COVID-19 research: an opinion piece.
Identifieur interne : 001397 ( Main/Corpus ); précédent : 001396; suivant : 001398COVID-19 research: an opinion piece.
Auteurs : L. Waters ; J K RockstrohSource :
- HIV medicine [ 1468-1293 ] ; 2020.
English descriptors
- KwdEn :
- Anti-Retroviral Agents (therapeutic use), Betacoronavirus (drug effects), COVID-19 (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (prevention & control), Drug Combinations (MeSH), Drug Repositioning (standards), Drug Repositioning (trends), Humans (MeSH), Hydroxychloroquine (therapeutic use), Lopinavir (therapeutic use), Pandemics (prevention & control), Pneumonia, Viral (drug therapy), Pneumonia, Viral (prevention & control), Research (standards), Research (trends), Ritonavir (therapeutic use), SARS-CoV-2 (MeSH), Tenofovir (therapeutic use), Time Factors (MeSH).
- MESH :
- chemical , therapeutic use : Anti-Retroviral Agents, Hydroxychloroquine, Lopinavir, Ritonavir, Tenofovir.
- drug effects : Betacoronavirus.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- standards : Drug Repositioning, Research.
- trends : Drug Repositioning, Research.
- COVID-19, Drug Combinations, Humans, SARS-CoV-2, Time Factors.
Abstract
The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel infection outbreaks, antiretrovirals are just one drug class that has been held up as a potential strategy for prophylaxis and treatment with scant evidence and risk of harm. Here we summarize the evidence for antiretrovirals to treat COVID-19 and, as a drug that has also been studied in HIV, hydroxychloroquine, and flag some of the pitfalls of using therapies that have not been evaluated robustly.
DOI: 10.1111/hiv.12913
PubMed: 32544304
PubMed Central: PMC7323295
Links to Exploration step
pubmed:32544304Le document en format XML
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<term>Coronavirus Infections (prevention & control)</term>
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<front><div type="abstract" xml:lang="en">The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel infection outbreaks, antiretrovirals are just one drug class that has been held up as a potential strategy for prophylaxis and treatment with scant evidence and risk of harm. Here we summarize the evidence for antiretrovirals to treat COVID-19 and, as a drug that has also been studied in HIV, hydroxychloroquine, and flag some of the pitfalls of using therapies that have not been evaluated robustly.</div>
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<Abstract><AbstractText>The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel infection outbreaks, antiretrovirals are just one drug class that has been held up as a potential strategy for prophylaxis and treatment with scant evidence and risk of harm. Here we summarize the evidence for antiretrovirals to treat COVID-19 and, as a drug that has also been studied in HIV, hydroxychloroquine, and flag some of the pitfalls of using therapies that have not been evaluated robustly.</AbstractText>
<CopyrightInformation>© 2020 British HIV Association.</CopyrightInformation>
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