[Real-life data and Covid-19: The third avenue of reseach].
Identifieur interne : 000117 ( Main/Exploration ); précédent : 000116; suivant : 000118[Real-life data and Covid-19: The third avenue of reseach].
Auteurs : L. Boyer [France] ; P. Auquier [France] ; G. Fond [France]Source :
- L'Encephale [ 0013-7006 ] ; 2020.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Archives administratives hospitalières (statistiques et données numériques), Betacoronavirus (MeSH), Essais contrôlés randomisés comme sujet (statistiques et données numériques), France (épidémiologie), Humains (MeSH), Hydroxychloroquine (usage thérapeutique), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (épidémiologie), Logiciel (MeSH), Médecine factuelle (MeSH), Médicaments en essais cliniques (usage thérapeutique), Pandémies (MeSH), Plan de recherche (MeSH), Pneumopathie virale (traitement médicamenteux), Pneumopathie virale (épidémiologie), Repositionnement des médicaments (MeSH), Systèmes d'information hospitaliers (statistiques et données numériques), Études rétrospectives (MeSH).
- MESH :
- statistiques et données numériques : Archives administratives hospitalières, Essais contrôlés randomisés comme sujet, Systèmes d'information hospitaliers.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Antiviraux, Hydroxychloroquine, Médicaments en essais cliniques.
- épidémiologie : France, Infections à coronavirus, Pneumopathie virale.
- Betacoronavirus, Humains, Logiciel, Médecine factuelle, Pandémies, Plan de recherche, Repositionnement des médicaments, Études rétrospectives.
- Wicri :
- geographic : France.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), Betacoronavirus (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Drug Repositioning (MeSH), Drugs, Investigational (therapeutic use), Evidence-Based Medicine (MeSH), France (epidemiology), Hospital Information Systems (statistics & numerical data), Hospital Records (statistics & numerical data), Humans (MeSH), Hydroxychloroquine (therapeutic use), Pandemics (MeSH), Pneumonia, Viral (drug therapy), Pneumonia, Viral (epidemiology), Randomized Controlled Trials as Topic (statistics & numerical data), Research Design (MeSH), Retrospective Studies (MeSH), Software (MeSH).
- MESH :
- chemical , therapeutic use : Antiviral Agents, Drugs, Investigational, Hydroxychloroquine.
- geographic , epidemiology : France.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- statistics & numerical data : Hospital Information Systems, Hospital Records, Randomized Controlled Trials as Topic.
- Betacoronavirus, Drug Repositioning, Evidence-Based Medicine, Humans, Pandemics, Research Design, Retrospective Studies, Software.
Abstract
The analysis of real-life data from hospital information systems could make possible to decide on the efficacy and safety of Covid-19 treatments by avoiding the pitfalls of preliminary studies and randomized clinical trials. The different drugs tested in current clinical trials are already widely prescribed to patients by doctors in hospitals, and can therefore be immediately analysed according to validated methodological standards.
DOI: 10.1016/j.encep.2020.04.003
PubMed: 32362504
PubMed Central: PMC7174151
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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xml:lang="en">The analysis of real-life data from hospital information systems could make possible to decide on the efficacy and safety of Covid-19 treatments by avoiding the pitfalls of preliminary studies and randomized clinical trials. The different drugs tested in current clinical trials are already widely prescribed to patients by doctors in hospitals, and can therefore be immediately analysed according to validated methodological standards.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32362504</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>13</Day></DateCompleted><DateRevised><Year>2020</Year><Month>07</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0013-7006</ISSN><JournalIssue CitedMedium="Internet"><Volume>46</Volume><Issue>3S</Issue><PubDate><Year>2020</Year><Month>Jun</Month></PubDate></JournalIssue><Title>L'Encephale</Title><ISOAbbreviation>Encephale</ISOAbbreviation></Journal><ArticleTitle>[Real-life data and Covid-19: The third avenue of reseach].</ArticleTitle><Pagination><MedlinePgn>S114-S115</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0013-7006(20)30071-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.encep.2020.04.003</ELocationID><Abstract><AbstractText>The analysis of real-life data from hospital information systems could make possible to decide on the efficacy and safety of Covid-19 treatments by avoiding the pitfalls of preliminary studies and randomized clinical trials. The different drugs tested in current clinical trials are already widely prescribed to patients by doctors in hospitals, and can therefore be immediately analysed according to validated methodological standards.</AbstractText><CopyrightInformation>Copyright © 2020 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Boyer</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>EA 3279, Secteur Timone, centre d'études et de recherches sur les services de santé et qualité de vie (CEReSS), faculté de médecine, Aix-Marseille Université Marseille, 27, boulevard Jean-Moulin, 13005 Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Auquier</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>EA 3279, Secteur Timone, centre d'études et de recherches sur les services de santé et qualité de vie (CEReSS), faculté de médecine, Aix-Marseille Université Marseille, 27, boulevard Jean-Moulin, 13005 Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fond</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>EA 3279, Secteur Timone, centre d'études et de recherches sur les services de santé et qualité de vie (CEReSS), faculté de médecine, Aix-Marseille Université Marseille, 27, boulevard Jean-Moulin, 13005 Marseille, France. Electronic address: guillaume.fond@ap-hm.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>fre</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Données de vie réelle et Covid-19 : la troisième voie.</VernacularTitle><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Encephale</MedlineTA><NlmUniqueID>7505643</NlmUniqueID><ISSNLinking>0013-7006</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015507">Drugs, Investigational</NameOfSubstance></Chemical><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance 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UI="D058492" MajorTopicYN="N">Drug Repositioning</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015507" MajorTopicYN="N">Drugs, Investigational</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019317" MajorTopicYN="N">Evidence-Based Medicine</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006751" MajorTopicYN="N">Hospital Information Systems</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006753" MajorTopicYN="N">Hospital Records</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012107" MajorTopicYN="Y">Research Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective 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