A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.
Identifieur interne : 001833 ( Main/Corpus ); précédent : 001832; suivant : 001834A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.
Auteurs : Aveek Mukherjee ; Mudassar Ahmad ; Douglas FreniaSource :
- Cureus [ 2168-8184 ] ; 2020.
Abstract
After an outbreak in December 2019 in Wuhan, Hubei Province of China, coronavirus disease 2019 (COVID-19) has rapidly become a pandemic. The 2019 novel coronavirus (2019 nCov), now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a wide spectrum of illness and patients with underlying comorbidities have a high mortality. Here we present a 49-year-old male patient with comorbid conditions who presented with fever, cough, myalgia and shortness of breath for five days with likely exposure to a COVID-19 contact. A computed tomography scan of the thorax revealed multifocal bilateral ground-glass lung opacities with areas of subpleural sparing. He tested positive for SARS-CoV-2 by nucleic acid amplification. Hydroxychloroquine therapy was started, and the patient responded favorably with improvement of symptoms. Early diagnosis and self-isolation or quarantine remain key to stemming the tide of the contagion as there is a real risk of the healthcare system being overwhelmed.
DOI: 10.7759/cureus.7473
PubMed: 32351851
PubMed Central: PMC7187998
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.</title><author><name sortKey="Mukherjee, Aveek" sort="Mukherjee, Aveek" uniqKey="Mukherjee A" first="Aveek" last="Mukherjee">Aveek Mukherjee</name><affiliation><nlm:affiliation>Internal Medicine, Saint Peter's University Hospital/Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ahmad, Mudassar" sort="Ahmad, Mudassar" uniqKey="Ahmad M" first="Mudassar" last="Ahmad">Mudassar Ahmad</name><affiliation><nlm:affiliation>Pulmonary Medicine, Saint Peter's University Hospital/Rutgers University, New Brunswick, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Frenia, Douglas" sort="Frenia, Douglas" uniqKey="Frenia D" first="Douglas" last="Frenia">Douglas Frenia</name><affiliation><nlm:affiliation>Pulmonary Critical Care, Saint Peter's University Hospital, New Brunswick, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32351851</idno><idno type="pmid">32351851</idno><idno type="doi">10.7759/cureus.7473</idno><idno type="pmc">PMC7187998</idno><idno type="wicri:Area/Main/Corpus">001833</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001833</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.</title><author><name sortKey="Mukherjee, Aveek" sort="Mukherjee, Aveek" uniqKey="Mukherjee A" first="Aveek" last="Mukherjee">Aveek Mukherjee</name><affiliation><nlm:affiliation>Internal Medicine, Saint Peter's University Hospital/Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ahmad, Mudassar" sort="Ahmad, Mudassar" uniqKey="Ahmad M" first="Mudassar" last="Ahmad">Mudassar Ahmad</name><affiliation><nlm:affiliation>Pulmonary Medicine, Saint Peter's University Hospital/Rutgers University, New Brunswick, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Frenia, Douglas" sort="Frenia, Douglas" uniqKey="Frenia D" first="Douglas" last="Frenia">Douglas Frenia</name><affiliation><nlm:affiliation>Pulmonary Critical Care, Saint Peter's University Hospital, New Brunswick, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Cureus</title><idno type="ISSN">2168-8184</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">After an outbreak in December 2019 in Wuhan, Hubei Province of China, coronavirus disease 2019 (COVID-19) has rapidly become a pandemic. The 2019 novel coronavirus (2019 nCov), now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a wide spectrum of illness and patients with underlying comorbidities have a high mortality. Here we present a 49-year-old male patient with comorbid conditions who presented with fever, cough, myalgia and shortness of breath for five days with likely exposure to a COVID-19 contact. A computed tomography scan of the thorax revealed multifocal bilateral ground-glass lung opacities with areas of subpleural sparing. He tested positive for SARS-CoV-2 by nucleic acid amplification. Hydroxychloroquine therapy was started, and the patient responded favorably with improvement of symptoms. Early diagnosis and self-isolation or quarantine remain key to stemming the tide of the contagion as there is a real risk of the healthcare system being overwhelmed.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32351851</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>28</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2168-8184</ISSN><JournalIssue CitedMedium="Print"><Volume>12</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>Mar</Month><Day>30</Day></PubDate></JournalIssue><Title>Cureus</Title><ISOAbbreviation>Cureus</ISOAbbreviation></Journal><ArticleTitle>A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.</ArticleTitle><Pagination><MedlinePgn>e7473</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.7759/cureus.7473</ELocationID><Abstract><AbstractText>After an outbreak in December 2019 in Wuhan, Hubei Province of China, coronavirus disease 2019 (COVID-19) has rapidly become a pandemic. The 2019 novel coronavirus (2019 nCov), now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a wide spectrum of illness and patients with underlying comorbidities have a high mortality. Here we present a 49-year-old male patient with comorbid conditions who presented with fever, cough, myalgia and shortness of breath for five days with likely exposure to a COVID-19 contact. A computed tomography scan of the thorax revealed multifocal bilateral ground-glass lung opacities with areas of subpleural sparing. He tested positive for SARS-CoV-2 by nucleic acid amplification. Hydroxychloroquine therapy was started, and the patient responded favorably with improvement of symptoms. Early diagnosis and self-isolation or quarantine remain key to stemming the tide of the contagion as there is a real risk of the healthcare system being overwhelmed.</AbstractText><CopyrightInformation>Copyright © 2020, Mukherjee et al.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mukherjee</LastName><ForeName>Aveek</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Internal Medicine, Saint Peter's University Hospital/Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahmad</LastName><ForeName>Mudassar</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Pulmonary Medicine, Saint Peter's University Hospital/Rutgers University, New Brunswick, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frenia</LastName><ForeName>Douglas</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Pulmonary Critical Care, Saint Peter's University Hospital, New Brunswick, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Cureus</MedlineTA><NlmUniqueID>101596737</NlmUniqueID><ISSNLinking>2168-8184</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">2019 novel coronavirus</Keyword><Keyword MajorTopicYN="N">2019-ncov</Keyword><Keyword MajorTopicYN="N">cov</Keyword><Keyword MajorTopicYN="N">covid-19</Keyword><Keyword MajorTopicYN="N">ground-glass opacity</Keyword><Keyword MajorTopicYN="N">hydroxychloroquine</Keyword><Keyword MajorTopicYN="N">multifocal</Keyword><Keyword MajorTopicYN="N">pneumonia</Keyword><Keyword MajorTopicYN="N">sars-cov-2 (severe acute respiratory syndrome coronavirus -2)</Keyword><Keyword MajorTopicYN="N">wuhan</Keyword></KeywordList><CoiStatement>The authors have declared that no competing interests exist.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32351851</ArticleId><ArticleId IdType="doi">10.7759/cureus.7473</ArticleId><ArticleId IdType="pmc">PMC7187998</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Mil Med Res. 2020 Mar 13;7(1):11</Citation><ArticleIdList><ArticleId IdType="pubmed">32169119</ArticleId></ArticleIdList></Reference><Reference><Citation>mSphere. 2020 Mar 18;5(2):</Citation><ArticleIdList><ArticleId IdType="pubmed">32188753</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Mar 5;382(10):929-936</Citation><ArticleIdList><ArticleId IdType="pubmed">32004427</ArticleId></ArticleIdList></Reference><Reference><Citation>AJR Am J Roentgenol. 2020 Mar 14;:1-7</Citation><ArticleIdList><ArticleId IdType="pubmed">32174129</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2020 Feb 15;395(10223):507-513</Citation><ArticleIdList><ArticleId IdType="pubmed">32007143</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Infect Dis. 2020 Mar 09;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32150618</ArticleId></ArticleIdList></Reference><Reference><Citation>Anaesthesiol Intensive Ther. 2020;52(1):34-41</Citation><ArticleIdList><ArticleId IdType="pubmed">32191830</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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