ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.
Identifieur interne : 000666 ( Main/Corpus ); précédent : 000665; suivant : 000667ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.
Auteurs : Mario Gramegna ; Luca Baldetti ; Alessandro Beneduce ; Luigi Pannone ; Giulio Falasconi ; Francesco Calvo ; Vittorio Pazzanese ; Stefania Sacchi ; Matteo Pagnesi ; Francesco Moroni ; Silvia Ajello ; Giulio Melisurgo ; Eustachio Agricola ; Paolo G. Camici ; Anna Mara Scandroglio ; Giovanni Landoni ; Fabio Ciceri ; Alberto Zangrillo ; Alberto Maria CappellettiSource :
- Circulation. Cardiovascular interventions [ 1941-7632 ] ; 2020.
English descriptors
- KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (complications), Coronavirus Infections (epidemiology), Female (MeSH), Humans (MeSH), Italy (epidemiology), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Percutaneous Coronary Intervention (methods), Pneumonia, Viral (complications), Pneumonia, Viral (epidemiology), Prospective Studies (MeSH), Public Health Practice (MeSH), Registries (MeSH), ST Elevation Myocardial Infarction (complications), ST Elevation Myocardial Infarction (surgery).
- MESH :
- geographic , epidemiology : Italy.
- complications : Coronavirus Infections, Pneumonia, Viral, ST Elevation Myocardial Infarction.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- methods : Percutaneous Coronary Intervention.
- surgery : ST Elevation Myocardial Infarction.
- Aged, Betacoronavirus, Female, Humans, Male, Middle Aged, Pandemics, Prospective Studies, Public Health Practice, Registries.
Abstract
BACKGROUND
Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.
METHODS
This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.
RESULTS
A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours;
CONCLUSIONS
These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.
DOI: 10.1161/CIRCINTERVENTIONS.120.009413
PubMed: 32791953
Links to Exploration step
pubmed:32791953Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.</title><author><name sortKey="Gramegna, Mario" sort="Gramegna, Mario" uniqKey="Gramegna M" first="Mario" last="Gramegna">Mario Gramegna</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Baldetti, Luca" sort="Baldetti, Luca" uniqKey="Baldetti L" first="Luca" last="Baldetti">Luca Baldetti</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Beneduce, Alessandro" sort="Beneduce, Alessandro" uniqKey="Beneduce A" first="Alessandro" last="Beneduce">Alessandro Beneduce</name><affiliation><nlm:affiliation>Interventional Cardiology Unit (A.B.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pannone, Luigi" sort="Pannone, Luigi" uniqKey="Pannone L" first="Luigi" last="Pannone">Luigi Pannone</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Falasconi, Giulio" sort="Falasconi, Giulio" uniqKey="Falasconi G" first="Giulio" last="Falasconi">Giulio Falasconi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Calvo, Francesco" sort="Calvo, Francesco" uniqKey="Calvo F" first="Francesco" last="Calvo">Francesco Calvo</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pazzanese, Vittorio" sort="Pazzanese, Vittorio" uniqKey="Pazzanese V" first="Vittorio" last="Pazzanese">Vittorio Pazzanese</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Sacchi, Stefania" sort="Sacchi, Stefania" uniqKey="Sacchi S" first="Stefania" last="Sacchi">Stefania Sacchi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pagnesi, Matteo" sort="Pagnesi, Matteo" uniqKey="Pagnesi M" first="Matteo" last="Pagnesi">Matteo Pagnesi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Moroni, Francesco" sort="Moroni, Francesco" uniqKey="Moroni F" first="Francesco" last="Moroni">Francesco Moroni</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ajello, Silvia" sort="Ajello, Silvia" uniqKey="Ajello S" first="Silvia" last="Ajello">Silvia Ajello</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Melisurgo, Giulio" sort="Melisurgo, Giulio" uniqKey="Melisurgo G" first="Giulio" last="Melisurgo">Giulio Melisurgo</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Agricola, Eustachio" sort="Agricola, Eustachio" uniqKey="Agricola E" first="Eustachio" last="Agricola">Eustachio Agricola</name><affiliation><nlm:affiliation>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Camici, Paolo G" sort="Camici, Paolo G" uniqKey="Camici P" first="Paolo G" last="Camici">Paolo G. Camici</name><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Scandroglio, Anna Mara" sort="Scandroglio, Anna Mara" uniqKey="Scandroglio A" first="Anna Mara" last="Scandroglio">Anna Mara Scandroglio</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name><affiliation><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Ciceri, Fabio" sort="Ciceri, Fabio" uniqKey="Ciceri F" first="Fabio" last="Ciceri">Fabio Ciceri</name><affiliation><nlm:affiliation>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Zangrillo, Alberto" sort="Zangrillo, Alberto" uniqKey="Zangrillo A" first="Alberto" last="Zangrillo">Alberto Zangrillo</name><affiliation><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Cappelletti, Alberto Maria" sort="Cappelletti, Alberto Maria" uniqKey="Cappelletti A" first="Alberto Maria" last="Cappelletti">Alberto Maria Cappelletti</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32791953</idno><idno type="pmid">32791953</idno><idno type="doi">10.1161/CIRCINTERVENTIONS.120.009413</idno><idno type="wicri:Area/Main/Corpus">000666</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000666</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.</title><author><name sortKey="Gramegna, Mario" sort="Gramegna, Mario" uniqKey="Gramegna M" first="Mario" last="Gramegna">Mario Gramegna</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Baldetti, Luca" sort="Baldetti, Luca" uniqKey="Baldetti L" first="Luca" last="Baldetti">Luca Baldetti</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Beneduce, Alessandro" sort="Beneduce, Alessandro" uniqKey="Beneduce A" first="Alessandro" last="Beneduce">Alessandro Beneduce</name><affiliation><nlm:affiliation>Interventional Cardiology Unit (A.B.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pannone, Luigi" sort="Pannone, Luigi" uniqKey="Pannone L" first="Luigi" last="Pannone">Luigi Pannone</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Falasconi, Giulio" sort="Falasconi, Giulio" uniqKey="Falasconi G" first="Giulio" last="Falasconi">Giulio Falasconi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Calvo, Francesco" sort="Calvo, Francesco" uniqKey="Calvo F" first="Francesco" last="Calvo">Francesco Calvo</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pazzanese, Vittorio" sort="Pazzanese, Vittorio" uniqKey="Pazzanese V" first="Vittorio" last="Pazzanese">Vittorio Pazzanese</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Sacchi, Stefania" sort="Sacchi, Stefania" uniqKey="Sacchi S" first="Stefania" last="Sacchi">Stefania Sacchi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pagnesi, Matteo" sort="Pagnesi, Matteo" uniqKey="Pagnesi M" first="Matteo" last="Pagnesi">Matteo Pagnesi</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Moroni, Francesco" sort="Moroni, Francesco" uniqKey="Moroni F" first="Francesco" last="Moroni">Francesco Moroni</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ajello, Silvia" sort="Ajello, Silvia" uniqKey="Ajello S" first="Silvia" last="Ajello">Silvia Ajello</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Melisurgo, Giulio" sort="Melisurgo, Giulio" uniqKey="Melisurgo G" first="Giulio" last="Melisurgo">Giulio Melisurgo</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Agricola, Eustachio" sort="Agricola, Eustachio" uniqKey="Agricola E" first="Eustachio" last="Agricola">Eustachio Agricola</name><affiliation><nlm:affiliation>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Camici, Paolo G" sort="Camici, Paolo G" uniqKey="Camici P" first="Paolo G" last="Camici">Paolo G. Camici</name><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Scandroglio, Anna Mara" sort="Scandroglio, Anna Mara" uniqKey="Scandroglio A" first="Anna Mara" last="Scandroglio">Anna Mara Scandroglio</name><affiliation><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name><affiliation><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Ciceri, Fabio" sort="Ciceri, Fabio" uniqKey="Ciceri F" first="Fabio" last="Ciceri">Fabio Ciceri</name><affiliation><nlm:affiliation>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Zangrillo, Alberto" sort="Zangrillo, Alberto" uniqKey="Zangrillo A" first="Alberto" last="Zangrillo">Alberto Zangrillo</name><affiliation><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation></affiliation></author><author><name sortKey="Cappelletti, Alberto Maria" sort="Cappelletti, Alberto Maria" uniqKey="Cappelletti A" first="Alberto Maria" last="Cappelletti">Alberto Maria Cappelletti</name><affiliation><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Circulation. Cardiovascular interventions</title><idno type="eISSN">1941-7632</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (epidemiology)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Italy (epidemiology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Percutaneous Coronary Intervention (methods)</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (epidemiology)</term><term>Prospective Studies (MeSH)</term><term>Public Health Practice (MeSH)</term><term>Registries (MeSH)</term><term>ST Elevation Myocardial Infarction (complications)</term><term>ST Elevation Myocardial Infarction (surgery)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Italy</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term><term>ST Elevation Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Percutaneous Coronary Intervention</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>ST Elevation Myocardial Infarction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Betacoronavirus</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Prospective Studies</term><term>Public Health Practice</term><term>Registries</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours; </p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32791953</PMID><DateCompleted><Year>2020</Year><Month>08</Month><Day>27</Day></DateCompleted><DateRevised><Year>2020</Year><Month>08</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1941-7632</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><Issue>8</Issue><PubDate><Year>2020</Year><Month>08</Month></PubDate></JournalIssue><Title>Circulation. Cardiovascular interventions</Title><ISOAbbreviation>Circ Cardiovasc Interv</ISOAbbreviation></Journal><ArticleTitle>ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.</ArticleTitle><Pagination><MedlinePgn>e009413</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1161/CIRCINTERVENTIONS.120.009413</ELocationID><Abstract><AbstractText Label="BACKGROUND">Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.</AbstractText><AbstractText Label="METHODS">This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.</AbstractText><AbstractText Label="RESULTS">A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours; <i>P</i><0.01). A higher proportion of patients presenting with late presentation STEMI was observed in 2020 compared with the historical cohort (50.0% versus 4.8%; <i>P</i><0.01). Primary percutaneous coronary intervention resulted indicated in 80.8% of patients in 2020 compared with 100% in the historical cohort (<i>P</i>=0.06). In-hospital death, thromboembolism, mechanical ventilation, or hemodynamic decompensation needing inotropic or mechanical support were similar between years.</AbstractText><AbstractText Label="CONCLUSIONS">These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gramegna</LastName><ForeName>Mario</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baldetti</LastName><ForeName>Luca</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beneduce</LastName><ForeName>Alessandro</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Interventional Cardiology Unit (A.B.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pannone</LastName><ForeName>Luigi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Falasconi</LastName><ForeName>Giulio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Calvo</LastName><ForeName>Francesco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pazzanese</LastName><ForeName>Vittorio</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sacchi</LastName><ForeName>Stefania</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pagnesi</LastName><ForeName>Matteo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moroni</LastName><ForeName>Francesco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ajello</LastName><ForeName>Silvia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Melisurgo</LastName><ForeName>Giulio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Agricola</LastName><ForeName>Eustachio</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Camici</LastName><ForeName>Paolo G</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scandroglio</LastName><ForeName>Anna Mara</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Landoni</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ciceri</LastName><ForeName>Fabio</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zangrillo</LastName><ForeName>Alberto</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cappelletti</LastName><ForeName>Alberto Maria</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>14</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Circ Cardiovasc Interv</MedlineTA><NlmUniqueID>101499602</NlmUniqueID><ISSNLinking>1941-7640</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007558" MajorTopicYN="N" Type="Geographic">Italy</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062645" MajorTopicYN="N">Percutaneous Coronary Intervention</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015980" MajorTopicYN="Y">Public Health Practice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012042" MajorTopicYN="Y">Registries</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000072657" MajorTopicYN="N">ST Elevation Myocardial Infarction</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">acute coronary syndrome</Keyword><Keyword MajorTopicYN="Y">coronavirus</Keyword><Keyword MajorTopicYN="Y">myocardial infarction</Keyword><Keyword MajorTopicYN="Y">pandemic</Keyword><Keyword MajorTopicYN="Y">severe acute respiratory syndrome coronavirus 2</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32791953</ArticleId><ArticleId IdType="doi">10.1161/CIRCINTERVENTIONS.120.009413</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidSeniorV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000666 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000666 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidSeniorV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= pubmed:32791953
|texte= ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Corpus/RBID.i -Sk "pubmed:32791953" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a CovidSeniorV1
| This area was generated with Dilib version V0.6.37. |  |