Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.
Identifieur interne : 000408 ( Main/Corpus ); précédent : 000407; suivant : 000409Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.
Auteurs : Sayan Manna ; Samuel Z. Maron ; Mario A. Cedillo ; Nicholas Voutsinas ; Danielle Toussie ; Mark Finkelstein ; Sharon Steinberger ; Michael Chung ; Adam Bernheim ; Corey Eber ; Yogesh Sean Gupta ; Jose Concepcion ; Richard Libes ; Adam JacobiSource :
- Clinical imaging [ 1873-4499 ] ; 2020.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (MeSH), Comorbidity (MeSH), Coronavirus Infections (complications), Coronavirus Infections (virology), Female (MeSH), Fibrin Fibrinogen Degradation Products (metabolism), Hospitalization (MeSH), Humans (MeSH), Male (MeSH), Mediastinal Emphysema (epidemiology), Mediastinal Emphysema (etiology), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (complications), Pneumonia, Viral (virology), Pneumothorax (epidemiology), Pneumothorax (etiology), Respiration, Artificial (adverse effects), Subcutaneous Emphysema (epidemiology), Subcutaneous Emphysema (etiology), Tomography, X-Ray Computed (methods).
- MESH :
- chemical , metabolism : Fibrin Fibrinogen Degradation Products.
- adverse effects : Respiration, Artificial.
- complications : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Mediastinal Emphysema, Pneumothorax, Subcutaneous Emphysema.
- etiology : Mediastinal Emphysema, Pneumothorax, Subcutaneous Emphysema.
- methods : Tomography, X-Ray Computed.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adult, Aged, Aged, 80 and over, Betacoronavirus, Comorbidity, Female, Hospitalization, Humans, Male, Middle Aged, Pandemics.
Abstract
PURPOSE
We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation.
MATERIALS AND METHODS
A total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected. Chest radiography (CXR) and computed tomography (CT) were analyzed for SE, SPM, and pneumothorax by a board-certified cardiothoracic-fellowship trained radiologist.
RESULTS
Eleven non-intubated patients developed SE, 36% (4/11) of whom had SE on their initial CXR. Concomitant SPM was apparent in 91% (10/11) of patients, and 45% (5/11) also developed pneumothorax. Patients developed SE on average 13.3 days (SD: 6.3) following symptom onset. No patients reported a history of smoking. The most common comorbidities included hypertension (6/11), diabetes mellitus (5/11), asthma (3/11), dyslipidemia (3/11), and renal disease (2/11). Four (36%) patients expired during hospitalization.
CONCLUSION
SE and SPM were observed in a cohort of 11 non-intubated COVID-19 patients without any known cause or history of invasive ventilation. Further investigation is required to elucidate the underlying mechanism in this patient population.
DOI: 10.1016/j.clinimag.2020.08.013
PubMed: 32871424
PubMed Central: PMC7448957
Links to Exploration step
pubmed:32871424Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.</title><author><name sortKey="Manna, Sayan" sort="Manna, Sayan" uniqKey="Manna S" first="Sayan" last="Manna">Sayan Manna</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA. Electronic address: sayan.manna@icahn.mssm.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Maron, Samuel Z" sort="Maron, Samuel Z" uniqKey="Maron S" first="Samuel Z" last="Maron">Samuel Z. Maron</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cedillo, Mario A" sort="Cedillo, Mario A" uniqKey="Cedillo M" first="Mario A" last="Cedillo">Mario A. Cedillo</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Voutsinas, Nicholas" sort="Voutsinas, Nicholas" uniqKey="Voutsinas N" first="Nicholas" last="Voutsinas">Nicholas Voutsinas</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Toussie, Danielle" sort="Toussie, Danielle" uniqKey="Toussie D" first="Danielle" last="Toussie">Danielle Toussie</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Finkelstein, Mark" sort="Finkelstein, Mark" uniqKey="Finkelstein M" first="Mark" last="Finkelstein">Mark Finkelstein</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Steinberger, Sharon" sort="Steinberger, Sharon" uniqKey="Steinberger S" first="Sharon" last="Steinberger">Sharon Steinberger</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Michael" sort="Chung, Michael" uniqKey="Chung M" first="Michael" last="Chung">Michael Chung</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Bernheim, Adam" sort="Bernheim, Adam" uniqKey="Bernheim A" first="Adam" last="Bernheim">Adam Bernheim</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eber, Corey" sort="Eber, Corey" uniqKey="Eber C" first="Corey" last="Eber">Corey Eber</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gupta, Yogesh Sean" sort="Gupta, Yogesh Sean" uniqKey="Gupta Y" first="Yogesh Sean" last="Gupta">Yogesh Sean Gupta</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Concepcion, Jose" sort="Concepcion, Jose" uniqKey="Concepcion J" first="Jose" last="Concepcion">Jose Concepcion</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Libes, Richard" sort="Libes, Richard" uniqKey="Libes R" first="Richard" last="Libes">Richard Libes</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobi, Adam" sort="Jacobi, Adam" uniqKey="Jacobi A" first="Adam" last="Jacobi">Adam Jacobi</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32871424</idno><idno type="pmid">32871424</idno><idno type="doi">10.1016/j.clinimag.2020.08.013</idno><idno type="pmc">PMC7448957</idno><idno type="wicri:Area/Main/Corpus">000408</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000408</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.</title><author><name sortKey="Manna, Sayan" sort="Manna, Sayan" uniqKey="Manna S" first="Sayan" last="Manna">Sayan Manna</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA. Electronic address: sayan.manna@icahn.mssm.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Maron, Samuel Z" sort="Maron, Samuel Z" uniqKey="Maron S" first="Samuel Z" last="Maron">Samuel Z. Maron</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cedillo, Mario A" sort="Cedillo, Mario A" uniqKey="Cedillo M" first="Mario A" last="Cedillo">Mario A. Cedillo</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Voutsinas, Nicholas" sort="Voutsinas, Nicholas" uniqKey="Voutsinas N" first="Nicholas" last="Voutsinas">Nicholas Voutsinas</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Toussie, Danielle" sort="Toussie, Danielle" uniqKey="Toussie D" first="Danielle" last="Toussie">Danielle Toussie</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Finkelstein, Mark" sort="Finkelstein, Mark" uniqKey="Finkelstein M" first="Mark" last="Finkelstein">Mark Finkelstein</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Steinberger, Sharon" sort="Steinberger, Sharon" uniqKey="Steinberger S" first="Sharon" last="Steinberger">Sharon Steinberger</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Michael" sort="Chung, Michael" uniqKey="Chung M" first="Michael" last="Chung">Michael Chung</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Bernheim, Adam" sort="Bernheim, Adam" uniqKey="Bernheim A" first="Adam" last="Bernheim">Adam Bernheim</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eber, Corey" sort="Eber, Corey" uniqKey="Eber C" first="Corey" last="Eber">Corey Eber</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gupta, Yogesh Sean" sort="Gupta, Yogesh Sean" uniqKey="Gupta Y" first="Yogesh Sean" last="Gupta">Yogesh Sean Gupta</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Concepcion, Jose" sort="Concepcion, Jose" uniqKey="Concepcion J" first="Jose" last="Concepcion">Jose Concepcion</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Libes, Richard" sort="Libes, Richard" uniqKey="Libes R" first="Richard" last="Libes">Richard Libes</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobi, Adam" sort="Jacobi, Adam" uniqKey="Jacobi A" first="Adam" last="Jacobi">Adam Jacobi</name><affiliation><nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Clinical imaging</title><idno type="eISSN">1873-4499</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Comorbidity (MeSH)</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (virology)</term><term>Female (MeSH)</term><term>Fibrin Fibrinogen Degradation Products (metabolism)</term><term>Hospitalization (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Mediastinal Emphysema (epidemiology)</term><term>Mediastinal Emphysema (etiology)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (virology)</term><term>Pneumothorax (epidemiology)</term><term>Pneumothorax (etiology)</term><term>Respiration, Artificial (adverse effects)</term><term>Subcutaneous Emphysema (epidemiology)</term><term>Subcutaneous Emphysema (etiology)</term><term>Tomography, X-Ray Computed (methods)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Fibrin Fibrinogen Degradation Products</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Respiration, Artificial</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Mediastinal Emphysema</term><term>Pneumothorax</term><term>Subcutaneous Emphysema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Mediastinal Emphysema</term><term>Pneumothorax</term><term>Subcutaneous Emphysema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Betacoronavirus</term><term>Comorbidity</term><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>PURPOSE</b></p><p>We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation.</p></div><div type="abstract" xml:lang="en"><p><b>MATERIALS AND METHODS</b></p><p>A total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected. Chest radiography (CXR) and computed tomography (CT) were analyzed for SE, SPM, and pneumothorax by a board-certified cardiothoracic-fellowship trained radiologist.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Eleven non-intubated patients developed SE, 36% (4/11) of whom had SE on their initial CXR. Concomitant SPM was apparent in 91% (10/11) of patients, and 45% (5/11) also developed pneumothorax. Patients developed SE on average 13.3 days (SD: 6.3) following symptom onset. No patients reported a history of smoking. The most common comorbidities included hypertension (6/11), diabetes mellitus (5/11), asthma (3/11), dyslipidemia (3/11), and renal disease (2/11). Four (36%) patients expired during hospitalization.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>SE and SPM were observed in a cohort of 11 non-intubated COVID-19 patients without any known cause or history of invasive ventilation. Further investigation is required to elucidate the underlying mechanism in this patient population.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32871424</PMID><DateCompleted><Year>2020</Year><Month>09</Month><Day>21</Day></DateCompleted><DateRevised><Year>2020</Year><Month>09</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-4499</ISSN><JournalIssue CitedMedium="Internet"><Volume>67</Volume><PubDate><Year>2020</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Clinical imaging</Title><ISOAbbreviation>Clin Imaging</ISOAbbreviation></Journal><ArticleTitle>Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.</ArticleTitle><Pagination><MedlinePgn>207-213</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0899-7071(20)30318-1</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.clinimag.2020.08.013</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">A total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected. Chest radiography (CXR) and computed tomography (CT) were analyzed for SE, SPM, and pneumothorax by a board-certified cardiothoracic-fellowship trained radiologist.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Eleven non-intubated patients developed SE, 36% (4/11) of whom had SE on their initial CXR. Concomitant SPM was apparent in 91% (10/11) of patients, and 45% (5/11) also developed pneumothorax. Patients developed SE on average 13.3 days (SD: 6.3) following symptom onset. No patients reported a history of smoking. The most common comorbidities included hypertension (6/11), diabetes mellitus (5/11), asthma (3/11), dyslipidemia (3/11), and renal disease (2/11). Four (36%) patients expired during hospitalization.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">SE and SPM were observed in a cohort of 11 non-intubated COVID-19 patients without any known cause or history of invasive ventilation. Further investigation is required to elucidate the underlying mechanism in this patient population.</AbstractText><CopyrightInformation>Copyright © 2020 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Manna</LastName><ForeName>Sayan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA. Electronic address: sayan.manna@icahn.mssm.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maron</LastName><ForeName>Samuel Z</ForeName><Initials>SZ</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cedillo</LastName><ForeName>Mario A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Voutsinas</LastName><ForeName>Nicholas</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toussie</LastName><ForeName>Danielle</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Finkelstein</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steinberger</LastName><ForeName>Sharon</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chung</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bernheim</LastName><ForeName>Adam</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eber</LastName><ForeName>Corey</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gupta</LastName><ForeName>Yogesh Sean</ForeName><Initials>YS</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Concepcion</LastName><ForeName>Jose</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Libes</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobi</LastName><ForeName>Adam</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY 10029, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Imaging</MedlineTA><NlmUniqueID>8911831</NlmUniqueID><ISSNLinking>0899-7071</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005338">Fibrin Fibrinogen Degradation Products</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C036309">fibrin fragment D</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005338" MajorTopicYN="N">Fibrin Fibrinogen Degradation Products</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008478" MajorTopicYN="N">Mediastinal Emphysema</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011030" MajorTopicYN="N">Pneumothorax</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012121" MajorTopicYN="N">Respiration, Artificial</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013352" MajorTopicYN="N">Subcutaneous Emphysema</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Pneumomediastinum</Keyword><Keyword MajorTopicYN="N">Subcutaneous emphysema</Keyword></KeywordList><CoiStatement>Declaration of competing interest The authors have no conflicts of interests to disclose. No financial or material support was received for this work.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>06</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>07</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>08</Month><Day>18</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>9</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>9</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>9</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32871424</ArticleId><ArticleId IdType="pii">S0899-7071(20)30318-1</ArticleId><ArticleId IdType="doi">10.1016/j.clinimag.2020.08.013</ArticleId><ArticleId IdType="pmc">PMC7448957</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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