Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy.
Identifieur interne : 001343 ( Main/Exploration ); précédent : 001342; suivant : 001344Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy.
Auteurs : Giuseppe Di Lorenzo [Oman] ; Luciana Buonerba [Italie] ; Concetta Ingenito [Italie] ; Felice Crocetto [Italie] ; Carlo Buonerba [Italie] ; Annamaria Libroia [Italie] ; Antonella Sciarra [Italie] ; Gianluca Ragone [Italie] ; Roberto Sanseverino [Italie] ; Simona Iaccarino [Italie] ; Giorgio Napodano [Italie] ; Ciro Imbimbo [Italie] ; Emilio Leo [Italie] ; Zisis Kozlakidis [France] ; Sabino De Placido [Italie]Source :
- Oncology [ 1423-0232 ] ; 2020.
Abstract
BACKGROUND
To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown.
METHODS
We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, at the Tortora Hospital, Pagani, Italy.
RESULTS
Among 72 patients, 48 and 24 were hormone-sensitive (HS) and castration-resistant prostate cancer (CRPC), respectively; 0 HS and 2 (8.3%) CRPC (p < 0.05) were positive for COVID-19. Both patients were receiving LHRH agonist therapy, and 1 patient was receiving enzalutamide. Urgent intensive care unit admission was required due to clinical worsening. Blood tests showed severe lymphopenia, anemia, and an increase in platelets. Retroviral therapy, antibiotics, heparin, and chloroquine were prescribed at the beginning. One patient also received tocilizumab as a salvage treatment. After 3 weeks of hospitalization, the patients were discharged from the hospital. Both patients suffered from an aggressive COVID-19 course due to concomitant comorbidities.
CONCLUSIONS
Investigating whether hormonal therapy, especially in advanced disease, acts as a protective factor or a risk factor during COVID-19 could be useful.
DOI: 10.1159/000509434
PubMed: 32570240
PubMed Central: PMC7360489
Affiliations:
Links toward previous steps (curation, corpus...)
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xml:lang="fr">Italie</country><wicri:regionArea>Urology Division, Umberto I Hospital, Nocera Inferiore</wicri:regionArea><wicri:noRegion>Nocera Inferiore</wicri:noRegion></affiliation></author><author><name sortKey="Iaccarino, Simona" sort="Iaccarino, Simona" uniqKey="Iaccarino S" first="Simona" last="Iaccarino">Simona Iaccarino</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Napodano, Giorgio" sort="Napodano, Giorgio" uniqKey="Napodano G" first="Giorgio" last="Napodano">Giorgio Napodano</name><affiliation wicri:level="1"><nlm:affiliation>Urology Division, Umberto I Hospital, Nocera Inferiore, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Urology Division, Umberto I Hospital, Nocera Inferiore</wicri:regionArea><wicri:noRegion>Nocera Inferiore</wicri:noRegion></affiliation></author><author><name sortKey="Imbimbo, Ciro" sort="Imbimbo, Ciro" uniqKey="Imbimbo C" first="Ciro" last="Imbimbo">Ciro Imbimbo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Leo, Emilio" sort="Leo, Emilio" uniqKey="Leo E" first="Emilio" last="Leo">Emilio Leo</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Kozlakidis, Zisis" sort="Kozlakidis, Zisis" uniqKey="Kozlakidis Z" first="Zisis" last="Kozlakidis">Zisis Kozlakidis</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer, World Health Organization, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, World Health Organization, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="De Placido, Sabino" sort="De Placido, Sabino" uniqKey="De Placido S" first="Sabino" last="De Placido">Sabino De Placido</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32570240</idno><idno type="pmid">32570240</idno><idno type="doi">10.1159/000509434</idno><idno type="pmc">PMC7360489</idno><idno type="wicri:Area/Main/Corpus">000C57</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000C57</idno><idno type="wicri:Area/Main/Curation">000C57</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000C57</idno><idno type="wicri:Area/Main/Exploration">000C57</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy.</title><author><name sortKey="Di Lorenzo, Giuseppe" sort="Di Lorenzo, Giuseppe" uniqKey="Di Lorenzo G" first="Giuseppe" last="Di Lorenzo">Giuseppe Di Lorenzo</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy, direttoreuocpagani@gmail.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy</wicri:regionArea><wicri:noRegion>Italy</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy, direttoreuocpagani@gmail.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy</wicri:regionArea><wicri:noRegion>Italy</wicri:noRegion></affiliation></author><author><name sortKey="Buonerba, Luciana" sort="Buonerba, Luciana" uniqKey="Buonerba L" first="Luciana" last="Buonerba">Luciana Buonerba</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Ingenito, Concetta" sort="Ingenito, Concetta" uniqKey="Ingenito C" first="Concetta" last="Ingenito">Concetta Ingenito</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Crocetto, Felice" sort="Crocetto, Felice" uniqKey="Crocetto F" first="Felice" last="Crocetto">Felice Crocetto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Buonerba, Carlo" sort="Buonerba, Carlo" uniqKey="Buonerba C" first="Carlo" last="Buonerba">Carlo Buonerba</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Libroia, Annamaria" sort="Libroia, Annamaria" uniqKey="Libroia A" first="Annamaria" last="Libroia">Annamaria Libroia</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Sciarra, Antonella" sort="Sciarra, Antonella" uniqKey="Sciarra A" first="Antonella" last="Sciarra">Antonella Sciarra</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Ragone, Gianluca" sort="Ragone, Gianluca" uniqKey="Ragone G" first="Gianluca" last="Ragone">Gianluca Ragone</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Sanseverino, Roberto" sort="Sanseverino, Roberto" uniqKey="Sanseverino R" first="Roberto" last="Sanseverino">Roberto Sanseverino</name><affiliation wicri:level="1"><nlm:affiliation>Urology Division, Umberto I Hospital, Nocera Inferiore, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Urology Division, Umberto I Hospital, Nocera Inferiore</wicri:regionArea><wicri:noRegion>Nocera Inferiore</wicri:noRegion></affiliation></author><author><name sortKey="Iaccarino, Simona" sort="Iaccarino, Simona" uniqKey="Iaccarino S" first="Simona" last="Iaccarino">Simona Iaccarino</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Napodano, Giorgio" sort="Napodano, Giorgio" uniqKey="Napodano G" first="Giorgio" last="Napodano">Giorgio Napodano</name><affiliation wicri:level="1"><nlm:affiliation>Urology Division, Umberto I Hospital, Nocera Inferiore, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Urology Division, Umberto I Hospital, Nocera Inferiore</wicri:regionArea><wicri:noRegion>Nocera Inferiore</wicri:noRegion></affiliation></author><author><name sortKey="Imbimbo, Ciro" sort="Imbimbo, Ciro" uniqKey="Imbimbo C" first="Ciro" last="Imbimbo">Ciro Imbimbo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Leo, Emilio" sort="Leo, Emilio" uniqKey="Leo E" first="Emilio" last="Leo">Emilio Leo</name><affiliation wicri:level="1"><nlm:affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani</wicri:regionArea><wicri:noRegion>Pagani</wicri:noRegion></affiliation></author><author><name sortKey="Kozlakidis, Zisis" sort="Kozlakidis, Zisis" uniqKey="Kozlakidis Z" first="Zisis" last="Kozlakidis">Zisis Kozlakidis</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer, World Health Organization, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, World Health Organization, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="De Placido, Sabino" sort="De Placido, Sabino" uniqKey="De Placido S" first="Sabino" last="De Placido">Sabino De Placido</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author></analytic><series><title level="j">Oncology</title><idno type="eISSN">1423-0232</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, at the Tortora Hospital, Pagani, Italy.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Among 72 patients, 48 and 24 were hormone-sensitive (HS) and castration-resistant prostate cancer (CRPC), respectively; 0 HS and 2 (8.3%) CRPC (p < 0.05) were positive for COVID-19. Both patients were receiving LHRH agonist therapy, and 1 patient was receiving enzalutamide. Urgent intensive care unit admission was required due to clinical worsening. Blood tests showed severe lymphopenia, anemia, and an increase in platelets. Retroviral therapy, antibiotics, heparin, and chloroquine were prescribed at the beginning. One patient also received tocilizumab as a salvage treatment. After 3 weeks of hospitalization, the patients were discharged from the hospital. Both patients suffered from an aggressive COVID-19 course due to concomitant comorbidities.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Investigating whether hormonal therapy, especially in advanced disease, acts as a protective factor or a risk factor during COVID-19 could be useful.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32570240</PMID><DateRevised><Year>2020</Year><Month>07</Month><Day>17</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1423-0232</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Jun</Month><Day>22</Day></PubDate></JournalIssue><Title>Oncology</Title><ISOAbbreviation>Oncology</ISOAbbreviation></Journal><ArticleTitle>Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy.</ArticleTitle><Pagination><MedlinePgn>1-5</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1159/000509434</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, at the Tortora Hospital, Pagani, Italy.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Among 72 patients, 48 and 24 were hormone-sensitive (HS) and castration-resistant prostate cancer (CRPC), respectively; 0 HS and 2 (8.3%) CRPC (p < 0.05) were positive for COVID-19. Both patients were receiving LHRH agonist therapy, and 1 patient was receiving enzalutamide. Urgent intensive care unit admission was required due to clinical worsening. Blood tests showed severe lymphopenia, anemia, and an increase in platelets. Retroviral therapy, antibiotics, heparin, and chloroquine were prescribed at the beginning. One patient also received tocilizumab as a salvage treatment. After 3 weeks of hospitalization, the patients were discharged from the hospital. Both patients suffered from an aggressive COVID-19 course due to concomitant comorbidities.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Investigating whether hormonal therapy, especially in advanced disease, acts as a protective factor or a risk factor during COVID-19 could be useful.</AbstractText><CopyrightInformation>© 2020 S. Karger AG, Basel.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Di Lorenzo</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy, direttoreuocpagani@gmail.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy, direttoreuocpagani@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buonerba</LastName><ForeName>Luciana</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ingenito</LastName><ForeName>Concetta</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Crocetto</LastName><ForeName>Felice</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buonerba</LastName><ForeName>Carlo</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Libroia</LastName><ForeName>Annamaria</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sciarra</LastName><ForeName>Antonella</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ragone</LastName><ForeName>Gianluca</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanseverino</LastName><ForeName>Roberto</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Urology Division, Umberto I Hospital, Nocera Inferiore, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iaccarino</LastName><ForeName>Simona</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Napodano</LastName><ForeName>Giorgio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Urology Division, Umberto I Hospital, Nocera Inferiore, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Imbimbo</LastName><ForeName>Ciro</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leo</LastName><ForeName>Emilio</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kozlakidis</LastName><ForeName>Zisis</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer, World Health Organization, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Placido</LastName><ForeName>Sabino</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016433">News</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>06</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Oncology</MedlineTA><NlmUniqueID>0135054</NlmUniqueID><ISSNLinking>0030-2414</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Comorbidities</Keyword><Keyword MajorTopicYN="N">Coronavirus disease SARS-CoV-2</Keyword><Keyword MajorTopicYN="N">Drug interaction</Keyword><Keyword MajorTopicYN="N">Hormonal therapy</Keyword><Keyword MajorTopicYN="N">Prostate cancer</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>06</Month><Day>10</Day></PubMedPubDate><PubMedPubDate 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