Clinical and biological data on the use of hydroxychloroquine against SARS-CoV-2 could support the role of the NLRP3 inflammasome in the pathogenesis of respiratory disease.
Identifieur interne : 001308 ( Main/Corpus ); précédent : 001307; suivant : 001309Clinical and biological data on the use of hydroxychloroquine against SARS-CoV-2 could support the role of the NLRP3 inflammasome in the pathogenesis of respiratory disease.
Auteurs : Alessandro Lucchesi ; Paolo Silimbani ; Gerardo Musuraca ; Claudio Cerchione ; Giovanni Martinelli ; Paola Di Carlo ; Mariasanta NapolitanoSource :
- Journal of medical virology [ 1096-9071 ] ; 2021.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : NLR Family, Pyrin Domain-Containing 3 Protein.
- chemical , pharmacology : Hydroxychloroquine.
- drug therapy : COVID-19.
- Humans, Inflammasomes, SARS-CoV-2.
DOI: 10.1002/jmv.26217
PubMed: 32579244
PubMed Central: PMC7361389
Links to Exploration step
pubmed:32579244Le document en format XML
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<author><name sortKey="Martinelli, Giovanni" sort="Martinelli, Giovanni" uniqKey="Martinelli G" first="Giovanni" last="Martinelli">Giovanni Martinelli</name>
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<author><name sortKey="Di Carlo, Paola" sort="Di Carlo, Paola" uniqKey="Di Carlo P" first="Paola" last="Di Carlo">Paola Di Carlo</name>
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<author><name sortKey="Napolitano, Mariasanta" sort="Napolitano, Mariasanta" uniqKey="Napolitano M" first="Mariasanta" last="Napolitano">Mariasanta Napolitano</name>
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<term>NLR Family, Pyrin Domain-Containing 3 Protein (genetics)</term>
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<ReferenceList><Title>REFERENCES</Title>
<Reference><Citation>Sarma P, Kaur H, Kumar H, et al. Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: a systematic review and meta-analysis. J Med Virol. 2020;92(7):776-785. https://doi.org/10.1002/jmv.25898</Citation>
</Reference>
<Reference><Citation>He L, Ding Y, Zhang Q, et al. Expression of elevated levels of proinflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS. J Pathol. 2006;210(3):288-297. https://doi.org/10.1002/path.2067</Citation>
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<Reference><Citation>Wang Z, Zhang S, Xiao Y, et al. NLRP3 inflammasome and inflammatory diseases. Oxid Med Cell Longev. 2020;2020:4063562. https://doi.org/10.1155/2020/4063562</Citation>
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<Reference><Citation>Hosseinian N, Cho Y, Lockey RF, Kolliputi N. The role of the NLRP3 inflammasome in pulmonary diseases. Ther Adv Respir Dis. 2015;9(4):188-197. https://doi.org/10.1177/1753465815586335</Citation>
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<Reference><Citation>Yuen KS, Ye ZW, Fung SY, Chan CP, Jin DY. SARS-CoV-2 and COVID-19: the most important research questions. Cell Biosci. 2020;10:40. https://doi.org/10.1186/s13578-020-00404-4</Citation>
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<Reference><Citation>Zhao C, Zhao W. NLRP3 inflammasome-A key player in antiviral responses. Front Immunol. 2020;11:211. https://doi.org/10.3389/fimmu.2020.00211</Citation>
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<Reference><Citation>Grailer JJ, Canning BA, Kalbitz M, et al. Critical role for the NLRP3 inflammasome during acute lung injury. J Immunol. 2014;192(12):5974-5983. https://doi.org/10.4049/jimmunol.1400368</Citation>
</Reference>
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