Case Report: Death due to COVID-19 in Three Brothers.
Identifieur interne : 001A05 ( Main/Corpus ); précédent : 001A04; suivant : 001A06Case Report: Death due to COVID-19 in Three Brothers.
Auteurs : Sedigheh Yousefzadegan ; Nima RezaeiSource :
- The American journal of tropical medicine and hygiene [ 1476-1645 ] ; 2020.
English descriptors
- KwdEn :
- Aged (MeSH), Betacoronavirus (genetics), Betacoronavirus (pathogenicity), COVID-19 (MeSH), Coronavirus Infections (diagnostic imaging), Coronavirus Infections (drug therapy), Coronavirus Infections (genetics), Coronavirus Infections (pathology), Fatal Outcome (MeSH), Genetic Predisposition to Disease (MeSH), Humans (MeSH), Hydroxychloroquine (therapeutic use), Iran (MeSH), Lung (diagnostic imaging), Lung (pathology), Lung (virology), Male (MeSH), Middle Aged (MeSH), Oseltamivir (therapeutic use), Pandemics (MeSH), Pneumonia, Viral (diagnostic imaging), Pneumonia, Viral (drug therapy), Pneumonia, Viral (genetics), Pneumonia, Viral (pathology), SARS-CoV-2 (MeSH), Siblings (MeSH), Tomography, X-Ray Computed (MeSH).
- MESH :
- chemical , therapeutic use : Hydroxychloroquine, Oseltamivir.
- geographic : Iran.
- diagnostic imaging : Coronavirus Infections, Lung, Pneumonia, Viral.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus, Coronavirus Infections, Pneumonia, Viral.
- pathogenicity : Betacoronavirus.
- pathology : Coronavirus Infections, Lung, Pneumonia, Viral.
- virology : Lung.
- Aged, COVID-19, Fatal Outcome, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Pandemics, SARS-CoV-2, Siblings, Tomography, X-Ray Computed.
Abstract
We report fatal cases of novel coronavirus disease (COVID-19) in three brothers in Iran. An increased susceptibility to specific pathogens has been reported for a number of genetic defects. Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals.
DOI: 10.4269/ajtmh.20-0240
PubMed: 32277694
PubMed Central: PMC7253136
Links to Exploration step
pubmed:32277694Le document en format XML
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<affiliation><nlm:affiliation>Department of Pediatric Respiratory Medicine, Firouzabadi Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rezaei, Nima" sort="Rezaei, Nima" uniqKey="Rezaei N" first="Nima" last="Rezaei">Nima Rezaei</name>
<affiliation><nlm:affiliation>Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Pediatric Respiratory Medicine, Firouzabadi Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Betacoronavirus (genetics)</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>COVID-19 (MeSH)</term>
<term>Coronavirus Infections (diagnostic imaging)</term>
<term>Coronavirus Infections (drug therapy)</term>
<term>Coronavirus Infections (genetics)</term>
<term>Coronavirus Infections (pathology)</term>
<term>Fatal Outcome (MeSH)</term>
<term>Genetic Predisposition to Disease (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Iran (MeSH)</term>
<term>Lung (diagnostic imaging)</term>
<term>Lung (pathology)</term>
<term>Lung (virology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Oseltamivir (therapeutic use)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (diagnostic imaging)</term>
<term>Pneumonia, Viral (drug therapy)</term>
<term>Pneumonia, Viral (genetics)</term>
<term>Pneumonia, Viral (pathology)</term>
<term>SARS-CoV-2 (MeSH)</term>
<term>Siblings (MeSH)</term>
<term>Tomography, X-Ray Computed (MeSH)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Hydroxychloroquine</term>
<term>Oseltamivir</term>
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<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Iran</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lung</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term>
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<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term>
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<term>Lung</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Lung</term>
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<term>COVID-19</term>
<term>Fatal Outcome</term>
<term>Genetic Predisposition to Disease</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
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<front><div type="abstract" xml:lang="en">We report fatal cases of novel coronavirus disease (COVID-19) in three brothers in Iran. An increased susceptibility to specific pathogens has been reported for a number of genetic defects. Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals.</div>
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<Title>The American journal of tropical medicine and hygiene</Title>
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<ArticleTitle>Case Report: Death due to COVID-19 in Three Brothers.</ArticleTitle>
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<Abstract><AbstractText>We report fatal cases of novel coronavirus disease (COVID-19) in three brothers in Iran. An increased susceptibility to specific pathogens has been reported for a number of genetic defects. Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals.</AbstractText>
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<AffiliationInfo><Affiliation>Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.</Affiliation>
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