CovidChloroV1, Main, Corpus, bibRecord, 001448

Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.

Identifieur interne : 001448 ( Main/Corpus ); précédent : 001447; suivant : 001449

Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.

Auteurs : Edgard Torres Dos Reis Neto ; Adriana Maria Kakehasi ; Marcelo De Medeiros Pinheiro ; Gilda Aparecida Ferreira ; Cláudia Diniz Lopes Marques ; Licia Maria Henrique Da Mota ; Eduardo Dos Santos Paiva ; Gecilmara Cristina Salviato Pileggi ; Emília Inoue Sato ; Ana Paula Monteiro Gomides Reis ; Ricardo Machado Xavier ; José Roberto Provenza

Source :

Advances in rheumatology (London, England) [ 2523-3106 ] ; 2020.

RBID : pubmed:32517786

English descriptors

KwdEn :
- Antimalarials (pharmacology), Antiphospholipid Syndrome (drug therapy), Antiphospholipid Syndrome (immunology), Antirheumatic Agents (therapeutic use), Arthritis, Rheumatoid (drug therapy), Arthritis, Rheumatoid (immunology), COVID-19 (MeSH), Chloroquine (pharmacology), Coronavirus Infections (drug therapy), Drug Eruptions (etiology), Drug Interactions (MeSH), Female (MeSH), Glucose (metabolism), Heart Diseases (chemically induced), Humans (MeSH), Hydroxychloroquine (pharmacology), Lipids (blood), Lupus Erythematosus, Cutaneous (drug therapy), Lupus Erythematosus, Cutaneous (immunology), Lupus Erythematosus, Systemic (drug therapy), Lupus Erythematosus, Systemic (immunology), Lupus Erythematosus, Systemic (mortality), Male (MeSH), Pandemics (MeSH), Platelet Aggregation (drug effects), Pneumonia, Viral (drug therapy), Pregnancy (MeSH), Renal Insufficiency (prevention & control), Retinal Diseases (chemically induced), Sjogren's Syndrome (drug therapy), Sjogren's Syndrome (immunology).
MESH :
- chemical , blood : Lipids.
- chemical , metabolism : Glucose.
- chemical , pharmacology : Antimalarials, Chloroquine, Hydroxychloroquine.
- chemically induced : Heart Diseases, Retinal Diseases.
- drug effects : Platelet Aggregation.
- drug therapy : Antiphospholipid Syndrome, Arthritis, Rheumatoid, Coronavirus Infections, Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Systemic, Pneumonia, Viral, Sjogren's Syndrome.
- etiology : Drug Eruptions.
- immunology : Antiphospholipid Syndrome, Arthritis, Rheumatoid, Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Systemic, Sjogren's Syndrome.
- mortality : Lupus Erythematosus, Systemic.
- prevention & control : Renal Insufficiency.
- chemical , therapeutic use : Antirheumatic Agents.
- COVID-19, Drug Interactions, Female, Humans, Male, Pandemics, Pregnancy.

Abstract

Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.

DOI: 10.1186/s42358-020-00134-8
PubMed: 32517786
PubMed Central: PMC7282202

Links to Exploration step

pubmed:32517786

Le document en format XML

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<author><name sortKey="De Medeiros Pinheiro, Marcelo" sort="De Medeiros Pinheiro, Marcelo" uniqKey="De Medeiros Pinheiro M" first="Marcelo" last="De Medeiros Pinheiro">Marcelo De Medeiros Pinheiro</name>
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</affiliation>
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<author><name sortKey="Dos Santos Paiva, Eduardo" sort="Dos Santos Paiva, Eduardo" uniqKey="Dos Santos Paiva E" first="Eduardo" last="Dos Santos Paiva">Eduardo Dos Santos Paiva</name>
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<author><name sortKey="Pileggi, Gecilmara Cristina Salviato" sort="Pileggi, Gecilmara Cristina Salviato" uniqKey="Pileggi G" first="Gecilmara Cristina Salviato" last="Pileggi">Gecilmara Cristina Salviato Pileggi</name>
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<author><name sortKey="Sato, Emilia Inoue" sort="Sato, Emilia Inoue" uniqKey="Sato E" first="Emília Inoue" last="Sato">Emília Inoue Sato</name>
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<author><name sortKey="Reis, Ana Paula Monteiro Gomides" sort="Reis, Ana Paula Monteiro Gomides" uniqKey="Reis A" first="Ana Paula Monteiro Gomides" last="Reis">Ana Paula Monteiro Gomides Reis</name>
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</affiliation>
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<author><name sortKey="Xavier, Ricardo Machado" sort="Xavier, Ricardo Machado" uniqKey="Xavier R" first="Ricardo Machado" last="Xavier">Ricardo Machado Xavier</name>
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</affiliation>
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<author><name sortKey="Provenza, Jose Roberto" sort="Provenza, Jose Roberto" uniqKey="Provenza J" first="José Roberto" last="Provenza">José Roberto Provenza</name>
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<idno type="eISSN">2523-3106</idno>
<imprint><date when="2020" type="published">2020</date>
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<term>Antirheumatic Agents (therapeutic use)</term>
<term>Arthritis, Rheumatoid (drug therapy)</term>
<term>Arthritis, Rheumatoid (immunology)</term>
<term>COVID-19 (MeSH)</term>
<term>Chloroquine (pharmacology)</term>
<term>Coronavirus Infections (drug therapy)</term>
<term>Drug Eruptions (etiology)</term>
<term>Drug Interactions (MeSH)</term>
<term>Female (MeSH)</term>
<term>Glucose (metabolism)</term>
<term>Heart Diseases (chemically induced)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (pharmacology)</term>
<term>Lipids (blood)</term>
<term>Lupus Erythematosus, Cutaneous (drug therapy)</term>
<term>Lupus Erythematosus, Cutaneous (immunology)</term>
<term>Lupus Erythematosus, Systemic (drug therapy)</term>
<term>Lupus Erythematosus, Systemic (immunology)</term>
<term>Lupus Erythematosus, Systemic (mortality)</term>
<term>Male (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Platelet Aggregation (drug effects)</term>
<term>Pneumonia, Viral (drug therapy)</term>
<term>Pregnancy (MeSH)</term>
<term>Renal Insufficiency (prevention & control)</term>
<term>Retinal Diseases (chemically induced)</term>
<term>Sjogren's Syndrome (drug therapy)</term>
<term>Sjogren's Syndrome (immunology)</term>
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<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Heart Diseases</term>
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<term>Arthritis, Rheumatoid</term>
<term>Coronavirus Infections</term>
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<term>Lupus Erythematosus, Systemic</term>
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<front><div type="abstract" xml:lang="en">Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.</div>
</front>
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<DateCompleted><Year>2020</Year>
<Month>06</Month>
<Day>24</Day>
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<DateRevised><Year>2020</Year>
<Month>12</Month>
<Day>18</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2523-3106</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>60</Volume>
<Issue>1</Issue>
<PubDate><Year>2020</Year>
<Month>06</Month>
<Day>09</Day>
</PubDate>
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<Title>Advances in rheumatology (London, England)</Title>
<ISOAbbreviation>Adv Rheumatol</ISOAbbreviation>
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<ArticleTitle>Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.</ArticleTitle>
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<Abstract><AbstractText>Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.</AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dos Reis Neto</LastName>
<ForeName>Edgard Torres</ForeName>
<Initials>ET</Initials>
<AffiliationInfo><Affiliation>Disciplina de Reumatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Kakehasi</LastName>
<ForeName>Adriana Maria</ForeName>
<Initials>AM</Initials>
<Identifier Source="ORCID">0000-0001-9411-7493</Identifier>
<AffiliationInfo><Affiliation>Serviço de Reumatologia do Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. amkakehasi@gmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Medeiros Pinheiro</LastName>
<ForeName>Marcelo</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Disciplina de Reumatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Ferreira</LastName>
<ForeName>Gilda Aparecida</ForeName>
<Initials>GA</Initials>
<AffiliationInfo><Affiliation>Serviço de Reumatologia do Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Marques</LastName>
<ForeName>Cláudia Diniz Lopes</ForeName>
<Initials>CDL</Initials>
<AffiliationInfo><Affiliation>Serviço de Reumatologia do Hospital das Clínicas da Universidade Federal de Pernambuco, Recife, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>da Mota</LastName>
<ForeName>Licia Maria Henrique</ForeName>
<Initials>LMH</Initials>
<AffiliationInfo><Affiliation>Hospital Universitário - UnB/EBSERH, Brasília, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Dos Santos Paiva</LastName>
<ForeName>Eduardo</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Serviço de Reumatologia do Hospital das Clínicas da Universidade Federal do Paraná, Curitiba, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pileggi</LastName>
<ForeName>Gecilmara Cristina Salviato</ForeName>
<Initials>GCS</Initials>
<AffiliationInfo><Affiliation>Instituto de Ensino e Pesquisa (IEP), Hospital Amor, Barretos, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sato</LastName>
<ForeName>Emília Inoue</ForeName>
<Initials>EI</Initials>
<AffiliationInfo><Affiliation>Disciplina de Reumatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Reis</LastName>
<ForeName>Ana Paula Monteiro Gomides</ForeName>
<Initials>APMG</Initials>
<AffiliationInfo><Affiliation>Hospital Universitário - UnB/EBSERH, Brasília, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xavier</LastName>
<ForeName>Ricardo Machado</ForeName>
<Initials>RM</Initials>
<AffiliationInfo><Affiliation>Serviço de Reumatologia do Hospital de Clínicas de Porto Alegre da Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Provenza</LastName>
<ForeName>José Roberto</ForeName>
<Initials>JR</Initials>
<AffiliationInfo><Affiliation>Pontifícia Universidade Católica de Campinas, Campinas, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
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<PublicationType UI="D000078182">Systematic Review</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>06</Month>
<Day>09</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Adv Rheumatol</MedlineTA>
<NlmUniqueID>101734172</NlmUniqueID>
<ISSNLinking>2523-3106</ISSNLinking>
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<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
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Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.

Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.

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