Universal laboratory testing for SARS-CoV-2 in hyperacute stroke during the COVID-19 pandemic.
Identifieur interne : 000607 ( Main/Corpus ); précédent : 000606; suivant : 000608Universal laboratory testing for SARS-CoV-2 in hyperacute stroke during the COVID-19 pandemic.
Auteurs : Kristian Barlinn ; Timo Siepmann ; Lars-Peder Pallesen ; Simon Winzer ; Annahita Sedghi ; Percy Schroettner ; Kristina Hochauf-Stange ; Alexandra Prakapenia ; Haidar Moustafa ; Katja De With ; Jennifer Linn ; Heinz Reichmann ; Jessica Barlinn ; Volker PuetzSource :
- Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [ 1532-8511 ] ; 2020.
English descriptors
- KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (isolation & purification), Clinical Decision-Making (MeSH), Clinical Laboratory Techniques (MeSH), Coronavirus Infections (complications), Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Coronavirus Infections (virology), Emergency Service, Hospital (MeSH), Female (MeSH), Humans (MeSH), Infection Control (MeSH), Male (MeSH), Pandemics (MeSH), Patient Safety (MeSH), Patient Selection (MeSH), Pneumonia, Viral (complications), Pneumonia, Viral (diagnosis), Pneumonia, Viral (therapy), Pneumonia, Viral (virology), Predictive Value of Tests (MeSH), Prospective Studies (MeSH), Risk Factors (MeSH), Stroke (complications), Stroke (diagnosis), Stroke (therapy).
- MESH :
- complications : Coronavirus Infections, Pneumonia, Viral, Stroke.
- diagnosis : Coronavirus Infections, Pneumonia, Viral, Stroke.
- isolation & purification : Betacoronavirus.
- therapy : Coronavirus Infections, Pneumonia, Viral, Stroke.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Aged, Aged, 80 and over, Clinical Decision-Making, Clinical Laboratory Techniques, Emergency Service, Hospital, Female, Humans, Infection Control, Male, Pandemics, Patient Safety, Patient Selection, Predictive Value of Tests, Prospective Studies, Risk Factors.
Abstract
OBJECTIVE
Stroke patients are thought to be at increased risk of Coronavirus Disease 2019 (COVID-19). To evaluate yield of universal laboratory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in acute stroke patients and its impact on hyperacute stroke care.
METHODS
Between weeks 14 and 18 in 2020, a protected code stroke protocol including infection control screening and laboratory testing for SARS-CoV-2 was prospectively implemented for all code stroke patients upon arrival to the emergency department. If infection control screen was positive, patients received protective hygienic measures and laboratory test results were available within four hours from testing. In patients with negative screen, laboratory results were available no later than the next working day. Door-to-imaging times of patients treated with thrombolysis or thrombectomy were compared with those of patients treated during the preceding weeks 1 to 13 in 2020.
RESULTS
During the 4-weeks study period, 116 consecutive code stroke patients underwent infection control screen and laboratory testing for SARS-CoV-2. Among 5 (4.3%) patients whose infection control screen was positive, no patient was tested positive for SARS-CoV-2. All patients with negative infection control screens had negative test results. Door-to-imaging times of patients treated with thrombolysis and/or thrombectomy were not different to those treated during the preceding weeks (12 [9-15] min versus 13 [11-17] min, p = 0.24).
CONCLUSIONS
Universal laboratory testing for SARS-CoV-2 provided useful information on patients' infection status and its implementation into a protected code stroke protocol did not adversely affect hyperacute stroke care.
DOI: 10.1016/j.jstrokecerebrovasdis.2020.105061
PubMed: 32807466
PubMed Central: PMC7305910
Links to Exploration step
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<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: kristian.barlinn@ukdd.de.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: timo.siepmann@ukdd.de.</nlm:affiliation>
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<author><name sortKey="Sedghi, Annahita" sort="Sedghi, Annahita" uniqKey="Sedghi A" first="Annahita" last="Sedghi">Annahita Sedghi</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: annahita.sedghi@ukdd.de.</nlm:affiliation>
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<author><name sortKey="Schroettner, Percy" sort="Schroettner, Percy" uniqKey="Schroettner P" first="Percy" last="Schroettner">Percy Schroettner</name>
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<author><name sortKey="Hochauf Stange, Kristina" sort="Hochauf Stange, Kristina" uniqKey="Hochauf Stange K" first="Kristina" last="Hochauf-Stange">Kristina Hochauf-Stange</name>
<affiliation><nlm:affiliation>Department of Virology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: Kristina.Hochauf-Stange@uniklinikum-dresden.de.</nlm:affiliation>
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</author>
<author><name sortKey="Prakapenia, Alexandra" sort="Prakapenia, Alexandra" uniqKey="Prakapenia A" first="Alexandra" last="Prakapenia">Alexandra Prakapenia</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: alexandra.prakapenia@ukdd.de.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Moustafa, Haidar" sort="Moustafa, Haidar" uniqKey="Moustafa H" first="Haidar" last="Moustafa">Haidar Moustafa</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: haidar.moustafa@ukdd.de.</nlm:affiliation>
</affiliation>
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<author><name sortKey="De With, Katja" sort="De With, Katja" uniqKey="De With K" first="Katja" last="De With">Katja De With</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: katja.dewith@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Linn, Jennifer" sort="Linn, Jennifer" uniqKey="Linn J" first="Jennifer" last="Linn">Jennifer Linn</name>
<affiliation><nlm:affiliation>Institute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: jennifer.linn@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: heinz.reichmann@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Barlinn, Jessica" sort="Barlinn, Jessica" uniqKey="Barlinn J" first="Jessica" last="Barlinn">Jessica Barlinn</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: jessica.barlinn@ukdd.de.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Puetz, Volker" sort="Puetz, Volker" uniqKey="Puetz V" first="Volker" last="Puetz">Volker Puetz</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: volker.puetz@ukdd.de.</nlm:affiliation>
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<author><name sortKey="Pallesen, Lars Peder" sort="Pallesen, Lars Peder" uniqKey="Pallesen L" first="Lars-Peder" last="Pallesen">Lars-Peder Pallesen</name>
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<author><name sortKey="Winzer, Simon" sort="Winzer, Simon" uniqKey="Winzer S" first="Simon" last="Winzer">Simon Winzer</name>
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</affiliation>
</author>
<author><name sortKey="Sedghi, Annahita" sort="Sedghi, Annahita" uniqKey="Sedghi A" first="Annahita" last="Sedghi">Annahita Sedghi</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: annahita.sedghi@ukdd.de.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Schroettner, Percy" sort="Schroettner, Percy" uniqKey="Schroettner P" first="Percy" last="Schroettner">Percy Schroettner</name>
<affiliation><nlm:affiliation>Department of Virology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: percy.schroettner@tu-dresden.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hochauf Stange, Kristina" sort="Hochauf Stange, Kristina" uniqKey="Hochauf Stange K" first="Kristina" last="Hochauf-Stange">Kristina Hochauf-Stange</name>
<affiliation><nlm:affiliation>Department of Virology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: Kristina.Hochauf-Stange@uniklinikum-dresden.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Prakapenia, Alexandra" sort="Prakapenia, Alexandra" uniqKey="Prakapenia A" first="Alexandra" last="Prakapenia">Alexandra Prakapenia</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: alexandra.prakapenia@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Moustafa, Haidar" sort="Moustafa, Haidar" uniqKey="Moustafa H" first="Haidar" last="Moustafa">Haidar Moustafa</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: haidar.moustafa@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="De With, Katja" sort="De With, Katja" uniqKey="De With K" first="Katja" last="De With">Katja De With</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: katja.dewith@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Linn, Jennifer" sort="Linn, Jennifer" uniqKey="Linn J" first="Jennifer" last="Linn">Jennifer Linn</name>
<affiliation><nlm:affiliation>Institute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: jennifer.linn@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: heinz.reichmann@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Barlinn, Jessica" sort="Barlinn, Jessica" uniqKey="Barlinn J" first="Jessica" last="Barlinn">Jessica Barlinn</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: jessica.barlinn@ukdd.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Puetz, Volker" sort="Puetz, Volker" uniqKey="Puetz V" first="Volker" last="Puetz">Volker Puetz</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: volker.puetz@ukdd.de.</nlm:affiliation>
</affiliation>
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<series><title level="j">Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association</title>
<idno type="eISSN">1532-8511</idno>
<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Clinical Decision-Making (MeSH)</term>
<term>Clinical Laboratory Techniques (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Coronavirus Infections (virology)</term>
<term>Emergency Service, Hospital (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Infection Control (MeSH)</term>
<term>Male (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Patient Safety (MeSH)</term>
<term>Patient Selection (MeSH)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (therapy)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Predictive Value of Tests (MeSH)</term>
<term>Prospective Studies (MeSH)</term>
<term>Risk Factors (MeSH)</term>
<term>Stroke (complications)</term>
<term>Stroke (diagnosis)</term>
<term>Stroke (therapy)</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Clinical Decision-Making</term>
<term>Clinical Laboratory Techniques</term>
<term>Emergency Service, Hospital</term>
<term>Female</term>
<term>Humans</term>
<term>Infection Control</term>
<term>Male</term>
<term>Pandemics</term>
<term>Patient Safety</term>
<term>Patient Selection</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>Stroke patients are thought to be at increased risk of Coronavirus Disease 2019 (COVID-19). To evaluate yield of universal laboratory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in acute stroke patients and its impact on hyperacute stroke care.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Between weeks 14 and 18 in 2020, a protected code stroke protocol including infection control screening and laboratory testing for SARS-CoV-2 was prospectively implemented for all code stroke patients upon arrival to the emergency department. If infection control screen was positive, patients received protective hygienic measures and laboratory test results were available within four hours from testing. In patients with negative screen, laboratory results were available no later than the next working day. Door-to-imaging times of patients treated with thrombolysis or thrombectomy were compared with those of patients treated during the preceding weeks 1 to 13 in 2020.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>During the 4-weeks study period, 116 consecutive code stroke patients underwent infection control screen and laboratory testing for SARS-CoV-2. Among 5 (4.3%) patients whose infection control screen was positive, no patient was tested positive for SARS-CoV-2. All patients with negative infection control screens had negative test results. Door-to-imaging times of patients treated with thrombolysis and/or thrombectomy were not different to those treated during the preceding weeks (12 [9-15] min versus 13 [11-17] min, p = 0.24).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Universal laboratory testing for SARS-CoV-2 provided useful information on patients' infection status and its implementation into a protected code stroke protocol did not adversely affect hyperacute stroke care.</p>
</div>
</front>
</TEI>
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<DateCompleted><Year>2020</Year>
<Month>08</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>10</Month>
<Day>03</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-8511</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>29</Volume>
<Issue>9</Issue>
<PubDate><Year>2020</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association</Title>
<ISOAbbreviation>J Stroke Cerebrovasc Dis</ISOAbbreviation>
</Journal>
<ArticleTitle>Universal laboratory testing for SARS-CoV-2 in hyperacute stroke during the COVID-19 pandemic.</ArticleTitle>
<Pagination><MedlinePgn>105061</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jstrokecerebrovasdis.2020.105061</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Stroke patients are thought to be at increased risk of Coronavirus Disease 2019 (COVID-19). To evaluate yield of universal laboratory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in acute stroke patients and its impact on hyperacute stroke care.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Between weeks 14 and 18 in 2020, a protected code stroke protocol including infection control screening and laboratory testing for SARS-CoV-2 was prospectively implemented for all code stroke patients upon arrival to the emergency department. If infection control screen was positive, patients received protective hygienic measures and laboratory test results were available within four hours from testing. In patients with negative screen, laboratory results were available no later than the next working day. Door-to-imaging times of patients treated with thrombolysis or thrombectomy were compared with those of patients treated during the preceding weeks 1 to 13 in 2020.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">During the 4-weeks study period, 116 consecutive code stroke patients underwent infection control screen and laboratory testing for SARS-CoV-2. Among 5 (4.3%) patients whose infection control screen was positive, no patient was tested positive for SARS-CoV-2. All patients with negative infection control screens had negative test results. Door-to-imaging times of patients treated with thrombolysis and/or thrombectomy were not different to those treated during the preceding weeks (12 [9-15] min versus 13 [11-17] min, p = 0.24).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Universal laboratory testing for SARS-CoV-2 provided useful information on patients' infection status and its implementation into a protected code stroke protocol did not adversely affect hyperacute stroke care.</AbstractText>
<CopyrightInformation>Copyright © 2020 Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barlinn</LastName>
<ForeName>Kristian</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: kristian.barlinn@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Siepmann</LastName>
<ForeName>Timo</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: timo.siepmann@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pallesen</LastName>
<ForeName>Lars-Peder</ForeName>
<Initials>LP</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: lars.peder-pallesen@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Winzer</LastName>
<ForeName>Simon</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: simon.winzer@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sedghi</LastName>
<ForeName>Annahita</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: annahita.sedghi@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schroettner</LastName>
<ForeName>Percy</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Virology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: percy.schroettner@tu-dresden.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hochauf-Stange</LastName>
<ForeName>Kristina</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Virology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: Kristina.Hochauf-Stange@uniklinikum-dresden.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Prakapenia</LastName>
<ForeName>Alexandra</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: alexandra.prakapenia@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moustafa</LastName>
<ForeName>Haidar</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: haidar.moustafa@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de With</LastName>
<ForeName>Katja</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Division of Infectious Diseases, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: katja.dewith@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Linn</LastName>
<ForeName>Jennifer</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Institute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address: jennifer.linn@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Reichmann</LastName>
<ForeName>Heinz</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: heinz.reichmann@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barlinn</LastName>
<ForeName>Jessica</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: jessica.barlinn@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Puetz</LastName>
<ForeName>Volker</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany. Electronic address: volker.puetz@ukdd.de.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>06</Month>
<Day>20</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Stroke Cerebrovasc Dis</MedlineTA>
<NlmUniqueID>9111633</NlmUniqueID>
<ISSNLinking>1052-3057</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Protocol" UI="C000657964">COVID-19 diagnostic testing</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000066491" MajorTopicYN="N">Clinical Decision-Making</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019411" MajorTopicYN="Y">Clinical Laboratory Techniques</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004636" MajorTopicYN="N">Emergency Service, Hospital</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017053" MajorTopicYN="N">Infection Control</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D061214" MajorTopicYN="N">Patient Safety</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018579" MajorTopicYN="N">Patient Selection</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020521" MajorTopicYN="N">Stroke</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Acute Stroke</Keyword>
<Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">Patient safety</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV-2</Keyword>
<Keyword MajorTopicYN="N">Stroke protocol</Keyword>
</KeywordList>
<CoiStatement>Declaration of Competing Interests The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.</CoiStatement>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>05</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2020</Year>
<Month>06</Month>
<Day>07</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>06</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>8</Month>
<Day>19</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>8</Month>
<Day>19</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>8</Month>
<Day>25</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32807466</ArticleId>
<ArticleId IdType="pii">S1052-3057(20)30479-1</ArticleId>
<ArticleId IdType="doi">10.1016/j.jstrokecerebrovasdis.2020.105061</ArticleId>
<ArticleId IdType="pmc">PMC7305910</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
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