reached remission levels after both courses.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.</p>
</div>
</front>
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