Serveur d'exploration sur la COVID en France

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Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands.

Identifieur interne : 001132 ( Main/Exploration ); précédent : 001131; suivant : 001133

Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands.

Auteurs : Matthijs Oudkerk [Pays-Bas] ; Harry R. Büller [Pays-Bas] ; Dirkjan Kuijpers [Pays-Bas] ; Nick Van Es [Pays-Bas] ; Sytse F. Oudkerk [Pays-Bas] ; Theresa Mcloud [Pays-Bas] ; Diederik Gommers [Pays-Bas] ; Jaap Van Dissel [Pays-Bas] ; Hugo Ten Cate [Pays-Bas] ; Edwin J R. Van Beek [Pays-Bas]

Source :

RBID : pubmed:32324101

Abstract

A potential link between mortality, d-dimer values, and a prothrombotic syndrome has been reported in patients with coronavirus disease 2019 (COVID-19) infection. The National Institute for Public Health of the Netherlands asked a group of radiology and vascular medicine experts to provide guidance for the imaging work-up and treatment of these important complications. This report summarizes evidence for thromboembolic disease, potential diagnostic and preventive actions, and recommendations for prophylaxis and treatment of patients with COVID-19 infection.

DOI: 10.1148/radiol.2020201629
PubMed: 32324101
PubMed Central: PMC7233406


Affiliations:


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Le document en format XML

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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<name sortKey="Van Es, Nick" sort="Van Es, Nick" uniqKey="Van Es N" first="Nick" last="Van Es">Nick Van Es</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<name sortKey="Mcloud, Theresa" sort="Mcloud, Theresa" uniqKey="Mcloud T" first="Theresa" last="Mcloud">Theresa Mcloud</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<name sortKey="Gommers, Diederik" sort="Gommers, Diederik" uniqKey="Gommers D" first="Diederik" last="Gommers">Diederik Gommers</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
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<name sortKey="Van Dissel, Jaap" sort="Van Dissel, Jaap" uniqKey="Van Dissel J" first="Jaap" last="Van Dissel">Jaap Van Dissel</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
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<name sortKey="Ten Cate, Hugo" sort="Ten Cate, Hugo" uniqKey="Ten Cate H" first="Hugo" last="Ten Cate">Hugo Ten Cate</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
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<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
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<name sortKey="Van Beek, Edwin J R" sort="Van Beek, Edwin J R" uniqKey="Van Beek E" first="Edwin J R" last="Van Beek">Edwin J R. Van Beek</name>
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<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
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<title xml:lang="en">Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands.</title>
<author>
<name sortKey="Oudkerk, Matthijs" sort="Oudkerk, Matthijs" uniqKey="Oudkerk M" first="Matthijs" last="Oudkerk">Matthijs Oudkerk</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
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<name sortKey="Buller, Harry R" sort="Buller, Harry R" uniqKey="Buller H" first="Harry R" last="Büller">Harry R. Büller</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
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<name sortKey="Kuijpers, Dirkjan" sort="Kuijpers, Dirkjan" uniqKey="Kuijpers D" first="Dirkjan" last="Kuijpers">Dirkjan Kuijpers</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
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<name sortKey="Van Es, Nick" sort="Van Es, Nick" uniqKey="Van Es N" first="Nick" last="Van Es">Nick Van Es</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
</placeName>
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<author>
<name sortKey="Oudkerk, Sytse F" sort="Oudkerk, Sytse F" uniqKey="Oudkerk S" first="Sytse F" last="Oudkerk">Sytse F. Oudkerk</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
</placeName>
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<author>
<name sortKey="Mcloud, Theresa" sort="Mcloud, Theresa" uniqKey="Mcloud T" first="Theresa" last="Mcloud">Theresa Mcloud</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Gommers, Diederik" sort="Gommers, Diederik" uniqKey="Gommers D" first="Diederik" last="Gommers">Diederik Gommers</name>
<affiliation wicri:level="4">
<nlm:affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</nlm:affiliation>
<orgName type="university">Université de Groningue</orgName>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
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<div type="abstract" xml:lang="en">A potential link between mortality, d-dimer values, and a prothrombotic syndrome has been reported in patients with coronavirus disease 2019 (COVID-19) infection. The National Institute for Public Health of the Netherlands asked a group of radiology and vascular medicine experts to provide guidance for the imaging work-up and treatment of these important complications. This report summarizes evidence for thromboembolic disease, potential diagnostic and preventive actions, and recommendations for prophylaxis and treatment of patients with COVID-19 infection.</div>
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<AbstractText>A potential link between mortality, d-dimer values, and a prothrombotic syndrome has been reported in patients with coronavirus disease 2019 (COVID-19) infection. The National Institute for Public Health of the Netherlands asked a group of radiology and vascular medicine experts to provide guidance for the imaging work-up and treatment of these important complications. This report summarizes evidence for thromboembolic disease, potential diagnostic and preventive actions, and recommendations for prophylaxis and treatment of patients with COVID-19 infection.</AbstractText>
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<Affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</Affiliation>
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<Affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</Affiliation>
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<AffiliationInfo>
<Affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</Affiliation>
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<Affiliation>From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Institute for Diagnostic Accuracy, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.v.E.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.v.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.t.C.); and Edinburgh Imaging, CO.19, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland (E.J.R.v.B.).</Affiliation>
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