Hydroxychloroquine is no miracle cure for covid-19 infection -imaging and clinical course in an elderly female.
Identifieur interne : 000793 ( Main/Corpus ); précédent : 000792; suivant : 000794Hydroxychloroquine is no miracle cure for covid-19 infection -imaging and clinical course in an elderly female.
Auteurs : Igor Alexander Harsch ; Marcin Skiba ; Eric Lopatta ; Peter Christopher KonturekSource :
- Wiadomosci lekarskie (Warsaw, Poland : 1960) [ 0043-5147 ] ; 2020.
English descriptors
- KwdEn :
- MESH :
- chemical : Hydroxychloroquine.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- Aged, Betacoronavirus, Female, Humans, Pandemics.
Abstract
The risk for an unfavourable course of SARS-CoV-2 pneumonia rises with age and comorbidities. We report the case of an elderly female where the sum of such factors - together with massive findings in the computed tomography of the lung - led us to a therapy with hydroxychloroquine as a compassionate use. The unfavourable outcome demonstrates that - despite the enthusiasm of some authors - hydroxychloroquine is no miracle drug. The worldwide SOLIDARITY trial will help clinicians to assess the potential of the repurposed antimalarial drugs better.
PubMed: 32759459
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We report the case of an elderly female where the sum of such factors - together with massive findings in the computed tomography of the lung - led us to a therapy with hydroxychloroquine as a compassionate use. The unfavourable outcome demonstrates that - despite the enthusiasm of some authors - hydroxychloroquine is no miracle drug. The worldwide SOLIDARITY trial will help clinicians to assess the potential of the repurposed antimalarial drugs better.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32759459</PMID><DateCompleted><Year>2020</Year><Month>08</Month><Day>11</Day></DateCompleted><DateRevised><Year>2020</Year><Month>08</Month><Day>11</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0043-5147</ISSN><JournalIssue CitedMedium="Print"><Volume>73</Volume><Issue>7</Issue><PubDate><Year>2020</Year></PubDate></JournalIssue><Title>Wiadomosci lekarskie (Warsaw, Poland : 1960)</Title><ISOAbbreviation>Wiad Lek</ISOAbbreviation></Journal><ArticleTitle>Hydroxychloroquine is no miracle cure for covid-19 infection -imaging and clinical course in an elderly female.</ArticleTitle><Pagination><MedlinePgn>1583-1585</MedlinePgn></Pagination><Abstract><AbstractText>The risk for an unfavourable course of SARS-CoV-2 pneumonia rises with age and comorbidities. We report the case of an elderly female where the sum of such factors - together with massive findings in the computed tomography of the lung - led us to a therapy with hydroxychloroquine as a compassionate use. The unfavourable outcome demonstrates that - despite the enthusiasm of some authors - hydroxychloroquine is no miracle drug. The worldwide SOLIDARITY trial will help clinicians to assess the potential of the repurposed antimalarial drugs better.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Harsch</LastName><ForeName>Igor Alexander</ForeName><Initials>IA</Initials><AffiliationInfo><Affiliation>Department Of Internal Medicine II, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Skiba</LastName><ForeName>Marcin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department Of Internal Medicine II, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lopatta</LastName><ForeName>Eric</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department Of Radiology, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Konturek</LastName><ForeName>Peter Christopher</ForeName><Initials>PC</Initials><AffiliationInfo><Affiliation>Department Of Internal Medicine II, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Poland</Country><MedlineTA>Wiad Lek</MedlineTA><NlmUniqueID>9705467</NlmUniqueID><ISSNLinking>0043-5147</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Protocol" UI="C000705127">COVID-19 drug treatment</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N"> COVID-19</Keyword><Keyword MajorTopicYN="N"> Chloroquine</Keyword><Keyword MajorTopicYN="N"> Hydroxychloroquine</Keyword><Keyword MajorTopicYN="N"> SARS-CoV-2</Keyword><Keyword MajorTopicYN="N"> chest CT</Keyword><Keyword MajorTopicYN="N"> compassionate use</Keyword><Keyword MajorTopicYN="N"> repurposed agent</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32759459</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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