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Prophetic Medicine-Nigella Sativa (Black cumin seeds) - Potential herb for COVID-19?

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Prophetic Medicine-Nigella Sativa (Black cumin seeds) - Potential herb for COVID-19?

Auteurs : Naina Mohamed Pakkir Maideen [Émirats arabes unis]

Source :

Journal of pharmacopuncture [ 2093-6966 ] ; 2020.

RBID : pubmed:32685234

Abstract

Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Currently, the management of patients with COVID-19 depends mainly on repurposed drugs which include chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β and others. In this review, the potential of Nigella sativa (black cumin seeds) to treat the patients with COVID-19 analyzed, as it has shown to possess antiviral, antioxidant, anti-inflammatory, anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic and analgesic activities. PubMed, Google Scholar, Science Direct, Directory of open access journals (DOAJ) and reference lists were searched to identify articles associated with antiviral and other properties of N.sativa related to the signs and symptoms of COVID-19. Various randomized controlled trials, pilot studies, case reports and in vitro and in vivo studies confirmed that N.sativa has antiviral, antioxidant, anti-inflammatory, immunomodulatory, bronchodilatory, antihistaminic, antitussive activities related to causative oraganism and signs and symptoms of COVID-19. N. sativa could be used as an adjuvant therapy along with repurposed conventional drugs to manage the patients with COVID-19.

DOI: 10.3831/KPI.2020.23.010
PubMed: 32685234
PubMed Central: PMC7338708

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<author><name sortKey="Maideen, Naina Mohamed Pakkir" sort="Maideen, Naina Mohamed Pakkir" uniqKey="Maideen N" first="Naina Mohamed Pakkir" last="Maideen">Naina Mohamed Pakkir Maideen</name>
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<country xml:lang="fr">Émirats arabes unis</country>
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<front><div type="abstract" xml:lang="en">Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Currently, the management of patients with COVID-19 depends mainly on repurposed drugs which include chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β and others. In this review, the potential of Nigella sativa (black cumin seeds) to treat the patients with COVID-19 analyzed, as it has shown to possess antiviral, antioxidant, anti-inflammatory, anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic and analgesic activities. PubMed, Google Scholar, Science Direct, Directory of open access journals (DOAJ) and reference lists were searched to identify articles associated with antiviral and other properties of N.sativa related to the signs and symptoms of COVID-19. Various randomized controlled trials, pilot studies, case reports and in vitro and in vivo studies confirmed that N.sativa has antiviral, antioxidant, anti-inflammatory, immunomodulatory, bronchodilatory, antihistaminic, antitussive activities related to causative oraganism and signs and symptoms of COVID-19. <i>N. sativa</i>
 could be used as an adjuvant therapy along with repurposed conventional drugs to manage the patients with COVID-19.</div>
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<Title>Journal of pharmacopuncture</Title>
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<Abstract><AbstractText>Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Currently, the management of patients with COVID-19 depends mainly on repurposed drugs which include chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β and others. In this review, the potential of Nigella sativa (black cumin seeds) to treat the patients with COVID-19 analyzed, as it has shown to possess antiviral, antioxidant, anti-inflammatory, anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic and analgesic activities. PubMed, Google Scholar, Science Direct, Directory of open access journals (DOAJ) and reference lists were searched to identify articles associated with antiviral and other properties of N.sativa related to the signs and symptoms of COVID-19. Various randomized controlled trials, pilot studies, case reports and in vitro and in vivo studies confirmed that N.sativa has antiviral, antioxidant, anti-inflammatory, immunomodulatory, bronchodilatory, antihistaminic, antitussive activities related to causative oraganism and signs and symptoms of COVID-19. <i>N. sativa</i>
 could be used as an adjuvant therapy along with repurposed conventional drugs to manage the patients with COVID-19.</AbstractText>
<CopyrightInformation>© 2020 Korean Pharmacopuncture Institute.</CopyrightInformation>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Maideen</LastName>
<ForeName>Naina Mohamed Pakkir</ForeName>
<Initials>NMP</Initials>
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<CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Pharmacopuncture. 2020 Sep 30;23(3):179</RefSource>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Anti-inflammatory</Keyword>
<Keyword MajorTopicYN="N">Anticoagulant</Keyword>
<Keyword MajorTopicYN="N">Antioxidant</Keyword>
<Keyword MajorTopicYN="N">Antiviral</Keyword>
<Keyword MajorTopicYN="N">Black seeds</Keyword>
<Keyword MajorTopicYN="N">Nigella sativa</Keyword>
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<CoiStatement>Conflict of Interest The authors declare that there are no conflicts of interest.</CoiStatement>
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Prophetic Medicine-Nigella Sativa (Black cumin seeds) - Potential herb for COVID-19?

Prophetic Medicine-Nigella Sativa (Black cumin seeds) - Potential herb for COVID-19?

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