CovidSeniorV1, Main, Corpus, bibRecord, 000449

Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China.

Identifieur interne : 000449 ( Main/Corpus ); précédent : 000448; suivant : 000450

Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China.

Auteurs : Chaowei Li ; Qingshi Chen ; Jianwen Wang ; Huasong Lin ; Yalan Lin ; Jinhuang Lin ; Fangzhan Peng ; Jiangmu Chen ; Zhirong Yang

Source :

Aging [ 1945-4589 ] ; 2020.

RBID : pubmed:32855361

English descriptors

KwdEn :
- Aged (MeSH), Betacoronavirus (isolation & purification), China (epidemiology), Comorbidity (MeSH), Coronavirus Infections (blood), Coronavirus Infections (mortality), Coronavirus Infections (physiopathology), Coronavirus Infections (therapy), Female (MeSH), Humans (MeSH), Length of Stay (statistics & numerical data), Leukocyte Count (methods), Liver Diseases (diagnosis), Liver Diseases (epidemiology), Lymphocytes (MeSH), Male (MeSH), Middle Aged (MeSH), Mortality (MeSH), Neutrophils (MeSH), Pandemics (MeSH), Pneumonia, Viral (blood), Pneumonia, Viral (mortality), Pneumonia, Viral (physiopathology), Pneumonia, Viral (therapy), Prognosis (MeSH), Retrospective Studies (MeSH), Severity of Illness Index (MeSH).
MESH :
- geographic , epidemiology : China.
- blood : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Liver Diseases.
- epidemiology : Liver Diseases.
- isolation & purification : Betacoronavirus.
- methods : Leukocyte Count.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- physiopathology : Coronavirus Infections, Pneumonia, Viral.
- statistics & numerical data : Length of Stay.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- Aged, Comorbidity, Female, Humans, Lymphocytes, Male, Middle Aged, Mortality, Neutrophils, Pandemics, Prognosis, Retrospective Studies, Severity of Illness Index.

Abstract

BACKGROUND

Previous work has described acute liver injury (ALI) in coronavirus disease 2019 (COVID-19) pneumonia patients, However, there is limited analyses available investigating chronic liver disease (CLD) in COVID-19 patients. This study aimed to investigate clinical characteristics and outcomes of CLD confirmed in COVID-19 patients.

RESULTS

A total of 104 cases (each group containing 52 patients) were analyzed in this study. The CLD group showed an average of 14 (10.0~21.2) length of stay (LOS) days, compared to the group without CLD that only showed an average of 12.5 (10~16) LOS days (Relative Risk [RR] = 1.34, 95% CI (1.22~1.48), P<0.001; Adjusted Relative Risk was 1.24 (95% CI: 1.12~1.39)). The CLD group contained a higher mortality rate and slight liver injury. Furthermore, COX regression model analyses suggested that the neutrophil-to-lymphocyte ratio (NLR) was an independent predictor of mortality risk (P < 0.001) in the CLD group. Additionally, a high NLR significantly correlated with a shorter overall survival (P <0.001).

CONCLUSIONS

COVID-19 patients also diagnosed with CLD suffered longer LOS, slight liver injuries and a higher mortality when compared to COVID-19 patients without CLD. The NLR was an independent risk factor for in-hospital deaths. Increased expression of NLR was an indicator of poor prognosis in COVID-19 patients with CLD. Thus, COVID-19 patients diagnosed with CLD and who show a higher NLR need additional care.

METHODS

A retrospective cohort study was performed at the Wuhan Jin Yin-tan Hospital from February 2, 2020 to April 2, 2020. COVID-19 patients diagnosed with CLD or not diagnosed with CLD were enrolled in this study. The clinical characteristics and outcomes of these patients were compared.

DOI: 10.18632/aging.103632
PubMed: 32855361
PubMed Central: PMC7485721

Links to Exploration step

pubmed:32855361

Le document en format XML

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<term>Coronavirus Infections (blood)</term>
<term>Coronavirus Infections (mortality)</term>
<term>Coronavirus Infections (physiopathology)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Female (MeSH)</term>
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<term>Liver Diseases (diagnosis)</term>
<term>Liver Diseases (epidemiology)</term>
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<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Mortality (MeSH)</term>
<term>Neutrophils (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (blood)</term>
<term>Pneumonia, Viral (mortality)</term>
<term>Pneumonia, Viral (physiopathology)</term>
<term>Pneumonia, Viral (therapy)</term>
<term>Prognosis (MeSH)</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Previous work has described acute liver injury (ALI) in coronavirus disease 2019 (COVID-19) pneumonia patients, However, there is limited analyses available investigating chronic liver disease (CLD) in COVID-19 patients. This study aimed to investigate clinical characteristics and outcomes of CLD confirmed in COVID-19 patients.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A total of 104 cases (each group containing 52 patients) were analyzed in this study. The CLD group showed an average of 14 (10.0~21.2) length of stay (LOS) days, compared to the group without CLD that only showed an average of 12.5 (10~16) LOS days (Relative Risk [RR] = 1.34, 95% CI (1.22~1.48), P<0.001; Adjusted Relative Risk was 1.24 (95% CI: 1.12~1.39)). The CLD group contained a higher mortality rate and slight liver injury. Furthermore, COX regression model analyses suggested that the neutrophil-to-lymphocyte ratio (NLR) was an independent predictor of mortality risk (P < 0.001) in the CLD group. Additionally, a high NLR significantly correlated with a shorter overall survival (P <0.001).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>COVID-19 patients also diagnosed with CLD suffered longer LOS, slight liver injuries and a higher mortality when compared to COVID-19 patients without CLD. The NLR was an independent risk factor for in-hospital deaths. Increased expression of NLR was an indicator of poor prognosis in COVID-19 patients with CLD. Thus, COVID-19 patients diagnosed with CLD and who show a higher NLR need additional care.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>A retrospective cohort study was performed at the Wuhan Jin Yin-tan Hospital from February 2, 2020 to April 2, 2020. COVID-19 patients diagnosed with CLD or not diagnosed with CLD were enrolled in this study. The clinical characteristics and outcomes of these patients were compared.</p>
</div>
</front>
</TEI>
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<ArticleTitle>Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND">Previous work has described acute liver injury (ALI) in coronavirus disease 2019 (COVID-19) pneumonia patients, However, there is limited analyses available investigating chronic liver disease (CLD) in COVID-19 patients. This study aimed to investigate clinical characteristics and outcomes of CLD confirmed in COVID-19 patients.</AbstractText>
<AbstractText Label="RESULTS">A total of 104 cases (each group containing 52 patients) were analyzed in this study. The CLD group showed an average of 14 (10.0~21.2) length of stay (LOS) days, compared to the group without CLD that only showed an average of 12.5 (10~16) LOS days (Relative Risk [RR] = 1.34, 95% CI (1.22~1.48), P<0.001; Adjusted Relative Risk was 1.24 (95% CI: 1.12~1.39)). The CLD group contained a higher mortality rate and slight liver injury. Furthermore, COX regression model analyses suggested that the neutrophil-to-lymphocyte ratio (NLR) was an independent predictor of mortality risk (P < 0.001) in the CLD group. Additionally, a high NLR significantly correlated with a shorter overall survival (P <0.001).</AbstractText>
<AbstractText Label="CONCLUSIONS">COVID-19 patients also diagnosed with CLD suffered longer LOS, slight liver injuries and a higher mortality when compared to COVID-19 patients without CLD. The NLR was an independent risk factor for in-hospital deaths. Increased expression of NLR was an indicator of poor prognosis in COVID-19 patients with CLD. Thus, COVID-19 patients diagnosed with CLD and who show a higher NLR need additional care.</AbstractText>
<AbstractText Label="METHODS">A retrospective cohort study was performed at the Wuhan Jin Yin-tan Hospital from February 2, 2020 to April 2, 2020. COVID-19 patients diagnosed with CLD or not diagnosed with CLD were enrolled in this study. The clinical characteristics and outcomes of these patients were compared.</AbstractText>
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<ForeName>Chaowei</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.</Affiliation>
</AffiliationInfo>
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</AffiliationInfo>
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<ForeName>Jianwen</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Pulmonary Diseases and Tuberculosis, Jin Yin-Tan Hospital, Wuhan, China.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Lin</LastName>
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</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Zhirong</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Department of Surgical, The Fujian Pinghe County People's Hospital, Zhangzhou, China.</Affiliation>
</AffiliationInfo>
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<ReferenceList><Reference><Citation>J Med Virol. 2020 May 14;:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32406952</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2020 Jul;81(1):e6-e12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32283162</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA. 2020 Mar 17;323(11):1061-1069</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32031570</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Liver Int. 2020 May;40(5):998-1004</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32170806</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):762-768</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32161940</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Metab. 2016 Nov 8;24(5):657-671</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27641098</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2013 Oct 11;342(6155):1242454</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24115444</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2020 May 23;:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32445489</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Gastroenterol Hepatol. 2020 Apr 10;:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32282549</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Liver Int. 2020 Jun;40(6):1321-1326</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32239591</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Liver Int. 2020 Sep;40(9):2095-2103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32239796</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Gastroenterol Hepatol. 2020 Jun;5(6):529-530</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32203680</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Intensive Care Med. 2020 Jun;46(6):1294-1297</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32253449</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Transl Med. 2020 May 20;18(1):206</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32434518</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Sep 12;71(6):1393-1399</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32271369</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Feb 15;395(10223):497-506</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31986264</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):756-761</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32161968</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chest. 2020 Jul;158(1):97-105</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32304772</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Respir Med. 2020 May;8(5):475-481</Citation>
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</ArticleIdList>
</Reference>
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Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China.

Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China.

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