Real-World Inpatient Use of Medications Repurposed for Coronavirus Disease 2019 in United States Hospitals, March-May 2020.
Identifieur interne : 000222 ( Main/Exploration ); précédent : 000221; suivant : 000223Real-World Inpatient Use of Medications Repurposed for Coronavirus Disease 2019 in United States Hospitals, March-May 2020.
Auteurs : Sameer S. Kadri [États-Unis] ; Cumhur Y. Demirkale [États-Unis] ; Junfeng Sun [États-Unis] ; Lindsay M. Busch [États-Unis] ; Jeffrey R. Strich [États-Unis] ; Ning Rosenthal [États-Unis] ; Sarah Warner [États-Unis]Source :
- Open forum infectious diseases [ 2328-8957 ] ; 2021.
Abstract
We report off-label use patterns for medications repurposed for coronavirus disease 2019 (COVID-19) at 318 US hospitals. Inpatient hydroxychloroquine use declined by 80%, whereas corticosteroids and tocilizumab were initiated 2 days earlier in May versus March 2020. Two thirds of ventilated COVID-19 patients were already receiving corticosteroids during March-May 2020, resembling pre-COVID use in mechanically ventilated influenza patients.
DOI: 10.1093/ofid/ofaa616
PubMed: 33556157
PubMed Central: PMC7798707
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We report off-label use patterns for medications repurposed for coronavirus disease 2019 (COVID-19) at 318 US hospitals. Inpatient hydroxychloroquine use declined by 80%, whereas corticosteroids and tocilizumab were initiated 2 days earlier in May versus March 2020. Two thirds of ventilated COVID-19 patients were already receiving corticosteroids during March-May 2020, resembling pre-COVID use in mechanically ventilated influenza patients.</div>
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