A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance.
Identifieur interne : 001343 ( Main/Corpus ); précédent : 001342; suivant : 001344A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance.
Auteurs : Byeong Yun Ahn ; Chang Kyung Kang ; Jong Do Seo ; Pyoeng Gyun Choe ; Sang Hoon Song ; Wan Beom Park ; Sang Won Park ; Nam Joong Kim ; Myoung Don OhSource :
- Journal of Korean medical science [ 1598-6357 ] ; 2020.
English descriptors
- KwdEn :
- Adenosine Monophosphate (analogs & derivatives), Adenosine Monophosphate (therapeutic use), Alanine (analogs & derivatives), Alanine (therapeutic use), Antiviral Agents (therapeutic use), Azithromycin (therapeutic use), Betacoronavirus (drug effects), COVID-19 (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (prevention & control), Female (MeSH), Humans (MeSH), Hydroxychloroquine (therapeutic use), Middle Aged (MeSH), Pandemics (prevention & control), Pneumonia, Viral (drug therapy), Pneumonia, Viral (prevention & control), Primary Prevention (methods), SARS-CoV-2 (MeSH).
- MESH :
- chemical , analogs & derivatives : Adenosine Monophosphate, Alanine.
- chemical , therapeutic use : Adenosine Monophosphate, Alanine, Antiviral Agents, Azithromycin, Hydroxychloroquine.
- drug effects : Betacoronavirus.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- methods : Primary Prevention.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- COVID-19, Female, Humans, Middle Aged, SARS-CoV-2.
Abstract
There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.
DOI: 10.3346/jkms.2020.35.e231
PubMed: 32567262
PubMed Central: PMC7308141
Links to Exploration step
pubmed:32567262Le document en format XML
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<term>Female (MeSH)</term>
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<front><div type="abstract" xml:lang="en">There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.</div>
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<Abstract><AbstractText>There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.</AbstractText>
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