[Learning with COVID-19: what about anticoagulation?]
Identifieur interne : 000422 ( Main/Corpus ); précédent : 000421; suivant : 000423[Learning with COVID-19: what about anticoagulation?]
Auteurs : E. Álvarez-Rodríguez ; R. González González ; R. Torres-Gárate ; P. L Pez-Riquelme ; I. González Martil ; V. Abad Cu AdoSource :
- Anales del sistema sanitario de Navarra [ 1137-6627 ] ; 2020.
English descriptors
- KwdEn :
- Abdomen (MeSH), Acenocoumarol (adverse effects), Acenocoumarol (therapeutic use), Aged, 80 and over (MeSH), Anticoagulants (adverse effects), Anticoagulants (therapeutic use), Betacoronavirus (MeSH), Coronavirus Infections (complications), Female (MeSH), Hematoma (chemically induced), Hematoma (diagnosis), Heparin, Low-Molecular-Weight (adverse effects), Heparin, Low-Molecular-Weight (therapeutic use), Humans (MeSH), Pandemics (MeSH), Pneumonia, Viral (complications), Rivaroxaban (adverse effects), Rivaroxaban (therapeutic use), Venous Thromboembolism (drug therapy), Venous Thromboembolism (prevention & control), Venous Thromboembolism (virology).
- MESH :
- chemical , adverse effects : Acenocoumarol, Anticoagulants, Heparin, Low-Molecular-Weight, Rivaroxaban.
- chemical , therapeutic use : Acenocoumarol, Anticoagulants, Heparin, Low-Molecular-Weight, Rivaroxaban.
- chemically induced : Hematoma.
- complications : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Hematoma.
- drug therapy : Venous Thromboembolism.
- prevention & control : Venous Thromboembolism.
- virology : Venous Thromboembolism.
- Abdomen, Aged, 80 and over, Betacoronavirus, Female, Humans, Pandemics.
Abstract
Infection caused by SARS-CoV-2 (COVID-19) is associated with an increased risk of thromboembolic disease. So-me authors recommend anticoagulation at therapeutic doses for, at least, the most severely ill patients; this practice is not free of risks, which is why only thromboembolic prophylaxis is recommended by other consensuses. In the case of previously anticoagulated patients, changing the oral anticoagulant for a low molecular weight heparin (LMWH) is generally recommended. We present the cases of two patients admitted due to COVID-19, without serious clinical data, in whom anticoagulation (acenocoumarol and rivaroxaban, respectively) was replaced by LMWH at therapeutic doses, both presenting abdominal bleeding. This type of bleeding is an infrequent complication in anticoagulated patients, but the concurrence of two cases in a short period of time in the context of the COVID-19 pandemic leads us to consider that there is not yet any clear evidence on therapeutic anticoagulation in SARS-CoV-2 infection.
DOI: 10.23938/ASSN.0884
PubMed: 32865189
Links to Exploration step
pubmed:32865189Le document en format XML
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<author><name sortKey="Alvarez Rodriguez, E" sort="Alvarez Rodriguez, E" uniqKey="Alvarez Rodriguez E" first="E" last="Álvarez-Rodríguez">E. Álvarez-Rodríguez</name>
<affiliation><nlm:affiliation>Servicio de Urgencias. Hospital Universitario Severo Ochoa. Leganés, Madrid.. diabetes@portalsemes.org.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Gonzalez Gonzalez, R" sort="Gonzalez Gonzalez, R" uniqKey="Gonzalez Gonzalez R" first="R" last="González González">R. González González</name>
</author>
<author><name sortKey="Torres Garate, R" sort="Torres Garate, R" uniqKey="Torres Garate R" first="R" last="Torres-Gárate">R. Torres-Gárate</name>
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<author><name sortKey="L Pez Riquelme, P" sort="L Pez Riquelme, P" uniqKey="L Pez Riquelme P" first="P" last="L Pez-Riquelme">P. L Pez-Riquelme</name>
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<author><name sortKey="Gonzalez Martil, I" sort="Gonzalez Martil, I" uniqKey="Gonzalez Martil I" first="I" last="González Martil">I. González Martil</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Learning with COVID-19: what about anticoagulation?]</title>
<author><name sortKey="Alvarez Rodriguez, E" sort="Alvarez Rodriguez, E" uniqKey="Alvarez Rodriguez E" first="E" last="Álvarez-Rodríguez">E. Álvarez-Rodríguez</name>
<affiliation><nlm:affiliation>Servicio de Urgencias. Hospital Universitario Severo Ochoa. Leganés, Madrid.. diabetes@portalsemes.org.</nlm:affiliation>
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<series><title level="j">Anales del sistema sanitario de Navarra</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abdomen (MeSH)</term>
<term>Acenocoumarol (adverse effects)</term>
<term>Acenocoumarol (therapeutic use)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Anticoagulants (adverse effects)</term>
<term>Anticoagulants (therapeutic use)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Female (MeSH)</term>
<term>Hematoma (chemically induced)</term>
<term>Hematoma (diagnosis)</term>
<term>Heparin, Low-Molecular-Weight (adverse effects)</term>
<term>Heparin, Low-Molecular-Weight (therapeutic use)</term>
<term>Humans (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Rivaroxaban (adverse effects)</term>
<term>Rivaroxaban (therapeutic use)</term>
<term>Venous Thromboembolism (drug therapy)</term>
<term>Venous Thromboembolism (prevention & control)</term>
<term>Venous Thromboembolism (virology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Acenocoumarol</term>
<term>Anticoagulants</term>
<term>Heparin, Low-Molecular-Weight</term>
<term>Rivaroxaban</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Acenocoumarol</term>
<term>Anticoagulants</term>
<term>Heparin, Low-Molecular-Weight</term>
<term>Rivaroxaban</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Hematoma</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hematoma</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Venous Thromboembolism</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Venous Thromboembolism</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Venous Thromboembolism</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Abdomen</term>
<term>Aged, 80 and over</term>
<term>Betacoronavirus</term>
<term>Female</term>
<term>Humans</term>
<term>Pandemics</term>
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<front><div type="abstract" xml:lang="en">Infection caused by SARS-CoV-2 (COVID-19) is associated with an increased risk of thromboembolic disease. So-me authors recommend anticoagulation at therapeutic doses for, at least, the most severely ill patients; this practice is not free of risks, which is why only thromboembolic prophylaxis is recommended by other consensuses. In the case of previously anticoagulated patients, changing the oral anticoagulant for a low molecular weight heparin (LMWH) is generally recommended. We present the cases of two patients admitted due to COVID-19, without serious clinical data, in whom anticoagulation (acenocoumarol and rivaroxaban, respectively) was replaced by LMWH at therapeutic doses, both presenting abdominal bleeding. This type of bleeding is an infrequent complication in anticoagulated patients, but the concurrence of two cases in a short period of time in the context of the COVID-19 pandemic leads us to consider that there is not yet any clear evidence on therapeutic anticoagulation in SARS-CoV-2 infection.</div>
</front>
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<Abstract><AbstractText>Infection caused by SARS-CoV-2 (COVID-19) is associated with an increased risk of thromboembolic disease. So-me authors recommend anticoagulation at therapeutic doses for, at least, the most severely ill patients; this practice is not free of risks, which is why only thromboembolic prophylaxis is recommended by other consensuses. In the case of previously anticoagulated patients, changing the oral anticoagulant for a low molecular weight heparin (LMWH) is generally recommended. We present the cases of two patients admitted due to COVID-19, without serious clinical data, in whom anticoagulation (acenocoumarol and rivaroxaban, respectively) was replaced by LMWH at therapeutic doses, both presenting abdominal bleeding. This type of bleeding is an infrequent complication in anticoagulated patients, but the concurrence of two cases in a short period of time in the context of the COVID-19 pandemic leads us to consider that there is not yet any clear evidence on therapeutic anticoagulation in SARS-CoV-2 infection.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Álvarez-Rodríguez</LastName>
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