COVID-19 in rheumatic diseases in Italy: first results from the Italian registry of the Italian Society for Rheumatology (CONTROL-19).
Identifieur interne : 000957 ( Main/Corpus ); précédent : 000956; suivant : 000958COVID-19 in rheumatic diseases in Italy: first results from the Italian registry of the Italian Society for Rheumatology (CONTROL-19).
Auteurs : Carlo Alberto Scirè ; Greta Carrara ; Anna Zanetti ; Gianpiero Landolfi ; Cecilia Chighizola ; Alessia Alunno ; Laura Andreoli ; Roberto Caporali ; Roberto Gerli ; Gian Domenico Sebastiani ; Guido Valesini ; Luigi SinigagliaSource :
- Clinical and experimental rheumatology [ 0392-856X ]
English descriptors
- KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (complications), Epidemiological Monitoring (MeSH), Female (MeSH), Humans (MeSH), Italy (epidemiology), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (complications), Registries (MeSH), Retrospective Studies (MeSH), Rheumatic Diseases (complications), Rheumatic Diseases (virology), Rheumatology (MeSH).
- MESH :
- geographic , epidemiology : Italy.
- complications : Coronavirus Infections, Pneumonia, Viral, Rheumatic Diseases.
- virology : Rheumatic Diseases.
- Aged, Betacoronavirus, Epidemiological Monitoring, Female, Humans, Male, Middle Aged, Pandemics, Registries, Retrospective Studies, Rheumatology.
Abstract
OBJECTIVES
Italy was one of the first countries significantly affected by the coronavirus disease 2019 (COVID-19) epidemic. The Italian Society for Rheumatology promptly launched a retrospective and anonymised data collection to monitor COVID-19 in patients with rheumatic and musculoskeletal diseases (RMDs), the CONTROL-19 surveillance database, which is part of the COVID-19 Global Rheumatology Alliance.
METHODS
CONTROL-19 includes patients with RMDs and proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) updated until May 3rd 2020. In this analysis, only molecular diagnoses were included. The data collection covered demographic data, medical history (general and RMD-related), treatments and COVID-19 related features, treatments, and outcome. In this paper, we report the first descriptive data from the CONTROL-19 registry.
RESULTS
The population of the first 232 patients (36% males) consisted mainly of elderly patients (mean age 62.2 years), who used corticosteroids (51.7%), and suffered from multi-morbidity (median comorbidities 2). Rheumatoid arthritis was the most frequent disease (34.1%), followed by spondyloarthritis (26.3%), connective tissue disease (21.1%) and vasculitis (11.2%). Most cases had an active disease (69.4%). Clinical presentation of COVID-19 was typical, with systemic symptoms (fever and asthenia) and respiratory symptoms. The overall outcome was severe, with high frequencies of hospitalisation (69.8%), respiratory support oxygen (55.7%), non-invasive ventilation (20.9%) or mechanical ventilation (7.5%), and 19% of deaths. Male patients typically manifested a worse prognosis. Immunomodulatory treatments were not significantly associated with an increased risk of intensive care unit admission/mechanical ventilation/death.
CONCLUSIONS
Although the report mainly includes the most severe cases, its temporal and spatial trend supports the validity of the national surveillance system. More complete data are being acquired in order to both test the hypothesis that RMD patients may have a different outcome from that of the general population and determine the safety of immunomodulatory treatments.
PubMed: 32723435
Links to Exploration step
pubmed:32723435Le document en format XML
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<author><name sortKey="Scire, Carlo Alberto" sort="Scire, Carlo Alberto" uniqKey="Scire C" first="Carlo Alberto" last="Scirè">Carlo Alberto Scirè</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, and Rheumatology Unit, Department of Medical Sciences, University of Ferrara, Italy.</nlm:affiliation>
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<author><name sortKey="Carrara, Greta" sort="Carrara, Greta" uniqKey="Carrara G" first="Greta" last="Carrara">Greta Carrara</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy.</nlm:affiliation>
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<author><name sortKey="Zanetti, Anna" sort="Zanetti, Anna" uniqKey="Zanetti A" first="Anna" last="Zanetti">Anna Zanetti</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, and Department of Statistics and Quantitative Methods, Division of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Milan, Italy.</nlm:affiliation>
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<author><name sortKey="Landolfi, Gianpiero" sort="Landolfi, Gianpiero" uniqKey="Landolfi G" first="Gianpiero" last="Landolfi">Gianpiero Landolfi</name>
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<author><name sortKey="Chighizola, Cecilia" sort="Chighizola, Cecilia" uniqKey="Chighizola C" first="Cecilia" last="Chighizola">Cecilia Chighizola</name>
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<author><name sortKey="Alunno, Alessia" sort="Alunno, Alessia" uniqKey="Alunno A" first="Alessia" last="Alunno">Alessia Alunno</name>
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<author><name sortKey="Andreoli, Laura" sort="Andreoli, Laura" uniqKey="Andreoli L" first="Laura" last="Andreoli">Laura Andreoli</name>
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<author><name sortKey="Caporali, Roberto" sort="Caporali, Roberto" uniqKey="Caporali R" first="Roberto" last="Caporali">Roberto Caporali</name>
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<author><name sortKey="Gerli, Roberto" sort="Gerli, Roberto" uniqKey="Gerli R" first="Roberto" last="Gerli">Roberto Gerli</name>
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<author><name sortKey="Sebastiani, Gian Domenico" sort="Sebastiani, Gian Domenico" uniqKey="Sebastiani G" first="Gian Domenico" last="Sebastiani">Gian Domenico Sebastiani</name>
<affiliation><nlm:affiliation>Rheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Valesini, Guido" sort="Valesini, Guido" uniqKey="Valesini G" first="Guido" last="Valesini">Guido Valesini</name>
<affiliation><nlm:affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Sinigaglia, Luigi" sort="Sinigaglia, Luigi" uniqKey="Sinigaglia L" first="Luigi" last="Sinigaglia">Luigi Sinigaglia</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">COVID-19 in rheumatic diseases in Italy: first results from the Italian registry of the Italian Society for Rheumatology (CONTROL-19).</title>
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</affiliation>
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<author><name sortKey="Carrara, Greta" sort="Carrara, Greta" uniqKey="Carrara G" first="Greta" last="Carrara">Greta Carrara</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Zanetti, Anna" sort="Zanetti, Anna" uniqKey="Zanetti A" first="Anna" last="Zanetti">Anna Zanetti</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, and Department of Statistics and Quantitative Methods, Division of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Landolfi, Gianpiero" sort="Landolfi, Gianpiero" uniqKey="Landolfi G" first="Gianpiero" last="Landolfi">Gianpiero Landolfi</name>
<affiliation><nlm:affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chighizola, Cecilia" sort="Chighizola, Cecilia" uniqKey="Chighizola C" first="Cecilia" last="Chighizola">Cecilia Chighizola</name>
<affiliation><nlm:affiliation>Experimental Laboratory of Immunological and Rheumatologic Researches, Immunology and Rheumatology Unit, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Alunno, Alessia" sort="Alunno, Alessia" uniqKey="Alunno A" first="Alessia" last="Alunno">Alessia Alunno</name>
<affiliation><nlm:affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Andreoli, Laura" sort="Andreoli, Laura" uniqKey="Andreoli L" first="Laura" last="Andreoli">Laura Andreoli</name>
<affiliation><nlm:affiliation>Rheumatology and Clinical Immunology Unit, ASST Spedali Civili; Department of Clinical and Experimental Sciences, University of Brescia, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Caporali, Roberto" sort="Caporali, Roberto" uniqKey="Caporali R" first="Roberto" last="Caporali">Roberto Caporali</name>
<affiliation><nlm:affiliation>Department of Clinical Sciences and Community Health, University of Milan, ASST Pini CTO, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gerli, Roberto" sort="Gerli, Roberto" uniqKey="Gerli R" first="Roberto" last="Gerli">Roberto Gerli</name>
<affiliation><nlm:affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sebastiani, Gian Domenico" sort="Sebastiani, Gian Domenico" uniqKey="Sebastiani G" first="Gian Domenico" last="Sebastiani">Gian Domenico Sebastiani</name>
<affiliation><nlm:affiliation>Rheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Valesini, Guido" sort="Valesini, Guido" uniqKey="Valesini G" first="Guido" last="Valesini">Guido Valesini</name>
<affiliation><nlm:affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sinigaglia, Luigi" sort="Sinigaglia, Luigi" uniqKey="Sinigaglia L" first="Luigi" last="Sinigaglia">Luigi Sinigaglia</name>
<affiliation><nlm:affiliation>Italian Society for Rheumatology, Milan, Italy.</nlm:affiliation>
</affiliation>
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<term>Betacoronavirus (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Epidemiological Monitoring (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Italy (epidemiology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Registries (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Rheumatic Diseases (complications)</term>
<term>Rheumatic Diseases (virology)</term>
<term>Rheumatology (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Italy</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Rheumatic Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Rheumatic Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Betacoronavirus</term>
<term>Epidemiological Monitoring</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Registries</term>
<term>Retrospective Studies</term>
<term>Rheumatology</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b>
</p>
<p>Italy was one of the first countries significantly affected by the coronavirus disease 2019 (COVID-19) epidemic. The Italian Society for Rheumatology promptly launched a retrospective and anonymised data collection to monitor COVID-19 in patients with rheumatic and musculoskeletal diseases (RMDs), the CONTROL-19 surveillance database, which is part of the COVID-19 Global Rheumatology Alliance.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>CONTROL-19 includes patients with RMDs and proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) updated until May 3rd 2020. In this analysis, only molecular diagnoses were included. The data collection covered demographic data, medical history (general and RMD-related), treatments and COVID-19 related features, treatments, and outcome. In this paper, we report the first descriptive data from the CONTROL-19 registry.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>The population of the first 232 patients (36% males) consisted mainly of elderly patients (mean age 62.2 years), who used corticosteroids (51.7%), and suffered from multi-morbidity (median comorbidities 2). Rheumatoid arthritis was the most frequent disease (34.1%), followed by spondyloarthritis (26.3%), connective tissue disease (21.1%) and vasculitis (11.2%). Most cases had an active disease (69.4%). Clinical presentation of COVID-19 was typical, with systemic symptoms (fever and asthenia) and respiratory symptoms. The overall outcome was severe, with high frequencies of hospitalisation (69.8%), respiratory support oxygen (55.7%), non-invasive ventilation (20.9%) or mechanical ventilation (7.5%), and 19% of deaths. Male patients typically manifested a worse prognosis. Immunomodulatory treatments were not significantly associated with an increased risk of intensive care unit admission/mechanical ventilation/death.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Although the report mainly includes the most severe cases, its temporal and spatial trend supports the validity of the national surveillance system. More complete data are being acquired in order to both test the hypothesis that RMD patients may have a different outcome from that of the general population and determine the safety of immunomodulatory treatments.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32723435</PMID>
<DateCompleted><Year>2020</Year>
<Month>07</Month>
<Day>31</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>08</Month>
<Day>03</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0392-856X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>38</Volume>
<Issue>4</Issue>
<PubDate><MedlineDate>2020 Jul-Aug</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Clinical and experimental rheumatology</Title>
<ISOAbbreviation>Clin Exp Rheumatol</ISOAbbreviation>
</Journal>
<ArticleTitle>COVID-19 in rheumatic diseases in Italy: first results from the Italian registry of the Italian Society for Rheumatology (CONTROL-19).</ArticleTitle>
<Pagination><MedlinePgn>748-753</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVES">Italy was one of the first countries significantly affected by the coronavirus disease 2019 (COVID-19) epidemic. The Italian Society for Rheumatology promptly launched a retrospective and anonymised data collection to monitor COVID-19 in patients with rheumatic and musculoskeletal diseases (RMDs), the CONTROL-19 surveillance database, which is part of the COVID-19 Global Rheumatology Alliance.</AbstractText>
<AbstractText Label="METHODS">CONTROL-19 includes patients with RMDs and proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) updated until May 3rd 2020. In this analysis, only molecular diagnoses were included. The data collection covered demographic data, medical history (general and RMD-related), treatments and COVID-19 related features, treatments, and outcome. In this paper, we report the first descriptive data from the CONTROL-19 registry.</AbstractText>
<AbstractText Label="RESULTS">The population of the first 232 patients (36% males) consisted mainly of elderly patients (mean age 62.2 years), who used corticosteroids (51.7%), and suffered from multi-morbidity (median comorbidities 2). Rheumatoid arthritis was the most frequent disease (34.1%), followed by spondyloarthritis (26.3%), connective tissue disease (21.1%) and vasculitis (11.2%). Most cases had an active disease (69.4%). Clinical presentation of COVID-19 was typical, with systemic symptoms (fever and asthenia) and respiratory symptoms. The overall outcome was severe, with high frequencies of hospitalisation (69.8%), respiratory support oxygen (55.7%), non-invasive ventilation (20.9%) or mechanical ventilation (7.5%), and 19% of deaths. Male patients typically manifested a worse prognosis. Immunomodulatory treatments were not significantly associated with an increased risk of intensive care unit admission/mechanical ventilation/death.</AbstractText>
<AbstractText Label="CONCLUSIONS">Although the report mainly includes the most severe cases, its temporal and spatial trend supports the validity of the national surveillance system. More complete data are being acquired in order to both test the hypothesis that RMD patients may have a different outcome from that of the general population and determine the safety of immunomodulatory treatments.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Scirè</LastName>
<ForeName>Carlo Alberto</ForeName>
<Initials>CA</Initials>
<AffiliationInfo><Affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, and Rheumatology Unit, Department of Medical Sciences, University of Ferrara, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carrara</LastName>
<ForeName>Greta</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zanetti</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, and Department of Statistics and Quantitative Methods, Division of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Landolfi</LastName>
<ForeName>Gianpiero</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chighizola</LastName>
<ForeName>Cecilia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Experimental Laboratory of Immunological and Rheumatologic Researches, Immunology and Rheumatology Unit, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alunno</LastName>
<ForeName>Alessia</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Andreoli</LastName>
<ForeName>Laura</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Rheumatology and Clinical Immunology Unit, ASST Spedali Civili; Department of Clinical and Experimental Sciences, University of Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Caporali</LastName>
<ForeName>Roberto</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Sciences and Community Health, University of Milan, ASST Pini CTO, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gerli</LastName>
<ForeName>Roberto</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sebastiani</LastName>
<ForeName>Gian Domenico</ForeName>
<Initials>GD</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Valesini</LastName>
<ForeName>Guido</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sinigaglia</LastName>
<ForeName>Luigi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Italian Society for Rheumatology, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>Italian Registry of the Italian Society for Rheumatology (CONTROL-19)</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>07</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Italy</Country>
<MedlineTA>Clin Exp Rheumatol</MedlineTA>
<NlmUniqueID>8308521</NlmUniqueID>
<ISSNLinking>0392-856X</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D062665" MajorTopicYN="N">Epidemiological Monitoring</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007558" MajorTopicYN="N" Type="Geographic">Italy</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012042" MajorTopicYN="N">Registries</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012216" MajorTopicYN="N">Rheumatic Diseases</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012219" MajorTopicYN="Y">Rheumatology</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<InvestigatorList><Investigator ValidYN="Y"><LastName>Alessandri</LastName>
<ForeName>Cristiano</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Baldissera</LastName>
<ForeName>Elena Marina</ForeName>
<Initials>EM</Initials>
<AffiliationInfo><Affiliation>Unità di Immunologia, Reumatologia, Immunologia e Malattie Rare, Ospedale San Raffaele, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Barsotti</LastName>
<ForeName>Simone</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bartoli</LastName>
<ForeName>Francesca</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Azienda Ospadaliero-Universitaria Careggi, Florence, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bartoloni</LastName>
<ForeName>Elena</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Benucci</LastName>
<ForeName>Maurizio</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ospedale S.Giovanni di Dio, Florence, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bergossi</LastName>
<ForeName>Francesca</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Ospedale di Cona, Ferrara, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bertolucci</LastName>
<ForeName>Daniela</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Sezione Reumatologia Ospedale Versilia, Lucca, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bettio</LastName>
<ForeName>Silvano</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Medicina 1, Ospedale Ca' Foncello, Treviso, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Biasi</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>University of Siena, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bonfanti</LastName>
<ForeName>Luigi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Ufficio Igiene ASL 2 "Marca Trevigiana", Regione Veneto, Treviso, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bortolotti</LastName>
<ForeName>Roberto</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>UO di Reumatologia, Ospedale S. Chiara, Trento, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bortoluzzi</LastName>
<ForeName>Alessandra</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Ospedale di Cona, Ferrara, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Campanaro</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Varese ASST Sette Laghi, Varese, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Campochiaro</LastName>
<ForeName>Corrado</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Unit of Internal Medicine and Clinical Immunology, IRCCS San Raffaele, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Canti</LastName>
<ForeName>Valentina</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Unit of Internal Medicine and Clinical Immunology, IRCCS San Raffaele, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Cappelli</LastName>
<ForeName>Antonella</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Varese ASST Sette Laghi, Varese, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Caprioli</LastName>
<ForeName>Marta</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Humanitas di Rozzano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Carboni</LastName>
<ForeName>Davide</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Azienda Ospadaliero-Universitaria Careggi, Florence, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Carletto</LastName>
<ForeName>Antonio</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia, AOUI Verona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Carlo-Stella</LastName>
<ForeName>Nicoletta</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Ospedale di Belluno, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Carraro</LastName>
<ForeName>Valeria</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Ospedale SS. Giovanni e Paolo, Venezia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Castelnovo</LastName>
<ForeName>Laura</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>ASST Ovest Milanese, Ospedale di Legnano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ceccarelli</LastName>
<ForeName>Fulvia</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Chimenti</LastName>
<ForeName>Maria Sole</ForeName>
<Initials>MS</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Cipolletta</LastName>
<ForeName>Edoardo</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Università Politecnica delle Marche, Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ciprian</LastName>
<ForeName>Manuela</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ospedale di Feltre, Belluno, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Conti</LastName>
<ForeName>Fabrizio</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Conticini</LastName>
<ForeName>Edoardo</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>University of Siena, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Crisafulli</LastName>
<ForeName>Francesca</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Crotti</LastName>
<ForeName>Chiara</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>ASST Gaetano Pini, CTO Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Cuomo</LastName>
<ForeName>Giovanna</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>UOC Medicina Interna, Università della Campania, Napoli, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Cutolo</LastName>
<ForeName>Maurizio</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>U.O.C. Clinica Reumatologica, Dipartimento Medicina Interna, Ospedale Policlinico San Martino, Genova, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Dantes</LastName>
<ForeName>Marcello</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ospedale San Carlo Borromeo, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Di Carlo</LastName>
<ForeName>Marco</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Università Politecnica delle Marche, Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Emmi</LastName>
<ForeName>Giacomo</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Azienda Ospadaliero-Universitaria Careggi, Florence, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Faggioli</LastName>
<ForeName>Paola</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>ASST Ovest Milanese, Ospedale di Legnano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Fiocco</LastName>
<ForeName>Ugo</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Dipartimento di Medicina DIMED, Universitò di Padova, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Franceschini</LastName>
<ForeName>Franco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Fredi</LastName>
<ForeName>Micaela</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gattamelata</LastName>
<ForeName>Angelica</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Policlinico Umberto I, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gerardi</LastName>
<ForeName>Maria Chiara</ForeName>
<Initials>MC</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Germanò</LastName>
<ForeName>Giuseppe</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Arcispedale S. Maria Nuova, Reggio Emilia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gerosa</LastName>
<ForeName>Maria</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>ASST Gaetano Pini, CTO Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Guidelli</LastName>
<ForeName>Giacomo</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Humanitas di Rozzano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Giollo</LastName>
<ForeName>Alessandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia, AOUI Verona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Greco</LastName>
<ForeName>Raffaella</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Reumatologia Gavardo, ASST del Garda, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Iannone</LastName>
<ForeName>Florenzo</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>A.O.U.C. Policlinico di Bari, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lazzaroni</LastName>
<ForeName>Maria Grazia</ForeName>
<Initials>MG</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lini</LastName>
<ForeName>Daniele</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lomater</LastName>
<ForeName>Claudia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>AO Ordine Mauriziano di Torino, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Longhi</LastName>
<ForeName>Matteo</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>U.O. Reumatologia, Istituto Ortopedico Galeazzi, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lurati</LastName>
<ForeName>Alfredomaria</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia Magenta ASST Ovest Milanese, Magenta, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Mastaglio</LastName>
<ForeName>Claudio</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Ospedale A. Manzoni, Lecco, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Moschetti</LastName>
<ForeName>Liala</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Nalli</LastName>
<ForeName>Cecilia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Olivo</LastName>
<ForeName>Domenico</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>ASP di Crotone, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Orsolini</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia, AOUI Verona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ossandon</LastName>
<ForeName>Alejandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Private practice, Rome, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Pacucci</LastName>
<ForeName>Viviana Antonella</ForeName>
<Initials>VA</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia, Policlinico Umberto I, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Panaro</LastName>
<ForeName>Salvatore</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Parisi</LastName>
<ForeName>Simone</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>SC Reumatologia, AOU Città della Salute e della Scienza, Torino, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Piantoni</LastName>
<ForeName>Silvia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Portuesi</LastName>
<ForeName>Maria Giovanna</ForeName>
<Initials>MG</Initials>
<AffiliationInfo><Affiliation>ASLTO3 Pinerolo, Torino, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Prandini</LastName>
<ForeName>Paolo</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Reumatologia Gavardo, ASST del Garda, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Quartuccio</LastName>
<ForeName>Luca</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, University of Udine, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Raffeiner</LastName>
<ForeName>Bernd</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Ospedale di Bolzano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Reggia</LastName>
<ForeName>Rossella</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Ospedale Maggiore di Cremona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Regola</LastName>
<ForeName>Francesca</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Riccieri</LastName>
<ForeName>Valeria</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Policlinico Umberto I, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Riva</LastName>
<ForeName>Marta</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ospedale San Gerardo, Monza, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Romeo</LastName>
<ForeName>Nicoletta</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>SSD Reumatologia, ASO Santa Croce e Carle, Cuneo, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Foti</LastName>
<ForeName>Rosario</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>UO Reumatologia, AO Policlinico San Marco, Catania, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Rossi</LastName>
<ForeName>Daniela</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>SS Reumatologia-CMID, Ospedale G. Bosco, Torino, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Rotondo</LastName>
<ForeName>Cinzia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>U.O.C. Reumatologia Universitaria, Policlinico Riuniti Foggia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Saccardo</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Ospedale di Saronno, Varese, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Salaffi</LastName>
<ForeName>Fausto</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Università Politecnica delle Marche, Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Sartorelli</LastName>
<ForeName>Silvia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>IRCCS San Raffaele, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Sarzi Puttini</LastName>
<ForeName>Piercarlo</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>ASST Ospedale Fatebenefratelli-Sacco, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Saviola</LastName>
<ForeName>Gianantonio</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>ICS Maugeru IRCCS, Castel Goffredo, Mantova, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Scarpa</LastName>
<ForeName>Raffaele</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>UOC Reumatologia, Università di Napoli Federico II, Napoli, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Scotti</LastName>
<ForeName>Isabella</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>ASST Gaetano Pini, CTO Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Silvagni</LastName>
<ForeName>Ettore</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Ospedale di Cona, Ferrara, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Silveri</LastName>
<ForeName>Ferdinando</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Università Politecnica delle Marche, Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Spinelli</LastName>
<ForeName>Francesca Romana</ForeName>
<Initials>FR</Initials>
<AffiliationInfo><Affiliation>Rheumatology, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Tardella</LastName>
<ForeName>Marika</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Università Politecnica delle Marche, Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Tinazzi</LastName>
<ForeName>Ilaria</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>IRCCS Ospedale Sacro Cuore Negrar, Verona, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Tirri</LastName>
<ForeName>Enrico</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>UO Reumatologia, Ospedale San Giovanni Bosco, Napoli, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Todoerti</LastName>
<ForeName>Monica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>AON di Alessandria, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ubiali</LastName>
<ForeName>Tania</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>ASST Gaetano Pini, CTO Milano, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Vadacca</LastName>
<ForeName>Marta</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Università Campus Bio-Medico, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Varisco</LastName>
<ForeName>Valentina</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Ospedale San Gerardo, Monza, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Zabotti</LastName>
<ForeName>Alen</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, University of Udine, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Zandonella Callegher</LastName>
<ForeName>Sara</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Rheumatology Unit, University of Udine, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Zanframundo</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>IRCCS Policlinico San Matteo, Pavia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Zingarelli</LastName>
<ForeName>Stefania</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>ASST Spedali Civili, Brescia, Italy.</Affiliation>
</AffiliationInfo>
</Investigator>
</InvestigatorList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>05</Month>
<Day>28</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>06</Month>
<Day>14</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>7</Month>
<Day>30</Day>
<Hour>6</Hour>
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