CovidSeniorV1, Main, Curation, bibRecord, 000353

Clinical features and outcomes of seven patients with COVID-19 in a family cluster.

Identifieur interne : 000353 ( Main/Curation ); précédent : 000352; suivant : 000354

Clinical features and outcomes of seven patients with COVID-19 in a family cluster.

Auteurs : Yiling Zhang [République populaire de Chine] ; Cheng Zhang [République populaire de Chine] ; Ying Hu [République populaire de Chine] ; Hongmei Yao [République populaire de Chine] ; Xianchun Zeng [République populaire de Chine] ; Changrong Hu [République populaire de Chine] ; Li Zhao [République populaire de Chine] ; Xiangyan Zhang [République populaire de Chine] ; Xianwei Ye [République populaire de Chine]

Source :

BMC infectious diseases [ 1471-2334 ] ; 2020.

RBID : pubmed:32883217

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Betacoronavirus (isolement et purification), Betacoronavirus (pathogénicité), Chine (épidémiologie), Enfant (MeSH), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (physiopathologie), Infections à coronavirus (transmission), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (physiopathologie), Pneumopathie virale (transmission), Pneumopathie virale (virologie), Pneumopathie virale (épidémiologie), Santé de la famille (MeSH), Sujet âgé (MeSH), Études rétrospectives (MeSH).
MESH :
- isolement et purification : Betacoronavirus.
- pathogénicité : Betacoronavirus.
- physiopathologie : Infections à coronavirus, Pneumopathie virale.
- virologie : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Chine, Infections à coronavirus, Pneumopathie virale.
- Adolescent, Adulte, Enfant, Femelle, Humains, Mâle, Pandémies, Santé de la famille, Sujet âgé, Études rétrospectives.
Wicri :
- geographic : République populaire de Chine.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Betacoronavirus (isolation & purification), Betacoronavirus (pathogenicity), Child (MeSH), China (epidemiology), Coronavirus Infections (epidemiology), Coronavirus Infections (physiopathology), Coronavirus Infections (transmission), Coronavirus Infections (virology), Family Health (MeSH), Female (MeSH), Humans (MeSH), Male (MeSH), Pandemics (MeSH), Pneumonia, Viral (epidemiology), Pneumonia, Viral (physiopathology), Pneumonia, Viral (transmission), Pneumonia, Viral (virology), Retrospective Studies (MeSH).
MESH :
- geographic , epidemiology : China.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- isolation & purification : Betacoronavirus.
- pathogenicity : Betacoronavirus.
- physiopathology : Coronavirus Infections, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adolescent, Adult, Aged, Child, Family Health, Female, Humans, Male, Pandemics, Retrospective Studies.

Abstract

BACKGROUND

The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19).

CASE PRESENTATION

We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.

CONCLUSIONS

In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.

DOI: 10.1186/s12879-020-05364-1
PubMed: 32883217
PubMed Central: PMC7468093

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<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>Child (MeSH)</term>
<term>China (epidemiology)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (physiopathology)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Coronavirus Infections (virology)</term>
<term>Family Health (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (physiopathology)</term>
<term>Pneumonia, Viral (transmission)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Retrospective Studies (MeSH)</term>
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<term>Adulte (MeSH)</term>
<term>Betacoronavirus (isolement et purification)</term>
<term>Betacoronavirus (pathogénicité)</term>
<term>Chine (épidémiologie)</term>
<term>Enfant (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (physiopathologie)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
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<term>Pandémies (MeSH)</term>
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<term>Pneumopathie virale (transmission)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Pneumopathie virale (épidémiologie)</term>
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<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
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<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Betacoronavirus</term>
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<term>Adulte</term>
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<term>Humains</term>
<term>Mâle</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CASE PRESENTATION</b>
</p>
<p>We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.</p>
</div>
</front>
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<Day>08</Day>
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<ArticleTitle>Clinical features and outcomes of seven patients with COVID-19 in a family cluster.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19).</AbstractText>
<AbstractText Label="CASE PRESENTATION" NlmCategory="METHODS">We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Yiling</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, State Key Laboratory of Diagnosis and Treatment of Lung Immune Diseases, Guiyang, 550002, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Cheng</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, State Key Laboratory of Diagnosis and Treatment of Lung Immune Diseases, Guiyang, 550002, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hu</LastName>
<ForeName>Ying</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, State Key Laboratory of Diagnosis and Treatment of Lung Immune Diseases, Guiyang, 550002, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yao</LastName>
<ForeName>Hongmei</ForeName>
<Initials>H</Initials>
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<ArticleIdList><ArticleId IdType="pubmed">32883217</ArticleId>
<ArticleId IdType="doi">10.1186/s12879-020-05364-1</ArticleId>
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</ArticleIdList>
<ReferenceList><Reference><Citation>N Engl J Med. 2020 Feb 20;382(8):727-733</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31978945</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>AJR Am J Roentgenol. 2020 Aug;215(2):338-343</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32181672</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Cell Mol Biol. 2013 Jun;48(6):742-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23418343</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2020 May 11;221(11):1770-1774</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32179910</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Mar 16;:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32173725</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2020 Jun;92(6):568-576</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32134116</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Feb 22;395(10224):565-574</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32007145</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):769-777</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32176772</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Mar 28;395(10229):1054-1062</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32171076</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Microbiol. 2019 Mar;17(3):181-192</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30531947</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Feb 15;395(10223):497-506</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31986264</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
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	Serveur d'exploration sur la COVID chez les séniors
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Clinical features and outcomes of seven patients with COVID-19 in a family cluster.

Clinical features and outcomes of seven patients with COVID-19 in a family cluster.

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